58 min

#11 Dr. Brian Kennedy | Aging Networks & Biomarkers, AKG, Spermidine and Longevity of Bats Live Longer World

    • Science

My guest today is Dr. Brian Kennedy who is the Director for the Center of Healthy Aging at the National University of Singapore. He is also the former President and CEO of the Buck Institute of Research on Aging. Dr. Kennedy is well-known in the field of longevity & beyond and has been involved in critical aging research.  Dr. Kennedy's lab is working on different small molecules and natural products that could boost longevity. 

In today's discussion, we spoke about the network concept of the hallmarks of aging, the longevity effects of natural products like Alpha-Ketoglutarate (AKG), Spermidine and Urolithin A, and why combining some of these supplements might not be prudent. We also spoke about comparing the different biomarkers of aging, what we can learn from the longevity of bats, and why basic science is important.  

All platforms / Episode Show Notes + Timestamps: https://livelongerworld.substack.com/p/bkennedy 

Sign up for Premium Subscriber Extensive Show Notes & Transcripts: https://www.livelongerworld.com/premium 

Find the previous podcast episodes & subscribe to be notified: https://www.livelongerworld.com/podcast 

Support on Patreon: https://www.patreon.com/livelongerworld 

DR. BRIAN KENNEDY LINKS: 

Lab Website: https://medicine.nus.edu.sg/bch/faculty/brian-kennedy/

Twitter: https://twitter.com/BKennedy_aging 

LIVE LONGER WORLD LINKS: 

Website: https://www.livelongerworld.com/

Twitter: https://twitter.com/livelongerworld

Newsletter: https://livelongerworld.substack.com/

Instagram: https://www.instagram.com/longevityfuture/

Patreon page: https://www.patreon.com/livelongerworld

Podcast All Platforms: https://anchor.fm/livelongerworld

YouTube: https://www.youtube.com/c/LiveLongerWorld

Apple Podcasts: https://apple.co/3eZAoAp

Spotify: https://spoti.fi/3eZB6O5

Google Podcasts: https://bit.ly/3HN0keG

Premium Subscriber Benefits: https://www.livelongerworld.com/premium 

DR. BRIAN KENNEDY RESEARCH DISCUSSED: 

2020 Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice: https://pubmed.ncbi.nlm.nih.gov/32877690/ 

2020 Aging Biomarkers: From Functional Tests to Multi-Omics Approaches: https://pubmed.ncbi.nlm.nih.gov/32084299/ 

2021 The Autophagy Inducer Spermidine Protects Against Metabolic Dysfunction During Overnutrition: https://pubmed.ncbi.nlm.nih.gov/34060628/ 

2021 Association between housing type and accelerated biological aging in different sexes: moderating effects of health behaviors: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436907/ 

2020 The World Goes Bats: Living & Tolerating Viruses: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341951/ 

2021 Yeast as a model organism for aging research: https://www.sciencedirect.com/science/article/pii/B9780128159620000081

Thanks for watching & if you enjoy the episode, please like, comment, subscribe & share!  Stay in good health - Aastha.

My guest today is Dr. Brian Kennedy who is the Director for the Center of Healthy Aging at the National University of Singapore. He is also the former President and CEO of the Buck Institute of Research on Aging. Dr. Kennedy is well-known in the field of longevity & beyond and has been involved in critical aging research.  Dr. Kennedy's lab is working on different small molecules and natural products that could boost longevity. 

In today's discussion, we spoke about the network concept of the hallmarks of aging, the longevity effects of natural products like Alpha-Ketoglutarate (AKG), Spermidine and Urolithin A, and why combining some of these supplements might not be prudent. We also spoke about comparing the different biomarkers of aging, what we can learn from the longevity of bats, and why basic science is important.  

All platforms / Episode Show Notes + Timestamps: https://livelongerworld.substack.com/p/bkennedy 

Sign up for Premium Subscriber Extensive Show Notes & Transcripts: https://www.livelongerworld.com/premium 

Find the previous podcast episodes & subscribe to be notified: https://www.livelongerworld.com/podcast 

Support on Patreon: https://www.patreon.com/livelongerworld 

DR. BRIAN KENNEDY LINKS: 

Lab Website: https://medicine.nus.edu.sg/bch/faculty/brian-kennedy/

Twitter: https://twitter.com/BKennedy_aging 

LIVE LONGER WORLD LINKS: 

Website: https://www.livelongerworld.com/

Twitter: https://twitter.com/livelongerworld

Newsletter: https://livelongerworld.substack.com/

Instagram: https://www.instagram.com/longevityfuture/

Patreon page: https://www.patreon.com/livelongerworld

Podcast All Platforms: https://anchor.fm/livelongerworld

YouTube: https://www.youtube.com/c/LiveLongerWorld

Apple Podcasts: https://apple.co/3eZAoAp

Spotify: https://spoti.fi/3eZB6O5

Google Podcasts: https://bit.ly/3HN0keG

Premium Subscriber Benefits: https://www.livelongerworld.com/premium 

DR. BRIAN KENNEDY RESEARCH DISCUSSED: 

2020 Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice: https://pubmed.ncbi.nlm.nih.gov/32877690/ 

2020 Aging Biomarkers: From Functional Tests to Multi-Omics Approaches: https://pubmed.ncbi.nlm.nih.gov/32084299/ 

2021 The Autophagy Inducer Spermidine Protects Against Metabolic Dysfunction During Overnutrition: https://pubmed.ncbi.nlm.nih.gov/34060628/ 

2021 Association between housing type and accelerated biological aging in different sexes: moderating effects of health behaviors: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436907/ 

2020 The World Goes Bats: Living & Tolerating Viruses: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341951/ 

2021 Yeast as a model organism for aging research: https://www.sciencedirect.com/science/article/pii/B9780128159620000081

Thanks for watching & if you enjoy the episode, please like, comment, subscribe & share!  Stay in good health - Aastha.

58 min

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