Ask Dr. Mia: Conversations on Aging Well Dr. Mia

For the last episode of season 2, Dr. Mia talks about lecanemab, a monoclonal antibody against amyloid, results since the show's most popular episode on lecanemab released on 10/7/2022.

Lecanemab or Clarity AD clinical trial results in New England Journal of Medicine (NEJM)
Death related to lecanemab, reported in Science, related to Cerebral Amyloid Angiopathy
Donanemab press release by Lilly

Key points:
1) Aducanumab approval process eroded public's trust and careful screening for patients for real-world implementation of lecanemab is needed to build back trust.
2) Actual number of patients eligible for lecanemab will be much smaller than the total number of persons living with Alzheimer's disease in the country: studies estimate anywhere from 1% to 12% of patients seen in real world clinics.  
3) Our healthcare infrastructure is not ready for early, timely, and accurate detection of Alzheimer's disease and tracking patients on monoclonal antibodies. 
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Email: ask@miayangmd.com
Opinions expressed are exclusive of Dr. Mia Yang and not reflective of her or guest speaker's employers or funders.

In this episode, Dr. Mia talks with Dr. Trey Bateman about Lewy Body dementia, unique challenges in diagnosis, different treatment options compared to Alzheimer's dementia, and his research on Mild Behavioral Impairment.

Dr. James (Trey) Bateman is a behavioral neurologist at Wake Forest University School of Medicine and the Salisbury Veterans Affairs Medical Center. His clinical care is spread across both Wake Forest and the Salisbury VA, where he focuses on the evaluation and care of people with neurodegenerative conditions, especially those with prominent neuropsychiatric symptoms. His research is focused on the role of chronic psychosocial stress and dementia risk and the role of early neuropsychiatric symptoms in the prodromal stages of neurodegenerative cognitive disorders.

More information on Dementia with Lewy Bodies

Anticholinergic medications based on the 2023 American Geriatrics Society Beers list of medications to use with caution in older adults

Support groups specifically for caregivers and persons living with Lewy Body Dementia

 
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Support the showTranscripts on www.miayangmd.com. Transcripts are automatically generated and may contain minor inaccuracies.
Email: ask@miayangmd.com
Opinions expressed are exclusive of Dr. Mia Yang and not reflective of her or guest speaker's employers or funders.

With the recent news of Bruce Willis' diagnosis of frontotemporal dementia, I talk with Dr. Halima Amjad about her own personal journey with her late father's FTD diagnosis as well as her professional role in dementia care and research.

Dr. Halima Amjad is an assistant professor of medicine at the Johns Hopkins University School of Medicine. Her career as a geriatrician and health services researcher centers around people living with dementia. She cares for patients at the Johns Hopkins Memory and Alzheimer’s Treatment Center. Her research focuses on medical care challenges in dementia, including underdiagnosis, hospitalization, and primary care support. Her advocacy work includes serving on the Board of the Association for Frontotemporal Degeneration and as chair of the Maryland Virginia I. Jones Alzheimer’s disease and related dementias council.

The Association for Frontotemporal Degeneration
Music & disclaimer
Support the showTranscripts on www.miayangmd.com. Transcripts are automatically generated and may contain minor inaccuracies.
Email: ask@miayangmd.com
Opinions expressed are exclusive of Dr. Mia Yang and not reflective of her or guest speaker's employers or funders.

Sleep, everyone wants it or better versions of it. Dr. Mia talks with Dr. Jaime Hughes about sleep for older adults.
Jaime Hughes is an Assistant Professor at Wake Forest University School of Medicine, Department of Implementation Science and Section on Gerontology and Geriatric Medicine. As an implementation scientist, Dr. Hughes focuses on how to spread programs that work into different settings, including healthcare clinics and community-based services. She has a particular interest in programs to help older adults sleep well and move more. Her work is supported by a team of public health and clinical researchers who comprise the AMAZE Research Team – Atrium Health Wake Forest Baptist Movement And Zzz’s for Everyone. Dr. Hughes received her PhD from UNC at Chapel Hill and her MPH and MSW from University of Michigan.

Interested in learning more about research opportunities in sleep and aging? Email Dr. Hughes' team at AMAZEResearchTeam@wakehealth.edu. 
 Other resources:
Sleep and Aging
Healthy Sleep Habits
Cognitive Behavioral Therapy for Insomnia
 
Support the showTranscripts on www.miayangmd.com. Transcripts are automatically generated and may contain minor inaccuracies.
Email: ask@miayangmd.com
Opinions expressed are exclusive of Dr. Mia Yang and not reflective of her or guest speaker's employers or funders.

Dr. Mia talks with Dr. Rosanne Leipzig, a trailblazer in transforming the way we approach aging individually and as a society.  In her 40+ year career, she has treated thousands of patients and trained hundreds of doctors and practitioners in all specialties of medicine.  She is the Gerald and May Ellen Ritter Professor and Vice Chair, Emerita of the Brookdale Department of Geriatrics and Palliative Medicine at the Icahn School of Medicine at Mount Sinai in New York City.  We talked about her new book, Honest Aging: An Insider’s Guide to the Second Half of Life.

* Rosanne's inspiration for writing the book
* Ageism, both external and internal
* What is normal as we age and how to talk to loved ones about it
* How old is too old to hold public office
* Sex! No, older adults don't just stop having sex when they get to a certain age

You can purchase Honest Aging book from the publisher, on GoodReads, Bookshop, and Amazon.
Support the showTranscripts on www.miayangmd.com. Transcripts are automatically generated and may contain minor inaccuracies.
Email: ask@miayangmd.com
Opinions expressed are exclusive of Dr. Mia Yang and not reflective of her or guest speaker's employers or funders.

Dr. Mia talks with Frances Hall and Bob Cain about the unique needs of adult children who are caring for their aging parents and how their organization Adult Children of Aging Parents (ACAP) helps. Frances Hall is the founder of ACAP, a 501(c)(3) non-profit organization providing information, resources, and community for adult children caring for their aging parents and themselves. Bob Cain is a Chapter Coordinator for the Winston-Salem NC chapter of ACAP and Vice President of Marketing for Piedmont Home Care. 


We talked about why the word "caregiver" is notably missing from ACAP's name. ACAPCommunity Podcast; specifically sibling dynamics episode with Alyssa Botte (Dec 20, 2020). Videos from various chapters on YouTube. Locating via zip code on Eldercare Locator your Area Agency on Aging's Family Caregiver Specialist. Piedmont Triad Area contacts here. Email:  info@ACAPcommunity.org
Toll-free 1-877-599-ACAP (1-877-599-2227)

This episode was edited and transcribed by Bear Beat Productions. 
Support the showTranscripts on www.miayangmd.com. Transcripts are automatically generated and may contain minor inaccuracies.
Email: ask@miayangmd.com
Opinions expressed are exclusive of Dr. Mia Yang and not reflective of her or guest speaker's employers or funders.