95 episodes

The Huberman Lab Podcast discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For more than 20 years, Dr. Huberman has consistently published original research findings and review articles in top-level peer-reviewed journals, including Nature, Science, Cell, Neuron, and Current Biology. He is a regular member of several National Institutes of Health review panels and a Fellow of the McKnight Foundation and the Pew Charitable Trusts. Dr. Huberman regularly consults for technology development companies, professional athletic organizations, and various units of U.S. and Canadian Special Operations.

Huberman Lab Scicomm Media

    • Health & Fitness
    • 4.9 • 10.2K Ratings

The Huberman Lab Podcast discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For more than 20 years, Dr. Huberman has consistently published original research findings and review articles in top-level peer-reviewed journals, including Nature, Science, Cell, Neuron, and Current Biology. He is a regular member of several National Institutes of Health review panels and a Fellow of the McKnight Foundation and the Pew Charitable Trusts. Dr. Huberman regularly consults for technology development companies, professional athletic organizations, and various units of U.S. and Canadian Special Operations.

    Dr. Casey Halpern: Biology & Treatments for Compulsive Behaviors & Binge Eating

    Dr. Casey Halpern: Biology & Treatments for Compulsive Behaviors & Binge Eating

    My guest is Casey Halpern, M.D., Chief of Stereotactic and Functional Neurosurgery and Professor of Neurosurgery at the Perelman School of Medicine at the University of Pennsylvania. Dr. Halpern’s research and clinical practice focus on using deep brain stimulation to treat compulsive and movement disorders (e.g., binge eating disorders, bulimia, obsessive-compulsive disorder (OCD) and Parkinson’s disease essential tremor, dystonia). We discuss using deep brain stimulation to help patients who suffer from movement and compulsive disorders and applying this treatment to patients afflicted with binge eating. We also explore applications of this technology to other conditions such as OCD, anorexia and tremor, and the future therapeutic directions of the use of non-invasive brain stimulation approaches, including transcranial magnetic stimulation and ultrasound, for the treatment of other psychiatric illnesses and conditions. This episode will interest those curious about the biology of eating, anorexia, bulimia, compulsive thoughts and behaviors, and movement.
    Thank you to our sponsors
    AG1 (Athletic Greens): https://athleticgreens.com/huberman
    ROKA: https://www.roka.com/huberman
    Eight Sleep: https://www.eightsleep.com/huberman
    InsideTracker: https://insidetracker.com/huberman
    Supplements from Momentous
    https://www.livemomentous.com/huberman
    For the full show notes, visit hubermanlab.com
    Timestamps
    (00:00:00) Dr. Casey Halpern & Disordered Eating & Brain Stimulation
    (00:03:18) ROKA, Eight Sleep, InsideTracker
    (00:07:19) Momentous Supplements
    (00:08:28) Neurosurgeon’s View of the Brain, Neurosurgery Specialization
    (00:13:05) Deep Brain Stimulation & Other Unexpected Positive Effects
    (00:17:20) Obsessive Compulsive Disorder (OCD), Prescriptions & Cognitive Therapies
    (00:25:40) Brain Areas in OCD, Risk, Rewards & Addiction
    (00:31:11) AG1 (Athletic Greens)
    (00:32:27) Facial and Vocal Ticks, Stimulants, Stress & Superstition
    (00:39:28) Nucleus Accumbens, Reward Circuits, Eating Disorders & Obesity
    (00:47:18) Stimulation of Nucleus Accumbens, Continuous vs. Episodic Stimulation
    (00:49:49) Binge Eating Disorder & Loss of Control Eating
    (00:53:02) Developing Binge Eating Disorder: Predisposition, Environment, Stress
    (01:02:07) Electrodes in Nucleus Accumbens, Identifying “Craving Cells”
    (01:11:41) Effects of Stimulation, Interrupting Craving, Intermediate Stimulation
    (01:16:46) Anorexia, Obesity & Compulsions, Potential Treatments for Anorexia
    (01:23:14) Non-Invasive Brain Stimulation, Transcranial Magnetic Stimulation
    (01:32:27) MRI-Guided Focused Ultrasound: Tremor, Essential Tremor & Parkinson’s
    (01:36:40) Future of Non-Invasive Brain Stimulation, Epilepsy & Depression
    (01:41:51) Pre-Behavioral States in Compulsion & Awareness, Mood Provocation
    (01:48:02) Machine Learning/Artificial Intelligence & Compulsion Predictions
    (01:53:05) Neurosurgeon Hands, Resistance Training & Deadlifts
    (01:59:00) “Neurosurgeon Calm,” Quality Time & Prioritization, Neurosurgeon Training
    (02:09:53) Daily Habits: Sleep, Exercise, Mediation
    (02:11:59) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn
     Title Card Photo Credit: Mike Blabac
    Disclaimer

    • 2 hr 14 min
    Nicotine’s Effects on the Brain & Body & How to Quit Smoking or Vaping

    Nicotine’s Effects on the Brain & Body & How to Quit Smoking or Vaping

    In this episode, I explain how nicotine impacts the brain and body, including its potent ability to enhance attention, focus, and alertness, increase blood pressure and metabolism and reduce appetite. I discuss nicotine’s ability to increase the action of neurochemicals, including dopamine, norepinephrine, and acetylcholine and activate sympathetic (alertness-promoting) neural circuits. I also discuss common nicotine delivery methods, such as cigarettes, vaping, dip, and snuff, and how they each create their own unique experience and how they, but not nicotine itself, cause cancer and other adverse health effects. I also explain science-based tools to permanently quit smoking cigarettes or vaping, including peer-reviewed clinical hypnosis tools, antidepressants, and alternative nicotine replacement (patches, lozenges, gums etc.). As nicotine is one of the most widely used substances with billions of users — most of whom report wanting to quit — this episode ought to be of interest to former/current nicotine users, those who want to quit smoking or vaping and/or those interested in learning the biology behind how nicotine impacts the brain and body.
    Thank you to our sponsors
    AG1 (Athletic Greens): https://athleticgreens.com/huberman
    Thesis: https://takethesis.com/huberman
    InsideTracker: https://insidetracker.com/huberman
    ROKA: https://www.roka.com/huberman
    Supplements from Momentous
    https://www.livemomentous.com/huberman
    For the full show notes, visit hubermanlab.com
    Timestamps
    (00:00:00) Nicotine
    (00:02:47) Momentous Supplements
    (00:03:41) Tool: Brief Daily Meditation & Focus
    (00:05:59) The Arrow Model of Focus, Alpha GPC & Garlic Supplements
    (00:10:43) Thesis, InsideTracker, ROKA
    (00:14:35) Nicotine Effects vs. Methods of Delivery, Acetylcholine
    (00:19:55) Where is Nicotine Found? Nicotinic Acetylcholine Receptors
    (00:25:12) Nicotine & Effects on the Brain: Appetite, Dopamine & GABA
    (00:30:58) AG1 (Athletic Greens)
    (00:32:11) Nicotine, Acetylcholine & Attentional “Spotlighting”
    (00:37:29) Nicotine, Norepinephrine & Alertness/Energy
    (00:41:10) Nicotine & Effects on Appetite & Metabolism
    (00:46:47) Nicotine & Effects on Body: Sympathetic Tone
    (00:51:29) Nicotine & Cognitive Work vs. Physical Performance
    (00:55:08) Nicotine Delivery Methods & Side Effects, Young People & Dependency
    (00:58:35) Smoking, Vaping, Dipping & Snuffing: Carcinogens & Endothelial Cells
    (01:02:34) Smoking, Vaping, Dipping & Snuffing: Negative Impacts on Lifespan & Health
    (01:09:23) How to Quit Smoking, Nicotine Cravings & Withdrawal
    (01:13:56) Vaping & Nicotine, Rates of Effect Onset, Dopamine, Addiction & Depression
    (01:25:06) Tool: Quitting Smoking & Clinical Hypnosis, Reveri
    (01:30:16) Bupropion (Wellbutrin) & Quitting Smoking
    (01:36:24) Tool: A Nicotine Replacement Schedule to Quit Smoking, Nicotine Patch/Gum
    (01:41:52) Tool: Biological Homeostasis & Nicotine Withdrawal, The “First Week” Strategy
    (01:51:39) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook
    Title Card Photo Credit: Mike Blabac
    Disclaimer

    • 1 hr 53 min
    Dr. David Anderson: The Biology of Aggression, Mating, & Arousal

    Dr. David Anderson: The Biology of Aggression, Mating, & Arousal

    My guest is David Anderson, PhD, a world expert in the science of sexual behavior, violent aggression, fear and other motivated states. Dr. Anderson is a Professor of Biology at the California Institute of Technology (Caltech), a member of the National Academy of Sciences and an investigator with the Howard Hughes Medical Institute (HHMI). We discuss how states of mind (and body) arise and persist and how they probably better explain human behavior than emotions per se. We also discuss the many kinds of arousal that create varying levels of pressure for certain behaviors to emerge. We discuss different types of violent aggression and how they are impacted by biological sex, gender, context, prior experience, and hormones, and the neural interconnectedness of fear, aggression and sexual behavior. We also discuss peptides and their role in social isolation-induced anxiety and aggression. Dr. Anderson also describes novel, potentially powerful therapeutics for mental health. This episode should interest anyone wanting to learn more about mental health, human emotions, sexual and/or violent behavior.  
    Thank you to our sponsors
    AG1 (Athletic Greens): https://athleticgreens.com/huberman
    Levels: https://levels.link/huberman
    Helix Sleep: https://helixsleep.com/huberman
    LMNT: https://drinklmnt.com/huberman
    Supplements from Momentous
    https://www.livemomentous.com/huberman
    For the full show notes, visit hubermanlab.com
    Timestamps
    (00:00:00) Dr. David Anderson, Emotions & Aggression 
    (00:03:33) Momentous Supplements 
    (00:04:27) Levels, Helix Sleep, LMNT 
    (00:08:10) Emotions vs. States
    (00:10:36) Dimensions of States: Persistence, Intensity & Generalization
    (00:14:38) Arousal & Valence 
    (00:18:11) Aggression, Optogenetics & Stimulating Aggression in Mice, VMH
    (00:24:42) Aggression Types: Offensive, Defensive & Predatory 
    (00:29:20) Evolution & Development of Defensive vs. Offensive Behaviors, Fear
    (00:35:38) Hydraulic Pressures for States & Homeostasis
    (00:38:33) AG1 (Athletic Greens)
    (00:39:46) Hydraulic Pressure & Aggression
    (00:44:50) Balancing Fear & Aggression
    (00:48:31) Aggression & Hormones: Estrogen, Progesterone & Testosterone
    (00:52:33) Female Aggression, Motherhood
    (00:59:48) Mating & Aggressive Behaviors 
    (01:05:10) Neurobiology of Sexual Fetishes 
    (01:10:06) Temperature, Mating Behavior & Aggression
    (01:15:25) Mounting: Sexual Behavior or Dominance?
    (01:20:59) Females & Male-Type Mounting Behavior
    (01:24:40) PAG (Periaqueductal Gray) Brain Region: Pain Modulation & Fear 
    (01:30:38) Tachykinins & Social Isolation: Anxiety, Fear & Aggression 
    (01:43:49) Brain, Body & Emotions; Somatic Marker Hypothesis & Vagus Nerve 
    (01:52:52) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, AG1 (Athletic Greens), Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips
    Title Card Photo Credit: Mike Blabac
    Disclaimer

    • 1 hr 55 min
    Focus Toolkit: Tools to Improve Your Focus & Concentration

    Focus Toolkit: Tools to Improve Your Focus & Concentration

    In this episode, I provide a list of behavioral, nutritional, and supplement-based tools you can use to improve your ability to get into a focused state to do mental or physical work. I explain science-supported strategies for transitioning into focus, maintaining focus during the work bout, and exiting the focus session, which is also critical, including decompression/defocusing tools. I explain when and how to use: binaural beats, caffeine, deliberate cold exposure, the pros and cons of working in fasted vs. fed states, and supplements and foods that enhance dopamine, epinephrine (i.e., adrenaline) and acetylcholine to promote optimal focus. Also, I explain how short behavioral practices, such as meditation and visual gaze training, will benefit your ability to focus over the long term. As deep focus is crucial to significantly improve cognitive or physical performance in any realm, this episode should be useful to anyone. By the end, you’ll have an essential toolkit of science-supported, low- to zero-cost focus and concentration strategies to select from that can be tailored to your physical and mental performance needs.
    Thank you to our sponsors
    AG1 (Athletic Greens): https://athleticgreens.com/huberman
    Thesis: https://takethesis.com/huberman
    LMNT: https://drinklmnt.com/huberman
    Eight Sleep: https://www.eightsleep.com/huberman
    Virtusan: https://virtusan.com/huberman
    Supplements from Momentous
    https://www.livemomentous.com/huberman
    For the full show notes, visit hubermanlab.com
    Timestamps
    (00:00:00) Focus Toolkit 
    (00:04:25) Momentous Supplements 
    (00:05:38) Thesis, LMNT, Eight Sleep 
    (00:09:37) The “Arrow Model” of Focus: Epinephrine, Acetylcholine & Dopamine
    (00:15:15) Modulation vs. Mediation, Importance of Sleep
    (00:18:11) Tool: Binaural Beats to Improve Concentration 
    (00:20:54) Tool: White, Brown & Pink Noise, Transition to Focused State
    (00:22:55) Warm-Up for Cognitive Work, Refocusing Attention & Neuroplasticity 
    (00:26:14) Tool: Ultradian Cycles: Warm-Up, Maintaining Focus & Deliberate Defocusing 
    (00:31:22) How Many Daily Ultradian Cycles Can One Perform? 
    (00:34:14) AG1 (Athletic Greens)
    (00:35:35) Virtusan: Mental & Physical Health Journeys 
    (00:36:52) Tool: Fasted vs. Fed States & Focus, Prevent an Afternoon Crash, Ketosis
    (00:45:52) Tool: Foods to Improve Focus & Regulating Food Volume
    (00:47:53) Tool: Caffeine & Focused Work, Dopamine Efficacy, Alertness
    (00:52:55) Tool: Stress & Improved Concentration 
    (00:55:46) Tool: Deliberate Cold Exposure & Focus, Dopamine & Epinephrine 
    (01:00:39) Layer Focusing Tools & Design Your Own Protocols 
    (01:01:19) Tool: Short Meditation & Improved Ability to Refocus 
    (01:07:40) Tool: Yoga Nidra, Non-Sleep Deep Rest (NSDR) & Defocus Periods
    (01:12:13) Tool: Hypnosis & Focus/Deep Relaxation States
    (01:16:07) Optimal Time of Day to Use Specific Tools
    (01:16:46) Tool: Overt Visual Focus & Deliberate Gaze 
    (01:20:42) Covert Visual Focus; Deliberate Gaze Warm-Up & Focused Work 
    (01:24:43) Tool: Omega-3 Essential Fatty Acids 
    (01:27:28) Tool: Creatine Monohydrate 
    (01:29:10) Tool: Alpha-GPC & Acetylcholine, Increased Risk of Stroke? & Garlic 
    (01:33:52) Tool: L-Tyrosine Supplements & Food
    (01:34:47) Combining & Choosing Focus Tools, Variability 
    (01:36:50) ADHD Prescriptions, Training Neural Circuits, Maintenance & Reduced Dosage
    (01:39:19) Tool: Optimal Order Approaching Focus Tools, Prescriptions & Dependency 
    (01:42:56) Tool: Phenylethylamine & Dopamine
    (01:44:50) Tool: Other Supplements to Enhance Dopamine, Epinephrine & Acetylcholine 
    (01:46:46) Behavioral, Nutrition & Supplement Tools for Focus
    (01:49:12) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Momentous Supplements, AG1 (Athletic Greens), Instagram, Twitter, Neural Network Newsletter
    Title Card Photo Credit: Mike Blabac
    Disclaimer

    • 1 hr 51 min
    LIVE EVENT Q&A: Dr. Andrew Huberman Question & Answer in Portland, OR

    LIVE EVENT Q&A: Dr. Andrew Huberman Question & Answer in Portland, OR

    Recently I had the pleasure of hosting two live events, one in Seattle, WA and one in Portland, OR. These events were part of a lecture series called The Brain Body Contract. My favorite part of each evening was the question & answer period, where I had the opportunity to answer questions from the attendees of each event. Included here is the Q&A from our event in Portland, OR.
    Attend The Brain Body Contract Live Events
    Los Angeles, CA: October 16, 2022
    New York, NY: November 9, 2022
    https://hubermanlab.com/tour
    Thank you to our sponsors
    Momentous: https://www.livemomentous.com/huberman
    InsideTracker: https://insidetracker.com/huberman
    Timestamps
    (00:00:00) The Brain Body Contract Q&A
    (00:01:08) Momentous Supplements, InsideTracker
    (00:01:36) Upcoming Live Events: Los Angeles & New York
    (00:02:16) What Are the Current Best Practices for Post-TBIs? Thoughts on Hyperbaric Oxygen Therapy?
    (00:08:03) Are There Effective Ways to Decrease Dopamine When You Get Too Much of It?
    (00:13:50) How and When to Improve Brain Plasticity if You Have 10 Minutes a Day?
    (00:17:51) How to Use Supplements to Optimize Health When Career Prevents Consistent Routines?
    (00:21:09) How Is Social Media Changing Our Brains?
    (00:25:10) What New Piece of Neurological Research Most Excites You?
    (00:28:35) Do You Believe in the Wim How Method? Does It Work? What's Happening in the Brain?
    (00:37:08) Can Red Light Therapy Help Treat Exercise Intolerance and Fatigue in Mitochondrial Disease?
    (00:40:39) Is It Possible to Over Do Ice Baths?
    (00:46:10) What Are Your Favorite Brain Hacks for Doing Hard Things?
    (00:48:25) What Do You Fear? How Do You Manage Fear?
    (00:50:05) Conclusion
    Title Card Photo Credit: Mike Blabac
    Disclaimer

    • 51 min
    Dr. Erich Jarvis: The Neuroscience of Speech, Language & Music

    Dr. Erich Jarvis: The Neuroscience of Speech, Language & Music

    My guest this episode is Dr. Erich Jarvis, PhD—Professor and the Head of the Laboratory of Neurogenetics of Language at Rockefeller University and Investigator with the Howard Hughes Medical Institute (HHMI). Dr. Jarvis’ research spans the molecular and genetic mechanisms of vocal communication, comparative genomics of speech and language across species and the relationship between speech, language and movement. We discuss the unique ability of humans (and certain animal species) to learn and communicate using complex language, including verbal speech production and the ability to interpret both written and spoken language. We also discuss the connections between language, singing and dance and why song may have evolved before language. Dr. Jarvis also explains some of the underlying biological and genetic components of stutter/speech disorders, non-verbal communication, why it's easiest to learn a language as a child and how individuals can learn multiple languages at any age. This episode ought to be of interest to everyone interested in the origins of human speech, language, music and culture and how newer technology, such as social media and texting, change our brains. 
    Thank you to our sponsors
    AG1 (Athletic Greens): https://athleticgreens.com/huberman
    InsideTracker: https://insidetracker.com/huberman
    ROKA: https://roka.com/huberman
    LMNT: https://drinklmnt.com/huberman
    Supplements from Momentous
    https://www.livemomentous.com/huberman
    For the full show notes, visit hubermanlab.com
    Timestamps
    (00:00:00) Dr. Erich Jarvis & Vocal Communication
    (00:03:43) Momentous Supplements 
    (00:04:36) InsideTracker, ROKA, LMNT 
    (00:08:01) Speech vs. Language, Is There a Difference?  
    (00:10:55) Animal Communication, Hand Gestures & Language 
    (00:15:25) Vocalization & Innate Language, Evolution of Modern Language    
    (00:21:10) Humans & Songbirds, Critical Periods, Genetics, Speech Disorders 
    (00:27:11) Innate Predisposition to Learn Language, Cultural Hybridization
    (00:31:34) Genes for Speech & Language
    (00:35:49) Learning New or Multiple Languages, Critical Periods, Phonemes 
    (00:41:39) AG1 (Athletic Greens) 
    (00:42:52) Semantic vs. Effective Communication, Emotion, Singing
    (00:47:32) Singing, Link Between Dancing & Vocal Learning 
    (00:52:55) Motor Theory of Vocal Learning, Dance 
    (00:55:03) Music & Dance, Emotional Bonding, Genetic Predispositions
    (01:04:11) Facial Expressions & Language, Innate Expressions
    (01:09:35) Reading & Writing 
    (01:15:13) Writing by Hand vs. Typing, Thoughts & Writing
    (01:20:58) Stutter, Neurogenetics, Overcome Stutter, Conversations
    (01:26:58) Modern Language Evolution: Texting, Social Media & the Future
    (01:36:26) Movement: The Link to Cognitive Growth 
    (01:40:21) Comparative Genomics, Earth Biogenome Project, Genome Ark, Conservation
    (01:48:24) Evolution of Skin & Fur Color
    (01:51:22) Dr. Erich Jarvis, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Momentous Supplements, AG1 (Athletic Greens), Instagram, Twitter Neural Network Newsletter, Huberman Lab Clips
    Title Card Photo Credit: Mike Blabac
    Disclaimer

    • 1 hr 54 min

Customer Reviews

4.9 out of 5
10.2K Ratings

10.2K Ratings

_chelz_belz ,

Informative and applicable

So glad I found this podcast! The discussions are fascinating and I found the sleep podcast to be particularly helpful. Thank you for being here and distributing this information!

Andrew4891 ,

High level info

This podcast is high level information laid out is a logic manner. Andrew makes complicated processes/terms easy to follow for the lay person.

M-Kincaid ,

Thank you!

Thank you for providing science based research in layman terms!

You Might Also Like

Scicomm Media
Peter Attia, MD
Dr. Matt Walker
Ben Greenfield
Lewis Howes
InsideTracker