Diabetes Care "On Air‪"‬ American Diabetes Association

Welcome to episode no. 18 (April 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the April 2024 issue of Diabetes Care. 
Notably, this episode is a more expansive journey than usual. Dive in at your own pace—segment by segment— or all at once. You can find time stamps for each segment in the notes below. 
Mike and Alice begin the show by announcing that the April episode will be unlike any episode of Diabetes Care “On Air” that they’ve done. This month, they focus on a Special Collection of articles in the April issue of Diabetes Care. This collection features 10 articles from the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) as well as a commentary on these articles. The full collection is openly accessible at https://diabetesjournals.org/collection/2066/Reports-from-the-GRADE-Study.  
2:06: Mike and Alice begin the deep dive into the GRADE articles by bringing in David M. Nathan, chair of the steering committee for the GRADE study. They are then joined by Jennifer B. Green, a member of the GRADE Research Group and an associate editor of Diabetes Care. 
9:56: After David M. Nathan and Jennifer B. Green give an overview and synopsis of the collection of GRADE articles, Alice brings in Matthew C. Riddle, former editor in chief of Diabetes Care and author of a commentary on the GRADE articles, to get his general impression of and insights into the GRADE collection. Dr. Riddle’s commentary on the GRADE collection is openly available at https://doi.org/10.2337/dci24-0008. 
As the discussion continues, the speakers touch on each of the 10 articles of the Special Collection in the April issue of Diabetes Care. The following is a list of all the articles in the collection as well as the commentary, along with links to where these articles can be found (all are openly available). 
Riddle. Individualizing treatment of type 2 diabetes after metformin: more insights from GRADE. https://doi.org/10.2337/dci24-0008  Gonzalez et al. Differential effects of type 2 diabetes treatment regimens on diabetes distress and depressive symptoms in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). https://doi.org/10.2337/dc23-2459  Garvey et al. Association of baseline factors with glycemic outcomes in GRADE: a comparative effectiveness randomized clinical trial. https://doi.org/10.2337/dc23-1782  Banerji et al. Mortality in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). https://doi.org/10.2337/dc23-1356  Cherrington et al. Does emotional distress predict worse glycemic control over time? Results from the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). https://doi.org/10.2337/dc23-0642 Hoogendoorn et al. Emotional distress predicts reduced type 2 diabetes treatment adherence in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). https://doi.org/10.2337/dc23-1401 Rasouli et al. Longitudinal effects of glucose-lowering medications on β-cell responses and insulin sensitivity in type 2 diabetes: the GRADE randomized clinical trial. https://doi.org/10.2337/dc23-1070 Kirkman et al. Comparative effects of randomized second-line therapy for type 2 diabetes on a composite outcome incorporating glycemic control, body weight, and hypoglycemia: an analysis of the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). https://doi.org/10.2337/dc23-1332 Utzschneider et al. Impact of insulin sensitivity and β-cell function over time on glycemic outcomes in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE): differential treatment effects of dual therapy. https://doi

Welcome to episode no. 17 (March 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the March 2024 issue of Diabetes Care. 
Mike and Alice begin the show by reminding listeners of ADA’s special offer to new members. Individuals who would like to take advantage of this time-limited discount can sign up for an ADA professional membership at professional.diabetes.org/membership. Use discount code “NEW24” for 25% off ADA membership. This offer will expire 31 March 2024.  
1:28: Mike interviews Daniel R. Tilden, first author of “Disparities in Continuous Glucose Monitor Use Between Children With Type 1 Diabetes Living in Urban and Rural Areas.” This study is an editor-selected feature article appearing in the March 2024 issue and is openly accessible at https://doi.org/10.2337/dc23-1564. 
16:55: Alice interviews Joseph Henson, Andrew P. Hall, and Melanie J. Davies, authors of “Waking Up to the Importance of Sleep in Type 2 Diabetes Management: A Narrative Review.” This study is an editor-selected feature article appearing in the March 2024 issue and is openly accessible at https://doi.org/10.2337/dci23-0037.  
31:05: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the March 2024 issue of Diabetes Care. Studies highlighted in this segment include: 
Cheng et al. Managing Impending Nonsevere Hypoglycemia With Oral Carbohydrates in Type 1 Diabetes: The REVERSIBLE Trial. https://doi.org/10.2337/dc23-1328   Christensen et al. Kidney Disease in Women With Previous Gestational Diabetes Mellitus: A Nationwide Register-Based Cohort Study. https://doi.org/10.2337/dc23-1092    Virostko et al. Longitudinal Assessment of Pancreas Volume by MRI Predicts Progression to Stage 3 Type 1 Diabetes. https://doi.org/10.2337/dc23-1681 Fu et al. Risk Assessment for Gastrointestinal Diseases via Clinical Dimension and Genome-Wide Polygenic Risk Scores of Type 2 Diabetes: A Population-Based Cohort Study. https://doi.org/10.2337/dc23-0978    Roubille et al. Low-Dose Colchicine in Patients With Type 2 Diabetes and Recent Myocardial Infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT). https://doi.org/10.2337/dc23-1825   Chaudhary et al. Low Awareness of Diabetes as a Major Risk Factor for Cardiovascular Disease in Middle- and High-Income Countries. https://doi.org/10.2337/dc23-1731   Don’t forget our special offer for new ADA members! Go to professional.diabetes.org/membership and use discount code “NEW24” for 25% off ADA membership. Offer expires 31 March 2024. 
To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.

Welcome to episode no. 16 (February 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the February 2024 issue of Diabetes Care. 
Alice begins the show by reminding listeners of ADA’s special offer to new members. Individuals who would like to take advantage of this time-limited discount can sign up for an ADA professional membership at professional.diabetes.org/membership. Use discount code “NEW24” for 25% off ADA membership. This offer will expire 31 March 2024.  
2:10: Alice interviews Laura Jacobsen, who took the photograph featured on the cover of the February issue of Diabetes Care. Each month, the editors of Diabetes Care select cover art from reader submissions. If you are interested in submitting cover art, please visit https://diabetesjournals.org/care/pages/submit_a_cover_image. Read more about Dr. Jacobsen and her photo in “About the Artist: Laura Jacobsen, MD”  (https://diabetesjournals.org/care/article/47/2/181/154139/About-the-Artist-Laura-Jacobsen-MD). 
8:50: Mike interviews Borja del Pozo Cruz, one of the senior authors of “Optimal Dose and Type of Physical Activity to Improve Glycemic Control in People Diagnosed With Type 2 Diabetes: A Systematic Review and Meta-analysis.” https://doi.org/10.2337/dc23-0800
25:30: Alice interviews Baojun Wu and L. Keoki Williams, first author and senior author, respectively, of “Genome-Wide Association Study Identifies Pharmacogenomic Variants Associated With Metformin Glycemic Response in African American Patients With Type 2 Diabetes.” https://doi.org/10.2337/dc22-2494
In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the February 2024 issue of Diabetes Care. Studies highlighted in this segment include: 
Karagiannis et al. A Methodological Framework for Meta-analysis and Clinical Interpretation of Subgroup Data: The Case of Major Adverse Cardiovascular Events With GLP-1 Receptor Agonists and SGLT2 Inhibitors in Type 2 Diabetes. https://doi.org/10.2337/dc23-0925 Wang et al. Vaspin: A Novel Biomarker Linking Gluteofemoral Body Fat and Type 2 Diabetes Risk. https://doi.org/10.2337/dc23-1488  Beato-Bibora et al. A Multicenter Prospective Evaluation of the Benefits of Two Advanced Hybrid Closed-Loop Systems in Glucose Control and Patient-Reported Outcomes in a Real-world Setting. https://doi.org/10.2337/dc23-1355 Visaria et al. Ambient Heat and Risk of Serious Hypoglycemia in Older Adults With Diabetes Using Insulin in the U.S. and Taiwan: A Cross-National Case-Crossover Study. https://doi.org/10.2337/dc23-1189  Foster et al. Low-Dose Antithymocyte Globulin: A Pragmatic Approach to Treating Stage 2 Type 1 Diabetes. https://doi.org/10.2337/dc23-1750 Kaminski et al. Assessment of Glycemic Control by Continuous Glucose Monitoring, Hemoglobin A1c, Fructosamine, and Glycated Albumin in Patients With End-Stage Kidney Disease and Burnt-Out Diabetes. https://doi.org/10.2337/dc23-1276 Don’t forget our special offer for new ADA members! Go to professional.diabetes.org/membership and use discount code “NEW24” for 25% off ADA membership. Offer expires 31 March 2024. 
To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.

Welcome to episode no. 15 (January 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the January 2024 issue of Diabetes Care. 
After wishing all the listeners a happy and healthy New Year, Alice and Mike announce ADA’s special offer to new members. Individuals who would like to take advantage of this time-limited discount can sign up for an ADA professional membership at professional.diabetes.org/membership. Use discount code “NEW24” for 25% off ADA membership. This offer will expire 31 March 2024.  
3:28: Mike interviews Frans Pouwer and Loretta Vileikyte, first and senior authors, respectively, of a Perspectives on Care titled “Psychosocial Care for People with Diabetic Neuropathy: Time for Action” (https://doi.org/10.2337/dci23-0033). 
25:19: Alice interviews Alka Kanaya about her 2023 Kelly West Award lecture, “Diabetes in South Asians: Uncovering Novel Risk Factors With Longitudinal Epidemiologic Data: Kelly West Award Lecture 2023” https://doi.org/10.2337/dci23-0068.
44:15:  In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the January 2024 issue of Diabetes Care. Studies highlighted in this segment include:
Sanusi et al. Association of Continuous Glucose Monitoring Metrics With Pregnancy Outcomes in Patients With Preexisting Diabetes. https://doi.org/10.2337/dc23-0636 Sherwood et al. Randomized Trial of the Insulin-Only iLet Bionic Pancreas for the Treatment of Cystic Fibrosis– Related Diabetes. https://doi.org/10.2337/dc23-1411  Baekdal et al. Empagliflozin Normalizes Fasting Hyperglycemia and Improves Postprandial Glucose Tolerance in Totally Pancreatectomized Patients: A Randomized, Double-Blind, Placebo-Controlled Crossover Study. https://doi.org/10.2337/dc23-0645 Parviainen et al. Incidence of Type 1 Diabetes in Relation to Exposure to Rotavirus Infections in Pre- and Postvaccine Birth Cohorts in Finland. https://doi.org/10.2337/dc23-1203  Umapathysivam et al. Euglycemic Ketoacidosis in Two Patients Without Diabetes After Introduction of Sodium–Glucose Cotransporter 2 Inhibitor for Heart Failure With Reduced Ejection Fraction. https://doi.org/10.2337/dc23-1163 Narcisse et al. Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease and Diabetes Mellitus: A Subgroup Analysis of the ADAPTABLE Trial. https://doi.org/10.2337/dc23-0749 Don’t forget our special offer for new ADA members! Go to professional.diabetes.org/membership and use discount code “NEW24” for 25% off ADA membership. Offer expires 31 March 2024. 
To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.

Welcome to episode no. 14, a very special episode of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, along with special guests Dr. Stephanie Fitzpatrick and Dr. Seth Berkowitz, for an examination of the 2023 Diabetes Care Symposium, the 2023 Clinical Care Commission Report to Congress, and the life and achievements of Dr. Felicia Hill-Briggs.  
0:38: Mike introduces the guests for this special episode, Drs. Stephanie Fitzpatrick and Dr. Seth Berkowitz. Alice announces that she and Mike are dedicating this special episode to the memory of Dr. Felicia Hill-Briggs, who passed away on 23 June 2023. Dr. Fitzpatrick, who did her postdoctoral fellowship with Dr. Hill-Briggs, remembers Dr. Hill-Briggs for her professional achievements and her collaborative and thoughtful approach to research.  
3:00: Mike talks with Dr. Fitzpatrick about the symposium article that she coauthored with Dr. Hill-Briggs, “Overview of Social Determinants of Health in the Development of Diabetes.” This study is from the Diabetes Care Symposium that appears in the September 2023 issue, and it is openly accessible at https://doi.org/10.2337/dci23-0001. The entire collection of Diabetes Care Symposium articles is openly accessible at https://diabetesjournals.org/collection/1803/Diabetes-Care-Symposium-2023.
6:00: Alice interviews Dr. Berkowitz, lead author of the Diabetes Care Symposium article “Three Lessons About Diabetes and the Social Determinants of Health,” which was also presented at the Diabetes Care Symposium and appeared in the September 2023 issue of Diabetes Care. It is openly accessible at https://doi.org/10.2337/dci23-0045. Alice and Dr. Berkowitz also discuss the article by Levi et al. that was presented at the symposium, “Food Insecurity and Diabetes: Overview of Intersections and Potential Dual Solutions.” This article is also openly accessible at https://doi.org/10.2337/dci23-0002.
13:20: Mike and Dr. Fitzpatrick discuss the final article in the Diabetes Care Symposium on SDOH, “The Impact of Neighborhoods on Diabetes Risk and Outcomes: Centering Health Equity,” by Mujahid et al. This article is openly accessible at https://doi.org/10.2337/dci23-0003.
18:20: Alice brings up the Clinical Care Commission Report to Congress, which appeared as a special article collection in the February 2023 issue of Diabetes Care.  She and Dr. Berkowitz discuss the importance of this collection, which focused in part on SDOH and the development of diabetes. The collection of articles from the Clinical Care Commission Report to Congress is available at https://diabetesjournals.org/collection/1586/The-Clinical-Care-Commission-Report-to-Congress.  
To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.

Welcome to episode no. 13 (December 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the December 2023 issue of Diabetes Care.  
1:45: Alice interviews Kamlesh Khunti, lead author of “Diabetes and Multiple Long-term Conditions: A Review of Our Current Global Health Challenge.” This study is an editor-selected feature article appearing in the December 2023 issue and is openly accessible at https://doi.org/10.2337/dci23-0035.
18:10: Mike interviews Casper K. Nielsen, lead author of “Dasiglucagon Treatment for Postprandial Hypoglycemia After Gastric Bypass: A Randomized, Double-Blind, Placebo-Controlled Trial.” This study is also an editor-selected feature article appearing in the December 2023 issue and is openly accessible at https://doi.org/10.2337/dc23-1193.
34:00: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the December 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Xiao et al. Alignment Between 24-h Light-Dark and Activity-Rest Rhythms Is Associated With Diabetes and Glucose Metabolism in a Nationally Representative Sample of American Adults. https://doi.org/10.2337/dc23-1034     Zou et al. Rare Variant in Metallothionein 1E Increases the Risk of Type 2 Diabetes in a Chinese Population. https://doi.org/10.2337/dc22-2031   Zaharia et al. Reduced Insulin Clearance Differently Relates to Increased Liver Lipid Content and Worse Glycemic Control in Recent-Onset Type 2 and Type 1 Diabetes. https://doi.org/10.2337/dc23-1267 Hsieh et al. COVID-19 Vaccination Prior to SARS-CoV-2 Infection Reduced Risk of Subsequent Diabetes Mellitus: A Real-World Investigation Using U.S. Electronic Health Records. https://doi.org/10.2337/dc23-0936 Renard et al. Safety and Efficacy of Sustained Automated Insulin Delivery Compared With Sensor and Pump Therapy in Adults With Type 1 Diabetes at High Risk for Hypoglycemia: A Randomized Controlled Trial. https://doi.org/10.2337/dc23-0685 Donovan et al. A Randomized Trial of Closed-Loop Insulin Delivery Postpartum in Type 1 Diabetes. https://doi.org/10.2337/dc23-0882   To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.