Faces of Digital Health Tjasa Zajc

AI and predictive modeling to understand an individual’s immune system function and predict treatment response are still in very early stages. We dream about precision medicine and getting every answer we can for ourselves when we get sick. However, if we look at genomics, only about 20 percent of human coding genes are well-studied. The remaining 80 percent (about 16,000 genes, along with the proteins they make) are largely a mystery. 
In this episode, you will hear more about the field of immuno-oncology, understand the correlation between tumor development and immune system response, and trends in cancer detection and prevention, especially liquid biopsies - tests for detecting tumors in blood samples. 
Speaker: Brian Hashemi - Executive Chairman and CEO of Novigenix - a Swiss-based biotech company using AI and RNA sequence analysis to capture the cancer immunity cycle during the multi-stage disease progression and response to therapy.
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https://fodh.substack.com/

Show notes:
[00:02:00] The use of AI and RNA sequence analysis in capturing the cancer immunity cycle and disease progression
[00:04:00] Biotech in Switzerland
[00:06:00] The impact of Swiss biotech capabilities on global healthcare and the specific advancements made by Swiss companies in the field.
[00:08:00] Predictions and hopes for the future of healthcare technology, especially in the realms of cancer detection and treatment.
[00:10:00] Challenges and opportunities in biotech, and the role of AI in advancing healthcare.
[00:12:00] Challenges in Colorectal Cancer Screening
[00:14:00] The Impact of Liquid Biopsy on Clinical Trials and Drug Development
[00:16:00] Market Adoption and Patient Accessibility to Liquid Biopsy Tests
[00:18:00] The Future of Liquid Biopsy and Precision Medicine
[00:20:00] Real-world Application and Impact of Novel Biomarkers
[00:22:00] Expanding the Reach of Novel Diagnostics Beyond Switzerland
[00:24:00] Partnerships and Collaborations to Accelerate Adoption

The Gulf Cooperation Council (GCC) brings together six Arab countries – Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates 
When one reads about the GCC countries, there’s nothing but the impression of prosperity: high investments, determination, and enthusiasm in tech-supported healthcare. 
The spending on healthcare by the GCC governments is on an astronomical rise. From a regionwide US$2.4 billion in 2016, it rose to more than US$30 billion in 2021 and is projected to surpass US$104 billion this year, according to a report from the UAE Ministry of Economy. 
In this episode, Pilar Fernandez Hermida International Go-to-Market expert with 20+ years of experience launching sales & partner ecosystem strategies, talks about the potential of the Middle East and MENA region for healthtech companies, the culture in the Middle East, how to interpret different style of communication here, what are the common entrepreneurial misconceptions, and where to find opportunities. Pilar says that the entrepreneurial spirit here is 10-times as strong as in the US, and that biotech and drug development are the next thing to watch for in the region.


www.facesofdigitalhealth.com
Newsletter: https://fodh.substack.com/
Show notes:

[00:02:00] Pilar Fernandez Hermida, an expert in healthcare market strategies, shares insights from Abu Dhabi.

[00:04:00] Analysis of the healthcare infrastructure development in GCC post-pandemic.

[00:08:00] The role of expats in the Middle East's healthcare transformation.

[00:10:00] Public-private partnerships as key opportunities.

[00:12:00] Cultural considerations for startups in the GCC.

[00:14:00] Misconceptions about the Middle Eastern healthcare market.

[00:18:00] Building long-term relationships in business.

[00:20:00] Navigating diverse cultural communication in healthcare.

[00:24:00] Comparing the entrepreneurial spirit in the Middle East with the U.S. and Europe.

[00:28:00] Strategic advice for healthcare entrepreneurs targeting the GCC.

[00:30:00] Importance of understanding regulations and digital maturity in MENA.

[00:32:00] Future potential in biotech and digital health in the GCC.

[00:36:00] The convergence of digital health and biotech.

In the last few years, we've witnessed a whirlwind of developments in the world of Digital Therapeutics (DTx) - from FDA approvals sparking optimism for the industry, to the establishment of regulatory frameworks in countries like Germany, France, and Belgium.
However, in 2023, the industry faced a stark reality check, marked by the fall of some key players and healthcare systems' hesitancy towards embracing and financing these innovations. This turbulence has reshaped strategies and raised critical questions about the future of DTx.
🔍 In this episode learn more about:
📊 The current state of the DTx industry in 2024,
🗣️ Key debates of digital therapies industry players,
🌐 Advocacy efforts pushing the boundaries for global adoption,
🚀 Strategies to accelerate the integration of digital therapies worldwide.

Newsletter: fodh.substack.com
Website: www.facesofdigitalhealth.com

Patient-reported outcomes (PROs) have become increasingly integral in healthcare for assessing the effectiveness of treatments from the patient's perspective. It sounds like a reasonable step in improving clinical research and care provision, but gathering data can be more difficult then you may think. It isn't easy to get to marginalized communities. There are language barriers in collecting data. There are cultural aspects that impact responses. So, how can you design useful electronic solutions for patient-reported outcomes? Hear from Mustafa Ali Syed, Researcher at the Manchester Academic Health Science Centre, The University of Manchester, and Ben James, Co-founder/Chief Design Officer at uMotif - ePRO, an engagement platform designed to power clinical and real-world research. Both are co-authors of a recently published paper titled Exploring the Cross-cultural Acceptability of Digital Tools for Pain Self-reporting.

www.facesofdigitalhealth.com
Newsletter: https://fodh.substack.com/

Show notes:
00:00:00 Why Do PROs Matter?
00:04:00 Evolution of Data Collection
00:06:00 Importance of Diversity in Clinical Trials
00:08:00 Ethnicity, Culture, and Pain Perception
00:12:00 The Role of Technology in PROs
00:14:00 Designing Inclusive Digital Solutions
00:20:00 Challenges in Engaging Targeted Populations
00:22:00 Language and Communication Barriers
00:26:00 The Future of PRO Research

Did you know that Belgium has had an idea for classifying and validating digital therapeutics since 2018? A clear framework was formed with all main stakeholders involved - from health insurance to the industry. So why are we not hearing more about DTx in Belgium? In this discussion you will hear from Dr. Steven Vandeput -  he is the Advisor for Digital MedTech and Services & Technologies Home Assistance in Belgium; he is managing the mHealthBelgium portal and, since 2019, has been a representative for beMedTech, the sector federation that represents the industry of medical technologies in Belgium. 
Website: www.facesofdigitalhealth.com
Newsletter: https://fodh.substack.com/

Show notes:
00:00 - Introduction
01:45 - Digital Therapeutics in Belgium
03:50 - Belgium's Healthcare Framework Development
06:00 - The Validation Pyramid and Reimbursement System
08:00 - Fate of Pilot Projects and Their Impact
10:00 - Utilization of mHealth Belgium Portal
12:00 - Challenges in Reimbursement and Financing
14:00 - Prospects for Digital Therapeutic Companies
16:00 - Belgium's Approach to Financing Digital Health
18:00 - Anticipations for the Digital Health Field
20:00 - The Evolving European Frameworks
22:00 - Impact of Political Decisions and Healthcare System Integration
24:00 - The Future of mHealth Belgium Platform

The field of oncology treatments is advancing very fast with innovative therapies and approaches on the market every day. It can get very tricky to support these therapies from an IT perspective, which is what you will hear more about in this discussion. I spoke with Anish Patankar, SVP and GM of Elekta’s Oncology Software Solutions, and we discusses:

How to go about the US hospital market, 

Development in software for oncology treatments,

Challenges in scaling healthcare IT software across markets. 


Newsletter: https://fodh.substack.com/
www.facesofdigitalhealth.com

Show notes:
[00:00:00] Introduction to Elekta
[00:02:00] Elekta's Global Presence
[00:04:00] US Market Focus
[00:06:00] Growth in Developing Countries
[00:08:00] Segmentation and Technology Adoption in the US
[00:10:00] Untapped Needs and Opportunities in the US
[00:12:00] Elekta's Use of AI
[00:14:00] Patient Feedback and Clinical Decision Making
[00:18:00] Navigating Legacy Software in Healthcare IT
[00:20:00] Modernization and Customer Satisfaction
[00:22:00] Global Standardization and Regulation Challenges
[00:24:00] Interoperability and Open Ecosystem
[00:26:00] Future of Oncology Market Development: the interplay between medications and radiation, and the potential of theranostics.
[00:28:00] Exciting Technologies in Healthcare Beyond Oncology: personalized healthcare, digital twins
[00:30:00] Cautions for the Future: The critical debate on the balance between innovation speed and safety, particularly with generative AI.