Precision Medicine Made Simple Taylor Cu

For this episode, Dr. Stanford, Alyssa Stanford, and Taylor Cu discuss the topic of cancer. Dr. Stanford provides a comprehensive breakdown of cancer cells, stressing the need for genetic and molecular profiling to tailor treatments. They explore the factors that contribute to cancer development, including lifestyle choices and genetic mutations, and emphasize the importance of early detection through screenings and genetic analysis. They also dive into the exciting advancements in early cancer identification, as well as the role of the immune system in fighting cancer cells. 
Timestamps:
[00:08:23] Cell identity, cancer detection, genetic profiling.
[00:15:54] Gene derangement leads to cancer mutations.
[00:23:57] Preventative measures can reduce cancer risk.
[00:31:45] Low uptake in lung cancer screening.
[00:40:17] Early cancer detection crucial for treatment.
[00:48:33] Precision medicine moves beyond one-size-fits-all. Genetic risk and AI for cancer.
[00:56:15] Cancer cells develop resistance, need precision oncology.
[01:04:27] Complexity of cancer, vaccines, and treatments.
[01:13:11] Cancer prevention and precision medicine summary.
Dr. William Stanford MD PHD FACP 
Dr. William Stanford is co-founder of Biography Health. He began his career as a mechanical and aerospace engineer at Texas Instruments in 1982 while also pursuing his interest in aviation as a flight instructor and commercial pilot. In 1991, he pivoted into biomedical science and subsequently completed the combined M.D./Ph.D. physician-scientist training program at the University of California, Los Angeles, in 1998 and an internal medicine residency at UCLA in 2001. He is board-certified in internal medicine and is a Fellow of the American College of Physicians. 
A pioneer in the field of hospital medicine, Dr. Stanford founded and led a 25-physician group of private practice hospitalists at Cedars-Sinai Medical Center in Los Angeles in 2002. After an extensive clinical career as the attending physician for over 100,000 patients, he was elected by his peers at Cedars-Sinai to be clinical chief of general internal medicine, serving in this capacity from 2017 to 2018. Inspired by recent advancements in biomedical science and medicine, Dr. Stanford completed professional certification through Stanford University’s Department of Genetics in 2018, further advancing his role as a true physician-scientist. 
Sponsored by: Biography Health
Biography Health, where healthcare meets personalization. With their DNAbled™ Blueprint, Biography Health empowers you with a health plan based on your unique DNA, aiming to prevent disease and extend your life. Take control of your health journey with a plan as unique as you. Visit BiographyHealth.com and start your personalized healthcare journey today.

For this episode, Dr. Stanford, Alyssa Stanford, and Taylor Cu dive into the complexities of metabolic syndrome, how it can relate to several chronic diseases and discuss the impact of genetics, diet, and exercise on our overall health. We also touch on the importance of precision medicine and continuous glucose monitoring in managing conditions like diabetes and touch on some of the benefits of medications currently out there like Ozempic.
Timestamps:
[00:05:44] Metabolic syndrome increases chronic disease risk.
[00:10:26] Fatty liver disease is a modern problem.
[00:16:27] Processed foods worsen metabolic health, inflammation.
[00:22:40] Eating standing up may worsen insulin resistance.
[00:29:05] High insulin levels lead to diabetes.
[00:35:15] Dexcom for diabetics, Ozempic for symptoms.
[00:40:59] Medications show promise for various benefits.
[00:46:22] Metabolic syndrome is often overlooked.
[00:52:39] Improve health with precision medicine steps.
Dr. William Stanford MD PHD FACP
Dr. William Stanford is co-founder of Biography Health. He began his career as a mechanical and aerospace engineer at Texas Instruments in 1982 while also pursuing his interest in aviation as a flight instructor and commercial pilot. In 1991, he pivoted into biomedical science and subsequently completed the combined M.D./Ph.D. physician-scientist training program at the University of California, Los Angeles, in 1998 and an internal medicine residency at UCLA in 2001. He is board-certified in internal medicine and is a Fellow of the American College of Physicians.
A pioneer in the field of hospital medicine, Dr. Stanford founded and led a 25-physician group of private practice hospitalists at Cedars-Sinai Medical Center in Los Angeles in 2002. After an extensive clinical career as the attending physician for over 100,000 patients, he was elected by his peers at Cedars-Sinai to be clinical chief of general internal medicine, serving in this capacity from 2017 to 2018. Inspired by recent advancements in biomedical science and medicine, Dr. Stanford completed professional certification through Stanford University’s Department of Genetics in 2018, further advancing his role as a true physician-scientist.
Sponsored by: Biography Health
Biography Health, where healthcare meets personalization. With their DNAbled™ Blueprint, Biography Health empowers you with a health plan based on your unique DNA, aiming to prevent disease and extend your life. Take control of your health journey with a plan as unique as you. Visit BiographyHealth.com and start your personalized healthcare journey today.

In this episode, we’re joined by Dr. Stanford and Taylor Cu to explore neurodegenerative diseases such as Alzheimer’s and Parkinson's. It's a particularly personal discussion as Dr. Stanford shares his own genetic risk for Alzheimer’s, linked to the APOE4 gene. Dr. Stanford explains what neurodegenerative diseases are and dives into the specifics of Alzheimer's, including how genetics play a role in its risk. We wrap up the episode by looking at lifestyle changes that could make a significant impact in prevention.
Timestamps:
[00:04:50] Degenerative diseases share commonality in brain shrinkage. Alzheimer's is most common, starts early.
[00:09:24] APOE Epsilon four leads to abnormal function in cholesterol transport, amyloid plaques and tau proteins play a role in Alzheimer's disease progression.
[00:14:03] Alzheimer's disease is complex and mysterious.
[00:18:00] Lifestyle impacts neurodegenerative disease risk.
[00:22:37] Difference between Alzheimer's and general dementia.
[00:27:07] Inflammation bad for heart and brain.
[00:32:23] Genetic testing can predict future health.
[00:37:44] Prevent dementia with lifestyle changes.
[00:43:01] Improve brain health with exercise, socialization.
Dr. William Stanford MD PHD FACP
Dr. William Stanford is co-founder of Biography Health. He began his career as a mechanical and aerospace engineer at Texas Instruments in 1982 while also pursuing his interest in aviation as a flight instructor and commercial pilot. In 1991, he pivoted into biomedical science and subsequently completed the combined M.D./Ph.D. physician-scientist training program at the University of California, Los Angeles, in 1998 and an internal medicine residency at UCLA in 2001. He is board-certified in internal medicine and is a Fellow of the American College of Physicians.

A pioneer in the field of hospital medicine, Dr. Stanford founded and led a 25-physician group of private practice hospitalists at Cedars-Sinai Medical Center in Los Angeles in 2002. After an extensive clinical career as the attending physician for over 100,000 patients, he was elected by his peers at Cedars-Sinai to be clinical chief of general internal medicine, serving in this capacity from 2017 to 2018. Inspired by recent advancements in biomedical science and medicine, Dr. Stanford completed professional certification through Stanford University’s Department of Genetics in 2018, further advancing his role as a true physician-scientist.
Sponsored by: Biography Health
Biography Health, where healthcare meets personalization. With their DNAbled™ Blueprint, Biography Health empowers you with a health plan based on your unique DNA, aiming to prevent disease and extend your life. Take control of your health journey with a plan as unique as you. Visit BiographyHealth.com and start your personalized healthcare journey today.

Dr. Stanford, Alyssa Stanford, and Taylor Cu explore the fascinating world of heart disease and personalized health care. They dive into the complexities of heart disease, discussing the crucial role of genetics, family history, lifestyle, and biochemistry in assessing heart disease risk. Tune in to discover the power of early detection, personalized health plans, and integrative approaches to effectively address heart disease and more.
Timestamps:
[00:05:14] Arterial hardening and narrowing cause issues.
[00:09:11] Early onset heart disease linked to genetics.
[00:13:28] Genetic sequencing can predict heart attack.
[00:18:01] Improve lipid profile with medication, lifestyle.
[00:22:44] Genetic testing predicts future disease risk.
[00:27:35] Genetics and lifestyle impact heart disease.
[00:32:02] Gene editing for liver disease treatment.
[00:36:52] Liver cells have receptors for particles.
[00:42:23] Coronary disease and vascular health summary.
Dr. William Stanford MD PHD FACP
Dr. William Stanford is co-founder of Biography Health. He began his career as a mechanical and aerospace engineer at Texas Instruments in 1982 while also pursuing his interest in aviation as a flight instructor and commercial pilot. In 1991, he pivoted into biomedical science and subsequently completed the combined M.D./Ph.D. physician-scientist training program at the University of California, Los Angeles, in 1998 and an internal medicine residency at UCLA in 2001. He is board-certified in internal medicine and is a Fellow of the American College of Physicians.

A pioneer in the field of hospital medicine, Dr. Stanford founded and led a 25-physician group of private practice hospitalists at Cedars-Sinai Medical Center in Los Angeles in 2002. After an extensive clinical career as the attending physician for over 100,000 patients, he was elected by his peers at Cedars-Sinai to be clinical chief of general internal medicine, serving in this capacity from 2017 to 2018. Inspired by recent advancements in biomedical science and medicine, Dr. Stanford completed professional certification through Stanford University’s Department of Genetics in 2018, further advancing his role as a true physician-scientist.
Sponsored by: Biography Health
Biography Health, where healthcare meets personalization. With their DNAbled™ Blueprint, Biography Health empowers you with a health plan based on your unique DNA, aiming to prevent disease and extend your life. Take control of your health journey with a plan as unique as you. Visit BiographyHealth.com and start your personalized healthcare journey today.