17 episodes

The Huberman Lab Podcast discusses Neuroscience: how our brain and its connections with the organs of our body controls our perceptions, our behaviors, and our health.

We also discuss existing and emerging tools for measuring and changing how our nervous system works.

Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration and neuroplasticity, and brain states such as stress, focus, fear, and optimal performance.

For more than 20 years, Dr. Huberman has consistently published original research findings and review articles in top-level peer-reviewed journals including Nature, Science, Cell, Neuron, and Current Biology.

He is a regular member of several National Institutes of Health review panels, and a Fellow of the McKnight Foundation and the Pew Charitable Trusts.

Dr. Huberman regularly consults for technology development companies, professional athletic organizations, and for various units of U.S. and Canadian Special Operations.

Huberman Lab Dr. Andrew Huberman

    • Health & Fitness
    • 5.0 • 2.1K Ratings

The Huberman Lab Podcast discusses Neuroscience: how our brain and its connections with the organs of our body controls our perceptions, our behaviors, and our health.

We also discuss existing and emerging tools for measuring and changing how our nervous system works.

Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration and neuroplasticity, and brain states such as stress, focus, fear, and optimal performance.

For more than 20 years, Dr. Huberman has consistently published original research findings and review articles in top-level peer-reviewed journals including Nature, Science, Cell, Neuron, and Current Biology.

He is a regular member of several National Institutes of Health review panels, and a Fellow of the McKnight Foundation and the Pew Charitable Trusts.

Dr. Huberman regularly consults for technology development companies, professional athletic organizations, and for various units of U.S. and Canadian Special Operations.

    How Hormones Control Hunger, Eating & Satiety | Episode 16

    How Hormones Control Hunger, Eating & Satiety | Episode 16

    This episode I discuss how hormones from our gut, liver, pancreas and brain control our appetite-- and the specific tools we can use to adjust those hormones in order to achieve specific goals. I explain the brain areas that control our desire to eat, and our desire to stop eating. I discuss a hormone we all can make that is regulated by UV-rays from sunlight that reduces our appetite. I also explain that when we eat controls our appetite and not the other way around (and how to leverage that fact). I describe how we are basically always eating until we reach a threshold level of fatty acids and amino acids in our gut and the factors that can alter that signaling and make us eat far more than we need. I also explain how insulin, glucose and glucagon work, why cholesterol is so key for ovary, adrenal, liver and testes function and how the ketogenic diet impacts glucose and thyroid levels. As always, I describe many tools: specific supplements, prescription compounds, specific types (and timing) of exercise to regulate hormones, specific timing and types of eating, ways to reduce sugar cravings by triggering release of the hormone CCK, and more.
    Note: A future episode will cover Thyroid hormone. Also, I mis-spoke when explaining POMC neurons. I said “P-M-O-C” but should have said “POMC”. Apologies. The name I gave for what POMC is, however, was correct: "proopiomelanocortin".
    Thank you to our sponsors:
    InsideTracker - http://insidetracker.com/huberman Athletic Greens - http://athleticgreens.com/huberman Munk Pack - http://munkpack.com - Code: huberman Our Patreon page:
    https://www.patreon.com/andrewhuberman Supplements from Thorne:
    http://www.thorne.com/u/huberman Social:
    Instagram - https://www.instagram.com/hubermanlab Twitter - https://twitter.com/hubermanlab Links:
    Dr. Lustig’s Lecture - https://www.youtube.com/watch?v=nxyxcTZccsE Paper In Cell Metabolism On Processed Food Effects - https://doi.org/10.1016/j.cmet.2019.05.008 Timestamps:
    00:00:00 Introduction 00:06:59 Hunger: Neural & Hormonal Control 00:08:32 Chewing & Hunger 00:11:05 Siamese Rats Reveal the Importance of Hormones In Hunger 00:13:08 Neurons That Powerfully Control Hunger by Releasing Specific Hormones 00:16:28 Anorexia & Extreme Overeating 00:16:57 Why Sunlight Suppresses Hunger: a-Melanocyte Stimulating Hormone (a -MSH) 00:20:03 Blue-blockers, Injecting a-MSH: Instant Tan & Priapism 00:22:30 Ghrelin: A Hormone That Determines When You Get Hungry, & That You Can Control 00:24:40 Meal Timing Determines Hunger, Not the Other Way Around 00:27:20 Satchin Panda, Circadian Eating & Intermittent(ish) Fasting 00:29:35 How To Rationally Adjust Meal Schedules: The 45min Per Day Rule 00:33:02 CCK (Cholecystokinin): A Hormone In Your Gut That Says “No Mas!” 00:34:55 Eating For Amino Acids, Fatty Acids & Sugar 00:39:05 L-Glutamine: Stimulates the Immune System & Reduces Sugar Cravings 00:43:42 Things To Avoid: Emulsifiers; Alter Gut Mucosa & Nutrient Sensing 00:49:32 “A Calorie Is NOT A Calorie” After All 00:52:36 Insulin & Glucose: Hyperglycemia, Euglycemia, & Hypogylcemia 00:56:12 The Order Your Eat Foods Matters: Managing Your Blood Glucose & Glucagon 01:02:40 Movement, Exercise & GLUT-4 01:04:50 Why Sugar Stimulates Your Appetite 01:05:40 Keeping Blood Sugar Stable With Specific Exercises, The Power Of Insulin Sensitivity 01:07:55 High-Intensity Exercise, Glycogen & Metabolism 01:10:28 Cholesterol, HDL, LDL & Glucose Management: Ovaries, Testes, Liver, Adrenals 01:15:00 Prescription Compounds That Reduce Blood Glucose: Metformin 01:16:45 Berberine: A Potent Glucose Buffer That Also Adjusts Cholesterol Levels, Canker Sores 01:22:05 Chromium, L-Carnitine, Ginseng, Caffeine, Magnesium, Stevia, Vitamin B3, & Zinc 01:24:34 Acids: Vinegar, Lemons & Limes & False Alkalinity 01:26:40 Ketogenic Diets (In Brief): Effects On Blood Glucose,

    • 1 hr 39 min
    How to Optimize Testosterone & Estrogen | Episode 15

    How to Optimize Testosterone & Estrogen | Episode 15

    This episode I discuss the hormones testosterone and estrogen and how they impact the brain, body, and behavior at ages after puberty. I also discuss how various behaviors such as exercise (resistance and endurance training) and sex, or observing sex impact these hormones and their levels. I ask: "what specifically is it about such activities that impacts testosterone and estrogen?"; the resounding theme is that when our nervous system is activated in particular ways it drives our endocrine system and vascular system to activate or repress certain hormone networks in predictable ways. I also discuss peer-reviewed studies and protocols addressing (at a mechanistic level) how light, cold and heat, and respiration (breathing) can positively or negatively impact testosterone and estrogen. And we discuss specific supplements and compounds that peer-reviewed studies illustrate can adjust testosterone and estrogen levels: by changing their binding to other proteins, by raising them directly, or by changing other hormones released from the brain and pituitary. I discuss optimization in the normal reference ranges for these hormones, and I discuss pheromones, apnea, menstrual cycles, menopause and andropause. As always a mix of basic science, biological mechanisms and tools and protocols are discussed.
    **Note: Future episodes will focus on the science of prescription hormone replacement therapies, the science of hormone-based birth control and the role of testosterone, estrogen and other compounds in fertility, athletic performance and recovery.
     
    Thank you to our sponsors:
    Four Sigmatic - http://foursigmatic.com/huberman Blinkist - http://blinkist.com/huberman Theragun - http://theragun.com/huberman  
    Bloodwork sponsor:
    InsideTracker - http://insidetracker.com/huberman  
    Our Patreon page:
    https://www.patreon.com/andrewhuberman  
    Supplements from Thorne:
    http://www.thorne.com/u/huberman  
    Social:
    Instagram - https://www.instagram.com/hubermanlab Twitter - https://twitter.com/hubermanlab  
    References:
    http://examine.com “Behavioral Endocrinology” by Nelson and Kriegsfeld 5th Ed. Timestamps:
    00:00:00 Introduction 00:05:50 Hormone Optimization 00:07:00 Salutogenesis: A Powerful Way to Conceptualize Health 00:10:03 Estrogen and Testosterone: Sources, Levels & Ratios 00:15:46 The Power of Competition, Plus: Anxiety, Persistence & Dopamine 00:20:58 Testosterone & Libido Pre-Ovulation 00:21:48 Estrogen & Sexual Receptivity; Libido In Males 00:23:10 How Sex Behavior Impacts Testosterone: Observing vs. Actual vs. Abstinence 00:26:46 Testosterone & Prolactin: Sex Seeking vs Pair Bonding 00:27:30 DHEA (dehydroepiandrosterone): Effects on Levels/Ratios 00:28:45 Behaviors That Decrease Testosterone (& Cortisol): Parenting & Prolactin 00:31:24 How Illness Impacts Testosterone & Estrogen: Cytokines, e.g., IL-6 00:33:20 How Exactly Do Behaviors Change Hormones? 00:34:18 Pheromones: Miscarriage, Menstrual Cycles, Puberty Onset, & Mate Recognition 00:43:33 Apnea: A Powerful Bi-Directional Influence On Estrogen & Testosterone 00:47:44 Mouth vs. Nose Breathing & Hormone Levels: Effects Via Sleep and Direct Effects 00:51:11 How Sleep Adjusts Cortisol/Testosterone and Cortisol/Estrogen Ratios 00:53:49 02:CO2 Ratios, Nasal Breathing During Exercise 00:56:30 Light Viewing Patterns & Hormones: Dopamine, GnRH 00:57:44 Spring Fever: Tyrosinase, Hair Color, Mating Frequency 01:04:39 Specificity of Hormone Effects 01:06:03 Temperature: Cold & Hot Gonads 01:14:10 How To Exercise: Types, Effort Level, Sequencing 01:21:42 Cardio/Endurance vs. Resistance Training (First or Last?) Yes, It Matters 01:24:41 Estrogen & Menopause: Compounds That May Ameliorate/Reverse Symptoms 01:33:18 Nutrients That Optimize The Foundation For Hormones 01:36:00 Opioids as Severe Hormone Disruptors 01:37:23 Testes, Antlers & Ovaries 01:38:50 Creatine

    • 2 hr 2 min
    The Science of Sexual Development | Episode 14

    The Science of Sexual Development | Episode 14

    In this episode I discuss how hormones such as testosterone and estrogen and their derivatives impact the early development of the brain and body and their maturation. I review published data on environmental factors shown to powerfully alter hormone pathways in animals and humans and the effects of cannabis, alcohol and cell phones on testes, sperm, ovaries and hormones. I describe the predictable relationship between genes, beard growth and balding patterns, and the importance of estrogen for brain development in people of all chromosomal sexes. Finally, I discuss how the hormones we are exposed to in the womb shape the relative length of our finger digits, the sounds our ears make (yes you read that correctly), and how those correlate with people's self-reports of their sexual preferences. As always, basic information and tools are discussed.
     
    Thank you to our sponsors:
    InsideTracker - https://insidetracker.com/huberman Helix Sleep - https://helixsleep.com/huberman Athletic Greens - https://athleticgreens.com/huberman  
    Our Patreon page:
    https://www.patreon.com/andrewhuberman  
    Supplements from Thorne:
    http://www.thorne.com/u/huberman  
    Social:
    Instagram - https://www.instagram.com/hubermanlab Twitter - https://twitter.com/hubermanlab  
    Links:
    Mood Meter: https://moodmeterapp.com/ NSDR: https://www.youtube.com/watch?v=pL02HRFk2vo Cell Phones & Hormones: https://pubmed.ncbi.nlm.nih.gov/22138021/ Finger Length Ratios & Hormones/Sexual Orientation: https://www.nature.com/articles/35006555 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940503/ LeVay Study in Science Magazine on Sexual Orientation Brain Dimorphism: https://science.sciencemag.org/content/253/5023/1034  
    Timestamps below.
    00:00:00 Introduction 00:06:47 Announcement: Mood Meter App Works Again 00:08:00 Maximizing Learning from the Podcast 00:10:00 New Non-Sleep Deep Rest Protocol, Spanish Subtitles 00:11:35 Sexual Differentiation: Hormones, Neurons & Behavior 00:14:15 Hormones Basics 00:15:26 Sperm Meets Egg, Chromosomal Sex, Gonadal Sex, 00:17:50 Y Chromosome Inhibition of Feminization 00:19:00 Placenta Is An Endocrine (Hormone-Producing) Organ, Adrenal Testosterone 00:19:45 Hormonal Sex, Morphological Sex 00:21:04 Hormones Fast & Slow, Sex Steroids Can Turn On Genes 00:23:06 Masculinization, Feminization, Demasculinization, Defeminization 00:23:42 Primary Sexual Characteristics: DHT Drives Penis Development 00:27:03 Secondary Sexual Characteristics 00:27:43 Penis Sprouting: Guevedoces 00:31:25 Estrogen, NOT Testosterone, Masculinizes The Brain 00:33:15 Breast Development In Males: Aromatase; Puberty, & Steroids in Athletes 00:34:50 Estrogen Powerfully Controls Brain Development In All Individuals 00:35:19 Avoiding Hormonal Disruption In Children & Adults: Specific Oils, Creams, Etc. 00:39:00 Environmental Endocrine Disruptors, Sperm Count Decline, Vincloziline 00:44:20 Androgen Insensitivity Syndrome: Hormones Need Receptors, SARMS 00:48:41 Estrogen Establishes “Masculine” Brain Circuits, Testosterone 00:49:42 Cannabis, Alcohol: In Babies, Puberty & Adults 00:56:25 Cell Phone Technology: Effects On Hormones, Ovaries, & Testicles 01:02:33 Beards & Baldness Patterns Around the World, DHT, 5-alpha-reductase 01:06:39 Creatine & DHT/Hair Loss 01:08:20 Predicting Aging Rates By Pubertal Rates 01:10:04 Hyenas, Baseball, & Jumbo Clitorises: Androstenedione 01:14:26 Intersex Moles 01:15:40 Marijuana Plants, Pollens: Plant-To-Animal “Warfare” 01:20:08 Finger Length Ratios, Prenatal Hormone Exposure & Sexual Orientation 01:29:13 Brain Dimorphisms with Sexual Orientation 01:32:00 “Older Brother Effects”: Male Fetuses Might Change Mothers & Subsequent Brothers 01:35:06 The Path Forward & A Warning 01:35:55 Support & Your Questions  
    Please note that The Huberman Lab Podcast is distinct from Dr. Huberman's teaching and research

    • 1 hr 38 min
    The Science of Emotions & Relationships | Episode 13

    The Science of Emotions & Relationships | Episode 13

    In this episode I discuss the biology of emotions and moods in the context of relationships. I focus on the science of how early infant-caregiver attachment, combined with adolescence and puberty shape our adult patterns of attachment. I explain the three universal aspects of emotions, the reality of right-brain versus left-brain personalities, and how the roots of adult attachment are also grounded in specific aspects of puberty. I review what factors determine when puberty starts and ends, and the role of oxytocin and other chemicals in controlling how we perceive and remember others. As always, I refer to various practical tools including new tools for understanding and predicting our emotions before they occur, and neurochemicals that shape human connection.
     
    Thank you to our sponsors:
    InsideTracker - https://insidetracker.com/huberman ExpressVPN - http://expressvpn.com/huberman Magic Spoon - http://magicspoon.com/huberman Our Patreon page:
    https://www.patreon.com/andrewhuberman Supplements from Thorne:
    http://www.thorne.com/u/huberman Links:
    NSDR - https://www.youtube.com/watch?v=pL02HRFk2vo Mood Meter App - https://moodmeterapp.com/ Adolescence and The Brain - https://www.nature.com/articles/nature25770 Vagus and Depression - https://www.newyorker.com/magazine/2015/05/18/lighting-the-brain  
    Timestamps below.
    00:00:00 Introduction 00:05:10 Announcing New Cost-Free Resources: Captions, NSDR Link 00:07:40 Emotions: Subjective Yet Tractable 00:10:53 To Understand Your Emotions: Look At Infancy & Puberty 00:15:21 Your First Feeling Was Anxiety 00:17:36 What Are “Healthy Emotions”? 00:19:03 Digital Tool For Predicting Your Emotions: Mood Meter App 00:21:08 The Architecture Of A Feeling: (At Least) 3 Key Questions To Ask Yourself 00:24:00 You Are An Infant: Bonds & Predictions 00:27:57 Attachment Style Hinges On How You Handle Disappointment 00:32:40 “Glue Points” Of Emotional Bonds: Gaze, Voice, Affect, Touch, (& Written) 00:36:34 “Emotional Health”: Awareness of the Interoceptive-Exteroceptive Dynamic 00:37:50 An Exercise: Controlling Interoceptive-Exteroceptive Bias 00:42:19 Getting Out Of Your Head: The Attentional Aperture 00:46:59 Puberty: Biology & Emotions On Deliberate Overdrive 00:47:58 Bodyfat & Puberty: The Leptin Connection 00:50:34 Pheromones: Mates, Timing Puberty, Spontaneous Miscarriage 00:54:37 Kisspeptin: Robust Trigger Of Puberty & Performance Enhancing Agent 00:58:26 Neuroplasticity Of Emotions: Becoming Specialists & Testing Emotional Bonds 01:00:25 Testing Driving Brain Circuits For Emotion: Dispersal 01:07:48 Science-Based Recommendations for Adolescents and Teens: The Autonomy Buffet 01:11:05 “Right-Brain Versus Left-Brain People”: Facts Versus Lies 01:14:18 Left Brain = Language, Right Brain = Spatial Awareness 01:16:15 How To Recognize “Right Brain Activity” In Speech: Prosody 01:18:32 Oxytocin: The Molecule of Synchronizing States 01:20:09 Mirror Neurons: Are Not For “Empathy”, Maybe For Predicting Behavior 01:23:00 Promoting Trust & Monogamy 01:27:00 Ways To Increase Oxytocin 01:28:34 Vasopressin: Aphrodisiac, Non-Monogamy and Anti-Bed-Wetting Qualities 01:30:43 Bonding Bodies, Not Just Minds: Vagus Nerve, Depression Relief Via the Body 01:35:18 A Powerful Tool For Enhancing Range & Depth of Emotional Experience 01:30:43 MDMA and Other Psychedelic Compounds: Building A Framework 01:38:54 Roundup, Various Forms of Support  
    Please note that The Huberman Lab Podcast is distinct from Dr. Huberman's teaching and research roles at Stanford University School of Medicine. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Huberman Lab Podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
    [Title Card Photo Credit:

    • 1 hr 41 min
    How To Increase Motivation & Drive | Episode 12

    How To Increase Motivation & Drive | Episode 12

    This episode explains the science of motivation and drive. I describe how dopamine-- a chemical we all make in our brain, underlies our desire for and pursuit of our goals, as well as our capacity to move and experience pleasure. I describe how we can leverage specific behaviors, reward schedules and dopamine-prolactin balance to help ensure we can maintain motivation and capacity for pleasure over the long term. I also discuss dopamine in the context of ADHD, craving and addiction, and some absolutely amazing results about specificity of drug effects based purely on belief.
    Thank you to our sponsors:
    Athletic Greens - https://athleticgreens.com/huberman Headspace - http://headspace.com/specialoffer Magic Spoon - http://magicspoon.com/huberman Our Patreon page:
    https://www.patreon.com/andrewhuberman Supplements from Thorne:
    http://www.thorne.com/u/huberman Link to study:
    Effects of expectation on specificity of stimulant effects: https://pubmed.ncbi.nlm.nih.gov/33734725/ Timestamps below.
    00:00:00 Introduction 00:04:22 Announcement: Spanish Subtitles 00:05:06 Emotions, Addiction & Mindset 00:06:22 Motivation & Movement: The Dopamine Connection 00:07:29 A Double-Edged Dopamine Blade 00:08:56 Dopamine Fundamentals: Precursor to Adrenalin 00:10:15 The Reward Pathway: An Accelerator & A Brake 00:12:10 Motivation= Pleasure Plus Pain 00:14:14 The Dopamine Staircase: Food, Sex, Nicotine, Cocaine, Amphetamine 00:16:15 Subjective Control of Dopamine Release 00:17:40 Social Media and Video Games 00:18:15 Addiction & Dopamine: Progressively Diminishing Returns 00:18:48 Novelty, Sensation-Seeking & Anticipation 00:20:15 Craving: Part Pain, Part Pleasure & Pain Always Prevails 00:23:11 Desire Scales With Pain: The Yearning Function 00:24:43 The Croissant Craving Circuit 00:25:45 “Here and Now” Molecules: Serotonin, Bliss & Raphe Nucleus 00:26:26 In Your Skin Or Out In the World 00:27:25 Cannabinoids Lethargy & Forgetfulness 00:28:15 The Almond Meditation 00:29:30 Drugs That Shift Exteroception Versus Interoception 00:30:36 Emotional Balance, Active & Passive Manipulation 00:32:36 Procrastination: Leveraging Stress, Breathing, Caffeine, L-Tyrosine, Prescription Drugs 00:37:04 When Enough Is Never Enough; How Dopamine Undermines Itself 00:38:58 Dopamine-Prolactin Dynamics: Sex, Reproduction & Refractory Periods 00:40:30 The Coolidge Effect: Novelty-Induced Suppression of Prolactin 00:42:22 Vitamin B6, Zinc As Mild Prolactin Inhibitors 00:43:25 Schizophrenia, Dopamine Hyperactivity and Side Effects of Anti-Dopaminergic Drugs 00:45:08 Prolactin, Post-Satisfaction “Lows” & Extending the Arc of Dopamine 00:48:00 The Chemistry of “I Won, But Now What?” 00:49:00 Healthy Emotional Development: Child and Parent 00:50:03 Never Say “Maybe” (Reward Prediction Error) 00:52:02 Surprise! 00:52:59 Are You Suppressing Your Drive and Motivation By Working Too Late? 00:54:50 Disambiguating Pleasure and Drive: Dopamine Makes Us Anti-Lazy 00:58:00 Beta-Phenylethylamine (PEA), & Acetyl L-Carnitine 01:00:00 Attention Deficit Disorders, Cal Newport Books, Impulsivity & Obesity 01:03:55 Leveraging Dopamine Schedules 01:05:22 Subjective Control of Dopamine and Drug Effects: The “Adderall” Experiment 01:09:03 Caffeine May Protect Dopamine Neurons, Methamphetamine Kills Them 01:10:57 Nicotine: Dopamine, Possible Neuroprotection, Prolactin Increase 01:11:53 Gambling, Intermittent Reinforcement, & Persistent Goal Seeking (Bad and Good) 01:14:14 Intermittent Halting of Celebration; Enjoy Your Wins, But Not All of Them 01:18:38 A Story Example of Intermittent Reward to Maintain Long-Term Drive and Motivation 01:21:25 Corrections & Notes About Spanish Captions & Other Languages Soon 01:24:00 Synthesis & Framework, Zero-Cost Support & A Note About Sponsors  
    Please note that The Huberman Lab Podcast is distinct from Dr. Huberman's tea

    • 1 hr 29 min
    How Foods and Nutrients Control Our Moods | Episode 11

    How Foods and Nutrients Control Our Moods | Episode 11

    This episode explains the brain-body connections that allow the specific foods we eat to control our moods and motivation. I discuss the vagus nerve and its role in dopamine and serotonin release in the brain. I review Omega-3 fatty acids and the key role of the gut microbiome in supporting (or hindering) our mental and emotional states. Many actionable tools are reviewed and discussed related to fasting, ketogenic and plant-based diets, probiotics, fermented foods, fish oils, artificial sweeteners, specific supplements that promote dopamine and serotonin, and some remarkable behavioral (and belief) effects.
    Thank you to our sponsors:
    Theragun - http://theragun.com/huberman InsideTracker - http://insidetracker.com/huberman Athletic Greens - https://athleticgreens.com/huberman  
    Our Patreon page:
    https://www.patreon.com/andrewhuberman  
    Supplements from Thorne:
    http://www.thorne.com/u/huberman  
    Artificial Sweeteners and Gut Microbiome:
    https://pubmed.ncbi.nlm.nih.gov/25231862/ https://pubmed.ncbi.nlm.nih.gov/25231865/ Anti-Depressive Effects of EPAs
    https://pubmed.ncbi.nlm.nih.gov/18247193/ Free Resource: Links to Studies on Supplements Discussed
    https://examine.com/  
    Timestamps below.
    00:00:00 Introduction 00:05:00 Emotions: Aligning Mind & Body 00:06:41 Nutrients, Neurochemicals and Mood 00:08:39 Primitive Expressions and Actions 00:12:30 The Vagus Nerve: Truth, Fiction, Function 00:15:45 “Vagus Stimulation”: A Terrible Concept 00:16:35 Polyvagal Theory 00:18:27 Vagus Senses Many Things, & Moves Our Organs 00:19:35 Sugar Sensing Without Perception of Sweetness 00:23:00 Eating-Induced Anxiety 00:27:30 We Eat Until Our Brain Perceives “Amino Acid Threshold” 00:29:45 Reward Prediction Error: Buildup, Letdown and Wanting More 00:32:01 L-Tyrosine, Dopamine, Motivation, Mood, & Movement 00:34:04 Supplementing L-Tyrosine, Drugs of Abuse, Wellbutrin 00:38:29 Serotonin: Gut, Brain, Satiety and Prozac 00:43:38 Eating to Promote Dopamine (Daytime) & Serotonin (Night Time) 00:44:30 Supplementing Serotonin: Sleep, & Caution About Sleep Disruptions 00:46:40 Examine.com An Amazing Cost-Free Resource with Links to Science Papers 00:48:05 Mucuna Pruriens: The Dopamine Bean with a Serotonin Outer Shell 00:51:00 Emotional Context and Book Recommendation: “How Emotions Are Made” 00:54:55 Exercise: Powerful Mood Enhancer, But Lacks Specificity 00:56:45 Omega-3: Omega-6 Ratios, Fish Oil and Alleviating Depression 01:01:00 Fish Oil as Antidepressant 01:02:40 EPAs May Improve Mood via Heart Rate Variability: Gut-Heart-Brain 01:07:24 Alternatives to Fish Oil to Obtain Sufficient Omega-3/EPAs 01:09:05 L-Carnitine for Mood, Sperm and Ovary Quality, Autism, Fibromyalgia, Migraine 01:16:29 Gut-Microbiome: Myths, Truths & the Tubes Within Us 01:21:55 Probiotics, Brain Fog, Autism, Fermentation 01:25:20 Artificial Sweeteners & the Gut Microbiome: NOT All Bad; It Depends! 01:28:00 Ketogenic, Vegan, & Processed Food Effects, Individual Differences 01:33:20 Fasting-Based Depletion of Our Microbiome 01:35:20 How Mindset Effects Our Responses to Foods: Amazing (Ghrelin) Effects! 01:38:30 How Mindset Controls Our Metabolism 01:41:03 Closing Comments, Thanks, Support & Resources  
    Please note that The Huberman Lab Podcast is distinct from Dr. Huberman's teaching and research roles at Stanford University School of Medicine. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Huberman Lab Podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
    [Title Card Photo Credit: Mike Blabac https://www.blabacphoto.com/]

    • 1 hr 44 min

Customer Reviews

5.0 out of 5
2.1K Ratings

2.1K Ratings

SayleMilne ,

Fully addicted.

As a lover of science and all things about our bodies and brains, thank you. You make very complex information digestible to someone outside the science profession. So many levels, never preachy, always interesting. Many thanks and keep em’ coming!

Keller Dawg ,

Excellent Information

Love everything about this informative podcast!

deposit guy ,

Thank you for your time.

For all of us that don't have time to read and try to understand the studies and reviews about our bodies and health. Andrew takes care of that! This podcast is excellent. And inspires wellness and self-reaserch. Thank you.

Top Podcasts In Health & Fitness