Infectious Disease Puscast Vincent Racaniello

On episode #42 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/09 – 11/21/23.
Host: Daniel Griffin and Sara Dong
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Links for this episode Progress toward measles elimination (CDC) Slaying the troll of transplantation (TID) Association between the neutrophil-to-lymphocyte ratio and adverse outcomes in children aged Pre-exposure prophylaxis use history in people with antiretroviral resistance at HIV diagnosis (CID) Impact of the 2019 FDA guidance for uncomplicated UTI on treatment response rates (OFID) CDC Guidelines for the prevention and treatment of anthrax (CDC) Contemporary use of cefazolin for MSSA infective endocarditis (IJID) Is carbapenem therapy necessary for treatment of non-CTX-M ESBL-producing Enterobacterales bloodstream infections (CID) Infectious diseases consultation associated with reduced mortality in gram-negative Bacteremia (CID) Contemporary management of Staphylococcus aureus bacteremia (CID) Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal (Nature) Impact of in-house Candida auris PCR screening on admission on the incidence rates of surveillance and blood cultures with C. auris and associated cost savings (OFID) Human lobomycosis caused by Paracoccidioides loboi (EID) Molecular surveillance detects high prevalence of the neglected parasite Mansonella ozzardi (JID) Efficacy and safety of moxidectin compared with ivermectin against Strongyloides stercoralis infection in adults (The Lancet) Efficacy of bortezomib for treating anti-interferon-gamma autoantibody-associated adult-onset immunodeficiency (AOID) syndrome (CID) Investigational non-antibiotic therapeutics for infections in hematopoietic cell transplant recipients and patients with hematologic malignancies receiving cellular therapies (TID) Black box warning: large language models and the future of infectious diseases consultations (CID) Music is by Ronald Jenkees

On episode #41 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/26 - 11/08/23.
  Host: Daniel Griffin and Sara Dong
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Links for this episode Intrinsic and effective severity of COVID-19 cases infected with the ancestral strain and Omicron BA.2 variant in Hong Kong (JID) Efficacy and safety of corticosteroid therapy for community-acquired pneumonia (CID) Hydrocortisone in severe community-acquired pneumonia (NEJM) Early oral antibiotic switch in Staphylococcus aureus bacteraemia (CID) Outbreak of invasive Group A Streptococcus in children (PIDS) Inhaled amikacin to prevent ventilator-associated pneumonia (NEJM) Assessing risk for complications in acute hematogenous osteomyelitis in children (JPIDS) Empirical antibiotic therapy in diabetic foot ulcer infection increases hospitalization(OFID) 2023 guideline on diagnosis and management of acute bacterial arthritis in pediatrics (JPIDS) Natural history of antibiotic-treated lower limb cellulitis (OFID) Missed opportunities for preventing congenital syphilis (CDC) Diverse clinical manifestations and challenges of mucormycosis (OFID) Malaria (The Lancet) Clinical characteristics and outcomes of Chagas disease (AJTMH)  Direct gloving vs hand hygiene before donning gloves in adherence to hospital infection control practices (JAMA) How I approach diarrhea in hematological transplant patients (TID) Innovating pediatric infectious diseases recruitment and training (JPIDS) Music is by Ronald Jenkees

On episode #40 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/13 – 10/25/23.
Host: Daniel Griffin and Sara Dong
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Links for this episode Sustained viral suppression with dolutegravir monotherapy over 192 weeks in patients starting combination antiretroviral therapy during primary HIV infection (CID) Dolutegravir monotherapy possibly boosted by highly active natural immunity (CID) Mpox neutralizing antibodies at 6 months from mpox infection or MVA-BN vaccination (The Lancet) Linezolid population pharmacokinetic model in plasma and cerebrospinal fluid among patients with tuberculosis meningitis (JID) Adjunctive dexamethasone for tuberculous meningitis in HIV-positive adults (NEJM) Cefepime vs piperacillin-tazobactam in adults hospitalized with acute infection (JAMA) Acute kidney injury with empirical antibiotics for sepsis (JAMA) Mycobacterium abscessus outbreak related to contaminated water among  ventilator-dependent residents of a pediatric facility (CDC) Trial of Vancomycin and Cefazolin as surgical prophylaxis in arthroplasty (NEJM) Trimethoprim-sulfamethoxazole significantly reduces the risk of nocardiosis in solid organ transplant recipients (CMI) Risk of hematologic cancers among individuals tested for Borrelia burgdorferi antibodies, and Borrelia burgdorferi seropositive individuals (CMI) In vitro susceptibility patterns for slowly growing non-tuberculous mycobacteria (JAC) Real-world use of mold-active triazole prophylaxis in the prevention of invasive fungal diseases (OFID) Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19 (INI) Real-time dermoscopy of numerous mites crawling on the crusted scabies (CMI) The African eye worm: current understanding of the epidemiology, clinical disease, and treatment of loiasis (The Lancet) Decolonization in nursing homes to prevent infection and hospitalization (NEJM) Can chatbot artificial intelligence replace ID physicians in the management of bloodstream infections (CID) Nasal iodophor antiseptic vs nasal mupirocin antibiotic in the setting of chlorhexidine bathing to prevent infections in ICUs (JAMA) FDA Approves PENBRAYATM for the prevention of the five most common serogroups causing meningococcal disease in adolescents (Pfizer) Music is by Ronald Jenkees

On episode #39 of the Infectious Disease Puscast, recorded at IDWeek in Boston, Daniel and special host Priya Kodiyanplakkal review the infectious disease literature for the weeks of 9/27 – 10/12/23.
Host: Daniel Griffin and Priya Kodiyanplakkal
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Links for this episode Survival from rabies in a young child from India (AJTMH) The perils of overly-sensitive viral load testing for persons living with HIV (OFID) Letermovir vs Valganciclovir for prophylaxis of Cytomegalovirus in high-risk kidney transplant recipients (JAMA) Frailty and survival in the 1918 influenza pandemic (PNAS) Adverse pregnancy outcomes among HIV-infected Women taking isoniazid preventive therapy during the first trimester (CID) Ceftobiprole for treatment of complicated Staphylococcus aureus bacteremia (NEJM) Real-world application of oral therapy for infective endocarditis (CID) Efficacy and safety of sulbactam–durlobactam versus colistin for the treatment of patients with serious infections (The Lancet) Information delay of significant bloodstream isolates and patient mortality (CID) Critical appraisal beyond clinical guidelines for intra-abdominal candidiasis (CC) Update on outbreak of fungal meningitis among Americans who received epidural anesthesia at clinics in Mexico Increasing prevalence of artemisinin-resistant HRP2-negative malaria in Eritrea (NEJM) Gender differences in psychosocial determinants of hand hygiene among physicians (ICHE) Music is by Ronald Jenkees

On episode #38 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 9/14 – 9/27/23.
Host: Daniel Griffin and Sara Dong
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Links for this episode Features of Long COVID identified through immune profiling (Nature) Severity of influenza-associated hospitalizations by influenza type (The Lancet) Cefazolin for the treatment of CNS infections (CID) Rifampin based therapy for patients with Staphylococcus aureus native vertebral Osteomyelitis (CID) State of the management of infections caused by multidrug-resistant organisms (CID) Are contact precautions “essential” for the prevention of healthcare-associated methicillin-resistant Staphylococcus aureus? (CID) Impact of the sequential implementation of a pharmacy-driven methicillin-resistant Staphylococcus aureus (MRSA) nasal-swab ordering policy and vancomycin 72-hour restriction protocol on standardized antibiotic administration ratio (ICHE) Update on outbreak of fungal meningitis among US residents who received epidural anesthesia at two clinics in Mexico (CID) Paratracheal abscess by plant fungus Chondrostereum purpureum (MMCR) Canadian Blood Services traceback investigation of a suspected case of transfusion-transmitted malaria (Transfusion) Strongyloides infection screening in transplant candidates (TID) The world of microbial odors (JID) Music is by Ronald Jenkees

On episode #37 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 8/31 – 9/13/23.
Host: Daniel Griffin and Sara Dong
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Download Puscast 037 (22 MB .mp3, 31 min)
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Links for this episode
Association between varicella zoster virus and dementia (NS) Safety, efficacy, and immunogenicity of V160 vaccine in cytomegalovirus-seronegative women (The Lancet) Microorganisms detected in intussusception cases and controls in children (OFID) Clinician testing and treatment thresholds for management of UTIs (OFID) Clinical outcomes and management of NAAT-positive/toxin-negative Clostridioides difficile infection (CID) Associations of standard care, intrathecal antibiotics, and antibiotic impregnated catheters with cerebrospinal fluid shunt infection (JPIDS) Advances in asynchronous telemedicine call for increased antibiotic surveillance (CID) Two artificial tears outbreak-associated cases of extensively drug-resistant Pseudomonas aeruginosa detected through whole genome surveillance (JID) Pre-XDR congenital TB in an extremely premature baby (CID) Emerging Roles of (1→3)-β-D-glucan in cerebrospinal fluid for detection and therapeutic monitoring of fungal diseases (CID) Outbreak of locally acquired mosquito-transmitted malaria (CDC) Complexity of infectious diseases compared to other cognitive medical subspecialties (OFID) Risk of opportunistic infections associated with long-term glucocorticoid therapies in adults (CID) Music is by Ronald Jenkees