21分
AI identifies gene interactions to speed up search for treatment targets Nature Podcast
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- 科学
In this episode:
00:46 An AI that predicts gene interactionsMapping the network of genes that control cellular processes can be difficult to do when gene-expression data is sparse, such as in rare diseases or those affecting tissues that are hard to clinically sample. To overcome this, a team has developed an artificial intelligence system trained on a large, general dataset, and used it to make predictions about gene interactions in data-limited situations. As a test-case they look at the heart condition cardiomyopathy, and show that the system can identify potential interactions that could represent new therapeutic targets.
Research article: Theodoris et al.
09:08 Research HighlightsMicrobes that can break down persistent ‘forever chemicals’, and why intermolecular distances are the key to keeping gummy sweets chewy.
Research Highlight: Microbes take the ‘forever’ out of ‘forever chemicals’
Research Highlight: Better gummy sweets are within reach, thanks to physics
12:06 Briefing ChatWe discuss some highlights from the Nature Briefing. This time, how chronic stress can inflame the gut, and understanding how rocket launches might impact wildlife.
Nature News: Chronic stress can inflame the gut — now scientists know why
Nature News: Does the roar of rocket launches harm wildlife? These scientists seek answers
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Hosted on Acast. See acast.com/privacy for more information.
In this episode:
00:46 An AI that predicts gene interactionsMapping the network of genes that control cellular processes can be difficult to do when gene-expression data is sparse, such as in rare diseases or those affecting tissues that are hard to clinically sample. To overcome this, a team has developed an artificial intelligence system trained on a large, general dataset, and used it to make predictions about gene interactions in data-limited situations. As a test-case they look at the heart condition cardiomyopathy, and show that the system can identify potential interactions that could represent new therapeutic targets.
Research article: Theodoris et al.
09:08 Research HighlightsMicrobes that can break down persistent ‘forever chemicals’, and why intermolecular distances are the key to keeping gummy sweets chewy.
Research Highlight: Microbes take the ‘forever’ out of ‘forever chemicals’
Research Highlight: Better gummy sweets are within reach, thanks to physics
12:06 Briefing ChatWe discuss some highlights from the Nature Briefing. This time, how chronic stress can inflame the gut, and understanding how rocket launches might impact wildlife.
Nature News: Chronic stress can inflame the gut — now scientists know why
Nature News: Does the roar of rocket launches harm wildlife? These scientists seek answers
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Hosted on Acast. See acast.com/privacy for more information.
21分