12 episodes

On this podcast, Christina Applegate and Jamie-Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

MeSsy with Christina Applegate & Jamie-Lynn Sigler Wishbone Production

    • Society & Culture
    • 4.9 • 2.5K Ratings

On this podcast, Christina Applegate and Jamie-Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

    Katie Couric

    Katie Couric

    This week, Christina and Jamie are joined by Katie Couric. They discuss the importance of community and honesty, why we need more collaboration over competition, the changing media landscape, and more. 
    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This show is sponsored by:
    Maybelline - If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    Lolavie -Get 15% off LolaVie with the code MESSY at https://www.lolavie.com/MESSY #lolaviepod 
    Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout visit cionic.com

    • 1 hr 12 min
    Jean Smart

    Jean Smart

    This week, Christina and Jamie are joined by Jean Smart. They share memories from when Christina and Jean worked together, and discuss taking back your power, embracing the quiet moments, her career trajectory, and much more.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This show is sponsored by:
    Maybelline- If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    Vuori -Get 20% off your FIRST purchase of the most comfortable and versatile clothing on the planet at vuori.com/MESSY
    Zoc Doc - Go to Zocdoc.com/MESSY and download the Zocdoc app for FREE. Then find and book a top-rated doctor today. 

    • 57 min
    Body Talk

    Body Talk

    This week, Christina and Jamie open up about their battles with eating disorders and self-esteem. They reflect on the moments that changed their lives, and discuss body dysmorphia, societal conditioning, how they each got to a healthier place, and more.
    *Trigger warning: discussion covers eating disorders and body image*

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    Maybelline: If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    BetterHelp: This episode is sponsored by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.”
    Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout visit cionic.com

    • 55 min
    How Did You Know?

    How Did You Know?

    This week, Christina and Jamie discuss giving up control, feeling judgement, and Jamie shares how she knew to get tested for MS. They also answer some listener questions.
    Parts of this episode were recorded in 2023.
    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    Maybelline: If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    Lume: Control Body Odor ANYWHERE with @lumedeodorant and get 15% off with promo code messy at LumeDeodorant.com! #lumepod
    Vuori: For our listeners, they are offering 20% off your FIRST purchase. Get yourself some of the most comfortable and versatile clothing on the planet at vuori.com/MESSY
    BetterHelp: This episode is sponsored by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.

    • 1 hr 5 min
    Jimmy Kimmel

    Jimmy Kimmel

    This week, Christina and Jamie are joined by their friend, Jimmy Kimmel. They discuss finding humor in tough situations, the things he still wants to accomplish, speaking from your heart, mean tweets, and much more.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This show is sponsored by:
    Maybelline - If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    Lolavie - Get 15% off LolaVie with code MESSY at https://www.lolavie.com/MESSY! #lolaviepod
    ZocDoc - Go to Zocdoc.com/MESSY and download the Zocdoc app for FREE. Then find and book a top-rated doctor today

    • 53 min
    Can I Be Honest?

    Can I Be Honest?

    This week, Christina and Jamie discuss feeling obligated to be strong, the importance of being there for each other, wearing diapers, and much more. They also answer some listener questions.
    Parts of this episode were recorded in 2023.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    Maybelline - If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more.
    Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout visit cionic.com

    Jamie-Lynn Sigler is a paid spokesperson for Novartis. This podcast is independent from Jamie-Lynn Sigler’s collaboration with Novartis.

    • 48 min

Customer Reviews

4.9 out of 5
2.5K Ratings

2.5K Ratings

Sasha boo 1711 ,

Best interview

Katie Couric omg I loved every minute of it!!!! Jamie made me cry today too she is the sweetest and Christina as always makes me cry.. but laugh more and for that I am grateful!!

Haarene ,

Guests

Started watching this show out of curiosity since I've had myasthenia gravis since 2016. Show's good. Wish guests were real people with autoimmune conditions sharing achievements, struggles, and treatments.

Strong Sissy ,

Being heard!

Thank you, thank you both! Your honesty and truth about how you deal with MS and life is so real. I can relate to you both. Diagnosed with RR MS in 2000 and my identical twin sister was diagnosed 10 years earlier. Unfortunately, she is in a different place with her MS, but I try to live for the both of us. Some days are hard, but every Tuesday listening to your Podcast makes the day a-little easier and funnier! ❤️

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