12 episodes

On this podcast, Christina Applegate and Jamie-Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

MeSsy with Christina Applegate & Jamie-Lynn Sigler Wishbone Production

    • Society & Culture
    • 4.9 • 2.5K Ratings

On this podcast, Christina Applegate and Jamie-Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

    Katie Couric

    Katie Couric

    This week, Christina and Jamie are joined by Katie Couric. They discuss the importance of community and honesty, why we need more collaboration over competition, the changing media landscape, and more. 
    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This show is sponsored by:
    Maybelline - If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    Lolavie -Get 15% off LolaVie with the code MESSY at https://www.lolavie.com/MESSY #lolaviepod 
    Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout visit cionic.com

    • 1 hr 12 min
    Jean Smart

    Jean Smart

    This week, Christina and Jamie are joined by Jean Smart. They share memories from when Christina and Jean worked together, and discuss taking back your power, embracing the quiet moments, her career trajectory, and much more.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This show is sponsored by:
    Maybelline- If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    Vuori -Get 20% off your FIRST purchase of the most comfortable and versatile clothing on the planet at vuori.com/MESSY
    Zoc Doc - Go to Zocdoc.com/MESSY and download the Zocdoc app for FREE. Then find and book a top-rated doctor today. 

    • 57 min
    Body Talk

    Body Talk

    This week, Christina and Jamie open up about their battles with eating disorders and self-esteem. They reflect on the moments that changed their lives, and discuss body dysmorphia, societal conditioning, how they each got to a healthier place, and more.
    *Trigger warning: discussion covers eating disorders and body image*

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    Maybelline: If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    BetterHelp: This episode is sponsored by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.”
    Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout visit cionic.com

    • 55 min
    How Did You Know?

    How Did You Know?

    This week, Christina and Jamie discuss giving up control, feeling judgement, and Jamie shares how she knew to get tested for MS. They also answer some listener questions.
    Parts of this episode were recorded in 2023.
    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    Maybelline: If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    Lume: Control Body Odor ANYWHERE with @lumedeodorant and get 15% off with promo code messy at LumeDeodorant.com! #lumepod
    Vuori: For our listeners, they are offering 20% off your FIRST purchase. Get yourself some of the most comfortable and versatile clothing on the planet at vuori.com/MESSY
    BetterHelp: This episode is sponsored by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.

    • 1 hr 5 min
    Jimmy Kimmel

    Jimmy Kimmel

    This week, Christina and Jamie are joined by their friend, Jimmy Kimmel. They discuss finding humor in tough situations, the things he still wants to accomplish, speaking from your heart, mean tweets, and much more.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This show is sponsored by:
    Maybelline - If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    Lolavie - Get 15% off LolaVie with code MESSY at https://www.lolavie.com/MESSY! #lolaviepod
    ZocDoc - Go to Zocdoc.com/MESSY and download the Zocdoc app for FREE. Then find and book a top-rated doctor today

    • 53 min
    Can I Be Honest?

    Can I Be Honest?

    This week, Christina and Jamie discuss feeling obligated to be strong, the importance of being there for each other, wearing diapers, and much more. They also answer some listener questions.
    Parts of this episode were recorded in 2023.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    Maybelline - If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more.
    Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout visit cionic.com

    Jamie-Lynn Sigler is a paid spokesperson for Novartis. This podcast is independent from Jamie-Lynn Sigler’s collaboration with Novartis.

    • 48 min

Customer Reviews

4.9 out of 5
2.5K Ratings

2.5K Ratings

katrinsjmnjm ,

My Favorite Podcast

I love listening to Jamie Lyn and Christina stories of their struggles and perseverance through the tough times. I have Fibromyalgia and the pain is debilitating. Both these ladies give me hope and inner strength to take on my medical battle with courage and dignity. Looking forward to hearing more podcasts and Godspeed to you both.

Arey888 ,

INSPIRATIONAL, Entertaining,

Amazing podcast by two of my favorite actresses. These women are super talented and intelligent. As a spouse of someone with MS, I can relate to their experiences, thoughts, and relationship issues. Must listen for anyone who has or knows someone who has MS or another misunderstood, stigmatized disease.

Rhondalynn13 ,

Joy and Inspiration in the Mist of the Mess.

I love this podcast. I have been chronically ill with a devastating autoimmune disease affecting the CNS and beyond for a long time and everything these gals share from there own experiences of fighting their wicked disease helps me feel heard and seen. I have related to every topic, struggle, etc. they have been so willingly upfront and graciously vulnerable to personally reveal. In turn, it gives me a sense I am sitting on the bed with them having a heart to heart and hearing myself say, “Me, too. Me, too.” Thank you, ladies, for taking off the masks and pulling back the curtains so people like me have a place to feel understood and not-so-alone. Keep up the great work!

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