Discussions about the science of nutrition, dietetics and health. The podcast that educates through nuanced conversations, exploring evidence and cultivating critical thinking. Hosted by Danny Lennon.
#415: Prof. Bruce Neal – Can Salt Substitutes Reduce Cardiac Events & Death?
Bruce Neal is Executive Director at The George Institute for Global Health Australia; and Professor of Medicine, UNSW Sydney.
Prof Neal is a UK-trained physician who has 25 years’ experience in clinical, epidemiological, and public health research with a focus on heart disease, stroke and diabetes. Bruce has a longstanding interest in high blood pressure and diabetes and the potential for both clinical interventions and changes in the food supply to deliver health gains. His work has been characterised by its focus on collaboration, quantitation, translation and impact.
He holds professorial appointments at UNSW Sydney, Imperial College London, and an honorary appointment at the University of Sydney. He has published some 450 scientific papers and since 2016 has been identified by Thomson Reuters as one of ‘The World’s Most Influential Scientific Minds’, an acknowledgement provided to just a few thousand researchers across all disciplines, worldwide.
He has particular expertise in the conduct of large-scale clinical trials addressing cardiovascular disease but has also done a significant body of work addressing food policy issues related to sugars, fats, portion size and food labelling.
Find the show notes at sigmanutrition.com/episode415/
#414: Will Machine Learning Overtake Traditional Nutrition Research Methods?
In this episode, the Sigma team discuss the claim that machine learning and data science may overtake traditional research methods in nutrition. They discuss how machine learning could solve some current limitations of traditional methods, studies on its use so far, potential applications in future trials, and potential limitations or problems with the increased use of data science (including ethical and societal concerns). They also ponder on how tech is currently being used (and abused) in relation to personalised nutrition, tech products, continuous glucose monitoring use, among other things.
#413: Anthony Fardet, PhD – Nutritional Reductionism, the Food Matrix & Impact of Processing
" data-userid="424351203778215936" data-orgid= "425311536639447040">Anthony Fardet, PhD is a nutrition science researcher in the Human Nutrition Unit at Université Clermont Auvergne, France. His work has focused on a number of related areas; the consequences of the reductionist and holistic approaches applied to nutrition research, the relevance of a new classification of foods based on their degree of processing, and the role of the complex structure of the food in its health potential ("matrix effect").
You can find the show notes to this episode at sigmanutrition.com/episode413/
#412: Eirini Dimidi, PhD – Diet, Chronic Constipation and the Gut
" data-userid="424351203778215936" data-orgid= "425311536639447040">Dr. Eirini Dimidi of King’s College London discusses the research on diet in chronic constipation and functional bowel disorders. Dr. Dimidi is a Lecturer in Nutritional Sciences and a Registered Dietitian. In 2016, she was appointed as a Research Associate at King’s College London, where she undertook several research projects on the impact of nutritional interventions in gut function and dysfunction.
" data-userid="424351203778215936" data-orgid= "425311536639447040">Dr. Dimidi is undertaking research on nutrition-based interventions, including fibre, plant foods, prebiotics, probiotics, and the low FODMAP diet, in gastrointestinal health. Her primary focus is to advance the understanding of the impact of dietary therapies in functional bowel disorders, including chronic constipation and irritable bowel syndrome.
" data-userid="424351203778215936" data-orgid= "425311536639447040">You can find the show notes to this episode at sigmanutrition.com/episode412/
#411: Bone Health & Nutrition
In this episode Alan and Danny discuss the role of nutrition in bone health. They cover the importance of bone health, bone disorders such as osteoporosis, how nutrients play a role in bone remodelling, and the evidence of dietary and supplementation trials on bone health outcomes.
You can find the show notes, with links to all the reference studies, at sigmanutrition.com/episode411/
#410: Q&A: Sodium, Protein, Quackery Tactics & More!
In this episode Alan and Danny answer a variety of questions sent in from listeners.
[1:10] Gabriel - Is there any benefit to including SFAs and cholesterol in low quantities in our diets for healthspan?
[10:42] Luis Arrondo - Can I do 3 rather than 4 meals or more for protein absorption by increasing grams of protein? How many grams of protein can be absorbed at one sitting. Does taking in protein at night help more absorption of protein? If so, something slower, like milk over whey? Last, how much protein per kilo of weight to gain muscle via weightlifing?
[19:34] Heather Smith - Please could you go into the sodium needs of those with hypotension. Your podcast about normotension and hypertension was excellent, as was the section relating to athletes. I’d love to hear your thoughts on the sodium needs of a hypotensive person. Thank you!
[27:00] Judith Williams - I would find it really helpful if you could summarise what the evidence shows are the key dietary changes for long term weight loss.
[36:41] Dale Grant - Great podcast and episode as normal especially the quack asylum (big fan of this segment). Having listened to a few of these extreme people (quacks) on various platforms, I’ve noticed they also employ an aggressive falsify my opponents position tactic. Its almost as if they are aware of Karl Poppers falsification principle, but have misinterpreted it as falsify my "opponents" position instead of my own. Aside from the fact they falsely view the person they are having a debate with as their “opponent”, they miss the point that they should be trying to find evidence to falsify their own position, and thus get closer to a capital T Truth. On the other hand as Alan pointed out with Assem Mahlhotra, this may just be a reluctance to acknowledge evidence for other reasons (narcissism, us vs Them narrative, etc). Nowhere was this more apparent than when James Wilks (host of mass propaganda film game changers), sought to aggressively debate Chris Kresser on the Joe Rogan Podcast. Considering Wilks is a former cage fighter this wasn’t surprising. Unfortunately, this aggressive tactic does lead some people to conclude that Wilks has “won” the argument, because he has “won” the debate. Similar to most modern debates, it seems like you don’t have to win the debate intellectually with reason. Instead you just have to make it seem as if your more competent than your opponent. Do you agree these extreme people employ this tactic? and how do you think we could improve “scientific” debates (note inverted commas) in the public domain in the future?
[46:40] Dimitri - Should fruit consumption be moderated because of the sugar content? For example, a fig has 8g of sugar, can I eat 5-10 in one sitting or would that be detrimental to health?
[51:26] Rebecca Toutant - What is the evidence / practice behind integrative and functional nutrition?
[56:06] Duncan Clarke - This will be a strange question for you but I'll send it anyway. How could a cyclist specifically lose upper body muscle mass? For example a fit healthy athlete from another sport takes up cycling and they now have more arm/shoulder muscle than needed. The goal being to maximize the power to weight ratio for climbing.
[60:15] Gabriel - Do you foresee any public health issues related to the increasing popularity of plant based diets, where less careful individuals may face issues consuming certain nutrients harder to get from a plant based diet, such as preformed Vitamin A, choline, iron, protein etc?
[72:03] Ward Stanford - After re-listening to your podcast on weight maintenance over time I was wondering what information exists on the idea of establishing new body fat set points. It seems like merely existing at a lower bf% for a period of time may not be enough, but what are your thoughts on one's ability to truly create a lower set point where it becomes easier to maintain a lower body fat, and how long would you
Best podcast for the latest nutrition research.
This is the only podcast to get the most and latest nutrition education for everyone. It does focus on athletic performance based nutrition but pertinent information for everyone interested in the evidence based nutrition practices. Danny is so knowledgeable and prepared when he interviews his guests. Often times the guests comment on his great questions and how knowledgeable he is on the topics being covered. Highly, highly recommend this podcast.
I really enjoy listening to the shows. I’ve logged in plenty of bike riding miles with Danny learning some really interesting things. Not being having a nutrition background I’m addicted to the next show! Thank you.
Thank you for the quack asylum!
I appreciate that this podcast explores the middle ground rather than exploit the black and white thinking around nutrition science! I also appreciate the quack asylum. As a clinical dietitian working in Cleveland Ohio, I personally experience the harm of the dietary advice influenced by Dr. mark Hyman, Dr. Caldwell Esselstyn, and Dr. Michael Roizen. Nutrition is a fluid changing state based on many factors, and not a one size fits all approach. Keep up the good work!