163 episodios

Pharmacy to Dose: The Critical Care Podcast discusses critical care and its pharmacotherapy in a fun and entertaining manner. Each episode features a special guest, a subject matter expert, talking with host Nick Peters.

Pharmacy to Dose: The Critical Care Podcast Nick Peters

    • Salud y forma física

Pharmacy to Dose: The Critical Care Podcast discusses critical care and its pharmacotherapy in a fun and entertaining manner. Each episode features a special guest, a subject matter expert, talking with host Nick Peters.

    ANNEXa-I Deep Dive: Part I

    ANNEXa-I Deep Dive: Part I

    ANNEXa-I Deep Dive Part I
    Special Guests: Scott Dietrich, PharmD, BCCCP
    Brian Gilbert, PharmD, MBA, BCCCP, FCCM, FNCS
    Todd Miano, PharmD, PhD, FCCM
     
    05:40 – Brief ANNEXa-I study overview
    20:40 –Primary composite outcome
    26:40 – Anti-FXa levels
    30:45 – Statistics/methodology questions
     
    Reference List: https://pharmacytodose.com/wp-content/uploads/2024/06/annexai-deep-dive-part-i-references.pdf
     
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    • 54 min
    January 2024 Literature Review Series

    January 2024 Literature Review Series

    Literature Review Series
    January 2024
    Special Guests: Haley Torr, PharmD
    Nick Tran, PharmD
     
    06:55 – Featured Articles
    32:55 – PAD-IS articles
    37:10 – Cardiology articles
    46:00 – Heme articles
    51:40 – Potpourri articles
    60:05 – Pharmacist-featured articles
    67:30 – Sweet Emotion articles
     
    Reference List: https://pharmacytodose.com/wp-content/uploads/2024/06/jan-2024-lrs-references.pdf
     
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    • 1h 15 min
    Trial of the Week: PROWESS-SHOCK

    Trial of the Week: PROWESS-SHOCK

    Trial of the Week: PROWESS-SHOCK
    Special Guest: Paul Szumita, PharmD, FCCM, FASHP, BCCCP, BCPS @paulszumita
     
    03:30 – Background studies/Setting the scene
    30:25 – PROWESS-SHOCK discussion/Where are we now
     
    Paul Szumita joins to highlight a June Trial of the Week “Drotrecogin alfa (activated) in adults with septic shock” published in the New England Journal of Medicine in 2012.
    To fully understand the discussion regarding drotrecogin alfa, Paul and I review the mechanism of action and its proposed action in the treatment of sepsis. Then we review earlier studies and the controversy behind the FDA approval process. Finally, we go into detail on what Clinical Pharmacists were tasked with doing at the time based on treatment protocols or hospital restrictions.
    Then we dive into the Trial of the Week, discussing the study design and results. What was the mood in ICUs and Pharmacy Departments after this publication? How much did our sepsis care improve from PROWESS to PROWESS-SHOCK? What lessons did we learn with the Xigris FDA approval process? Is there a patient population that could still benefit from drotrecogin alfa treatment? Plus, trial fun facts, issues with calculating APACHE II scores, and so much more.
    Reference list: https://pharmacytodose.com/wp-content/uploads/2024/06/prowess-shock-trial-of-the-week-references.pdf
     
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    • 1h
    2023 Year-In-Review Literature Review Series

    2023 Year-In-Review Literature Review Series

    Literature Review Series
    2023 Year-In-Review
    Special Guests: Jacquelyn Crawford, PharmD @jacuronium
    Kathleen Hartman, PharmD @HartKate8
     
    04:30 – Neurology
    11:05 – Cardiology
    18:50 – Cardiac Arrest
    26:30 – Pulmonary
    35:00 – Sepsis
    44:05 – Endocrine/Renal
    52:30 – Trauma
    61:05 – Infectious Diseases
     
    Reference List: https://pharmacytodose.com/wp-content/uploads/2024/06/yir-2023-lrs-references.pdf
     
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    • 1h 15 min
    Trial of the Week: Ketamine for EM Agitation

    Trial of the Week: Ketamine for EM Agitation

    Trial of the Week: Ketamine for EM Agitation
    Special Guest: Justin Lin, PharmD, BCPS, BCCCP @jjlinpharmd
     
    Justin Lin joins to review the May Trial of the Week “Efficacy of ketamine for initial control of acute agitation in the emergency department: a randomized study” published in the American Journal of Emergency Medicine in 2021.
    We set the scene by discussing how this research idea started, review the classic agitation presentation at his institution, and highlight evidence comparing pharmacotherapy treatment options prior to this study. Then we dive into the Trial of the Week, discussing the study design and results. What was the biggest pushback from providers or the IRB? Any unique education strategies? Would results stay the same with increased IV push administration? What would the comparator arm be if this study was replicated today? Plus, the most challenging part of this project, Justin’s favorite agent, and so much more.
     
    Reference list: https://pharmacytodose.com/wp-content/uploads/2024/05/ketamine-for-em-agitation-trial-of-the-week-references.pdf
     
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    • 45 min
    Sanford Guide Q&A

    Sanford Guide Q&A

    Sanford Guide Q&A
    Special Guest: Doug Black, PharmD
     
    04:40 – Doug’s background/Sanford guide introduction
    14:20 – Print v. digital guide/included content
    34:35 – Tables/tools highlights
    41:55 – Doug’s favorites/conclusions
     
    Sanford Guide Website: https://web.sanfordguide.com/
     
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    • 1h 3 min

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