Empowered Patient Podcast

Karen Jagoda
  • 4.9 (18)
  • Medicine
  • Updated Daily

Empowered Patient Podcast with Karen Jagoda is a window into the latest innovations in digital health, the changing dynamic between doctors and patients, and the emergence of precision medicine. The show covers such topics as aging in place, innovative uses for wearables and sensors, advances in clinical research, applied genetics, drug development, and challenges for connected health entrepreneurs.

  1. Aug 26 ·  Bonus

    Red Light Therapy for Healing and Chronic Conditions with Dr. Carl Rothschild and Eddie Brown Trifecta Light Technologies TRANSCRIPT

    Dr. Carl Rothschild, CEO and Founder, and Eddie Brown, COO of Trifecta Light Technologies, discuss the therapeutic applications of red light and near-infrared therapy by bathing the entire body with these specific light wavelengths. The technology has FDA clearance for fat reduction and healing and clinical research indicates efficacy in neurological disorders and musculoskeletal conditions. The devices are user-friendly and have also been shown to support athletes in recovery and the beauty industry for skin health. Dr. Carl explains, "And so what has since subsequently been learned is that this light of both red, and we also use near infrared, which is even more powerful and more healing; what it does is it affects every cell that we can get to in your body. And the more cells we can get to, the better. That's why you want deep-penetrating, medical-grade beds that can penetrate as much as possible to affect as many cells." Eddie elaborates, "With any kind of red light item, usually the bed, the lights, they're FDA registered, which means basically it's an infrared heat source. What we did with our bed, nobody else was able to do this. Not to say that in the future they're not going to, but right now we're kind of ahead of the curve, the only ones who have it. We've had FDA clearance for ours."   #TrifectaLight #RedLightTherapy #Photobiomodulation #MitochondrialHealth #MetabolicHealth #ChronicCare #SportsMedicine #RegenerativeMedicine Trifectalight.com Listen to the podcast here

  2. Aug 26

    Red Light Therapy for Healing and Chronic Conditions with Dr. Carl Rothschild and Eddie Brown Trifecta Light Technologies

    Dr. Carl Rothschild, CEO and Founder, and Eddie Brown, COO of Trifecta Light Technologies, discuss the therapeutic applications of red light and near-infrared therapy by bathing the entire body with these specific light wavelengths. The technology has FDA clearance for fat reduction and healing and clinical research indicates efficacy in neurological disorders and musculoskeletal conditions. The devices are user-friendly and have also been shown to support athletes in recovery and the beauty industry for skin health. Dr. Carl explains, "And so what has since subsequently been learned is that this light of both red, and we also use near infrared, which is even more powerful and more healing; what it does is it affects every cell that we can get to in your body. And the more cells we can get to, the better. That's why you want deep-penetrating, medical-grade beds that can penetrate as much as possible to affect as many cells." Eddie elaborates, "With any kind of red light item, usually the bed, the lights, they're FDA registered, which means basically it's an infrared heat source. What we did with our bed, nobody else was able to do this. Not to say that in the future they're not going to, but right now we're kind of ahead of the curve, the only ones who have it. We've had FDA clearance for ours."  #TrifectaLight #RedLightTherapy #Photobiomodulation #MitochondrialHealth #MetabolicHealth #ChronicCare #SportsMedicine #RegenerativeMedicine Trifectalight.com Download the transcript here

  3. Aug 26 ·  Bonus

    Next-Generation Antivirals to Tackle Norovirus with James Sapirstein CoCrystal Pharma TRANSCRIPT

    James Sapirstein, CEO of CoCrystal Pharma, is developing a platform of antiviral therapies to treat norovirus, influenza and other viruses.  Norovirus, commonly transmitted on cruise ships and in dormitories, currently lacks effective vaccines or treatments. CoCrystal's oral small-molecule approach aims to treat active infections by reducing viral shedding duration and provide prophylactic prevention using a novel mechanism that targets viral entry points to prevent replication. James explains, "At CoCrystal Pharma, we have a platform of antiviral programs. The first program is for norovirus, and we have another program for influenza A. And then we also have a platform for rhinovirus, which is also many times referred to as the common cold. There's really not much out there."   "Norovirus is commonly known on cruise ships and in dormitories, college dormitories, and really it spreads by touch. That's why, when cruise ships have an outbreak of norovirus, if people haven't washed their hands or they touch an area where someone has touched that area before with active norovirus, they can get infected. And because people touch their faces over a thousand times, literally in a couple of hours, it's easy to transmit the virus."   "But there's also chronic norovirus, which people don't really talk about much because it's mostly in the nursing homes and assisted living areas, where some of these patients really suffer, and they're septic for a very long period of time. And they're not tested to see if they have norovirus because they have so many other health issues that people just aren't tested correctly." "Most antivirals, for the most part, work on the RNA. They cleave off the RNA, or they cleave off the cell membrane so that it doesn't replicate and the virus dies off. For us, it's much more specific. We like to call it a pocket where the virus enters the cell. We design a drug to specifically kill the virus at certain aspects within the virus, and then it doesn't allow it to replicate. And that's the way it's designed." #CoCrystalPharma #Norovirus #Antivirals #DrugDiscovery #InfectiousDiseases cocrystalpharma.com  Listen to the podcast here

  4. Aug 26

    Next-Generation Antivirals to Tackle Norovirus with James Sapirstein CoCrystal Pharma

    James Sapirstein, CEO of CoCrystal Pharma, is developing a platform of antiviral therapies to treat norovirus, influenza and other viruses.  Norovirus, commonly transmitted on cruise ships and in dormitories, currently lacks effective vaccines or treatments. CoCrystal's oral small-molecule approach aims to treat active infections by reducing viral shedding duration and provide prophylactic prevention using a novel mechanism that targets viral entry points to prevent replication. James explains, "At CoCrystal Pharma, we have a platform of antiviral programs. The first program is for norovirus, and we have another program for influenza A. And then we also have a platform for rhinovirus, which is also many times referred to as the common cold. There's really not much out there."   "Norovirus is commonly known on cruise ships and in dormitories, college dormitories, and really it spreads by touch. That's why, when cruise ships have an outbreak of norovirus, if people haven't washed their hands or they touch an area where someone has touched that area before with active norovirus, they can get infected. And because people touch their faces over a thousand times, literally in a couple of hours, it's easy to transmit the virus."   "But there's also chronic norovirus, which people don't really talk about much because it's mostly in the nursing homes and assisted living areas, where some of these patients really suffer, and they're septic for a very long period of time. And they're not tested to see if they have norovirus because they have so many other health issues that people just aren't tested correctly." "Most antivirals, for the most part, work on the RNA. They cleave off the RNA, or they cleave off the cell membrane so that it doesn't replicate and the virus dies off. For us, it's much more specific. We like to call it a pocket where the virus enters the cell. We design a drug to specifically kill the virus at certain aspects within the virus, and then it doesn't allow it to replicate. And that's the way it's designed." #CoCrystalPharma #Norovirus #Antivirals #DrugDiscovery #InfectiousDiseases cocrystalpharma.com Download the transcript here

  5. Aug 25 ·  Bonus

    How Telehospitalists Are Expanding Capacity and Coverage for Hospitals with Dr. Claire Smith SCP Health TRANSCRIPT

    Dr. Claire Smith, a regional medical officer at SCP Health and a practicing hospitalist in Missouri, highlights how virtual hospitalists are transforming healthcare by providing 24/7 physician collaboration to support onsite teams, particularly in rural hospitals and during patient surges. Implementing telehospitalists can play a critical role in reducing clinician burnout, improving access to physician expertise, and enhancing emergency department efficiency. Integrating telehospitalists into a care model shows potential to reshape workforce demographics and improve the ability to meet unpredictable demands. Claire explains, "So a hospitalist is typically an internal medicine or family medicine-trained physician who focuses the entirety of their career on hospital medicine. So, taking care of hospitalized patients. They are focused on the end-to-end experience of a patient who is hospitalized. So they are integral in the admission from the emergency department, from the time it is determined the patient needs care within the hospital to the time that they are discharged to their next site of care, whether that be home, a skilled nursing facility, etc. So hospitalists do not focus on outpatient medicine. They collaborate with primary care physicians and care for hospitalized patients."   "And what we are seeing is that we are now integrating virtual hospitalists or telehospitalists into workflows to support teams in a variety of situations, including resource shortages or temporary surges in the patient population, so that we can best support the onsite teams and patients."   "What we see is that telehospitalists are being utilized when demands exceed onsite capacities, as well as in those rural situations where resources are more scarce. So a telehospitalist changes the dynamic from really an occasional ad hoc contact with advanced practitioners who may be supporting rural practice hospital medicine to reliable collaboration."  #SCPHealth #Telehospitalist #RuralHealth #HospitalMedicine #Telemedicine #HealthcareInnovation #ClinicianWellbeing #VirtualCare #24x7Coverage #PatientCare scphealth.com Listen to the podcast here

  6. Aug 25

    How Telehospitalists Are Expanding Capacity and Coverage for Hospitals with Dr. Claire Smith SCP Health

    Dr. Claire Smith, a regional medical officer at SCP Health and a practicing hospitalist in Missouri, highlights how virtual hospitalists are transforming healthcare by providing 24/7 physician collaboration to support onsite teams, particularly in rural hospitals and during patient surges. Implementing telehospitalists can play a critical role in reducing clinician burnout, improving access to physician expertise, and enhancing emergency department efficiency. Integrating telehospitalists into a care model shows potential to reshape workforce demographics and improve the ability to meet unpredictable demands. Claire explains, "So a hospitalist is typically an internal medicine or family medicine-trained physician who focuses the entirety of their career on hospital medicine. So, taking care of hospitalized patients. They are focused on the end-to-end experience of a patient who is hospitalized. So they are integral in the admission from the emergency department, from the time it is determined the patient needs care within the hospital to the time that they are discharged to their next site of care, whether that be home, a skilled nursing facility, etc. So hospitalists do not focus on outpatient medicine. They collaborate with primary care physicians and care for hospitalized patients."   "And what we are seeing is that we are now integrating virtual hospitalists or telehospitalists into workflows to support teams in a variety of situations, including resource shortages or temporary surges in the patient population, so that we can best support the onsite teams and patients."   "What we see is that telehospitalists are being utilized when demands exceed onsite capacities, as well as in those rural situations where resources are more scarce. So a telehospitalist changes the dynamic from really an occasional ad hoc contact with advanced practitioners who may be supporting rural practice hospital medicine to reliable collaboration."  #SCPHealth #Telehospitalist #RuralHealth #HospitalMedicine #Telemedicine #HealthcareInnovation #ClinicianWellbeing #VirtualCare #24x7Coverage #PatientCare scphealth.com Download the transcript here

  7. Aug 25 ·  Bonus

    Using Neuroimaging and Deep Brain Stimulation to Provide Durable Relief for Severe Treatment-Resistant Depression with Dr. Mark George TRANSCEND Study TRANSCRIPT

    Dr. Mark George is the principal psychiatric investigator of Abbott's TRANSCEND study and also a professor of psychiatry at MUSC Health Institute of Psychiatry.  The TRANSCEND study represents a paradigm shift in depression treatment by investigating deep brain stimulation as a potential solution for treatment-resistant depression. This research involves surgically implanting a device that delivers targeted electrical stimulation to specific brain circuits. By reframing depression as a brain disorder rather than a chemical imbalance, this study emphasizes the biological nature of depression, offering an alternative to a condition with limited options. Mark explains, "There are a lot of people, unfortunately, maybe a quarter of the people with depression who lead lives of misery where the medications and talking just don't get them back on their game. And so that's what we call treatment-resistant depression. And that's where I've spent my career trying to come up with new treatments."   "Well, so if the medications aren't working, you can try even more medicines, but the odds go way down. So there's a whole class of things where we actually stimulate the brain to try to, non-invasively and not using a pill, get in and change circuits in the brain. And those have started to really transform the care of treatment-resistant depression. There are several of them that are both non-invasive, and then others that are invasive."  "But the real holy grail would be for us to find the circuit or the spot in the brain and be able to put something there and then fix it. And then there you go, you live your life, and it would not be a pill that you have to take every day. And it would not have systemic side effects like medications. It wouldn't cause weight gain, sexual side effects, those kinds of things. So the real interest in the deep brain stimulation study that Abbott TRANSCEND is: "Could we stick a wire in the area of the brain that's not working right and pass very, very small amounts of electricity and really wake somebody up and get them out of their depression?" #Abbott #DBS #TRANSCENDstudy  #TRD #TreatmentReistantDepression TRANSCEND  Listen to the podcast here

  8. Aug 25

    Using Neuroimaging and Deep Brain Stimulation to Provide Durable Relief for Severe Treatment-Resistant Depression with Dr. Mark George TRANSCEND Study

    Dr. Mark George is the principal psychiatric investigator of Abbott's TRANSCEND study and also a professor of psychiatry at MUSC Health Institute of Psychiatry.  The TRANSCEND study represents a paradigm shift in depression treatment by investigating deep brain stimulation as a potential solution for treatment-resistant depression. This research involves surgically implanting a device that delivers targeted electrical stimulation to specific brain circuits. By reframing depression as a brain disorder rather than a chemical imbalance, this study emphasizes the biological nature of depression, offering an alternative to a condition with limited options. Mark explains, "There are a lot of people, unfortunately, maybe a quarter of the people with depression who lead lives of misery where the medications and talking just don't get them back on their game. And so that's what we call treatment-resistant depression. And that's where I've spent my career trying to come up with new treatments."   "Well, so if the medications aren't working, you can try even more medicines, but the odds go way down. So there's a whole class of things where we actually stimulate the brain to try to, non-invasively and not using a pill, get in and change circuits in the brain. And those have started to really transform the care of treatment-resistant depression. There are several of them that are both non-invasive, and then others that are invasive."  "But the real holy grail would be for us to find the circuit or the spot in the brain and be able to put something there and then fix it. And then there you go, you live your life, and it would not be a pill that you have to take every day. And it would not have systemic side effects like medications. It wouldn't cause weight gain, sexual side effects, those kinds of things. So the real interest in the deep brain stimulation study that Abbott TRANSCEND is: "Could we stick a wire in the area of the brain that's not working right and pass very, very small amounts of electricity and really wake somebody up and get them out of their depression?" #Abbott #DBS #TRANSCENDstudy  #TRD #TreatmentReistantDepression TRANSCEND  Download the transcript here

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About

Empowered Patient Podcast with Karen Jagoda is a window into the latest innovations in digital health, the changing dynamic between doctors and patients, and the emergence of precision medicine. The show covers such topics as aging in place, innovative uses for wearables and sensors, advances in clinical research, applied genetics, drug development, and challenges for connected health entrepreneurs.

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