This Week in Virology

Vincent Racaniello
This Week in Virology

TWiV is a weekly netcast about viruses - the kind that make you sick. Professors Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler and science writer Alan Dove and guests deconstruct viruses, how they cause illness, and dissect the latest research.

  1. 1D AGO

    Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin with Vincent Racaniello deplore the US’s withdrawal from the global health community for pandemic preparedness i.e. the universal avian flu vaccine, and undermining the use of routine childhood vaccinations for pertussis and measles, RFK’s autism registry, yellow fever outbreak in Colombia and world immunization week after discussing the squirrel as the reservoir host for mpox, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections the WasterwaterScan dashboard, how immunity elicited by the RSV vaccine wanes in 3 years, if Paxlovid reduces stroke, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, if vaccination impacts long COVID and if long COVID were to become epidemic. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode The American Public’s Disengagement With Highly Pathogenic Avian Influenza (HPAI): Considerations for Vaccination and Dietary Changes(American Public Health Association) New agreement geared toward universal avian flu vaccine (CIDRAP) Cambridge’s DIOSynVax and Singapore’s ACM Biolabs to advance pandemic-ready universal bird flu vaccine with international support (GlobeNewswire) Bird flu continues to spread among live poultry markets after shut down order  (CRAIN’S New York Business) Fire-footed rope squirrels (Funisciurus pyrropus) are a reservoir host of monkeypox virus (Orthopoxvirus monkeypox)(Research Square) It is a squirrel! An animal source of mpox emerges(Nature) Whooping cough spikes, especially among unvaccinated teens (NBC News) A February flu surge has arrived (NCB News) Pertussis Cases by Year (1922-2022)(CDC: Whooping cough (pertussis))) ‘Fighting to breathe’: Whooping cough surges as vaccination rate falters (NBC News) CDC cancels measles help for Texas schools amid staff layoffs (HealthDay) Measles cases and outbreaks (CDC Rubeola) Measles in Texas…. (Texas Health and Human Services) Measles vaccine recommendations from NYP (jpg)  2025 Measles outbreak guidance (New Mexico Health) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Measles (CDC: Measles Rubeola) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) RFK Jr.’s autism registry plan (Axios) RFK Jr’s autism study collecting Americans’ private medical records (Guardian) The public’s views on measles outbreaks and misinformation (KFF)  Colombia National Emergency: yellow fever cases (Gov.Co) World Immunization Week: polio eradiation?(GPEI) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Respiratory virus activity levels (CDC Respiratory Illnesses) 200 children die from flu (CIDRAP) Weekly surveillance report: clift notes (CDC FluView) FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Trial shows waning efficacy of RSV vaccine across 3 seasons in older adults(CIDRAP) Efficacy, safety, and immunogenicity of the AS01E-adjuvanted respiratory syncytial virus prefusion F protein vaccine (RSVPreF3 OA) (LANCET: Respiratory Medicine) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Long-term stroke and mortality risk reduction associated with acute-phase paxlovid use in mild-to-moderate COVID-19(Journal of Medical Virology) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID The effect of COVID-19 vaccination on the risk of persistent post–COVID-19 condition (JID) ORCHESTRA Delphi consensus: diagnostic and therapeutic management of Post-COVID-19 condition in vulnerable populations (CMI Clinical Microbiology and Infection) Political ideology and trust in scientists in the USA(Nature Human Behavior) Leading long COVID researcher fears it could become a national epidemic (Spectrum News NY1) Center for post COVID care (Mt. Sinai) Reaching out to US house representative Letters read on TWiV 1212 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

    48 min
  2. APR 19

    Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin with Vincent Racaniello rue about the continuation of the gutting of the American public health infrastructure, the continuing measles outbreak, an unreported outbreak of deadly E.coli human infections, meningococcal disease before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, ACIP recommended changes in guidelines for the RSV and COVID-19 vaccines, reactogenicity differences between Novavax and Pfizer COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, effects of long COVID in children and adolescents and a list of ongoing clinical trials for long COVID treatment. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Making America Healthy Again-purging of administrators at HHS (Politico) Making America Healthy Again-purging of data (Politico) Deep cuts of the federal government (NY Times) Cutting NIH, CDC and HHS promotes chronic disease research(Washington Post) Political ideology and trust in scientists in the USA(Nature Human Behavior) US political conservatives have deep, unbudging suspicion of science, survey suggests(CIDRAP) A deadly E. coli outbreak hit 15 states, but the FDA chose not to publicize it(NBC News) Invasive meningococcal disease – Kingdom of Saudi Arabia(WHO) The essential guide to understanding the differences between hajj and umrah (Marhabahaji) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Measles booster? (Washington Post) How to stop an outbreak…….fire the experts (Washington Post) Measles cases and outbreaks (CDC Rubeola) Measles 159 in Texas…. (Texas Health and Human Services) 2025 Measles outbreak guidance (New Mexico Health) Measles and rubella weekly monitoring (Government of Canada) Measles vaccine recommendations from NYP (jpg) NAFMA: North American Free Measles agreement…..(NY Times) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Doctors’ talk measles (YouTube) Measles (CDC: Measles Rubeola) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Respiratory virus activity levels (CDC Respiratory Illnesses) 200 children die from flu (CIDRAP) Weekly surveillance report: clift notes (CDC FluView) FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) ACIP votes to expand recommendation for Pfizer’sRSV vaccine Abrysvo® to include adults aged 50 to 59 at increased risk of disease (Pfizer) Respiratory syncytial virus and incidence of cardiovascular events: a nationwide self-controlled case series analysis (JACC Journals) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Comorbidities associated with different degrees of severity in children and young people hospitalized with acute COVID-19 (Pediatric Infectious Disease Journal) SHIELD-Utah study shows Novavax’s COVID-19 vaccine induces lower reactogenicity symptoms compared to mRNA (Novavax) Interim clinical considerations for use of COVID-19 vaccines in the United States (CDC Vaccines & Immunizations) Novavax says its COVID vaccine produces fewer, milder reactions than Pfizer version(CIDRAP) US CDC advisers discuss narrower use of COVID-19 vaccines (Reuters) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusions center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Kidney Function following COVID-19 in children and adolescents(JAMA Network Open) Cardiovascular post-acute sequelae of SARS-CoV-2 in children and adolescents: cohort study using electronic health records(Nature Communications) Great barrington declaration (gbdeclaration.org) Clinical trials: Effectiveness of transcranial direct current in patients with persistent COVID-19 with headaches and chronic pain. Home-based Brain Stimulation Treatment for Post-acute Sequelae of COVID-19 (PASC) Acupuncture for post COVID-19 Condition (Long COVID) neuropsychiatric symptoms Pain relief with integrative medicine (prime)?: feasibility of acupuncture for long COVID Electro-acupuncture for long COVID neuropsychiatric symptoms Randomised study to investigate the effectiveness of acupuncture for the relief of long COIVD-19 related fatigue (ACU-COVID) Vagus stimulation in female long COVID patients.(Vagus) Stellate ganglion block with lidocaine for the treatment of COVID-19-induced parosmia (Stella) Therapeutic updates on long COVID: Where things stand 5 years later (ID Society) Reaching out to US house representative Letters read on TWiV 1210 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

    47 min
  3. APR 12

    Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin with Vincent Racaniello mourn the demise of vaccination against childhood diseases when discussing the continuing measles outbreak and the rise of pertussis, the first human case of H5N1 in Mexico, and human metapneumovirus before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections and vaccination schedules, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, if antiviral therapy prevents long COVID and how long COVID may affect brain volume. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode A natural experiment on the effect of herpes zoster vaccination on dementia (Nature) Taking a shot at dementia (microbeTV: TWiV) RFK Jr. visits Texas after second child dies of measles amid outbreak (Washington Post) Kennedy Attends Funeral of Texas Girl Who Died of Measles(NY Times) ‘Most effective way’ to prevent measles is vaccination, RFK Jr. says, in most direct remarks yet (STAT News) Fort Bliss…..Fort measles: Beaumont Army hospital confirms measles case at Fort Bliss(KTSM News) Measles cases and outbreaks (CDC Rubeola) Measles 159 in Texas…. (Texas Health and Human Services) Measles vaccine recommendations from NYP (jpg) 2025 Measles outbreak guidance (New Mexico Health) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Doctors’ talk measles (YouTube) Measles (CDC: Measles Rubeola) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Two infants die of whooping cough in Louisiana (CNN) Clinical features of pertussis (CDC: Whooping cough Pertussis) Pertussis vaccination recommendations (CDC: Whooping cough Pertussis) Diphtheria vaccination (CDC: Diphtheria) Mexico’s first human case of H5N1 (Reuters) Human metapneumovirus seasonality and co-circulation with respiratory syncytial virus — United States, 2014–2024 (CDC: MMWR) Influenza: Wastewater scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Respiratory virus activity levels (CDC Respiratory Illnesses) FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Human source SARS-CoV-2 aerosol transmission to remote sentinel hamsters (OFID) Interim clinical considerations for use of COVID-19 vaccines in the United States (CDC Vaccines & Immunizations) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Fusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Infectious Disease Society guidelines for treatment and management (ID Society) Cost-effectiveness analysis of nirmatrelvir/ritonavir for high-risk individuals with COVID-19….does this mean use the big button calculator? (OFID) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Nirmatrelvir–ritonavir versus placebo–ritonavir in individuals with long COVID in the USA (PAX LC): (LANCET: Infectious Diseases) Quantitative brain volume differences between COVID-19 patients and non-COVID-19 volunteers (NeuroImage) Donepezil for fatigue and psychological symptoms in post–covid-19 condition (JAMA Network Open) Letters read on TWiV 1208 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

    50 min
    4.8
    out of 5
    2,018 Ratings

    About

    TWiV is a weekly netcast about viruses - the kind that make you sick. Professors Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler and science writer Alan Dove and guests deconstruct viruses, how they cause illness, and dissect the latest research.

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