Your One Stop Shop For All Things Self-Improvement Related
Your One Stop Shop For All Things Self-Improvement Related
The Anabolic Steroid Family Tree - A Framework That Simplifies How Different Steroids Impact Muscle Building And Performance
The anabolic steroid family tree is a framework that simplifies how different steroids impact muscle building and performance.
In general, the most commonly used anabolic steroids fall into one of three different families/categories.
Testosterone and its derivatives, Dihydrotestosterone (DHT) and its derivatives, and Nandrolone (19-Nortestosterone) and its derivatives.
Expectedly, many of the anabolic steroids in each family have similar attributes to one another.
There are exceptions to this in each family, but in general breaking down anabolic steroids into the three families provides a simplified framework to identify the targeted action of each compound, as well as how they impact muscle building and overall performance.
Gorilla Mode Nitric Stimulant Free Pre-Workout Review | Comprehensive Supplement Breakdown
Gorilla Mode Nitric Pre-Workout is the most potent and comprehensive stimulant free pre-workout on the market in ALL aspects.
All angles of saturating the muscle with blood and hydration have been addressed in this formula and are quite literally maxed out.
Gorilla Mode Nitric Supplement Facts Per Full Daily Dose:
L-Citrulline – 10,000 mg Creatine Monohydrate – 5000 mg Betaine Anhydrous – 4000 mg GlycerPump™ (65% Glycerol Powder) – 4000 mg Malic Acid – 3000 mg Agmatine Sulfate – 1500 mg Nitrosigine® (inositol-stabilized arginine silicate) – 1500 mg Sodium Nitrate – 1500 mg VasoDrive-AP® (isoleucyl-prolyl-proline (IPP) and valyl-prolyl-proline (VPP) isolated from hydrolyzed milk casein) – 254 mg
Gorilla Mode Nitric Vs. Other Pre-Workouts On The Market This is the most maxed out stimulant free pre-workout formula on the market in all aspects.
It is also the most comprehensive formula that targets nitric oxide (NO), vasodilation and intracellular hyper-hydration from multiple angles, while maintaining top end dosages across all of those pathways.
We completely saturate the traditional Arginine–eNOS–nitric oxide (NO) pathway with a massive 10 gram dose of L-Citrulline, 1.5 grams of Nitrosigine and 1.5 grams of Agmatine Sulfate.
The often neglected nitrate–nitrite–nitric oxide (NO) pathway is also topped out with a 1500 mg dose of Sodium Nitrate.
A high level of intracellular hyper-hydration is achieved with 5 grams of Creatine Monohydrate, 4 grams of Glycerpump and 4 grams of Betaine Anhydrous.
We also addressed the enzyme angiotensin converting enzyme (ACE) with VasoDrive-AP®, which acts as an ACE inhibitor and significantly increases vasodilation.
Finally, we have 3 grams of Malic Acid added in on top of the 10 grams of pure L-Citrulline to act as a Krebs cycle intermediary and counter lactic acid buildup during training.
Some of these pathways are so maxed out that we could have easily just chosen one of them and sold the product for $39.99 and still had one of the most potent pre-workouts in the industry.
Instead, I packed it all into one absurd product that clocks in with over 30 grams of efficacious active ingredients per full dose.
It was incredibly expensive to create, but I am very happy with how it turned out, and I am not exaggerating when I say that this pre-workout is absolutely unmatched.
Basically, I just included exactly what I would want to see in a stimulant free pre-workout, even at the obvious detriment of our margins.
This product is even more potent than Gorilla Mode when it comes to pure pump and performance.
The full daily dose is 2 scoops.
Even a half dose (1 scoop) is still far more potent than the majority of other pre-workouts out there at their max dosages.
This is another product I wanted to be head and shoulders, clear as day, superior to everything else in the industry.
Just like in my description of how Gorilla Mode stacks up to other products in this industry, we can actually back up why our product is better than the rest.
When (insert fitness influencer name here) launches their own supplement line, they will regurgitate the same story about how their products are effectively dosed, only use the highest quality ingredients, blah blah blah.
They don't even know what they're selling half the time, let alone what combinations of ingredients work synergistically, or how to dose a product properly.
They employ others to manufacture their products, or use a pre-made formula their manufacturer uses for every company where they just slap a different label on it and sell it for a huge margin.
At the end of the day, most fitness influencers have no idea what goes into making an effective product.
They don't know how their products work, they probably wouldn’t even use them if they didn’t sell them, they didn't
How Different Anabolic Steroids Can Affect Your Immune System And Vulnerability To Viral Infections
Both Testosterone and anabolic androgenic steroids (AAS) adversely influence the immune system, affecting leucocyte growth or activity, and antibody and cytokine production, particularly when used at supraphysiological doses, mimicking a condition of secondary immunodeficiency [R, R].
Secondary immunodeficiency, much more common than primary immunodeficiency (that is to say those caused by genetic defects affecting the cells of the immune system), is characterized by various factors that affect a normal immune system, including infectious, iatrogenic, metabolic and environmental factors.
These immune deficiencies are manifested clinically with an increased frequency or unusual complications of common infections and occasionally with the onset of opportunistic pathogen infections.
Nandrolone And Anadrol Effects On The Immune System Nandrolone Decanoate and Anadrol directly induce the production of inflammatory cytokines Interleukin 1 Beta (IL-1β) and Tumor Necrosis Factor Alpha (TNF-α) in human peripheral blood leukocyte cultures [R].
Testosterone and DHEA had no direct cytokine inducing effect in the same model.
Nandrolone Decanoate also inhibits interferon production in NDV-infected mouse L-929 and human WISH cells.
Winstrol And Trenbolone Effects On The Immune System Winstrol and Trenbolone were found to be genotoxic and cytotoxic to human lymphocytes in a dose dependent manner [R].
Testosterone, Teslac, Anavar And Winstrol Effects On The Immune System To evaluate how anabolic steroids affect the immune system, five commercially available steroids with various types of structural differences were studied in a rodent model [R].
Animals were divided into five groups and treated with Testosterone (group 1), Testosterone Propionate (Group 2), the steroidal aromatase inhibitor Testolactone (Teslac) (Group 3), Anavar (Group 4), and Winstrol (Group 5).
Significant immunosuppression was observed with all groups.
However, by day 10, the Teslac, Anavar and Winstrol treated group showed immunostimulation and actually exceeded baseline immunity while the Testosterone treated groups maintained immunosuppressed.
To truly test the effects of endogenous androgens on the immune system a second experiment was then performed.
Ten animals maintained in a similar manner to the initial experiment were either treated intact or were castrated and then treated for 8 days, with Anavar (1.1 mg/kg/day), Testosterone (1.1 mg/kg/day) or Anavar combined with physiologic amounts of Testosterone (15 μg/day).
Anavar was selected because it has the greatest anabolic activity of all Testosterone analogues as compared to Testosterone (androgenic/anabolic activity = 1:13).
In the intact animals after 8 days of treatment with Anavar, serum Testosterone levels were measured by radioimmunoassay on tail vein blood.
Levels were either undetectable or very low, reflecting what would be significant HPTA suppression.
Immune function (DCH responses) measured at the same time revealed a 41% increase over baseline.
The Testosterone treated group experienced a 36% suppression of immune function.
Further treatment for 8 days with Anavar combined with physiologic amounts of Testosterone eliminated the immune system enhancement provided by Anavar monotherapy and returned the DCH responses to levels that were not significantly different from baseline.
The results were different in the castrated animals.
Castration, resulted in an increase in immune (DCH) responses.
The mean observed change was 90% greater than intact (pre-castration) baseline.
That means that castrated rats had a 90% improvement above and beyond rats that weren’t castrated.
Eight day administration of Anavar to these animals had an immunodepressive effect returning the DCH response to baseline.
Eight day treatment with Anavar combined with phy
Arnold Schwarzenegger’s Steroid Cycle - Dbol And Primobolan
Arnold Schwarzenegger's steroid cycle from the golden era of bodybuilding is a topic that is often heavily debated.
There's a lot of speculation around what kind of drug use the golden era bodybuilders deployed to get the physiques that are so sought after nowadays.
While Arnold himself never detailed exactly what he took, we have a handful of credible sources of information that all seem to overlap in their descriptions of his steroid use.
Despite this information being very accessible, it often goes overlooked because it is buried in the nooks and crannies of the internet.
There is such an overwhelming amount of content on the internet now that this information has become increasingly more difficult to find over the years.
While Arnold likely experimented a bit here and there, this article will detail what he built his physique on, and the staple anabolics he very likely used throughout his Mr. Olympia reign.
Arnold Schwarzenegger Briefly Touches On His First Steroid Cycle In Arnold Schwarzenegger's autobiography "Total Recall - My Unbelievably True Life Story" he gives some insight into what his first steroid cycle consisted of, and when he started it.
The first thing of note is that he discovered steroid use before the 1967 Mr. Universe competition while researching about the training methods of the East Germans and the Soviets.
There were rumors that they were using performance enhancing drugs to get superior results from their weightlifters, shot-putters, and swimmers and he soon found out that steroids were the drugs that they were using.
Arnold goes on to touch on how he went to a doctor to ask for a prescription of anabolic steroids.
He simply asked:
Can you let me try it?
The doctor agreed, and he was then prescribed an injection every two weeks and pills to take in between.
Keep in mind, this was Arnold's first steroid cycle ever.
His dosages may have titrated up in subsequent cycles, and he probably experimented with different anabolics at some point at least once or twice.
The more muscle you gain, the higher your requirements will become for increasingly high amounts of calories, training volume, and drug use to support additional hypertrophy above and beyond what you have already achieved.
While Arnold didn't state exactly what he was prescribed, we get some useful insight into the administration practice of each compound (oral and injectable) and what type of drugs would probably fall into these two categories at that time when considering all of the other information from other interviews we have compiled over the years.
At this point, we know he was using one injectable compound and one oral compound.
Arnold Schwarzenegger's Interview About Dianabol Use In another interview Arnold more or less implies that he used 3 Dianabol per day.
It is well-known in the community that Arnold was big on using Dianabol back in the day.
Obviously he's not actually straight up saying "this was what my cycle was", but we can put two and two together based on his prescription for pills and an injection from a doctor, Arnold talking about Dianabol himself, and the widespread information that's passed through the grapevine reinforcing his Dianabol use.
It all culminates to paint a pretty convincing picture that Dianabol was the oral steroid in question that Arnold used.
What the injectable compound was is mainly what is debated about.
After doing some digging, I uncovered some pretty convincing information suggesting that the injectable compound was Primobolan.
Steve Davis Outlines Golden Era Steroid Cycles In 2012, Ric Drasin interviewed Steve Davis to discuss steroid cycles from the golden era.
Both men trained at Gold's Gym with Arnold in the 70's and had personal insight into what golden era stacks consisted of, as they literall
Gorilla Mind Smooth Review - Complete Nootropic Formula Breakdown
Gorilla Mind Smooth is the most potent and comprehensive stimulant-free Nootropic formula on the market.
If you don't already know what Nootropics are, they are a category of compounds that can improve cognitive function.
This can extend into many different specific benefits, but the main draw of Nootropics is their impact on productivity, concentration, creativity and information retention.
Gorilla Mind Smooth is our stimulant-free version of Gorilla Mind that provides a smoother, much less extreme level of energy, but still maximizes mental clarity, memory, creativity and focus.
Regardless if you're currently using stimulant-based products (coffee, energy drinks, pre-workouts, etc.), cycling off of stimulants, or just never use stimulants, Gorilla Mind Smooth is the most potent Nootropic formula you can add into your life to enhance cognitive function.
Reviews These are some of the reviews we've received from customers using Gorilla Mind Smooth:
Gorilla Mind Smooth Supplement Facts Per Full Daily Dose:
L-Tyrosine - 1000 mg Organic Lion's Mane Mushroom (Hericium Erinaceus) (standardized to 25% β-glucans) - 1000 mg DMAE (Dimethylaminoethanol) - 750 mg Alpha GPC 50% (L-alpha-glycerylphosphorylcholine) - 600 mg Kanna (Sceletium Tortuosum) - 500 mg Bacopa Monnieri (standardized to 45% Bacosides) - 400 mg L-Theanine - 200 mg Bioperine® (Black Pepper Fruit Extract) (standardized to 95% Piperine) - 10 mg Huperzine A (Huperzia serrata leaf standardized extract) - 400 mcg The original Gorilla Mind Smooth formula had PEA, Hordenine and Teacrine in it.
Originally, I was trying to chase a stimulant-free energy boost in Smooth, which is why I had those ingredients in it.
However, over the past year I've started to really lean towards reformulating Smooth to create an entirely Nootropic comprised formula that is 100% geared towards maxing out cognitive function, rather than chase a relatively weak level of energy that we already destroy with Gorilla Mind Rush.
Anyone buying Gorilla Mind that is using it for the laser focus and massive boost in energy and productivity is buying RUSH anyways, not SMOOTH.
Instead of wasting precious capsule space with things that achieve a subpar level of energy, I decided that space would be far better utilized with other Nootropics.
This is what led to me creating the current Gorilla Mind Smooth formula, which now has 1000 mg of Lion's Mane mushroom and 500 mg of Kanna in it.
These compounds are far more conducive to enhancing the SMOOTH formula by supporting actual brain health, creativity, mental clarity and memory formation.
If you want ridiculous amounts of energy and drive, get RUSH.
For those who want a true stimulant-free Nootropic formula, SMOOTH is even better now and I highly recommend you give it a try.
Gorilla Mind Smooth Vs. Other Nootropics On The Market This is the most maxed out stim-free Nootropic formula on the market.
The full daily dose is 6 capsules.
Even a half dose (3 capsules) is still far more potent than the majority of other Nootropic formulas out there at their max dosages.
I formulated Gorilla Mind Smooth the exact same way I formulate any other product.
I put in exactly what I would buy myself if I were shopping for each Nootropic separately.
If you thought the pre-workout market was bad for underdosed products, your jaw will drop when you see some of the top selling Nootropic formulas.
This industry is even worse because it is so niche and new.
Preying on unsuspecting customers with garbage formulas sprinkled with vitamins and completely useless dosages of Nootropics is even more common in this industry.
Because Nootropics are relatively new and uncharted waters for many, the prices get pretty aggressive on these watered down formulas as well that promise the world, and deliver nothing more than placebo.
The Most Accurate Testosterone Blood Test You Can Get
Of the minority of men taking steroids who actually get blood tests, 99% of them get inaccurate assays.
Most doctors don't realize the importance of high sensitivity testing when it comes to men in general, and even more so in steroid users.
The difference between high sensitivity testing and what you have probably been getting in the past can be the entire reference range, or in some cases, it may even be detecting metabolites or analogs of other hormones.
This is not limited to just testosterone either.
Measuring Estradiol via Roche ECLIA (Electrochemiluminescence Immunoassay) instead of liquid chromatography with tandem mass spectrometry (LC/MS-MS) has similar limitations, as do other hormone tests with insufficient analytical sensitivity.
The Most Accurate Total Testosterone Blood Test The gold standard for accurately measuring total testosterone levels is high-performance liquid chromatography with tandem mass spectrometry (LC/MS-MS).
Recent studies have shown that the current assays used in total testosterone testing lack the required sensitivity to produce accurate results when working with very low concentrations.
This can be especially problematic when trying to accurately measure total testosterone levels in severely testosterone deficient men, normal or testosterone deficient women, and children.
In addition, these tests have proven via my own personal tests to detect synthetic anabolic androgenic steroids as testosterone.
This issue can be corrected by newer methods based on mass spectrometry.
The Most Accurate Free Testosterone Blood Test The gold standard for accurately measuring free testosterone levels is equilibrium dialysis.
Equilibrium ultrafiltration is also sufficient.
A comparison of results obtained via equilibrium dialysis and equilibrium ultrafiltration found that the two methods correlated closely (r = 0.97) [R].
Direct analog enzyme immunoassay (EIA) is inaccurate and has shown in my own personal tests to detect synthetic anabolic androgenic steroids as testosterone.
My Blood Test Results Comparing ECLIA And EIA Vs. LC/MS-MS And Equilibrium Ultrafiltration This is an example that very clearly shows how important high sensitivity testing can be.
I went in for a blood test during a Nandrolone-only experiment.
I had no Testosterone in my system whatsoever.
Expectedly, by assessing my Total Testosterone level via liquid chromatography with tandem mass spectrometry (LC/MS-MS) and my Free Testosterone level via equilibrium ultrafiltration, we can see that my Testosterone levels were crashed.
Both the total and the free were lower than a healthy female.
This is what you should see in your blood work if you’re on just Nandrolone.
The only Testosterone being produced in my body was indirectly via the trace amounts of androgens produced in my adrenal cortex, which is why the value wasn't completely bottomed out at 0.
I've mentioned many times the importance of getting high sensitivity testing done for hormone levels and how Nandrolone will register as Testosterone in primitive garbage blood tests.
This is another great example of this.
In addition to high sensitivity testing, I had the same blood tested using electrochemiluminescence immunoassay (ECLIA) for my Total Testosterone level, and direct analog enzyme immunoassay (EIA) for my Free Testosterone level.
These were the test results using the exact same blood sample with the terrible default assays that doctors will use to determine how to treat you, and that labs will give you in the majority of your blood work panels.
According to ECLIA and EIA, I had a normal Total Testosterone and Free Testosterone level.
This just one example of why getting accurate hormone testing is critical.
My Testosterone levels were actually in the gutter, but ECLIA and EIA couldn't even tell the difference between T