The Lab Report

Genova Diagnostics, Inc
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The Lab Report

The world of medicine can be challenging. Clinicians and patients are always looking for more options, more effective treatments… and in the end, more answers. What if there was a way to practice medicine that digs deeper and offers a new perspective? Functional medicine focuses on addressing root causes of disease. At Genova Diagnostics we’ve watched this field evolve and grow for over 35 years…. We’ve not only adapted, we’ve led. Join us as we talk about functional medicine, laboratory testing, and optimizing health. Welcome to the Lab Report.

  1. Weathering the Storm: Community, Mental Health, and the Path to Recovery Post-Hurricane Helene

    NOV 4

    Weathering the Storm: Community, Mental Health, and the Path to Recovery Post-Hurricane Helene

    Where to begin? It’s been a few weeks since you’ve heard from us – thank you so much for your amazing support and patience. As you may know, Hurricane Helene brought devastation to western North Carolina, eastern Tennessee, South Carolina, Georgia, and Florida. Genova Diagnostics is headquartered in the heart of Asheville, North Carolina. With that, it’s been a challenging few weeks. But the heroic efforts of many, and the resilient spirit of our team have us back up and running. Genova continues to support our local community- many of whom are still struggling and have lost everything. #WNCStrong Today’s episode is a bit different than usual. It’s our story. Our lessons learned. Genova’s story of resilience when faced with a devastating, historic hurricane. Additional Resources: Genova Connect Manna Food Bank Eblen Charities United Way Asheville Beloved Asheville Habitat for Humanity - AVL   Rural Organizing and Resilience Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

    26 min
  2. This Podcast Will Give You Heartburn

    SEP 17

    This Podcast Will Give You Heartburn

    Gastroesophageal reflux disease (GERD), or heartburn, is incredibly common as is the use of stomach acid suppressing medication. But what if there is far more to the story than stomach acid? There are many other factors to consider in a patient with heartburn. We are going to dive into the physiology of gastric acid, gastric hormonal signaling, and a slew of medications and foods that might be the real culprit. Are PPI’s over prescribed? Are we missing the picture? Tune in to find out. In today’s episode, we tackle some burning questions about GERD and try to get to the root cause. Are acid suppressing medications always the answer? Perhaps the story is not that simple. Today on The Lab Report: 3:45 Conventional medicine’s approach to GERD 6:30 The roll of the lower esophageal sphincter (LES) 8:15 Stomach acid and gastric hormonal signaling 13:20 Foods that affect the LES 14:15 PPI’s - controversy and weaning 18:00 Prescriptive meds, lifestyle, and the LES 19:50 Hiatal hernias 21:30 Question of the Day How does hypochlorhydria or PPI use affect Genova testing? Additional Resources: Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

    28 min
  3. What are Nootropics?

    SEP 4

    What are Nootropics?

    Occasionally, there are new and novel things introduced into the functional medicine and biohacker space that catch our attention. Lately, you might have heard a lot of people talking about the amazing health benefits of “nootropics,” but what are they? Coming from the name of the Greek word Nous (meaning “mind”), nootropics are medicines designed to improve cognitive function and protect the brain. Many of us could use a healthy dose of cognitive support to help us through our busy lives, but what is the truth about nootropics and where can we find them?   In today’s episode, we discuss the what, how, and why of nootropics. We explain what things are considered nootropics and how they work in the body. We also discuss what may be unexpected nootropic things you can do everyday that may not even be termed a nootropic. Listen for more information on how you can help get the most out of your cognition. Today on The Lab Report: 3:30 There’s a lot of buzz about nootropics 4:30 Defining Terms: Nootropics 6:30 Michael rants on what is not a nootropic? 8:30 How do nootropics work in the body? 10:30 Vinpocetine 12:55 Huperzine A and brain energy 15:00 Astaxanthin - not just for flamingos 18:00 Nootropic herbs – aka “adaptogens” 22:10 Ginkgo biloba – a powerful nootropic 24:15 Are there side effects?   Additional Resources: Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.   See omnystudio.com/listener for privacy information.

    28 min
  4. Are We Really Talking About Artichokes?

    AUG 27

    Are We Really Talking About Artichokes?

    Ok, we know what you’re thinking…. Artichokes? Really? Yes really. It may seem a bit out of left field, but you’d be surprised at the many health benefits from either eating artichokes or taking an extract supplement. As a vegetable, it contains fiber, vitamins, minerals, and antioxidants. Extracts made from artichoke leaves, stems, and roots have been used as nutraceutical agents to support the GI tract, liver, and cardiovascular system. But why? In this episode, we peel back the layers of the artichoke – a very mysterious plant indeed.  Is it possible to boost your health with artichoke leaf extract? Tune in to find out! Today on The Lab Report: 3:25 Random artichoke topic – functional food 4:30 Jerusalem artichoke globe artichoke 6:00 Fruit, vegetable, and flowers - Extract vs. Whole food 8:15 Gut and liver health   10:35 Milk thistle vs. artichoke 12:30 Artichoke extract is antimicrobial 14:50 Powerful impact in IBD 18:00 Cardiovascular disease, neurodegenerative disease, cancer 20:00 Artichoke Game Time!! Additional Resources: Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

    27 min
  5. Mast Cell Activation Syndrome & Histamine [Rebroadcast]

    AUG 20

    Mast Cell Activation Syndrome & Histamine [Rebroadcast]

    Mast Cell Activation Syndrome (MCAS) has become a hot topic in functional medicine. Mast cells are an integral part of the body’s immune system. They can be found in areas of exposure such as mucosal membranes, the lining of the GI tract, skin, and airways. Mast cells are responsible for storing important chemical mediators like histamine and others which help to instigate allergic responses. Mast cell disorders arise when there are too many mast cells, or they become hyperreactive. That being said, these conditions are often misunderstood, and diagnoses are sometimes misused.  In today’s episode, we focus on the role of mast cells and histamine in the immune response. We discuss the different mast cell activation disorders, how to diagnose them, and what you can do about it.   Today on The Lab Report:   3:05 Mast Cell Activation Diseases 5:15 What is a mast cell? Why do we care? 7:05 Symptoms of histamine release 8:40 Histamine intolerance vs. MCAS 11:11 Foods: High Histamine or Low Histamine? 14:25 Non-food related histamine associations 15:30 Diagnosing and treating MCAS  18:00 Question of the Day What Genova profiles can help parse out histamine intolerance v. MCAS? Additional Resources: IgE Food Antibodies Profile IgE Inhalants - Allergy Profile IgE Mold - Allergy Profile Methylation Panel Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

    22 min
  6. Desulfovibrio - Friend or Foe?

    AUG 13

    Desulfovibrio - Friend or Foe?

    The gut microbiome harbors trillions of commensal organisms which play a central role in our health. This community is sometimes referred to as our hidden metabolic organ due to its immense impact. Our diet and lifestyle play an important role in feeding the microbiome and keeping the colonies in balance. Should we be concerned if any one bacterial colony overgrows? Today we discuss the commensal bacteria Desulfovibrio. Since this genus of bacteria can reduce sulfate and make hydrogen sulfide gas, overgrowth can have clinical implications. Listen in for more information on why you should care and what you can do about it. Today on The Lab Report: 2:45 Why Desulfovibrio? Define Some Terms!   Commensalism 5:20 Desulfovibrio – what does it do? Why that name? 7:10 Hydrogen sulfide gas – symptoms and its role 9:00 IBD and Desulfovibrio 10:00 Can you have DV and be healthy? 11:00 Other correlations – neurodegenerative disease, autism, metabolic syndrome, cancer 13:45 Pre- and pro-biotics as treatment adjuncts and the Naturopathic Therapeutic Order 17:09 Fructo-oligosaccharides and prebiotics to feed the microbiome – it depends 19:30 Question of the Day Does the GI Effects measure other sulfur-reducing bacteria? 21:15 Evolving research – Desulfovibrio and GLP-1 hormones Additional Resources: Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** GI Effects Stool Profile Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

    24 min
  7. What the heck is mTOR?

    AUG 6

    What the heck is mTOR?

    There are a lot of terms bantered about in the biohacker and longevity space. With that, you’ve likely heard of mTOR – mechanistic (mammalian) target of rapamycin. But what exactly is it? mTOR is a key regulator in your body’s metabolic and growth processes. It integrates various signals, including nutrients and growth factors, to control processes like protein synthesis, autophagy, and lipid metabolism. Because it regulates growth, dysregulation of mTOR has been implicated in various diseases, including cancer. In today’s episode, we simplify the science behind mTOR – mechanistic target of rapamycin. This crucial enzyme may be the key to unlocking groundbreaking advancements in wellness, anti-aging, disease prevention, and health optimization. Today on The Lab Report: 3:00 mTOR – Why are we even covering this topic? 4:40 What is it? Muscle growth vs. autophagy 6:25 Why is it called mTOR? 9:00 Highly conserved and in every cell, every organ 10:30 mTORC1 and mTORC2 11:25 Influences and sensors – it’s more than leucine 14:25 Dysregulation of mTOR – does protein cause cancer? 17:30 Should people take rapamycin for longevity? 20:20 Question of the Day Where does mTOR work in muscle protein synthesis? Additional Resources: Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

    25 min
  8. The Multi-Omics Series Part 4: CBS and Transsulfuration [Rebroadcast]

    JUL 30

    The Multi-Omics Series Part 4: CBS and Transsulfuration [Rebroadcast]

    Multi-omics is the layering of genetic information (genomics) with laboratory biomarker results (metabolomics) to understand the root cause of disease and risk. This educational series focuses on genetic variants in specific enzymes and explains how to evaluate the systemic effects. Today’s episode revolves around the enzyme cystathionine-beta-synthase (CBS). This enzyme is important for homocysteine metabolism, sitting at a branch point between two important cycles: methylation and transsulfuration. The action of this enzyme is important for balancing the critical functions of methylation with the creation of glutathione and energy. Listen to understand why this enzyme is important and what a genetic variant in CBS might mean for you and your patients. Today on The Lab Report: 2:20 Reminder of what we mean by multi-omics 4:50 Introducing the CBS enzyme and the sink drain metaphor 7:40 The genetics of CBS – the silent mutation – and its potential effects 12:40 Better Know A Biomarker:  Cystathionine! 16:20 Activators and inhibitors of CBS and its effects on other biomarkers 18:55 Question of the Day:  Does a CBS SNP cause elevated ammonia levels? 21:40 Evaluating surrounding biomarkers and how do you treat this SNP? Additional Resources: Methylation Panel Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

    26 min
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4.7
out of 5
113 Ratings

About

The world of medicine can be challenging. Clinicians and patients are always looking for more options, more effective treatments… and in the end, more answers. What if there was a way to practice medicine that digs deeper and offers a new perspective? Functional medicine focuses on addressing root causes of disease. At Genova Diagnostics we’ve watched this field evolve and grow for over 35 years…. We’ve not only adapted, we’ve led. Join us as we talk about functional medicine, laboratory testing, and optimizing health. Welcome to the Lab Report.

Information

  • Creator
    Genova Diagnostics, Inc
  • Years Active
    2020 - 2024
  • Episodes
    300
  • Rating
    Clean
  • Copyright
    © 2024 Genova Diagnostics, Inc
  • Show Website
    The Lab Report

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