The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)

Sam Charrington
The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)

Machine learning and artificial intelligence are dramatically changing the way businesses operate and people live. The TWIML AI Podcast brings the top minds and ideas from the world of ML and AI to a broad and influential community of ML/AI researchers, data scientists, engineers and tech-savvy business and IT leaders. Hosted by Sam Charrington, a sought after industry analyst, speaker, commentator and thought leader. Technologies covered include machine learning, artificial intelligence, deep learning, natural language processing, neural networks, analytics, computer science, data science and more.

  1. 3 DAYS AGO

    AI Trends 2025: AI Agents and Multi-Agent Systems with Victor Dibia

    Today we’re joined by Victor Dibia, principal research software engineer at Microsoft Research, to explore the key trends and advancements in AI agents and multi-agent systems shaping 2025 and beyond. In this episode, we discuss the unique abilities that set AI agents apart from traditional software systems–reasoning, acting, communicating, and adapting. We also examine the rise of agentic foundation models, the emergence of interface agents like Claude with Computer Use and OpenAI Operator, the shift from simple task chains to complex workflows, and the growing range of enterprise use cases. Victor shares insights into emerging design patterns for autonomous multi-agent systems, including graph and message-driven architectures, the advantages of the “actor model” pattern as implemented in Microsoft’s AutoGen, and guidance on how users should approach the ”build vs. buy” decision when working with AI agent frameworks. We also address the challenges of evaluating end-to-end agent performance, the complexities of benchmarking agentic systems, and the implications of our reliance on LLMs as judges. Finally, we look ahead to the future of AI agents in 2025 and beyond, discuss emerging HCI challenges, their potential for impact on the workforce, and how they are poised to reshape fields like software engineering. The complete show notes for this episode can be found at https://twimlai.com/go/718.

    1h 45m

  2. FEB 4

    Speculative Decoding and Efficient LLM Inference with Chris Lott

    Today, we're joined by Chris Lott, senior director of engineering at Qualcomm AI Research to discuss accelerating large language model inference. We explore the challenges presented by the LLM encoding and decoding (aka generation) and how these interact with various hardware constraints such as FLOPS, memory footprint and memory bandwidth to limit key inference metrics such as time-to-first-token, tokens per second, and tokens per joule. We then dig into a variety of techniques that can be used to accelerate inference such as KV compression, quantization, pruning, speculative decoding, and leveraging small language models (SLMs). We also discuss future directions for enabling on-device agentic experiences such as parallel generation and software tools like Qualcomm AI Orchestrator. The complete show notes for this episode can be found at https://twimlai.com/go/717.

    1h 17m

  3. JAN 28

    Ensuring Privacy for Any LLM with Patricia Thaine

    Today, we're joined by Patricia Thaine, co-founder and CEO of Private AI to discuss techniques for ensuring privacy, data minimization, and compliance when using 3rd-party large language models (LLMs) and other AI services. We explore the risks of data leakage from LLMs and embeddings, the complexities of identifying and redacting personal information across various data flows, and the approach Private AI has taken to mitigate these risks. We also dig into the challenges of entity recognition in multimodal systems including OCR files, documents, images, and audio, and the importance of data quality and model accuracy. Additionally, Patricia shares insights on the limitations of data anonymization, the benefits of balancing real-world and synthetic data in model training and development, and the relationship between privacy and bias in AI. Finally, we touch on the evolving landscape of AI regulations like GDPR, CPRA, and the EU AI Act, and the future of privacy in artificial intelligence. The complete show notes for this episode can be found at https://twimlai.com/go/716.

    52 min

  4. JAN 21

    AI Engineering Pitfalls with Chip Huyen

    Today, we're joined by Chip Huyen, independent researcher and writer to discuss her new book, “AI Engineering.” We dig into the definition of AI engineering, its key differences from traditional machine learning engineering, the common pitfalls encountered in engineering AI systems, and strategies to overcome them. We also explore how Chip defines AI agents, their current limitations and capabilities, and the critical role of effective planning and tool utilization in these systems. Additionally, Chip shares insights on the importance of evaluation in AI systems, highlighting the need for systematic processes, human oversight, and rigorous metrics and benchmarks. Finally, we touch on the impact of open-source models, the potential of synthetic data, and Chip’s predictions for the year ahead. The complete show notes for this episode can be found at https://twimlai.com/go/715.

    58 min

  5. JAN 13

    Evolving MLOps Platforms for Generative AI and Agents with Abhijit Bose

    Today, we're joined by Abhijit Bose, head of enterprise AI and ML platforms at Capital One to discuss the evolution of the company’s approach and insights on Generative AI and platform best practices. In this episode, we dig into the company’s platform-centric approach to AI, and how they’ve been evolving their existing MLOps and data platforms to support the new challenges and opportunities presented by generative AI workloads and AI agents. We explore their use of cloud-based infrastructure—in this case on AWS—to provide a foundation upon which they then layer open-source and proprietary services and tools. We cover their use of Llama 3 and open-weight models, their approach to fine-tuning, their observability tooling for Gen AI applications, their use of inference optimization techniques like quantization, and more. Finally, Abhijit shares the future of agentic workflows in the enterprise, the application of OpenAI o1-style reasoning in models, and the new roles and skillsets required in the evolving GenAI landscape. The complete show notes for this episode can be found at https://twimlai.com/go/714.

    58 min

  6. 12/16/2024

    Why Agents Are Stupid & What We Can Do About It with Dan Jeffries

    Today, we're joined by Dan Jeffries, founder and CEO of Kentauros AI to discuss the challenges currently faced by those developing advanced AI agents. We dig into how Dan defines agents and distinguishes them from other similar uses of LLM, explore various use cases for them, and dig into ways to create smarter agentic systems. Dan shared his “big brain, little brain, tool brain” approach to tackling real-world challenges in agents, the trade-offs in leveraging general-purpose vs. task-specific models, and his take on LLM reasoning. We also cover the way he thinks about model selection for agents, along with the need for new tools and platforms for deploying them. Finally, Dan emphasizes the importance of open source in advancing AI, shares the new products they’re working on, and explores the future directions in the agentic era. The complete show notes for this episode can be found at https://twimlai.com/go/713.

    1h 9m

  7. 12/09/2024

    Automated Reasoning to Prevent LLM Hallucination with Byron Cook

    Today, we're joined by Byron Cook, VP and distinguished scientist in the Automated Reasoning Group at AWS to dig into the underlying technology behind the newly announced Automated Reasoning Checks feature of Amazon Bedrock Guardrails. Automated Reasoning Checks uses mathematical proofs to help LLM users safeguard against hallucinations. We explore recent advancements in the field of automated reasoning, as well as some of the ways it is applied broadly, as well as across AWS, where it is used to enhance security, cryptography, virtualization, and more. We discuss how the new feature helps users to generate, refine, validate, and formalize policies, and how those policies can be deployed alongside LLM applications to ensure the accuracy of generated text. Finally, Byron also shares the benchmarks they’ve applied, the use of techniques like ‘constrained coding’ and ‘backtracking,’ and the future co-evolution of automated reasoning and generative AI. The complete show notes for this episode can be found at https://twimlai.com/go/712.

    57 min

  8. 12/03/2024

    AI at the Edge: Qualcomm AI Research at NeurIPS 2024 with Arash Behboodi

    Today, we're joined by Arash Behboodi, director of engineering at Qualcomm AI Research to discuss the papers and workshops Qualcomm will be presenting at this year’s NeurIPS conference. We dig into the challenges and opportunities presented by differentiable simulation in wireless systems, the sciences, and beyond. We also explore recent work that ties conformal prediction to information theory, yielding a novel approach to incorporating uncertainty quantification directly into machine learning models. Finally, we review several papers enabling the efficient use of LoRA (Low-Rank Adaptation) on mobile devices (Hollowed Net, ShiRA, FouRA). Arash also previews the demos Qualcomm will be hosting at NeurIPS, including new video editing diffusion and 3D content generation models running on-device, Qualcomm's AI Hub, and more! The complete show notes for this episode can be found at https://twimlai.com/go/711.

    55 min
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About

Machine learning and artificial intelligence are dramatically changing the way businesses operate and people live. The TWIML AI Podcast brings the top minds and ideas from the world of ML and AI to a broad and influential community of ML/AI researchers, data scientists, engineers and tech-savvy business and IT leaders. Hosted by Sam Charrington, a sought after industry analyst, speaker, commentator and thought leader. Technologies covered include machine learning, artificial intelligence, deep learning, natural language processing, neural networks, analytics, computer science, data science and more.

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