54 min

189. Leslie Kenny on Overcoming Health Challenges, Gut Health, and the Benefits of Spermidine for Aging Better Executive Health and Life

    • Education

Defying diagnoses and aging gracefully are no small feats. But our guest, Leslie Kenny, not only accomplished these but has made it her life's work to inspire others to do the same.

Leslie was given a grim prognosis of a five-year life expectancy after her diagnosis of lupus in her 30s, but she managed to shatter those expectations and build a thriving life.

Now, in her work with Oxford Healthspan and the Oxford Longevity Project, she emphasizes the importance of immune system rebalancing along with precise dietary and lifestyle changes.

The conversation takes an intriguing turn when we tackle the subject of gut health and its paramount role in our well-being. From exploring the link between leaky gut and autoimmune conditions to shedding light on the 12 hallmarks of aging, we take you on a journey through the complexities of the human body. We also delve into the process of autophagy and the role that fasting plays in fostering healthier cells.

We also take a deep dive into our discussion about autophagy, fasting, and the critical role of polyamines in the body. And if you've ever wondered about the benefits of spermidine supplementation, you're in for quite the treat (mind-blowing benefits).

We'll also explore the importance of muscle as a longevity currency and the risks of becoming too lean. Finally, we discuss the impact of intense exercise on hair loss, provide strategies to mitigate the effects of stress hormones, and offer practical tips to help you become the CEO of your health. Tune in for an enlightening conversation that is sure to level up your understanding of health, aging, and longevity.

— Episode Chapter Big Ideas (timing may not be exact) —

(0:00:02) - Defying Diagnoses and Aging Gracefully

(0:10:10) - Leaky Gut and Aging Hallmarks

(0:14:25) - Hallmarks of Aging and Autophagy

(0:21:41) - Autophagy, Fasting, and Polyamines

(0:31:09) - Polyamines and Spermidine in Aging

(0:40:14) - The Benefits of Spermidine Supplementation

(0:52:51) - Gym Rats and Facial Hair Stress

— Connect with Leslie —

Website — https://oxfordhealthspan.com/

Instagram (Oxford Healthspan) — https://www.instagram.com/oxfordhealthspan/

Instagram (Leslie's) — https://www.instagram.com/lesliesnewprime/

Instagram (Oxford Longevity Project) — https://www.instagram.com/oxfordlongevityproject/

LinkedIn (Oxford Healthspan) — https://www.linkedin.com/company/68855978

LinkedIn (Oxford Longevity Project) —https://www.linkedin.com/company/oxford-longevity-project/

LinkedIn (Leslie Kenny) — https://www.linkedin.com/in/leslie-k-28435a/

— A Special Gift and Thank You to Leslie & Oxford Healthspan —

Spermidine improves healthspan by inhibiting 9 of the 12 hallmarks of aging and benefiting the areas of beauty and sleep. If interested in adding high-quality Spermidine to your regimen, there's a code below to save.

Primeadine: Use promo code JULIAN15 to save 15% off your first purchase at https://oxfordhealthspan.com/products/primeadine-spermidine-supplement-30-day-supply

— Connect with Julian and Executive Health —

Curious about becoming a concierge client? Sign up for a complimentary 60-minute Executive Performance Consult — ⁠⁠executivehealth.io/contact⁠⁠

LinkedIn — ⁠⁠https://www.linkedin.com/in/julianhayesii/⁠⁠

Join the 'Enhanced Executive Journal' + get our free executive health report: ‘The Optimal Executive: 17 Impactful Actions to Look, Feel, and Stay at The Top of Your Game.' Visit— ⁠⁠executivehealth.io/report⁠⁠

***DISCLAIMER The information shared is not meant to treat or diagnose any condition. This is for educational, informational, and entertainment purposes. The content here is not intended to replace your relationship with your doctor and/or medical practitioner. Any decision to begin the use of the following supplements or use any of the information on this website or podcast should be discussed with your doctor and/or medical practitioner.


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Defying diagnoses and aging gracefully are no small feats. But our guest, Leslie Kenny, not only accomplished these but has made it her life's work to inspire others to do the same.

Leslie was given a grim prognosis of a five-year life expectancy after her diagnosis of lupus in her 30s, but she managed to shatter those expectations and build a thriving life.

Now, in her work with Oxford Healthspan and the Oxford Longevity Project, she emphasizes the importance of immune system rebalancing along with precise dietary and lifestyle changes.

The conversation takes an intriguing turn when we tackle the subject of gut health and its paramount role in our well-being. From exploring the link between leaky gut and autoimmune conditions to shedding light on the 12 hallmarks of aging, we take you on a journey through the complexities of the human body. We also delve into the process of autophagy and the role that fasting plays in fostering healthier cells.

We also take a deep dive into our discussion about autophagy, fasting, and the critical role of polyamines in the body. And if you've ever wondered about the benefits of spermidine supplementation, you're in for quite the treat (mind-blowing benefits).

We'll also explore the importance of muscle as a longevity currency and the risks of becoming too lean. Finally, we discuss the impact of intense exercise on hair loss, provide strategies to mitigate the effects of stress hormones, and offer practical tips to help you become the CEO of your health. Tune in for an enlightening conversation that is sure to level up your understanding of health, aging, and longevity.

— Episode Chapter Big Ideas (timing may not be exact) —

(0:00:02) - Defying Diagnoses and Aging Gracefully

(0:10:10) - Leaky Gut and Aging Hallmarks

(0:14:25) - Hallmarks of Aging and Autophagy

(0:21:41) - Autophagy, Fasting, and Polyamines

(0:31:09) - Polyamines and Spermidine in Aging

(0:40:14) - The Benefits of Spermidine Supplementation

(0:52:51) - Gym Rats and Facial Hair Stress

— Connect with Leslie —

Website — https://oxfordhealthspan.com/

Instagram (Oxford Healthspan) — https://www.instagram.com/oxfordhealthspan/

Instagram (Leslie's) — https://www.instagram.com/lesliesnewprime/

Instagram (Oxford Longevity Project) — https://www.instagram.com/oxfordlongevityproject/

LinkedIn (Oxford Healthspan) — https://www.linkedin.com/company/68855978

LinkedIn (Oxford Longevity Project) —https://www.linkedin.com/company/oxford-longevity-project/

LinkedIn (Leslie Kenny) — https://www.linkedin.com/in/leslie-k-28435a/

— A Special Gift and Thank You to Leslie & Oxford Healthspan —

Spermidine improves healthspan by inhibiting 9 of the 12 hallmarks of aging and benefiting the areas of beauty and sleep. If interested in adding high-quality Spermidine to your regimen, there's a code below to save.

Primeadine: Use promo code JULIAN15 to save 15% off your first purchase at https://oxfordhealthspan.com/products/primeadine-spermidine-supplement-30-day-supply

— Connect with Julian and Executive Health —

Curious about becoming a concierge client? Sign up for a complimentary 60-minute Executive Performance Consult — ⁠⁠executivehealth.io/contact⁠⁠

LinkedIn — ⁠⁠https://www.linkedin.com/in/julianhayesii/⁠⁠

Join the 'Enhanced Executive Journal' + get our free executive health report: ‘The Optimal Executive: 17 Impactful Actions to Look, Feel, and Stay at The Top of Your Game.' Visit— ⁠⁠executivehealth.io/report⁠⁠

***DISCLAIMER The information shared is not meant to treat or diagnose any condition. This is for educational, informational, and entertainment purposes. The content here is not intended to replace your relationship with your doctor and/or medical practitioner. Any decision to begin the use of the following supplements or use any of the information on this website or podcast should be discussed with your doctor and/or medical practitioner.


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54 min

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