Chemist Confessions Chemist Confessions Inc.

In this episode, we’re continuing our Vitamin C series and are focusing on actives layering. Most of the questions we get are on whether or not you can layer certain actives with the very fussy ascorbic acid. We first review guidelines on the concept of layering, go through any evidence on ascorbic acid layering combinations, and finally discuss which pairings you should and shouldn’t worry about.

We’ve dedicated many episodes to Vitamin C, but there’s still more to cover! Recently, there have been a lot of Vitamin C launches and they are specifically for tackling hyperpigmentation. What makes this arena slightly confusing is that many of these products use Vitamin C derivatives. But, how helpful is Vitamin C in helping to tackle this very stubborn skin concern? And which Vitamin C molecule is best? We discuss all this and more. It’s time to go down the rabbit hole again!

We’ve encountered many skincare users who have discovered that the Vitamin C realm is just not their cup of tea and neither is it for their skin. Enter resveratrol! We discuss what resveratrol is, its antioxidant capabilities, and why despite the amount of data, we consider this a solid option as a non-Vitamin C antioxidant replacement. You’ve been warned, we get nerdy here, but lets go down the rabbit hole shall we?

There’s a lot of rice-based ingredients and rice-adjacent ingredients in skincare. They can span from functional ingredients such as waxes and thickeners to exotic actives like the very famous Pitera. Amongst all of these ingredients, there’s one isolated active compound that we believe deserves some attention and that is kojic acid. This ingredient is a byproduct of the sake fermentation process and happens to have some solid data as a hyperpigmentation-fighting active. So let’s dive in!

Centella Asiatica (aka cica) has continued to reign as a trendy plant-based active. For good reason! With origins as a wound healing ingredient, the research behind centella asiatica as a skincare ingredient has really grown. We go through the research update and talk about its benefits as a skin soother and possible anti-aging ingredient. Finally, we walk through how to shop for centella asiatica and ultimately how to hunt for the good stuff: madecassoside & asiaticoside.

In the world of AHAs, mandelic acid feels like that forgotten child. We always talk about the golden child, glycolic acid, as well as the more gentle exfoliator, lactic acid. So when would a person need mandelic acid in their life? We go through the data and discuss who it’s good for, how much you should be using, and how to shop for this unique AHA.