37 episodes

Known for its synergistic approach to biomedical science, the Intramural Research Program (IRP) is the internal research program of the National Institutes of Health (NIH). With 1,100 Principal Investigators and more than 4,000 Postdoctoral Fellows conducting basic, translational, and clinical research, the IRP is the largest biomedical research institution on earth. Its mission is science in pursuit of fundamental knowledge about living systems and the application of that knowledge to extend healthy life and reduce illness and disability throughout the world. In the IRP's new podcast, Speaking of Science, you will meet many of the federal researchers working to change lives by advancing all aspects of biomedicine.

Speaking of Science The Intramural Research Program of the National Institutes of Health (NIH)

    • Health & Fitness
    • 5.0 • 37 Ratings

Known for its synergistic approach to biomedical science, the Intramural Research Program (IRP) is the internal research program of the National Institutes of Health (NIH). With 1,100 Principal Investigators and more than 4,000 Postdoctoral Fellows conducting basic, translational, and clinical research, the IRP is the largest biomedical research institution on earth. Its mission is science in pursuit of fundamental knowledge about living systems and the application of that knowledge to extend healthy life and reduce illness and disability throughout the world. In the IRP's new podcast, Speaking of Science, you will meet many of the federal researchers working to change lives by advancing all aspects of biomedicine.

    Dr. Michael Ombrello — The Rare Case of Beverly Gage

    Dr. Michael Ombrello — The Rare Case of Beverly Gage

    Beverly Gage came to the NIH with a condition that had never been observed before. A mysterious genetic mutation that caused her chronic joint pain and inflammation led her to Dr. Michael Ombrello, an expert in rare inflammatory diseases at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). Where their paths cross shows us the current challenges of diagnosing, treating, and living with a disorder that is new to science.

    • 28 min
    Dr. Sadhana Jackson — Breaking Through the Blood-Brain Barrier

    Dr. Sadhana Jackson — Breaking Through the Blood-Brain Barrier

    The blood-brain barrier keeps bad actors like toxins, viruses, and bacteria from entering the brain. But in the case of brain cancer when the danger is already inside, the blood-brain barrier can work against a person’s health by shutting out the medications meant to eliminate the threat. Dr. Sadhana Jackson from the National Institute of Neurological Disorders and Stroke (NINDS) works to figure out ways to selectively get cancer treatments through the blood-brain barrier to treat patients with certain types of brain tumors known as gliomas.
    Learn more about Dr. Jackson work at https://irp.nih.gov/pi/sadhana-jackson.

    • 25 min
    Dr. Meredith Shiels — Health in Numbers

    Dr. Meredith Shiels — Health in Numbers

    Epidemiologists are the watchful guardians of public health. They collect and analyze data to track the status quo. When there are deviations, they crunch the numbers to understand who is getting sick, where, how, and why. Dr. Meredith Shiels is an epidemiologist and senior investigator at the National Cancer Institute (NCI) studying cancer mortality rates to discern what populations might be at higher risk, figure out ways to mitigate those risks, and evaluate whether those measures are working.  
    Learn more about Dr. Shiels’s research at  https://irp.nih.gov/pi/meredith-shiels.

    • 29 min
    Dr. Veronica Alvarez and Dr. Bruno Averbeck — On the Pulse of Compulsive Behaviors

    Dr. Veronica Alvarez and Dr. Bruno Averbeck — On the Pulse of Compulsive Behaviors

    Despite negative consequences and the desire to stop, millions of people with compulsive behaviors can’t break the self-destructive cycles that disrupt their daily lives. Dr. Veronica Alvarez and Dr. Bruno Averbeck from the National Institute of Mental Health run the Center on Compulsive Behaviors (CCB) which brings together NIH scientists to understand what drives these repetitive and often detrimental behaviors. The CCB strives to decipher the neural circuitry that leads to compulsive behaviors in hopes of improving treatments and designing new interventions.
    Learn more about the CCB at https://research.ninds.nih.gov/researchers/center-compulsive-behaviors-ccb.

    • 32 min
    Dr. John Hanover — The Bittersweet Study of Glycobiology

    Dr. John Hanover — The Bittersweet Study of Glycobiology

    Sugars, also referred to as carbohydrates, aren’t just substances we add to make coffee taste less bitter or food sweeter; they are an entire class of molecules necessary for life. The study of these carbohydrates is called glycobiology. Dr. John Hanover is a glycobiologist and the chief of the laboratory of cell and molecular biology at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). His work is advancing scientists’ understanding of the sugar structures responsible for rare diseases and genetic transgenerational inheritance.

    • 23 min
    Dr. Sharon Milgram — Making the Most of the Trainee Experience

    Dr. Sharon Milgram — Making the Most of the Trainee Experience

    None of the groundbreaking research taking place in the IRP would be possible with the hard work and dedication of trainees. While they work to support the NIH’s mission to turn discovery into health, the Office of Intramural Training and Education (OITE) works to supports trainees in their professional pursuits. Dr. Sharon Milgram is the director of OITE and a strong proponent that good training begets good science. In this episode, she talks about the many ways OITE supports students and fellows so that they can achieve their best work and make the most of their experience in the IRP.

    • 30 min

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