#042 Dr. Valter Longo on Resetting Autoimmunity and Rejuvenating Systems with Prolonged Fasting & the FMD

Dr. Valter Longo

Dr. Longo is the current director of the longevity institute at the University of Southern California and also director of the Oncology and Longevity Program at the Institute of Molecular Oncology Foundation in Milan, Italy.

Dr. Longo’s research focuses understanding the biological mechanisms that regulate the aging process, the role of fasting and diet in longevity and healthspan in humans as well as metabolic fasting therapies for the treatment of human diseases. In this episode, we discuss...

• (00:00) Introduction
• (09:30) Defining fasting
• (16:10) Insulin/growth hormone axis and aging
• (21:37) Growth hormone deficiency protects from some diseases
• (30:55) Fasting vs a ketogenic diet for cancer
• (40:13) The fasting-mimicking diet (FMD)
• (48:28) "Yo-yo" fasting once per month
• (52:21) Fasting does not reduce muscle mass 
• (57:03) Autophagy and apoptosis are our repair mechanisms
• (01:02:33) Refeeding is necessary to rebuild healthy cells
• (01:05:31) Top 5 biomarkers of healthy aging

If you’re interested in learning more, you can read the full show notes here.

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