BC 057 – Pitavastatine pour la prévention de la maladie cardiovasculaire dans l’infection à VIH (étude REPRIEVE)

Dans cette 57e baladodiffusion, le Dr Luc Lanthier discute de prévention de la maladie cardiovasculaire avec une statine, la pitavastatine, chez les personnes vivant avec le VIH, en plus de réviser la littérature médicale de juin et juillet 2023.

Quiz clinique (1 min 31), présentation principale (2 min 08), critique (20 min 00), autres articles (26 min 15), réponse au quiz clinique (30 min 57)

Référence principale :

Grinspoon SK, Fitch KV, Zanni MV, Fichtenbaum CJ, Umbleja T, Aberg JA, et al. Pitavastatin to Prevent Cardiovascular Disease in HIV Infection. N Engl J Med. 2023;389(8):687-699. PubMed PMID: 37486775.

Articles associés : 

Freiberg MS. HIV and Cardiovascular Disease – An Ounce of Prevention. N Engl J Med. 2023;389(8):760-61. PubMed PMID: 37486752.

Shah ASV, Stelzle D, Lee KK, Beck EJ, Alam S, Clifford S, et al. Global Burden of Atherosclerotic Cardiovascular Disease in People Living With HIV: Systematic Review and Meta-Analysis. Circulation. 2018;138(11):1100-12. PubMed PMID: 29967196.

Hsue PY, Waters DD. Time to Recognize HIV Infection as a Major Cardiovascular Risk Factor. Circulation. 2018;138(11):1113-5. PubMed PMID: 30354392.

Ntsekhe M, Baker JV. Cardiovascular Disease Among Persons Living With HIV: New Insights Into Pathogenesis and Clinical Manifestations in a Global Context. Circulation. 2023;147(1):83-100. PubMed PMID: 36576956.

Feinstein MJ, Hsue PY, Benjamin LA, Bloomfield GS, Currier JS, Freiberg MS, et al. Characteristics, Prevention, and Management of Cardiovascular Disease in People Living With HIV: A Scientific Statement From the American Heart Association. Circulation. 2019;140(2). doi: 10.1161/cir.0000000000000695. PubMed PMID : 31154814.

Autres articles d’intérêt récent : 

Simmons D, Immanuel J, Hague WM, Teede H, Nolan CJ, Peek MJ, et al. Treatment of Gestational Diabetes Mellitus Diagnosed Early in Pregnancy. N Engl J Med. 2023;388(23):2132-44. PubMed PMID: 37144983.

Fischer U, Koga M, Strbian D, Branca M, Abend S, Trelle S, et al. Early versus Later Anticoagulation for Stroke with Atrial Fibrillation. N Engl J Med. 2023;388(26):2411-21. PubMed PMID: 37222476.

Schrag D, Uno H, Rosovsky R, Rutherford C, Sanfilippo K, Villano JL, et al. Direct Oral Anticoagulants vs Low-Molecular-Weight Heparin and Recurrent VTE in Patients With Cancer: A Randomized Clinical Trial. JAMA. 2023;329(22):1924-33. PubMed PMID: 37266947.

Brugts JJ, Radhoe SP, Clephas PRD, Aydin D, van Gent MWF, Szymanski MK, et al. Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial. Lancet. 2023;401(10394):2113-23. PubMed PMID: 37220768.

Lincoff AM, Bhasin S, Flevaris P, Mitchell LM, Basaria S, Boden WE, et al. Cardiovascular Safety of Testosterone-Replacement Therapy. N Engl J Med. 2023;389(2):107-17. PubMed PMID: 37326322.

Bhatt SP, Rabe KF, Hanania NA, Vogelmeier CF, Cole J, Bafadhel M, et al. Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts. N Engl J Med. 2023;39(3):205-14. PubMed PMID: 37272521.

Liu S, Yao C, Xie J, Liu H, Wang H, Lin Z, et al. Effect of an Herbal-Based Injection on 28-Day M