Theoretical Physics - From Outer Space to Plasma Oxford University

Prof Alexander Mietke discusses recent findings in this field that have linked chirality in living systems to the formation of a left-right body axis in organisms and to a new kind of elasticity that is found in crystals formed by starfish embryos. Chirality describes objects and features that are distinct from their mirror image, a property that can be found in many biological systems ranging from spiral patterns of seashells over helical swimming paths of sperm cells to the shape of our hands and feet. This is rather surprising, given that most organisms develop from a single, round cell which shows no obvious signs of chirality. The physics of chirality in biological systems is a research area within the modern field of living matter that aims to identify the physical principals that underlie how chirality emerges during organism development and how the chiral nature of biological materials contributes to their highly unconventional mechanical properties

Dr Adrien Hallou presents a new methodology called 'spatial mechano-transcriptomics', which allows the simultaneous measurement of the mechanical and transcriptional states of cells in a multicellular tissue at single cell resolution. Over the last 10 years, advances in microscopy and genome sequencing have revolutionised our understanding of how molecular programmes contained in the genome control cellular behaviours such as cell division, differentiation or death, and how these behaviours are influenced by biochemical and mechanical signals from the cell environment. In this talk, I will present a new methodology called 'spatial mechano-transcriptomics', which allows the simultaneous measurement of the mechanical and transcriptional states of cells in a multicellular tissue at single cell resolution. This new framework provides a generic scheme for exploring the interplay of biomolecular and mechanical cues in tissues in a variety of contexts, such as embryonic development, tissue homeostasis and regeneration, but also in diseases such as cancer.

Professor Julia Yeomans describes how mechanical models are being extended to incorporate the unique properties of living systems Epithelial tissues cover the outer surfaces of the body and line the body’s internal cavities. The motion of epithelial cells is key to many life processes: turnover of skin cells, embryogenesis, the spread of cancer and wound healing. Much remains to be understood about the ways in which cells interact and move together. I will describe how mechanical models are being extended to incorporate the unique properties of living systems.

In this talk, Benedikt Placke introduces QEC and explains how the unique interplay between the classical and the quantum world enables us to efficiently correct errors effecting such systems. Quantum computing is a new model of computation that holds the promise of significantly improved performance over classical computing for some problems of interest. However, by its very nature quantum computers are sensitive to disturbance by external noise, most likely necessitating the use quantum error correction (QEC) for useful application.

Furthermore, Benedikt Placke comments on the deep connection between QEC and questions in condensed matter physics.

In this talk Alessio Lerose discusses the seminal idea of simulating Nature via a controllable quantum system rather than a classical computer. He discusses recent advances that brought us closer to the ultimate goal of a universal quantum simulator. Since their birth computers proved invaluable tools for physics research. Quantum mechanics, however, fundamentally challenges the possibility for computers to simulate dynamics of matter. In fact, solving the quantum-mechanical law of motion requires to account for contributions of all possible joint configuration histories of all constituents of a system: a task that quickly becomes unbearable for any imaginable computer. Our understanding of complex phenomena involving important quantum-mechanical effects, such as chemical reactions, high-temperature superconducting materials, as well as the primordial universe evolution, is obstructed by this fundamental technological limitation.

Jasmine Brewer covers recent progress on studying the properties of the quark-gluon plasma, and describe how we can capitalize on lessons learned from high-energy physics to provide new insights on this novel material. Quarks and gluons are the fundamental constituents of all matter in the universe, but they have the unique property that they are always confined inside hadrons. The only situation in which quarks and gluons are deconfined is in extremely high-energy collisions of heavy nuclei, where the temperature is so high that nuclei “melt” into a new phase of matter called the quark-gluon plasma. This exotic state of matter provides a gateway to study the rich many-body physics of free quarks and gluons, including their rapid thermalization to form the most perfect liquid ever observed.