5 DAYS AGO

Top 5 Health Trends for 2025

50 min

6 JAN

Stop Wasting Your Money on Vitamins

Welcome back to our podcast, in this episode we discuss the multi-billion dollar sector that is supplementation. Key topics are whether you need a multivitamin within your diet, how the supplement industry is regulated and our stance on the future of supplementation. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:00 - Introduction 00:37 - Why are we discussing multivitamins 01:05 - What is the definition of a vitamin? 02:18 - Regulatory bodies in the UK and USA - MHRA/ FDA 02:53 - What are the rules and regulations surrounding vitamins/ supplements? 10:58 - Does the lack of regulations on these products impact their quality? 13:00 - Why do we take vitamins in the first place? 14:20 - Study that found increased risk of mortality in those taking multivitamins 17:03 - Do we personally take any multivitamins? 19:42 - Bioniq - the personalised supplement company 22:32 - Where did the RDA guidelines come from and are they still relevant today? 22:50 - Why the supplement industry makes the idea of taking vitamins/ supplements so convincing 29:03 - Is there any evidence to suggest that taking vitamin supplements has an impact on preventing chronic diseases? 29:23 - Is taking a vitamin supplement as effective as getting our vitamins from whole food sources? 30:55 - Summary of key points Here are our podcast links: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA https://podcasts.apple.com/us/podcast/the-chemist-couple-podcast/id1773332678 Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://assets.publishing.service.gov.uk/media/5a7b8297e5274a7318b8f20d/Supplements_Summary__Jan_2012__DH_FINAL.doc.pdf - Department of Health- legislation https://www.food.gov.uk/business-guidance/food-supplements#what-a-food-supplement-is - food standards agency https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.14521#:~:text=Individuals%20who%20want%20to%20improve,provisions%20of%20general%20food%20law - British Journal of Pharmacology- vitamin D quality review https://pmc.ncbi.nlm.nih.gov/articles/PMC11208972/#abstract1 - US Cohort multi-vitamin daily use study https://pmc.ncbi.nlm.nih.gov/articles/PMC5998735/ - History of nutrition https://pmc.ncbi.nlm.nih.gov/articles/PMC9174310/#Sec4 - The effect of the food matrix https://pmc.ncbi.nlm.nih.gov/articles/PMC6743828/#sec1 - Dairy food and matrix https://jamanetwork.com/journals/jama/fullarticle/195038 - vitamins for chronic disease prevention https://pmc.ncbi.nlm.nih.gov/articles/PMC2125921/ - dietary selenium use in production Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview

36 min

30/12/2024

Should You Worry About rising Colon Cancer Rates in Younger People? | How To Improve Your Outcomes

Welcome back to our podcast, in this episode we discuss the rising rates of colon cancer in the under 50s. By 2030 colon cancer is expected to be the leading cause of cancer-related deaths in this age group. We explore how we can get screened, the signs and symptoms to look out for and discuss the possible causes of these shocking statistics. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:00 - Introduction 00:47 - Why are we discussing colon cancer rates in young people? 01:55 - Colon cancer vs Bowel cancer - different terminologies USA vs UK 02:10 - Colon cancer statistics 02:42 - Should we be worried about getting colon cancer less than 50 years 06:44 - Limitations to current evidence 08:00 - National bowel screening programmes - USA and UK 12:43 - Signs and symptoms of colon cancer 14:39 - Risk factors for developing colon cancer 15:51 - Does the gut microbiome play a role in the development of early onset colon cancer 18:28 - Importance of maintaining healthy BMI on the development of early onset colon cancer 20:06 - correlation between western diet, UPF on non communicable diseases and colon cancer 22:40 - What should our governments be doing to address this? 25:37 - Summary of key points in podcast Here are our podcast links: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA https://podcasts.apple.com/us/podcast/the-chemist-couple-podcast/id1773332678 Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://www.mdpi.com/2072-6694/13/23/5933 - The role of diet and lifestyle on early onset colon cancer https://pmc.ncbi.nlm.nih.gov/articles/PMC6957737/ - Influence of the gut microbiome, diet and environment on risk of colorectal cancer https://pmc.ncbi.nlm.nih.gov/articles/PMC9745098/#s12 - Fusobacterium nucleatum and colorectal cancer: from phenomenon to mechanism https://www.mdpi.com/2072-6694/13/23/5933 - factors in early onset colon cancer https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045%2824%2900600-4/fulltext - rising colon cancer in young adults Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview

29 min

23/12/2024

How to Lower Your ApoB | Is the Gut Microbiome Involved in Cholesterol Metabolism?

Welcome back to our podcast, in this episode we discuss how we are going to act upon our ApoB results that we shared previously. We aim to apply the current studies to our lifestyle and measure how effective our interventions have been in 3-4 months. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:03 - Introduction 02:35 - How is the microbiome involved in cholesterol metabolism? 03:23- Coprostanol and its role in cholesterol homeostasis 04:27 - Cholesterol entrapment via gut bacteria 05:43 - Secondary bile acids produced by the gut microbiome 08:08 - The importance of a diverse gut microbiome 12:56 - How to increase your plant intake 14:14 - importance of probiotic for gut microbiome diversity 14:40 - prebiotics and the microbiome 15:09 - Can alcohol theoretically decrease the diversity of the gut microbiome? 16:14 - Is it easy for people with IBS to improve their gut microbiome? 18:18 - Fasting window and gut health 19:14 - antibiotic use and the impact on the gut microbiome 21:25 - does decreasing saturated fats in your diet have a direct effect on cholesterol/ APOB levels 24:18 - Impact of exercise on CVD risk, APOB and LDL-C 25:05 - how energy is used during different intensities of exercise - VO2max 31:03 - dietary carbohydrate consumption and its role in CVD risk 36:28 - Summary - what are we going to be doing going forward to improve our biomarkers? 41:05 - outro Here are our podcast links: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA https://podcasts.apple.com/us/podcast/the-chemist-couple-podcast/id1773332678 Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://pmc.ncbi.nlm.nih.gov/articles/PMC4242964/#:~:text=Recently%2C%20regular%20exercise%20has%20been,apoA1%20ratio%20demonstrated%20significant%20interactions - exercise in overweight women on ApoB https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1365-2796.2007.01806.x - exercise on ApoB- predominantly males https://pmc.ncbi.nlm.nih.gov/articles/PMC5972657/#sec4 - saturated fats on ApoB https://pmc.ncbi.nlm.nih.gov/articles/PMC7468809/#sec1-nutrients-12-02204 - Glycaemic index & load on lipid kinetics https://www.ahajournals.org/doi/10.1161/ATVBAHA.120.315766#graphical-abstract - Saturated fats increasing atherogenicity of LDL-c https://pmc.ncbi.nlm.nih.gov/articles/PMC7416843/ - gut microbiome & CVD https://pmc.ncbi.nlm.nih.gov/articles/PMC7049528/ - high fibre diets on short chain fatty acids https://pmc.ncbi.nlm.nih.gov/articles/PMC7230435/ - Gut microbiome & intestinal permeability Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview Links to cardiac screening - North West, UK https://www.timcogleyfoundation.com https://healthchecks.randoxhealth.com/tim-cogley-foundation

41 min

16/12/2024

Interpreting Cardiovascular Biomarkers | ApoB | LDL-C | BMI | Metabolic Age | Fasting Glucose

Welcome back to our podcast, in this episode we discuss our recent cardiac screening results. Cardiovascular disease is still the biggest killer worldwide and so being able to interpret our blood results and calculating our individual risk is important in order to help prevent progression in the future. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:03 - Introduction 01:40 - LDL-C and its role in cardiovascular risk 02:14 - LDL-C: What our results were and what should we be aiming for? 02:50 - Why you shouldn’t use results in isolation | Area under the curve 04:00 - Significance of family history on cardiovascular disease risk 06:50 - Is ApoB a superior biomarker for measuring cardiovascular disease risk? 10:00 - Interpreting ApoB results | Should we be more aggressive in treating ApoB levels? 17:16 - Balancing health anxiety with being health conscious 18:53 - Interpretation of BMI | BMI limitations 24:52 - Where did we get our cardiac screening test done? | Tim Cogley Foundation 26:06 - Metabolic age v chronological age | How accurate is this test? 27:40 - Why we should know our own health on a deeper level 28:26 - Fasting blood glucose; our results 30:12 - Advocating prevention of long term health conditions, but emphasising the importance of pharmacological therapy when it is needed 33:55 - Cardiovascular risk score 38:05 - upcoming podcast episodes | Summary Here is our podcast links: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA https://podcasts.apple.com/us/podcast/the-chemist-couple-podcast/id1773332678 Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://pmc.ncbi.nlm.nih.gov/articles/PMC10693914/#:~:text=BMI%20was%20originally%20established%20in,benefits%20%5B1%2C2%5D - BMI review in clinical practice https://www.lipidcenter.com/pdf/Framingham.pdf - ApoB percentile chart https://pmc.ncbi.nlm.nih.gov/articles/PMC7369156/ - Overview of ApoB https://www.ahajournals.org/doi/10.1161/JAHA.122.025858 - ApoB physiology Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview Links to cardiac screening - North West, UK https://www.timcogleyfoundation.com https://healthchecks.randoxhealth.com/tim-cogley-foundation

39 min

09/12/2024

Best Exercises For Overall Health & Longevity

Welcome back to our podcast, in this episode we discuss how you should be exercising and we feel this very appropriate coming up to the New Year’s resolutions. We give our insight on what is working for us currently and debunk a lot of myths that people may be presented with when starting their exercise journey. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:03 - Introduction 00:38 - What did Jess used to do for exercise? 02:26 - Did HIIT training work for Jess? 03:00- What did Lee used to do for exercise? 05:08 - What training is working for Jess at the moment? 07:45 - Are current training regimens over complicated? 09:20 - Hyrox, get involved or get rid? 10:28- Should you focus on your weaknesses in exercise? 11:45 - 1% improvements will result in the greatest successes 12:47 - consistency is key 13:30 - Why do we exercise and why should you exercise? 16:30 - How should you start exercising? 19:04 - What is the evidence for exercise being of benefit? 20:32 - Find your purpose for exercising 21:58 - What are we going to implement in your training going forward? 25:40 - Final thoughts 28:52 - What is our next episode? Here is our podcast link: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://www.who.int/news-room/fact-sheets/detail/falls - falls stats from WHO 2021 https://assets.publishing.service.gov.uk/media/641d9957ba5ac9000cb1a838/CMOs-physical-activity-guidelines-appendices-march-2023.pdf - CMO UK’s activity guidelines https://www.amjmed.com/article/s0002-9343(14)00138-7/fulltext - muscle mass with longevity Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview

30 min

02/12/2024

Should Calories Count?

Welcome back to our podcast, in this episode we discuss if counting calories is helpful in achieving our health goals. We talk through both the benefits of counting calories but also the potential pitfalls of this popular ‘diet’. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:03 - Introduction 01:19 - What is a calorie? 02:01 - Food is more than just calories 02:42 - Why did Jess count calories? 04:05 - Where there more benefits for Jess counting calories? 06:08- Has calorie counting created a negative relationship with Jess’s food habits? 08:30 - What are the benefits to calorie counting? 10:16 - What are the negatives to calorie counting? 11:48 - Are calculated calories accurate? 15:15 - Do we count calories for health or aesthetics? 17:15 - Does calorie counting have longevity? 18:25 - Social media’s ‘healthy meal alternative’ trend 20:15 - What should you do if you currently count calories? 23:25 - Do you now look at food differently? 24:50 - How do you deal with not focussing on calories? 26:01 - What is our overall opinion on calorie counting? 30:25 - Can you bank calories? 32:05 - Summary Here is our podcast link: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://pmc.ncbi.nlm.nih.gov/articles/PMC3396444/#bib2 https://pmc.ncbi.nlm.nih.gov/articles/PMC7946062/ https://pmc.ncbi.nlm.nih.gov/articles/PMC3405064/ https://www.gov.uk/government/publications/calorie-labelling-in-the-out-of-home-sector/calorie-labelling-in-the-out-of-home-sector-implementation-guidance Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview

33 min

25/11/2024

Does Dietary Cholesterol Increase Cardiovascular Risk?

Welcome back to our podcast and to a question which many want a clear answer to, does dietary cholesterol increase cardio vascular risk? Honestly, the evidence is a hard read and we invite you to listen to our opinions and more importantly, how are we going to implement the studies. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:03 - Introduction 01:30 - Did you think dietary cholesterol increases serum levels? 02:43 - Why are eggs used in cholesterol studies? 03:55 - What are the current guidelines for cholesterol consumption? 05:00 - Does dietary cholesterol increase serum cholesterol? 09:16- How much dietary cholesterol do we absorb? 10:50 - Why do we have LDL cholesterol, an evolutionary trait? 13:24 - What foods are high in dietary cholesterol? 13:52 - Does saturated fat have a role to play in serum cholesterol? 17:50 - How do genetics play a part in serum cholesterol levels? 18:23 - Are we treating serum cholesterol appropriately? 19:09 - Does the gut microbiome play a role in serum cholesterol? 22:56 - What are we going to do with our diet? 27:32 - What to expect in upcoming podcasts Sign up to our newsletter: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://www.jacc.org/doi/10.1016/j.jacc.2020.05.077 https://pmc.ncbi.nlm.nih.gov/articles/PMC9143438/#sec2-nutrients-14-02168 https://www.jlr.org/article/S0022-2275(20)33370-8/fulltext https://www.ahajournals.org/doi/10.1161/CIR.0000000000000743 https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-019-0715-8#Sec25 https://pmc.ncbi.nlm.nih.gov/articles/PMC6024687/#notes2 https://www.cambridge.org/core/journals/nutrition-research-reviews/article/nutritional-management-of-hyperapob/FF922E54AB1189F1AF2194888D99DA0F https://www.jlr.org/article/S0022-2275(20)33152-7/fulltext Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview Randox link: https://www.timcogleyfoundation.com/cardiac-screening/

28 min

The Chemist Couple Podcast

Top 5 Health Trends for 2025

Stop Wasting Your Money on Vitamins

Should You Worry About rising Colon Cancer Rates in Younger People? | How To Improve Your Outcomes

How to Lower Your ApoB | Is the Gut Microbiome Involved in Cholesterol Metabolism?

Interpreting Cardiovascular Biomarkers | ApoB | LDL-C | BMI | Metabolic Age | Fasting Glucose

Best Exercises For Overall Health & Longevity

Should Calories Count?

Does Dietary Cholesterol Increase Cardiovascular Risk?

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The Chemist Couple Podcast

Episodes

Top 5 Health Trends for 2025

Stop Wasting Your Money on Vitamins

Should You Worry About rising Colon Cancer Rates in Younger People? | How To Improve Your Outcomes

How to Lower Your ApoB | Is the Gut Microbiome Involved in Cholesterol Metabolism?

Interpreting Cardiovascular Biomarkers | ApoB | LDL-C | BMI | Metabolic Age | Fasting Glucose

Best Exercises For Overall Health & Longevity

Should Calories Count?

Does Dietary Cholesterol Increase Cardiovascular Risk?

About

Information

You Might Also Like