Px Pulse

Px Pulse
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Px Pulse

Px Pulse explores vital topics confronting the field of HIV prevention research. Our monthly podcast will deepen your knowledge and help you “check the pulse” of this fast-paced field and the urgent challenges still ahead. Tune in for interviews, first-person accounts and robust discussion from advocates, researchers, policy-makers and community stakeholders as they take on critical issues facing HIV prevention research today.

  1. The Votes Are In: What’s next for the US’ role in global health and HIV prevention? KFF’s Jen Kates and AVAC’s Suraj Madoori lay out the challenges and the priorities in 2025 and beyond.  

    قبل ٦ أيام

    The Votes Are In: What’s next for the US’ role in global health and HIV prevention? KFF’s Jen Kates and AVAC’s Suraj Madoori lay out the challenges and the priorities in 2025 and beyond.  

    In the days and years ahead under a Trump Administration, advocacy for choice, freedom, science, and rights will require deep strategic shifts to protect hard-fought gains in global health generally, and to safeguard policies and programs that advance it. And there will be major implications for the global AIDS response. Joining us to navigate all this and to better understand the landscape for advocacy are Jen Kates from KFF, a nonpartisan health policy research organization, and our own Suraj Madoori.

    ٢١ من الدقائق
  2. PxPulse: The Advocacy Chronicles with Danielle Campbell from PrEP in Black America

    ٢١ ربيع الآخر

    PxPulse: The Advocacy Chronicles with Danielle Campbell from PrEP in Black America

    In this episode of the Advocacy Chronicles, we put the spotlight on the US, on the dismal statistics on access to PrEP in Black communities, on the state of HIV prevention among Black Americans overall, and the work of one advocacy group—PrEP in Black America (PIBA). Danielle Campbell is one of the founders of PIBA and a long-time advocate for HIV prevention and health equity. She joins the Advocacy Chronicles to talk about PIBA’s call to action for an HIV research agenda that prioritizes the needs of Black communities.

    ١٥ من الدقائق
  3. Lenacapavir: The case for investing in delivering HIV prevention

    ١٦ ربيع الأول

    Lenacapavir: The case for investing in delivering HIV prevention

    The promise of long-acting PrEP has been super-charged this year by studies showing the powerful efficacy of an antiretroviral known as lenacapavir (LEN).  This episode of PxPulse goes deep on LEN for PrEP. Recorded just days before Gilead’s announcement that PURPOSE 2 also found very high efficacy, Dr. Flavia Kiweewa, a principal investigator of PURPOSE 1, the first trial to announce efficacy, lays out the research findings and what they mean. And Chilufya Kasanda Hampongo of Zambia’s Treatment Advocacy and Literacy Campaign and Mitchell Warren of AVAC talk about how to change a long history of squandered opportunities to get rollout right.  The PURPOSE1 trials announced findings in June that a twice-yearly injection of LEN was 100% effective among cisgender women, with zero new cases of HIV. And the PURPOSE 2 trial among cisgender men, and trans and non-binary people, was shown to reduce the risk of HIV by 96%.  LEN now enters a select category, one of five ARV-based options for PrEP that all protect against HIV if you take them.  But many of the people applauding the results from PURPOSE 1 and 2 will tell you that breakthrough science like this is, as hard as it is, is still the easy part. To break the back of the HIV epidemic demands overcoming an altogether different challenge—coordinating and accelerating every step in rolling out new products so that everyone who needs HIV prevention can get it.    Listen to this podcast to learn what must be done to finally deliver on the promise of highly effective HIV prevention, from pills to rings to injectable PrEP and beyond.   Resources  Second Pivotal Trial of Twice-Yearly HIV Prevention Injection Safe and Highly Effective: PURPOSE 2 Trial Among Gay Men, Trans and Nonbinary People, AVAC Press Release  The Lens on LEN: The basics on injectable lenacapavir as PrEP, AVAC  Country planning matrix, PrEPWatch  Moving a Product to the Real World, AVAC  The long wait for long-acting HIV prevention and treatment formulations, Lancet  A game-changer for PrEP if access is adequate, Lancet  Allocation of Non-Commercial CAB for PrEP Supply in Low- and Middle-Income Countries, 2023-2025, AVAC  Generic Cabotegravir Timelines, AVAC  UNAIDS Exec Summary, UNAIDS  Lenacapavir: What it would it take to get the 6-monthly anti-HIV jab to SA, Bhekisisa

    ٣٢ من الدقائق
  4. An Advocacy Chronicle on U=U in SA with Mandisa Dukashe

    ٢٥ صفر

    An Advocacy Chronicle on U=U in SA with Mandisa Dukashe

    A list of tactics proved critical; establishing a dedicated working group that brought in diverse expertise and support; ensuring there were educated and committed policy leaders in government; and supporting community members to be ready to lead. Additional Resources to inform your advocacy: 1. Implementing and Scaling Up U=U: A Resource Guide chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://jasem.chiachoob.com/global-hiv-tb/media/pdfs/2024/07/U-U-Resource-Guide-July-12-2024.pdf 2. Treatment saves lives, and prevents HIV transmission https://avac.org/prevention-option/treatment/ 3. HIV Testing for Advocates https://avac.org/resource/hiv-testing-for-advocates/ 4. Prevention Access Campaign https://preventionaccess.com/ 5. WHO guidance on HIV viral suppression and scientific updates released at IAS 2023 https://www.who.int/news/item/23-07-2023-new-who-guidance-on-hiv-viral-suppression-and-scientific-updates-released-at-ias-2023

    ١٢ من الدقائق
  5. The Advocacy Chronicles with Ruth Akulu

    ١٢ محرم

    The Advocacy Chronicles with Ruth Akulu

    On this episode of the Advocacy Chronicles:  A look at advocacy in Uganda for the Dual Prevention Pill (DPP), a new product combining oral PrEP and oral contraception. Ruth Akulu is a member of the DPP Civil Society Advisory Group, part of the Uganda Country Coordinating Mechanism Board for Global Fund,  and a 2022 AVAC Advocacy Fellow. Akulu talks about her work to mobilize regulatory authorities to prepare for the DPP. And while she was at it, the establishment of a groundbreaking new initiative, the Product Regulator’s Engagement Committee, which is supporting ongoing engagement between government regulators and young women representing their communities.  To support your advocacy for the DPP and other multipurpose prevention technologies check out AVAC's Advocates' Guide on MPTs  https://avac.org/resource/advocates-guide-to-multipurpose-prevention-technologies-mpts/ ]

    ١١ من الدقائق
  6. PxPulse: The Advocacy Chronicles with SMUG’s Allan Mwasa

    ٢٩ ذو القعدة

    PxPulse: The Advocacy Chronicles with SMUG’s Allan Mwasa

    In this episode,  Nsubuga Allan Mwasa a Ugandan activist, a clinical psychologist,  and a representative of Sexual Minorities Uganda, or SMUG, an organization that has been at the forefront of the fight for LGBTQ rights, talks about how advocates are organizing to survive and challenge Uganda's Anti-Homosexuality Act (AHA), passed one year ago.  A donation to SMUG supports the work of the Strategic Response Team documenting civil rights violations and intensifying persecution of LGBTQI+ Ugandans. Funds have reached a critical low,  click here to donate to SMUG.    SMUG is part of Convening For Equality CFE, a coalition of civil society groups dedicated to challenging Uganda's AHA and other legislation that discriminates against LGBTQI+ individuals. The law has significantly increased discrimination and violence against the LGBTQI+ community, despite widespread international condemnation and ongoing legal challenges. A new report by the CFE's Strategic Response Team (SRT), UNWANTED, OUTLAWED AND ILLEGAL: THE CRY OF LGBTIQ+ UGANDANS, documents evictions, arrests, imprisonment, forced anal examaminations, and community violence against LGBTQ+ people since the passage of AHA.

    ١٦ من الدقائق
  7. An HIV Vaccine: Looking into the future with Nina Russell

    ٥ ذو القعدة

    An HIV Vaccine: Looking into the future with Nina Russell

    It’s considered one of the most important and most difficult scientific enterprises in the history of modern medicine—the hunt for an HIV vaccine.  It has led to vast knowledge of HIV and the immune system, and to breakthrough technology. But developing an effective HIV vaccine is still out of reach, while HIV incidence remains high in hard-hit places in the world. In this episode, Nina Russell of the Bill & Melinda Gates Foundation talks about where she sees promise in the science, the goals for an HIV vaccine, and why it has an essential role to play alongside the scale-up of PrEP. Go to https://avac.org/resource/an-hiv-vaccine/

    ١٦ من الدقائق
  8. PxPulse: The Advocacy Chronicles with APHA’s Yvette Raphael

    ٧ شوال

    PxPulse: The Advocacy Chronicles with APHA’s Yvette Raphael

    Our debut episode of the Advocacy Chronicles features Yvette Raphael, the Executive Director of Advocacy for Prevention of HIV and AIDS (APHA) in South Africa, and a leader in the development of The Choice Manifesto, supported from start to finish by CASPR. As co-chair of the African Women Prevention Community Accountability Board (AWPCAB), Yvette and other board members launched the manifesto in Kampala, in September 2023, calling for choice in HIV prevention options for women — such as oral and injectable cabotegravir for PrEP, the dapivirine vaginal ring and the Dual Prevention Pill — and a commitment to expanding access to them. A call heard by UNAIDS Executive Director Winnie Byanyima, who was on hand at the launch to endorse the manifesto.   Yvette, who is also a 2014 AVAC Advocacy Fellow and celebrated as one of South Africa’s leading human rights activists, lays out why The Choice Manifesto matters and how advocates are leveraging it.

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Px Pulse explores vital topics confronting the field of HIV prevention research. Our monthly podcast will deepen your knowledge and help you “check the pulse” of this fast-paced field and the urgent challenges still ahead. Tune in for interviews, first-person accounts and robust discussion from advocates, researchers, policy-makers and community stakeholders as they take on critical issues facing HIV prevention research today.

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