OnAir, with Clinical Respiratory News Clinical Respiratory News

In this episode of OnAir, sleep clinician Prof. Dr Manuel Sánchez-de-la-Torre and host Daniela Ehrsam-Tosi discuss the potential benefits of patient phenotyping for obstructive sleep apnoea.
Prof. Dr Sánchez-de-la-Torre explores why patient phenotyping can be relevant during diagnosis, for making effective treatment decisions, and during the follow-up stage. He highlights the role of patient phenotype in predicting responses and understanding neutral effects, with a particular focus on blood pressure and hypoxic burden. He also emphasises the value of telemedicine in promoting engagement and treatment adherence.
Listen to learn why progress in patient phenotyping could affect the way you treat and understand your OSA patients.
Reference:
Sánchez-de-la-Torre M, Gracia-Lavedan E, Benitez ID, et al. Adherence to CPAP Treatment and the Risk of Recurrent Cardiovascular Events: A Meta-Analysis. JAMA. 2023;330(13):1255–1265. https://doi.org/10.1001/jama.2023.17465
Listen to OnAir with Clinical Respiratory News, the podcast that brings you fresh insights and thought-provoking discussions about hot topics in respiratory care and sleep-disordered breathing.
Disclaimers:
This content is intended for health professionals only.
This testimonial is a genuine and documented account of the individual’s response to treatment. Outcomes and results may vary, and this individual’s response does not provide any indication, warranty or guarantee that other people will have the same or a similar experience. This presentation is based on the professional presenter experience, practice and on recent available relevant data which is not intended to be understood as state of the art.
Professor Manuel Sánchez-de-la-Torre was provided with a nominal financial incentive for providing the following testimonial. Professor Manuel Sánchez-de-la-Torre will not receive any discounts or further incentives as a result of this testimonial.

In this episode of OnAir, clinical expert Professor Christoph Schöbel and host Daniela Ehrsam-Tosi discuss sleep quality and sleep disorders.
There’s a growing awareness of the importance of sleep for our cardiovascular system and our general health and wellbeing. At the same time, our ability to get good sleep is increasingly challenged by everything from late-night scrolling to irregular work schedules, stress and anxiety. It’s thought that 10-30% of people worldwide suffer from insomnia1, not to mention other sleep disorders like OSA and restless leg syndrome.
In this context, which diagnostic and treatment pathways should we be prioritising? Should primary care screening programmes focus on sleep as well as diet and exercise? What benefits might digital technology have to offer? Professor Schöbel shares his thoughts on these points, as well as discussing the new European Insomnia Guideline2 and the challenges of treating COMISA (co-morbid insomnia and sleep apnoea).
References and useful links:
1. Bhaskar S, Hemavathy D, Prasad S. Prevalence of chronic insomnia in adult patients and its correlation with medical comorbidities. J Family Med Prim Care. 2016 Oct-Dec;5(4):780-784. https://10.4103/2249-4863.201153. PMID: 28348990; PMCID: PMC5353813.
2. Riemann, D., Espie, C. A., Altena, E., Arnardottir, E. S., Baglioni, C., Bassetti, C. L. A., Bastien, C., Berzina, N., Bjorvatn, B., Dikeos, D., Dolenc Groselj, L., Ellis, J. G., Garcia-Borreguero, D., Geoffroy, P. A., Gjerstad, M., Gonçalves, M., Hertenstein, E., Hoedlmoser, K., Hion, T., … Spiegelhalder, K. (2023). The European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023. Journal of Sleep Research, 32(6), e14035. https://doi.org/10.1111/jsr.14035
Listen to OnAir with Clinical Respiratory News, the podcast that brings you fresh insights and thought-provoking discussions about hot topics in respiratory care and sleep-disordered breathing.
Disclaimers:
This content is intended for health professionals only.
This testimonial is a genuine and documented account of the individual’s response to treatment. Outcomes and results may vary, and this individual’s response does not provide any indication, warranty or guarantee that other people will have the same or a similar experience. This presentation is based on the professional presenter experience, practice and on recent available relevant data which is not intended to be understood as state of the art.
Professor Christoph Schöbel was provided with a nominal financial incentive for providing the following testimonial. Professor Christoph Schöbel will not receive any discounts or further incentives as a result of this testimonial.

In this episode of OnAir, we ask whether treatment-adherent OSA patients could be lowering their cardiovascular risk while they sleep. Professor Frédéric Gagnadoux and host Nina Wiklund explore the design, results and implications of his recent 5,000-patient cohort study, which indicates that CPAP can deliver a significant reduction in major adverse cardiovascular events. They ask which patients are likely to benefit, discuss the importance of hours of usage, and consider the tools that clinicians can use to support therapy adherence. Listen to learn about the potential impact of CPAP therapy on the cardiovascular health of your OSA patients.
References and useful links:
Gerves-Pinquie C, Bailly S, Goupil F, Pigeanne T, Launois S, Leclair-Visonneau L, et al.; Pays de la Loire Sleep Cohort Study Group. (2022). Positive airway pressure adherence, mortality and cardiovascular events in sleep apnea patients. Am J Respir Crit Care Med, 206, pp. 1393–1404. DOI: 1164/rccm.202202-0366OC
Sánchez-de-la-Torre M, Gracia-Lavedan E, Benitez ID, et al. Adherence to CPAP Treatment and the Risk of Recurrent Cardiovascular Events: A Meta-Analysis. 2023;330(13):1255–1265. doi:10.1001/jama.2023.17465
ERS 2023 Workshop: CPAP therapy and cardiovascular outcomes – what have we learned from real-life cohorts?
Listen to OnAir with Clinical Respiratory News, the podcast that brings you fresh insights and thought-provoking discussions about hot topics in respiratory care and sleep-disordered breathing.
Disclaimers:
This content is intended for health professionals only.
This testimonial is a genuine and documented account of the individual’s response to treatment. Outcomes and results may vary, and this individual’s response does not provide any indication, warranty or guarantee that other people will have the same or a similar experience. This presentation is based on the professional presenter experience, practice and on recent available relevant data which is not intended to be understood as state of the art.
Professor Frédéric Gagnadoux was provided with a nominal financial incentive for providing the following testimonial. Professor Frédéric Gagnadoux will not receive any discounts or further incentives as a result of this testimonial.

The world has changed profoundly in the 25 years since the internet became mainstream. Is it finally healthcare’s turn to experience a dramatic data-driven transformation? Daniela Ehrsam-Tosi and ResMed’s Chief Medical Officer Carlos Nunez explore the risks, realities and research potential of real-world data and deep machine learning. Their discussion starts with the perennial challenges of rising healthcare costs and ageing populations and invites us to look to a future where our data isn’t just used to serve us relevant advertising, but can also provide us with personalised healthcare in almost real time.
Listen to OnAir with Clinical Respiratory News, the podcast that brings you fresh insights and thought-provoking discussions about hot topics in respiratory care and sleep-disordered breathing.
Disclaimers:
This content is intended for health professionals only.
This testimonial is a genuine and documented account of the individual’s response to treatment. Outcomes and results may vary, and this individual’s response does not provide any indication, warranty or guarantee that other people will have the same or a similar experience. This presentation is based on the professional presenter experience, practice and on recent available relevant data which is not intended to be understood as state of the art.

Which factors make a real difference when it comes to keeping NIV patients comfortable, motivated and well cared for at home? In this episode of the OnAir podcast, respiratory expert Dr Jean-Michel Arnal and host Nina Wiklund discuss key issues in the delivery of home NIV, with a particular focus on troubleshooting, telemonitoring and patient engagement.
As an ICU physician and the author of both a popular book1 and a recent article on home ventilation monitoring2, Dr Arnal has a deep interest and extensive experience in this field. He shares insights on using ventilator waveforms to identify common asynchronies, explains why the cycle feature is so important for patient comfort, and argues that our focus on finding data-driven predictors of exacerbation might be causing us to overlook an important low-tech solution.
Listen now for an engaging tour of key topics in home NIV that provides useful insights for NIV experts while remaining accessible to anyone looking to learn more about the subject.
Monitoring Mechanical Ventilation using Ventilator Waveforms, Springer: https://link.springer.com/book/10.1007/978-3-319-58655-7
Arnal J-M, Oranger M, Gonzalez-Bermejo J. Monitoring Systems in Home Ventilation. Journal of Clinical Medicine. 2023; 12(6):2163. https://doi.org/10.3390/jcm12062163
Listen to OnAir with Clinical Respiratory News, the podcast that brings you fresh insights and thought-provoking discussions about hot topics in respiratory care and sleep-disordered breathing.
Disclaimers:
This content is intended for health professionals only.
This testimonial is a genuine and documented account of the individual’s response to treatment. Outcomes and results may vary, and this individual’s response does not provide any indication, warranty or guarantee that other people will have the same or a similar experience. This presentation is based on the professional presenter experience, practice and on recent available relevant data which is not intended to be understood as state of the art.
Dr Jean-Michel Arnal was provided with a nominal financial incentive for providing the following testimonial. Dr Jean-Michel Arnal will not receive any discounts or further incentives as a result of this testimonial.

Whether you attended ERS 2023 in person or are planning to catch up with the presentations and posters online, you won’t want to miss this episode of the OnAir podcast. As well as giving a flavour of the wide variety of topics covered, guests Adam Benjafield and Leanne Kaye share their conference highlights and key takeaways. The discussion ranges from the potential of behavioural science to drive PAP therapy adherence to the importance of personalised therapy, digital health and person-centred care, alongside new perspectives on OSA diagnosis and phenotyping. There’s also time to touch on the rise of HFT, digital health, a couple of eye-catching new studies based on real-world data, and the important relationship between climate and health. What might these developments mean for the future of sleep and respiratory research and therapy? Listen in to find out.
Listen to OnAir with Clinical Respiratory News, the podcast that brings you fresh insights and thought-provoking discussions about hot topics in respiratory care and sleep-disordered breathing.
Disclaimers:
This content is intended for health professionals only.
This testimonial is a genuine and documented account of the individual’s response to treatment. Outcomes and results may vary, and this individual’s response does not provide any indication, warranty or guarantee that other people will have the same or a similar experience. This presentation is based on the professional presenter experience, practice and on recent available relevant data which is not intended to be understood as state of the art.