62 episodes

Rheumatology is an incredibly fast-moving and exciting field of medicine that can be difficult to keep up with. This podcast provides busy clinicians with quick updates in the field of autoimmunity, with emphasis on new medications, treatment guidelines and explorations into the pathophysiology of diseases. The show will also feature historical perspectives in the field of rheumatology, as well as fascinating case presentations of medical mysteries complete with discussions from experts in the field.

Healio Rheuminations Adam J. Brown, MD

    • Health & Fitness
    • 4.9 • 82 Ratings

Rheumatology is an incredibly fast-moving and exciting field of medicine that can be difficult to keep up with. This podcast provides busy clinicians with quick updates in the field of autoimmunity, with emphasis on new medications, treatment guidelines and explorations into the pathophysiology of diseases. The show will also feature historical perspectives in the field of rheumatology, as well as fascinating case presentations of medical mysteries complete with discussions from experts in the field.

    A Cat in Wolves' Clothing, Part 2: The History of Bartonella

    A Cat in Wolves' Clothing, Part 2: The History of Bartonella

    Is this episode clinically relevant? No. Is it important? I think so! The story of Bartonella features a cast of characters, including a medical student who died trying to understand the disease, as well as some scientists with some less than ethical experiments. Enjoy!
    Intro :01 Welcome to another exciting episode of Rheuminations :11 About today’s episode 1:12 More discussion of Bartonella quintana 2:52 How did we figure out the lice were actually the problem? 7:32 When do we figure out what this infection organism is? 11:51 A quick refresher of Koch’s postulates 12:58 How did they get the volunteers to do this? 13:33 The story of how Bartonella got its name 17:00 What is Bartonella bacilliformis? 17:38 Who is Richard Strong? 26:29 How do we finally prove that Carrion’s disease is what Carrion had proven? 28:25 About Bartonella henselae 32:21 Recapping the episode 36:39 Thanks for listening 37:24 We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum.
    Disclosure: Brown reports no relevant financial disclosures.
    References: 
    Anstead GM. Lancet Infect Dis. 2016;16:e164–172.
    Salinas-Flores D.  Revista de la Facultad de Medicina, Universidad Nacional de Colombia. 2016;64:517.
    Schultz MG. Am J Trop Med Hyg. 1968;17:503-515.
    Vinson JW, et al. Am J Trop Med Hyg. 1969;18:713-22.

    • 37 min
    A Cat in Wolves’ Clothing: Bartonella and the Rheumatologist

    A Cat in Wolves’ Clothing: Bartonella and the Rheumatologist

    Bartonella is an important mimic of a variety of autoimmune diseases, and it can be subtle. This episode tackles the ways in which this strange organism can present to a rheumatologist.
    Brought to you by Genentech
    Intro :01 Today’s episode :15 Overview of Bartonella 1:57 Inspiration for this episode 4:17 Bartonella, what are you? 7:24 About Bartonella quintana 12:32 Take-away so far 16:07 Core symptoms and rheumatologic aspects 17:15 About serologies 24:51 Key takeaways from this episode 28:09 Check out Rheum + Boards on Healio at com/rheumandboards 28:31 Disclosure: Brown reports no relevant financial disclosures.
    We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum and be sure to check out Rheum + Boards – your destination for rheumatology education and quizzes!
    References:
    Aslangul E, et al. J Rheumatol. 2014;doi:10.3899/jrheum.130150.
    Beydon M, et al. Rheumatology (Oxford). 2021;doi:10.1093/rheumatology/keab691.
    Im JH, et al. Vector Borne Zoonotic Dis. 2018;18:291-296.
    Jacobs RF, Schutze GE. Clin Infect Dis. 1998;26:80-84.
    Maman E, et al. Clin Infect Dis. 2007;45:1535-1540.
    Raybould JE, et al. Infect Dis Clin Pract (Baltimore). 2016;24:254-260.
    Zangwill KM, et al. N Engl J Med. 1993;329:8-13.

    • 29 min
    Sponsored Episode: Counseling Patients on Cardiovascular Risk and Rheumatoid Arthritis

    Sponsored Episode: Counseling Patients on Cardiovascular Risk and Rheumatoid Arthritis

    This podcast series is sponsored by Vectra®. Discussion does not constitute or imply endorsement of the product.
    In this episode, Adam J. Brown, MD, and Leonard H. Calabrese, DO, discuss how rheumatologists can evaluate their patients for cardiovascular risk, how to counsel patients about risk factors, and the role of general wellness and wellbeing in the management of rheumatoid arthritis.
    Intro 0:11 Today’s episode 0:32 Intro of Dr. Leonard H. Calabrese 0:48 How do you discuss cardiovascular risk with RA patients? 2:07 When do you bring up the topic of cardiovascular risk with a patient? 5:18 What lifestyle changes do you discuss with RA patients concerned about cardiovascular risk? 7:36 How do you address fatigue when discussing lifestyle adjustments with patients? 12:35 When fatigue lingers despite effective therapeutics 15:49 The importance of adopting wellness behaviors 18:00 Empowering patients to make lifestyle modifications 21:03 Thanks for listening 23:04

    • 23 min
    Sponsored Episode: Biomarkers in Cardiovascular Risk and Rheumatoid Arthritis

    Sponsored Episode: Biomarkers in Cardiovascular Risk and Rheumatoid Arthritis

    This podcast series is sponsored by Vectra®. Discussion does not constitute or imply endorsement of the product.
    In this episode, Adam J. Brown, MD, and Jeffrey Curtis, MD, discuss the multiple biomarkers associated with cardiovascular risk in rheumatoid arthritis, as well as the reasoning behind the development of a biomarker-based cardiovascular risk model. 
    Intro :10 Intro of Dr. Jeffrey Curtis :22 Today’s episode :56 Tell us about your background and how you got to where you are? 3:29 What do rheumatologists need to be using other than existing score-based systems to predict cardiovascular risk? 5:06 Are traditional risk factor calculators helpful? What are they missing? 6:32 Considering disease level/activity when looking at overall cardiovascular risk 8:07 A high-level look at multiple biomarker-based tests 9:38 How were the 12 individual biomarkers originally selected? 11:42 How do you go about implementing the test? How do you get patients? 17:23 How is the test ordered and how do you walk a patient through it? 19:48 How is the timeframe based? 21:56 When are physicians ordering this test? 23:46 The use of biomarker information in educating patients about additional risk factors 26:36 What’s going into the score generated by test? 27:36 How to use the resulting score in conversations with patients 28:19 Additional work and responsibility for rheumatologists as a result of this test being available 30:16 Thanks for listening 33:17 Additional work and responsibility for rheumatologists as a result of this test being available 31:45 Thanks for listening 34:50

    • 33 min
    Sponsored Episode: A Historical Look at Cardiovascular Risk in Rheumatoid Arthritis

    Sponsored Episode: A Historical Look at Cardiovascular Risk in Rheumatoid Arthritis

    This podcast series is sponsored by Vectra®. Discussion does not constitute or imply endorsement of the product.
    In this episode, Adam J. Brown, MD, and Jon Giles, MD, explore the history of cardiovascular risk in rheumatoid arthritis from the 1950s onward, including the emergence of data surrounding inflammation and cardiovascular disease, as well as the need for therapeutics that go beyond simply treating joint pain.
    Intro :11 Intro of Dr. Jon Giles :22 Today’s episode 1:36 How did you become interested in cardiovascular disease in rheumatology? 2:18 When did cardiovascular risk become part of the discussion about RA? 4:33 How to follow patients over time and develop a better sense of cardiovascular risk through studies. 7:23 Are there unique cardiovascular risk factors among RA patients? 10:19 CRP levels as predictive of cardiovascular events 12:09 The biology behind cytokines associated with cardiovascular risk 14:22 Are current interventions and therapeutics making a difference? 16:27 General awareness among patients and physicians of cardiovascular disease and RA 18:29 Roles and responsibilities in cardiovascular risk management 21:15 How do we screen for cardiovascular risk beyond lipid panels? 22:27 Where is the field of cardiovascular risk and RA going? 24:01 Steroids, NSAID’s, and cardiovascular risk 25:43 Episode wrap up 27:04 Thanks for listening 27:49

    • 27 min
    Paget's and the Rheumatologist: Why Haven't I Seen This Yet?

    Paget's and the Rheumatologist: Why Haven't I Seen This Yet?

    What is Paget’s? Why is it declining across much of the globe? Find out, plus hear an interview with the head of the center for osteoporosis and metabolic bone disease at Cleveland Clinic, Chad Deal, MD.
    Brought to you by GSK.
    Intro :11 Today’s episode :27 What is Paget’s? 1:07 The history of Paget’s 5:35 How often is this symptomatic? 9:30 The epidemiology of Paget’s 13:22 The data on viruses and Paget’s disease 21:08 An interview with Dr. Chad Deal25:09 The numbers are showing a decline in Paget’s disease, are you seeing that? 26:03 Identifying Paget’s disease … who’s picking this up? 27:01 Can you walk us through those studies again? 27:58 Can you tell us a little bit about hypervascularity found in these patients? 30:32 Can you walk us through the history of how the treatments have changed? 31:37 Paget’s kind of just doesn’t go anywhere … is that what you’ve seen in your practice? 35:05 What if the patient has poor or borderline kidney function? Do they have other options? 37:07 Have you seen familial cases? Are people more prone to get it if someone in the family has it? 38:32 A discussion on osteosarcoma 39:55 Dr. Deal, thank you so much for your time and your knowledge about metabolic bone 42:46 Episode summary 42:52 I hope you learned something and thanks for listening! 44:47 Disclosure: Brown reports no relevant financial disclosures. Healio was unable to confirm relevant financial disclosures for Deal at the time of publication.
    We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum
    References:
    Cundy T. Metabolism. 2018;80:5-14.
    Haddaway MJ, et al. Br J Radiol. 2007;80:523-526.
    Poór G, et al. J Bone Miner Res. 2006;21:1545-1549.
    Renier JC, Audran M. Rev Rhum Engl Ed. 1997;64:35-43.
    Shaw B, et al. Proc Natl Acad Sci USA. 2019;10463-10472. 
    Singer FR. Nat Rev Endocrinol. 2015;11:662-671.
    Wermers RA, et al. J Bone Miner Res. 2008​;23:819-825.
    Music by Lesfm from Pixabay.

    • 45 min

Customer Reviews

4.9 out of 5
82 Ratings

82 Ratings

CJE2022 ,

Great podcast

Dr. Brown has a delightful charm that always keeps me coming back to this channel. His humor and genuineness are top notch, and the content is very engaging.

AmyFro ,

Binge listening to this show

I love this podcast. Great story telling. Dr. Brown is funny, has a passion for learning and educating, combined with solid understanding of the research and the clinical practice in this field. He manages to translate the research in such a clear way that I don't get lost in the acronyms and can easily follow the concepts. Great communicator--thanks for breaking it down. I wish you were my rheumatologist!

Cebooth1 ,

Thank you

Thanks for this informative and entertaining podcast!
-Ohio private practice/solo Rheumie

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