Dr Jack Cush reviews the news, journal reports and FDA approvals
RheumNow Podcast – Do More DMARDs Mean More Switching? (9.17.2021)
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In this episode, Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com
Metanalysis of JAK inhibition (tofacitinib & ruxolitinib) in alopecia areata - 12 studies, 346 Pts, Rx success (using SALT50 resp) was 66%, not influenced by age, sex, subtype. Alopecia recurrence seen w/in 3 mos of JAK D/C (in74%) https://t.co/CBSy4Kci80
Population study shows risk of H. Zoster in adults to be high among bDMARD and CTX, also increased w/ AZA and HCQ but not MTX SSZ or LEF users. Data from 254065, 1,826311 Pt-Yrs F/U, 6295 new DMARD users, 17024 incident HZ https://t.co/1TeOAWN9LB
MMWR reports that during the COVID Delta variant era, Vaccination against COVID-19: - Reduces risk of COVID-19 infection 5X - Reduces risk of COVID-19 Hospitalization ⋗10X - Reduces risk of COVID-19 DEATH 10X https://t.co/rMRY84xX5F
Study of 265 students w/ a positive COVID-19 test looked at 378 close contacts. Infx rates w both persons masked -7.7%, but when unmasked-32.4% (aORs = 4.9) https://t.co/fYdH33JbWR
Effect of Diet on COVID Outcomes Probenecid, an OAT3 inhibitor, has inhibitory effects on RNA viruses (influenza, RSV) & decreases ACE2 expression. May have utility in COVID-19 as it was shown to inhibit SARS-CoV-2 replication in animal modelshttps://t.co/MClSjpqpSa
Mease and colleagues have catalogued the current practices assessed in the CORRONA registry, noting that increased DMARD switching and decreased time on a given therapy by US physicians. https://t.co/cIWZw6KsuI
A retrospective study of systemic sclerosis patients shows that acute hospitalization and mortality were not uncommon and were often linked to SSc-related lung disease. #RheumNow https://t.co/s5wSlndTrt
Cases and Questions (AKA Back Talk) “What treatment do you use after 2 years of teraparitide in a woman with a hx of OP, spiral fracture while on a bisphosphonate”? Forteo PI. “Do you have any inside info on the vaccines for COVID-19 during pregnancy?” OCOG Statement “Status of the Tocilizumab Shortage”? Genentech Statement “How would you treat polyarthritis in a renal transplant patient?”
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RheumNow Podcast – High Science and Future Treatments (9.10.2021)
Dr. Jack Cush Reviews the news and journal articles from the past week on RheumNow.com
Rheumatologist Views on new FDA JAK inhibitor Boxed Warnings
Dr. Jack Cush is joined by Drs. Kathryn Dao (Dallas), Rachel Tate (Palm Beach), William Shergy (Huntsville) and Jeffrey Sparks (Boston)
RheumNow Podcast – JAK Inhibitor Warnings from the FDA (9.3.2021)
Dr Jack Cush reviews the news, journal articles and FDA warnings from the past week on RheumNow.com
Expert Panel Inital Views on FDA Warnings for JAK Inhibitors
Dr. Jack Cush is joined by Drs. Roy Fleischmann (Dallas), Allan Gibofsky (NYC), and Artie Kavanaugh (San Diego)
RheumNow Podcast – COVID Marching Amidst the Madness (8.27.2021)
Dr. Jack Cush reviews the news, journal reports and cautions regarding COVID-19
Dr. Cush and The Rheumnow podcast deliver best 15 minutes of education I get all week. A must listen for rheumatologists. Thanks for all the clinical pearls.
Best way to learn and stay up to date!!!!! It is a must for any practicing rheumatologist that wants to stay current and better equipped to care for our patients.
Thank you Dr Cush!
Thank you for the podcast! Best way of learning for me.