64 episodes

Join Dr. Robert Pastore and his co-host Lexie (@lexircise) as they discuss and clarify nutritional and neurochemical science. Dr. Pastore is also joined by guests from backgrounds of all types – from all-star athletes, to top trainers and coaches, to scientists and researchers - and dives deeply into the science behind optimizing performance and longevity.

Dr. Pastore is a Certified Nutrition Specialist, and holds an MS in Human Nutrition from Eastern Michigan University and a Ph.D. in Biomedical Informatics, Nanomedicine and Clinical Informatics from Rutgers University. Dr. Pastore has spent over a decade practicing "applied biochemistry" as he treats some of the world’s greatest athletes from the NHL, MLB, NFL, Olympics and endurance sports, as well CEOs and top executives of Fortune 500 companies.

The Pastore Podcast Dr. Robert Pastore, PhD, CNS

    • Health & Fitness
    • 5.0, 3 Ratings

Join Dr. Robert Pastore and his co-host Lexie (@lexircise) as they discuss and clarify nutritional and neurochemical science. Dr. Pastore is also joined by guests from backgrounds of all types – from all-star athletes, to top trainers and coaches, to scientists and researchers - and dives deeply into the science behind optimizing performance and longevity.

Dr. Pastore is a Certified Nutrition Specialist, and holds an MS in Human Nutrition from Eastern Michigan University and a Ph.D. in Biomedical Informatics, Nanomedicine and Clinical Informatics from Rutgers University. Dr. Pastore has spent over a decade practicing "applied biochemistry" as he treats some of the world’s greatest athletes from the NHL, MLB, NFL, Olympics and endurance sports, as well CEOs and top executives of Fortune 500 companies.

    On Refractory Celiac Disease

    On Refractory Celiac Disease

    Continuing with topics around Celiac Disease Awareness Month, Dr. Pastore discusses a condition that some diagnosed celiacs are still faced with - refractory celiac disease.

    He covers what it is, how it’s diagnosed, how common it is amongst diagnosed celiac disease patients, the signs and symptoms to look out for, causes, treatments, secondary food reactions and what to discuss with your physician.

    • 44 min
    On Tissue Transglutaminse and TTG IgA

    On Tissue Transglutaminse and TTG IgA

    Dr. Pastore covers a well-known, yet not well-understood diagnostic marker of celiac disease -  tissue transglutaminase (TTG). He covers the function TTG plays as an enzyme, how TTG affects gluten and shares vital information about various TTG blood tests (TTG IgA and TTG IgG) for those looking for a diagnosis, and for the diagnosed celiac wanting to monitor their progress.
    Show notes:
    https://drrobertpastore.com/podcasts/063-tissue-transglutaminase

    • 43 min
    On Celiac Disease Awareness Month

    On Celiac Disease Awareness Month

    May is Celiac Disease Awareness Month, and Dr. Pastore covers important and relevant information on all-things celiac disease including statistics, symptoms, the history of the disease and how to go about being diagnosed, as 83% of those with the disease are not.
    Show notes:
    https://drrobertpastore.com/podcasts/celiac-disease-awareness-month-2020

    • 50 min
    Ask Dr. Pastore: On Gut Health & Digestion

    Ask Dr. Pastore: On Gut Health & Digestion

    Dr. Pastore answers questions asked by Lexie’s fitness training team around gut health, digestion, food intolerances, candida, h-pylori, probiotics, and gut microbiota. 
     
    Show notes: 
    https://drrobertpastore.com/podcasts

    • 1 hr 7 min
    On Sleep & Immunity

    On Sleep & Immunity

    Dr. Pastore discusses the vital role sleep plays in immunity, how lack of sleep and poor quality sleep can lower your immune system, sleep duration guidelines for optimal health and steps you can take to improve your sleep. 
     
    What is “poor” sleep [1:00]
    Quality sleep for adults 7-9 continuous, uninterrupted hours of sleep per night  Likely not possible for parents, like Dr. Pastore  Teenagers require 8-10 continuous, uninterrupted hours of sleep per night  6.5 - 7 hours for teenagers can have same effect as being inebriated  Sleep science still needs much more research  Those staying home & safe during COVID-19 can cause COVID-19 dreams Intense/horror dreams due to inability to normalize stress/anxiety during the day  
    Lack of quality sleep mentioned above is directly associated with higher likelihood of being sick after being exposed to a virus [3:55]
    Studies on common cold  Lack of sleep or disrupted sleep increases risk of getting a virus   
    Lack of sleep impacted how fast you recover if you do get sick [4:40]
    Dr. Pastore treating patients & working with other doctors treating patients with COVID-19, those recovering slower & have the virus longer have worse sleep  21 & 23 days of having the active COVID-19 infection  Seen faster COVID-19 recovery of 9 days with better, quality sleep   
    Quality sleep needs to be uninterrupted [7:05]
    Difficult for parents waking up for children 7-9 for adults, 8-10 hours for teenager straight   
    Long-term poor quality sleep increase risk of obesity & diseases that further the risk for infections [9:05]
      Medical fact: poor sleep causes cardiovascular disease, diabetes & obesity  Cardiovascular disease, diabetes & obesity increase risk for infections such as COVID-19 or regular flu  Inflammasome is byproduct of being overweight & obesity  Proinflammatory response that can lower immune system  Quality sleep drastically improves fat loss progress  Lack of sleep (as little as 2-3 nights in a row) - cells become temporarily insulin resistant which causes elevation in glucose, can lead to weight gain & fat storage  Chronic lack of sleep can make cells permanently insulin resistant  Quality sleep improves cell-signalling communication between insulin receptor cells & GLUT receptors to let glucose into the cells   
    Poor sleep lowers your immune system, makes it longer to recover from a virus, increases risk of diseases that can further lower the immune system, and can worsen health if pre-existing disease exists [13:00] 
    We’re all biochemically & genetically unique  Knowing genetics, medical history, biological markers, calcium score   
    Why does decreased sleep lower the immune system? [14:55]
    Sleep supports & enhances the initiation of an adaptive immune system response  Adaptive immune system response process: Trouble maker / invading antigen / virus invading body Human immune system takes up antigen & appropriates it Breaks apart the antigen & presents fragments of antigen to T Helper Cells T Helper Cells signal cytokines Interleukin 12 Interleukin 12 calls in T-Helper Cell One Response, supports antigen specific T-Cells T-Helper Cell 1 Response starts B-Cell production of antibodies to always be able to recognize the invading antigen / virus  If the invading antigen is presented in the body again, the body will attack it  Produced in the lymph nodes  Vaccines are a great example of adaptive immunity, producing herd immunity  Sleep turns this response on, lack of sleep turns it off Immune cannot identify the invading antigen  Sleep deprived hepatitis A vaccine patients vs quality sleep hepatitis A vaccine patients Poor sleep patients did not have amplified adaptive immune system response to vaccine Parents typically lose hundreds of hours of sleep   
    Prescription medications to imp

    • 56 min
    On New Acute Symptoms of Celiac Disease & Gluten Exposure for Celiacs

    On New Acute Symptoms of Celiac Disease & Gluten Exposure for Celiacs

    As covered in previous podcasts, celiac disease can have many symptoms beyond gastrointestinal issues and looking skinny/malnourished. In this episode, Dr. Pastore discusses a study that revealed two new acute, non-classic symptoms that could be the only sign of celiac disease - nausea and vomiting within 2-4 hours of eating. Both symptoms typically originate in the stomach, whereas classic celiac symptoms are caused due to damage of the small intestine. He covers what is causing these symptoms and what to do if you experience them.
     
    Links mentioned:
     
    Nausea & Vomiting after Gluten Exposure
    https://celiac.org/glutenexposuremarkers/
     
    Full vaccine study:
    https://celiac.org/main/wp-content/uploads/2020/03/NexVax2-Study.pdf
     

    • 32 min

Customer Reviews

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3 Ratings

3 Ratings

leah_nay ,

Life saver!!

I am 35 years old and recently diagnosed with celiac. I had no clue what that meant and it turns out, neither did my doctor. There is so much important information about celiac in this podcast. It has really helped me learn about and understand the disease. I really appreciate it!!

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