To Health With That! MTHFR Mutations‪.‬ Amy Neuzil

Doing a good detox protocol takes some preparation and some of the best preparation you can do is finding out if your genes are making detoxification harder for you somewhere. Some gene SNPs have the potential to make detox harder by interfering with phase two conjugation reactions. These include MTHFR, MTR, MTRR, GST, GPX, COMT, HNMT, UGT1A1, SULT genes, NAT1, and NAT2.
With each category of gene SNP, I will also give suggestions for improving that aspect of your phase two detoxification reactions.


00:00 - Intro
00:49 - Why SNPs matter and how to test
02:08 - Genes that affect methylation and how to help
02:46 - Genes that affect glutathione and how to help
03:38 - Genes that affect sulfation and how to help
04:20 - Genes that affect glucuronidation and how to help
05:52 - Genetic Rockstars walkthrough
07:42 - Genes that affect acetylation and how to help
08:11 - Amino acid conjugation

GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com

FREE COURSE: MTHFR Basics: https://to-health-with-that.teachable.com/p/mthfr-basics

WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min

GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/

WEBSITE: https://tohealthwiththat.com/


AFFILIATE LINKS:
I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you!

SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4
STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5
FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt
QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more


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Detox is amazing for your body, so why does it feel so awful? The great news is that symptoms of detoxification may be helpful in giving your signals about what is happening. We'll quickly review phases I - III of detoxification, why things can feel bad, where detoxification gets stuck, and how to plan for an easier detoxification.

00:00 - Intro
00:58 - 3 phases of detox
02:54 - detox uses energy and resources
04:24 - Four reasons why detox feels bad
06:31 - Plan ahead for easier detox
07:21 - Symptoms of detox

GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com

FREE COURSE: MTHFR Basics:
https://to-health-with-that.teachable.com/p/mthfr-basics

WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min

GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/

WEBSITE: https://tohealthwiththat.com/


AFFILIATE LINKS:
I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you!

SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4
STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5
FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt
QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more


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In the last episode, we discussed the fact that toxins come from food, air, water, personal care products, and pretty much everything we encounter. Detoxification is an ongoing process that is always at work in your body. Here are the basics about how detoxification happens, what resources your body needs, and why it sometimes feels yucky.

Detoxification happens in three phases. Phase one involves chemical reactions, mostly in the cytochrome P450 system. Phase two comprises conjugation reactions so that substances can be transported out of the tissues, and phase three is the active transport of these toxins out of your tissues and into waste material.

00:00 - intro
00:29 - Why Detox is easy to get wrong
01:19 - Three phases of detoxification
01:40 - Detoxification Phase one and cytochrome P450 system
02:31 - Genetic Rockstars quick walk-through
04:36 - Detoxification Phase two, conjugation reactions, and gene SNPS
05:15 - Phase three reactions and toxin transport
05:43 - You have to eliminate to detox
06:26 - Water and detox
06:50 - Limit toxin exposure
08:05 - Detox uses energy and nutrients
09:01 - Practitioner support and detox kits



GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com

FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics

WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min

GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/

WEBSITE: https://tohealthwiththat.com/


AFFILIATE LINKS:
I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you!

SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4
STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5
FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt
QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more


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Toxins are everywhere in modern life, and they have always been a normal part of life because they come from food, bacteria, mold, yeast, air, water, and the soil. Also, now, industrial and agricultural chemicals, the products we use on our skin, teeth, hair, and nails, and things we use to care for our homes like air fresheners, cleaning products, and that sort of thing.

Toxins are everywhere and they can accumulate in your system causing symptoms like fatigue, exhaustion, brain fog, weakness, poor memory, difficulty concentrating, skin outbreaks, constipation, and irritability.

Let's talk about where toxins come from and how toxins make you feel, and this will start our short mini-series on detoxifying.

00:00 - Intro
00:35 - Where toxins come from
01:24 - Detox is always happening
02:06 - Why toxins cause fatigue
02:48 - Toxicity is a vague term
03:39 - General toxic symptoms
04:00 - Voluntary toxins
04:42 - Drugs and supplements
06:36 - Surgical toxins
07:05 - Toxins and genes
08:20 - Cytochrome P-450
09:11 - What is coming up in the toxin mini-series

GENETIC ROCKSTARS (an MTHFR community): https://community.tohealthwiththat.com

FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics

WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min

GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/

WEBSITE: https://tohealthwiththat.com/


AFFILIATE LINKS:
I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you!

SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4
STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5
FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt
QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more


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Problems with oxygenation can affect your sleep quality and quantity, leaving you feeling tired, or like you slept but woke up as tired as you were the night before, or just plain exhausted.
Iron deficiency and carbon monoxide poisoning are both oxygen problems, not that we think of them that way, but many oxygen problems are more subtle. The classic oxygen problem overnight is sleep apnea, which causes you to wake up through the night becuase you stop breathing momentarily.
Mouth breathing at night also impairs oxygen and leads to fatigue, low energy, and a poor night's sleep. My favorite solution to this problem is mouth taping.

00:00 - Intro
00:40 - Iron deficiency and carbon monoxide poisoning
01:55 - Sleep Apnea
02:21- Types of Sleep Apnea
03:08 - Sleep apnea treatment
03:36 - Sinuses and fatigue
04:07 - Mouth breathing and fatigue
05:15 - Why mouth breathing causes fatigue
05:45 - Three differences between breathing through your nose and mouth
07:05 - Fix mouth breathing with mouth taping

GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com

FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics

WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min

GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/

WEBSITE: https://tohealthwiththat.com/


AFFILIATE LINKS:
I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you!

SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4
STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5
FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt
QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more


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Sex hormones have a lot to do with how energetic you feel, or how sleepy, or how grumpy. So, let's talk about how estrogen ties into sleep, weight, and metabolism. How progesterone helps insomnia and gets stolen by stress hormones. Also, how testosterone is a feel-good chemical. We'll also talk about xenoestrogens, which come from outside your body, and how to reduce estrogen, boost progesterone and testosterone, and generally find hormone balance.

00:00 - intro
00:29 - What sex hormones do
00:59 - Estrogen and metabolism
01:40 - Estrogen dominance
02:03 - Xenoestrogens (estrogen from chemicals)
02:25 - Two ways to manage estrogen levels
02:30 - Avoid estrogen from chemicals
03:43 - Detoxify estrogen better
03:53 - Estrogen detox needs good methylation
05:00 - Progesterone, sleep, and stress
06:25 - Testosterone and wellbeing
07:04 - High estrogen causes low testosterone
07:48 - Men need weight bearing exercise
08:02 - Losing weight leads to estrogen spikes
08:20 - Supplements for Testosterone
08:38 - Energy changes in menstrual cycle
09:26 - The bottom line

GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com

FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics

WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min

GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/

WEBSITE: https://tohealthwiththat.com/


AFFILIATE LINKS:
I get a small profit when you choose to buy from these links, so thank you!

SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4
STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5
FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt
QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more


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Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message