The Life Scientific

The Life Scientific

Professor Jim Al-Khalili talks to leading scientists about their life and work, finding out what inspires and motivates them and asking what their discoveries might do for us in the future

  1. 8 HR AGO

    Jonathan Shepherd on a career as a crime-fighting surgeon

    Surgeons often have to deal with the consequences of violent attacks - becoming all too familiar with patterns of public violence, and peaks around weekends, alcohol-infused events and occasions that bring together groups with conflicting ideals. Professor Jonathan Shepherd not only recognised the link between public violence and emergency hospital admissions, he actually did something about it. As a senior lecturer in Oral and Maxillofacial Surgery in the early 1980s, Jonathan started looking into this trend - and his research revealed that most violent assaults resulting in emergency hospital treatment are not reported to police. As a result, he devised the ‘Cardiff Model for Violence Prevention’: a programme where hospitals share data about admissions relating to violent attacks with local authorities. He also went on to study various aspects of violent assault and deliver evidence-based solutions - from alcohol restrictions in hotspots, to less breakable beer glasses in pubs. The impacts have been significant, delivering reductions in hospital admissions and in violent attacks recorded by police; not only in Cardiff, but in cities around the world where the model is used. Today, as an Emeritus Professor of Oral and Maxillofacial Surgery at Cardiff University - where he’s also Director of their Crime, Security and Intelligence Innovation Institute - Jonathan continues to bring together the medical sector with local authorities, finding practical ways to make cities and their residents safer. But his career, straddling the worlds of practise, science and policy, is an unusual one; here he talks to Professor Jim Al-Khalili about what drove him to make a difference. Presentedby Jim Al-Khalili Produced by Lucy Taylor

    29 min
  2. 18 MAR

    Sir Magdi Yacoub on pioneering heart transplant surgery

    What does it take to earn the nickname, ‘The Leonardo da Vinci of heart surgery’? That's the moniker given to today's guest - a man who pioneered high-profile and often controversial procedures, but also helped drive huge medical progress; carrying out around 2,000 heart transplants and 400 dual heart-lung transplants during his 60-year career. Sir Magdi Yacoub is Emeritus Professor of Cardiothoracic Surgery at Imperial College London, and Director of Research at Harefield Hospital’s Magdi Yacoub Institute. Inspired by a surgeon father and impacted by the tragic early death of his aunt from a heart condition, his medical career includes various surgical firsts alongside numerous research projects, to further our understanding of and ability to treat heart disease. He headed up the teams that discovered it is possible to reverse heart failure, and that successfully grew part of a human heart valve from stem cells for the first time. But it hasn't always been plain sailing. At times, his work – such as early, unsuccessful transplant attempts, or using a baboon as a life-support system for a baby – attracted serious public criticism. Speaking to Professor Jim Al-Khalili, Sir Magdi reflects on the highs and lows of his cardio career, and offers his advice to the next generation of surgeons and researchers hoping to make their mark in heart medicine. Presented by Jim Al-Khalili Produced by Lucy Taylor

    29 min
  3. 17/09/2024

    Rosalie David on the science of Egyptian mummies

    Rosalie David is a pioneer in the study of ancient Egypt. In the early 1970s, she launched a unique project to study Egyptian mummified bodies using the techniques of modern medicine. Back then, the vast majority of Egyptologists regarded mummies as unimportant sources of information about life in ancient Egypt. Instead they focussed on interpreting hieroglyphic inscriptions, the written record in papyrus documents and archaeological remains and artefacts. Rosalie David proved that the traditionalists were quite wrong. Professor David’s mummy research started at the Manchester Museum when she began to collaborate with radiologists at the nearby Manchester Royal Infirmary, taking the museum’s mummies for x-rays at the hospital. Her multi-disciplinary team later moved to a dedicated institute at the University of Manchester, the KNH Centre for Biomedical Egyptology. Over the decades, the team there has made remarkable discoveries about disease and medicine in ancient Egyptian society, providing a new perspective on the history of medicine and giving extraordinary insights into the lives of individuals all those years ago. Rosalie tells Jim Al-Khalili about her journey from classics and ancient history to biomedicine, including some of her adventures in Egypt in the 1960s. She talks about some of her most significant research projects, and the 21st Century forensic detective work on the mummy of a young woman which revealed a gruesome murder 3,000 years ago... Presented by Jim Al-Khalili Produced by Andrew Luck-Baker

    28 min

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    Professor Jim Al-Khalili talks to leading scientists about their life and work, finding out what inspires and motivates them and asking what their discoveries might do for us in the future

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