291 episodes

The world of medicine can be challenging. Clinicians and patients are always looking for more options, more effective treatments… and in the end, more answers. What if there was a way to practice medicine that digs deeper and offers a new perspective? Functional medicine focuses on addressing root causes of disease. At Genova Diagnostics we’ve watched this field evolve and grow for over 35 years….

We’ve not only adapted, we’ve led. Join us as we talk about functional medicine, laboratory testing, and optimizing health. Welcome to the Lab Report.

The Lab Report Genova Diagnostics, Inc

    • Health & Fitness
    • 4.7 • 106 Ratings

The world of medicine can be challenging. Clinicians and patients are always looking for more options, more effective treatments… and in the end, more answers. What if there was a way to practice medicine that digs deeper and offers a new perspective? Functional medicine focuses on addressing root causes of disease. At Genova Diagnostics we’ve watched this field evolve and grow for over 35 years….

We’ve not only adapted, we’ve led. Join us as we talk about functional medicine, laboratory testing, and optimizing health. Welcome to the Lab Report.

    The Methylation Cycle: Deep Cuts

    The Methylation Cycle: Deep Cuts

    Methylation is a very important enzymatic reaction responsible for so many crucial metabolic processes. In a previous episode, we introduced the topic of methylation and the basics of this biochemical reaction.  However, there are many subtle nuances to consider when assessing whether a patient’s methylation cycle is out of balance.

    Today, we dive a bit deeper into the biochemistry of methylation and peel back the layers to show how some of the specific biomarkers and backup pathways contribute to imbalance. And, what does that mean clinically? It may help to review our prior episode or use Genova’s Methylation Pathway Handout to follow along.

    Today on The Lab Report:


    2:50 Quick review of the methylation cycle
    4:45 The important relationship between choline and betaine
    7:05 Logical Speculation: Why is the betaine: choline ratio associated with disease risk?
    9:35 Dimethylglycine (DMG)
    11:15 Sarcosine and the ‘SAM disposal chute’
    14:20 Glycine: What does it do?
    16:55 Transsulfuration and glutathione
    21:00 The multi-omics of the methylation panel
    22:25 Question of the Day:  What is the stability of measuring SAM and SAH?

    Additional Resources:

    Genova's Methylation Panel

    Dr. Michael Chapman's Methylation Webinar

    Genova Connect  **PROMO CODE TheLabReport for 20% off your purchase**

    Subscribe, Rate, & Review The Lab Report

    Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

    Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net.

    And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

    To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

    Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
    See omnystudio.com/listener for privacy information.

    • 26 min
    Metabolic Health = GOOD ENERGY with Dr. Casey Means

    Metabolic Health = GOOD ENERGY with Dr. Casey Means

    We are honored to welcome Dr. Casey Means back to the show. She is not only a passionate advocate for metabolic health, but also a voice of reason amidst a broken healthcare system, a profound champion spreading the message of connectedness and fearlessness, and lastly a dear friend. Dr. Means’ new book “Good Energy – The Surprising Connection Between Metabolism and Limitless Health” is available now anywhere books are sold.

    In this episode, we talk to Dr. Casey Means about her new book “Good Energy” which outlines how to connect the dots in healthcare, the critical importance of metabolic health, and practical tips to change your life and create your own GOOD ENERGY.

    Today on The Lab Report:


    3:10 The Amazing Dr. Casey Means on connection vs. siloes in medicine
    8:45 Economics of the current healthcare model and outdated thinking
    12:15 Longevity and biohacking – where have we lost our way?
    19:55 Fear of death, control, and transcending the fear mindset
    23:20 Fixing incentive structures of the healthcare system & food and farm industries
    33:10 Practical tips and eating for GOOD ENERGY
    40:55 Overcoming behavior change obstacles – listen to your body!
    44:00 ROI in eating healthy whole foods
    45:35 Life is miraculous, live in awe- not fear
    48:05 The Fireball

    Additional Resources:

    Get your copy of Good Energy today!

    Casey’s Newsletter sign-up: https://www.caseymeans.com/newsletter

    Casey’s Social Media Platforms:

    Instagram: https://www.instagram.com/drcaseyskitchen/

    Twitter: https://twitter.com/CaseyMeansMD

    TikTok: https://www.tiktok.com/@caseymeansmd

    YouTube: https://www.youtube.com/@CaseyMeansMD

    LinkedIn: https://www.linkedin.com/in/casey-means-md/

     

    Subscribe, Rate, & Review The Lab Report

    Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

    Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net.

    And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

    To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

    Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
    See omnystudio.com/listener for privacy information.

    • 52 min
    The Methylation Episode!

    The Methylation Episode!

    The word ‘methylation’ has become somewhat of a buzz word in functional and personalized medicine. We’ve mentioned it several times throughout many episodes of The Lab Report – hard to avoid since it’s involved in just about every biological process.

    In today’s episode, we finally hit the topic of methylation head on and dive into the methylation cycle itself. What is it? Why should you care? Although biochemistry can be intimidating, listen as we simplify and demystify the steps involved. You may find it helpful to refer to a Methylation Pathway Chart while listening to this one!

     

    Today on The Lab Report:


    2:00 What is methylation and why is it clinically important
    5:30 Jumping into the biochemistry – metaphors to the rescue!
    11:35 Homocysteine
    14:00 The main pathway versus back up pathway
    19:33 Transsulfuration
    22:30 Multi-omics and the methylation cycle
    27:50 Question of the Day

    “What does it mean if homocysteine is low?”



     

    Additional Resources:

    Genova's Methylation Panel

    Dr. Michael Chapman's Methylation Webinar

    Genova Connect  **PROMO CODE TheLabReport20 for 20% off your purchase**

     

    Subscribe, Rate, & Review The Lab Report

    Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

    Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net.

    And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

    To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

    Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
    See omnystudio.com/listener for privacy information.

    • 32 min
    Holistic Mental Health with Everest Goldstein

    Holistic Mental Health with Everest Goldstein

    Everest Goldstein is a board-certified Psychiatric Nurse Practitioner who is also certified in Functional Medicine and has an extensive background in integrative wellness interventions. She deeply cares about her patients and devotes her time to working closely with each of them to address their individual needs. Knowing the importance of the brain-body connection, Everest addresses the body as a whole to optimize health and wellness.

    In today’s episode, we dive into the root causes of mood disorders and psychiatric illness with Everest Goldstein. Everest discusses how nutrition, diet, and lifestyle can contribute to mental health and wellness. If you are struggling mentally, emotionally, or physically, Everest is here to help you regain your life.

    Today on The Lab Report:


    4:30 Meet Everest Goldstein and hear about her passion for psychiatry
    7:45 Everest’s unique approach to mental health
    9:55 The debate of mental health root causes
    12:15 Gut microbiome and the brain connection
    16:50 Nutrition changes for better outcomes
    20:00 Using the ketogenic diet in mental illness
    23:50 Protein, amino acids, and neurotransmitters
    26:00 The role for psychiatric medications
    28:30 Coaching lifestyle changes and motivation
    31:50 Therapy and counseling
    35:12 The Fireball

    Additional Resources:

    Everest Functional Psychiatry and Wellness

    Genova Connect  **PROMO CODE TheLabReport20 for 20% off your purchase**

    Subscribe, Rate, & Review The Lab Report

    Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

    Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net.

    And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

    To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

    Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. 
    See omnystudio.com/listener for privacy information.

    • 39 min
    The Benefits of Berberine

    The Benefits of Berberine

    Berberine is an alkaloid compound that can be extracted from several plants. It is a widely used supplement in personalized medicine and is also beginning to get some traction within the conventional medicine space. Berberine is mainly used in the GI tract for its antimicrobial effects, but as it relates to gut health, that’s just the tip of the iceberg. What is even more fascinating is berberine’s vast systemic metabolic influences.

    In today’s episode, we dive into the wide array of berberine’s important effects. Not only on the gut, but also on detoxification systems, skin, eyes, lipid and blood glucose control, hypertension, and cardiovascular health.

    Today on The Lab Report:


    4:00 Berberine – not an herb – where does it come from?
    6:55 Overall gut modulator, skin health, and detox
    13:05 Metabolic dysfunction – blood glucose, protein, lipids
    14:50 Cardiovascular effects and heart health
    16:00 Contraindications and safety considerations
    18:00 What’s in a name?

    Subscribe, Rate, & Review The Lab Report

    Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

    Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net.

    And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

    To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

    Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
    See omnystudio.com/listener for privacy information.

    • 24 min
    Healthy Gut, Healthy Skin with Dr. Nigma Talib

    Healthy Gut, Healthy Skin with Dr. Nigma Talib

    For decades Dr. Nigma Talib has been helping patients using her clinical expertise in naturopathic medicine. Her contributions to the field are recognized globally. Dr. Nigma has authored best-selling books such as “Reverse the Signs of Ageing” and “Younger Skin Starts in the Gut.” She was one of the first pioneers to introduce vitamin supplements in the fashion industry and she’s responsible for the radiant, glowing skin of some of Hollywood’s most famous faces.

    In today’s episode, we are honored to meet Dr. Nigma Talib. We discuss her holistic approach to health and learn her skincare tips and tricks to reverse the signs of ageing.

    Today on The Lab Report:


    3:50 Meet Dr. Nigma Talib
    9:40 The importance of gut health in aging
    12:40 Nutrition and skin
    15:20 Dr. Nigma’s skincare products
    16:55 Hydration
    18:15 Light and radio frequency
    20:00 Vampire facials and PRP
    25:30 The Fireball

    Additional Resources:

    Dr. Nigma's website

    Shop Dr. Nigma's products

    Genova Connect  **PROMO CODE TheLabReport20 for 20% off your purchase**

    Subscribe, Rate, & Review The Lab Report

    Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

    Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net.

    And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

    To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

    Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
    See omnystudio.com/listener for privacy information.

    • 30 min

Customer Reviews

4.7 out of 5
106 Ratings

106 Ratings

Pennstate Teri ,

Omg! Best podcast ever!

Learning so much! Having so much fun. Great chemistry and great info! Love Patti and Michael.

Avocado57 ,

Good info, annoyingly amateur

Or is it immature? I just can’t stand the banter/patter of the hosts like watching those presenters at awards shows. And I just listened to the Berberine episode which had excellent info and then ended up with some bizarre Musical overlay like they were trying to sound like they were DJing in a club. Just awful. Practitioners like me find this very amateur and annoying. I see that some love it - not me.

Lienna M ,

One of my favorite podcasts

I love this podcast. There is always so much wisdom, clinical insides and actionable steps. As a health care provider myself (functional medicine nutritionist), I always learn new things that I can apply in my own practice to help patients. I highly recommend this podcast. ❤️🥑

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