39 episodes

Unite 2 Fight Paralysis exists to unite and empower the international spinal cord injury community to cure paralysis through advocacy, education, and support for research. Get Educated and Get Involved.

U2FP CureCast Matthew Rodreick & Kate Willette

    • Education
    • 5.0, 4 Ratings

Unite 2 Fight Paralysis exists to unite and empower the international spinal cord injury community to cure paralysis through advocacy, education, and support for research. Get Educated and Get Involved.

    CureCast Epsiode 39: Dr. Murray Blackmore

    CureCast Epsiode 39: Dr. Murray Blackmore

    "What is the goal here? What are we trying to do?...and to me it still is and has always been to basically restore near normal function to people that have chronic spinal cord injury…that’s what I wanna talk about….what I’ve learned is that I have to start with that. And I have to start with the following sentence, which is: I believe that’s possible and what I wanna do is to be a part of making that happen.”

    This is an excerpt from Jason and Matthew’s interview with Dr. Murray Blackmore from Marquette University in Milwaukee Wisconsin. Dr. Blackmore’s research is immersed in identifying candidate genes toward nerve regeneration for Spinal Cord Injury.

    We discuss how spinal cord injury invited itself into Murray’s family from a devastating car accident in his early teens where his mother suffered a C5 injury. And how this led to Murray’s work and passionate efforts to discover a meaningful path to curing paralysis.

    After Murray provides a primer on genetics as a starting point to explain the complex methodologies applied in his lab to test gene candidates we have a bit of a sidebar conversation regarding the intersection of research and passion and follow that with some of Murray's 'pie in the sky' ideas for creating change in the larger research process. Check it out!

    Bio:
    Dr. Blackmore received his undergraduate degree from Stanford University, and his graduate degree in neuroscience from the University of Minnesota. During his postdoctoral training at the Miami Project to Cure Paralysis, Dr. Blackmore studied axon regeneration and adopted High Content Screening methods to identify new gene targets to promote neural repair. Later, as a Research Assistant Professor at the Miami Project, Dr. Blackmore used a gene therapy approach to test these new gene targets for the ability to promote axon regeneration in the injured spinal cord. Dr. Blackmore is continuing this line of research at Marquette University, using viral delivery of genes to injured neurons in rodent models of spinal injury in order to foster repair.

    • 1 hr 11 min
    CureCast Episode 38: An Interview with NervGen Pharma's Paul Brennan & Harold Punnett

    CureCast Episode 38: An Interview with NervGen Pharma's Paul Brennan & Harold Punnett

    Jason and Matthew interview Dr. Harold Punnett (co-founder and member of the Board of Directors) and Paul Brennan (President and CEO) from NervGen Pharma. They discuss how Dr. Punnett’s daughter-in-law’s Spinal Cord Injury led to the connection with Dr. Jerry Silver (click the link to hear more about the science from episode 19 with Dr. Jerry Silver) and eventually the founding of the company, their proprietary NVG291 (also known as intracellular sigma peptide or ISP) and their hopes for its use in treating SCI and other CNS disorders.

    Dr. Harold Punnett: Dr. Punnett, co-founder of NervGen, is an accomplished angel investor who has been the director of multiple start-up companies. As a dental surgeon with a practice in British Columbia, Canada, he has extensive knowledge of medicine and physiology, including cell biology. Along with this knowledge, he has a deep passion for those suffering from spinal cord injury and other nerve-related challenges. Dr. Punnett is a Member of the College of Dental Surgeons of British Columbia, Member of the British Columbia Dental Association and Member of the Canadian Dental Association. He received his doctorate degree from the University of British Columbia.

    Paul Brennan: Paul Brennan has over 30 years of experience in the pharmaceutical and biotech industries working in leadership roles in general management, corporate strategy, commercial planning, business development and regulatory affairs in Canada, Sweden, the United Kingdom, and the United States. Most recently Mr. Brennan’s experiences include senior business development and management positions in various biotech companies, including Aquinox Pharmaceuticals, Arbutus Biopharma, Aspreva Pharmaceuticals, and AnorMED Inc. Mr. Brennan has a comprehensive list of business development and licensing transactions, totalling over $3 billion in value: he played key roles in the merger of Tekmira Pharmaceuticals and OnCore BioPharma to create Arbutus Biopharma, in the sale of Aspreva Pharmaceuticals to Vifor Pharma for $915 million and in the sale of AnorMED to Genzyme for $580 million. Prior to working in biotech Mr. Brennan held senior roles in Business Development and Regulatory Affairs at AstraZeneca. Mr. Brennan holds a MSc in Physiology, and a BSc (Hons) in Life Sciences from Queen’s University in Kingston, Ontario

    • 1 hr 18 min
    CureCast Epsiode 37: Interview with Drs. Sasha Rabchevsky and Michael Lane

    CureCast Epsiode 37: Interview with Drs. Sasha Rabchevsky and Michael Lane

    Jason and Matthew interview Dr. Sasha Rabchevsky from the University of Kentucky and Dr. Michael Lane from the Drexel College of Medicine. They are both Spinal Cord Injury researchers, and if interested in the specifics of their research you can find earlier podcast interviews with them here. In this interview we talk about how the COVID-19 shutdown has affected the research effort and how researchers and institutions are adapting. We then explore some ideas about what we might see or anticipate on the other end of the shutdown.

    • 1 hr 3 min
    Episode 36: Kelsey Peterson on Winning Big Funding from ITVS Open Call for her Documentary

    Episode 36: Kelsey Peterson on Winning Big Funding from ITVS Open Call for her Documentary

    Matthew talks with Kelsey Peterson, the woman behind the documentary film SUBMERGED - formerly titled “The Cure Map”. Matthew and Kelsey talk about her pathway to advocacy and the genesis of the Cure Map project, the recent announcement of being the recipient of the highly competitive ITVS Open Call award, the effects of the COVID-19 troubles and lots more.

    Follow Kelsey on social media here:
    https://www.facebook.com/submergeddocumentaryfilm/
    https://www.instagram.com/submergedfilm/
    https://www.youtube.com/channel/UC0uh96WZU_X46JIWSCqM6bw

    • 1 hr 12 min
    Episode 35: An Interview with Sam Schmidt, Founder of Conquer Paralysis Now

    Episode 35: An Interview with Sam Schmidt, Founder of Conquer Paralysis Now

    Jason and Matthew interview Conquer Paralysis Now founder, Sam Schmidt. We discuss Sam’s history as a race car driver, his injury, the genesis for the foundation and his recent project Driven, an Activity Based Fitness center in Las Vegas Nevada.

    Please reach out to us at curecast@u2fp.org

    • 1 hr 12 min
    CureCast Episode 34: A Conversation with Jason Stoffer and Kate Willette

    CureCast Episode 34: A Conversation with Jason Stoffer and Kate Willette

    In Epsiode 34 of U2FP's CureCast podcast, we introduce Jason Stoffer. We talk with Jason about who he is, where he hails from and how he came to be the new co-host on the podcast. We also talk with Kate Willette, author of Don’t Call It a Miracle: The Movement To Cure Spinal Cord Injury, about her new projects. It's an intimate and wide-ranging conversation that we think you’ll enjoy. You can email us at curecast@u2fp.org We’d love to hear from you, and you can find out more about us at u2fp.org

    • 54 min

Customer Reviews

5.0 out of 5
4 Ratings

4 Ratings

Brad sci ,

Someone with SCI

This podcast is great. I appreciate the effort to continue the movement to cure paralysis. Unfortunately I feel as though a lot of the community/ medical field has given up on trying to find a cure and excepting things as they happen. We all deal with things in different ways, but anyone living with SCI knows how difficult life can be living with this. Never give up! I appreciate the the genuine spirits of the people that do this podcast along with all the medical professionals who work hard at trying to find a cure. Thank you!

borowiczd ,

An sci viewers perspective

Jason depiction of an individual with SCI viewing life being content was spot on for me. Thanks for sharing keep spreading love and knowledge.

jburda1 ,

Great discussion and diverse perspectives

Excellent cast on all aspects of spinal cord injury life, research, treatment and beyond. Great potential too!

Top Podcasts In Education