81 episodes
Understanding Childhood Cancer With Dr Geoff Dr Geoffey McCowage, Senior Paediatric Oncologist, Sydney, Australia
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- Science
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4.5 • 15 Ratings
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Understanding Childhood Cancer with Dr Geoff.
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CAR T-cells, Interview with Dr Caroline Bateman
CAR T-cell therapy is an exciting new treatment for acute leukaemia. In this episode, Dr Geoff interviews his colleague Dr Caroline Bateman about CAR T-cells and introducing the treatment option to her unit. Link to Patreon
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"S" is for "Special" : Stage MS Neuroblastoma (also called Stage IVS, 4S)
There is a special subtype of neuroblastoma seen in very young children, with spread of disease throughout the body, but which needs a very different approach to treatment compared to older children with metastatic disease. This episode explains the features of this stage MS neuroblastoma, the early problems, and the treatment used.
Link to Patreon
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Where did my child's immune system go?
Childhood cancer treatment leads to severe impairment of the ability to fight infections. This episode explains what immune suppression means, what causes it, and the problems that result.
Link to Patreon
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Update re the future of rock and roll.... CAR T-cells
A few years ago I described CAR T-cells, but they weren't available for routine use. I now update things, with the very important news about CAR T-cell therapy now becoming available. There is also an interview with Dr Caroline Bateman re this subject in another episode.
Link to Patreon
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Blood Cultures
We take a lot of blood samples looking for infection in the bloodstream. This episode explains what blood cultures are all about. Link to Patreon
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PRISM, Molecular Profiling, and Informed Consent
A number of countries have research studies where childhood cancers are analysed in great detail, testing all the DNA in something called 'molecular profiling'. The national Australian study of this is called PRISM, and it is a very exciting project. This episode explains a molecular profiling project and covers issues of obtaining informed consent from parents and patients as well. Link to Patreon
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Customer Reviews
DIPG
My daughter died in 2014 from DIPG. I listened to your podcast on what the letters mean. I wish you would do more about the treatments, clinical studies and lack of advances in the tumor like you promised at the end of the episode. However, I think you did a fantastic job explaining the tumor. I LOVED the spaghetti and honey example. Thank you for what you are doing.
Is compassion that hard to muster?
I just discovered your podcast. My daughter completed chemo for ALL Pre-B SR in May 2022. She was on protocol 932, COG. I listened to your episode on ALL. You talked about doing the bone marrow aspiration without anesthesia as if it’s just no big deal for anyone going through it. It’s obvious to me that you have not actually had a sick child. These procedures are a big deal to the parents and kids going through them. Every single one of the 4 BMAs & the 18 LP’s and the 3 port surgeries and her PRES, and her MTX neurotoxicity and her steroid-induced diabetes and her high blood pressure and her permanent damage to the white matter of her brain— IT IS ALL A BIG DEAL. Don’t you dare be glib or flippant about it. And I won’t even begin about port access. Adults ought to be getting local and general anesthesia aplenty for these procedures unless they choose otherwise. There is no excuse whatsoever for cancer care to be barbaric in this day and age. Is it too much to ask for pain control?? For some humane administration of procedures that do, in fact, hurt? Or must you continue to treat cancer patients like farm animals getting ear notches and teeth jerked out? Raise your standard of care & have some frigging humanity.
Great podcast on tough topic
My 12 year old son now has ALL-b leukemia-June 2018- so thankful for this podcast that is calm and realistic to help parents and friends understand the disease and the treatments.