Extend Podcast with Darshan Shah, MD

Darshan Shah, MD
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Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan. Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results. That's why this podcast is all about cutting through the noise on how to turn back the aging clock. I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health. Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.

  1. 1 DAY AGO

    112. Josh Clemente: Why Energy Crashes Keep Happening and How to Stop Them

    What if the future of medicine isn't about diagnosing disease, but preventing it entirely? For decades, our healthcare system has only reacted once things go wrong. We measure when there are symptoms. We intervene when there is a crisis. But what if we could see the shift before it becomes an illness? In this episode of EXTEND, I'm joined by Josh Clemente, founder of Levels and former SpaceX engineer, to explore how continuous health monitoring is about to change human health at scale. Josh shares how engineering principles—not traditional medicine—first revealed the hidden metabolic patterns that were draining his energy, affecting his cognition, and pushing him toward disease long before any lab test reflected it. We discuss why continuous glucose monitoring is only the first step in this revolution, how data empowers individuals instead of the healthcare system, and why the next era of health will be defined by observability—real-time insight that lets you adjust, course-correct, and optimize your biology every single day. Josh Clemente is the co-founder of Levels, a metabolic health platform bringing continuous glucose monitoring and real-time lifestyle coaching to the mainstream. Previously, he led life support systems engineering at SpaceX, where he developed safety technology for astronauts aboard the Crew Dragon spacecraft. What's Discussed: (00:00) Why You Should Own Your Health Data — Not Your Doctor (05:50) The Tech That's About to Replace Annual Checkups (17:47) The Medical System Won't Fix Chronic Disease — You Will (26:02) AI + Biology: The Turning Point We've Been Waiting For (35:15) Learning to "Read" Your Body in Real Time (45:54) How Small Daily Inputs Create (or Reverse) Disease (57:05) What's Coming Next in Wearable Health Tech (01:06:57) Continuous Monitoring: The Future of Metabolic Health (01:13:57) Metabolic Health = Energy. And Energy = Life. (01:27:11) Final Takeaways: Empowerment, Data, and Ownership Thank You for Our Sponsors:  NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Josh Clemente:  Instagram: @levels Instagram: @josh.f.clemente  Website: https://www.levels.com/

    1h 29m

  2. 3 DAYS AGO

    111. Dr. Amir Vookshoor: Neurosurgeon Secrets For Bulletproof Brain Health

    What if the real key to longevity has nothing to do with your workouts or supplements, but with how well your brain is wired to adapt, repair, and thrive? In this episode of EXTEND, I sit down with Dr. Amir Vookshoor, a board-certified neurosurgeon and founder of NeuroVella Brain Spa, to explore how modern neuroscience and biohacking are merging to shape the future of brain health. We dive into how trauma, inflammation, and stress rewire the nervous system and how to reset it. From neurofeedback and TMS to breathwork, sleep, and emerging tools like plasmapheresis and light-based neuromodulation, this conversation reveals the most powerful, science-backed ways to reprogram the brain for focus, resilience, and longevity. Dr. Amir Vookshoor is a pioneering neurosurgeon integrating modern neuroscience with holistic medicine to help patients achieve optimal brain function. His work bridges surgery, neuroplasticity, and mind-body science to unlock new pathways for healing and human potential. What's Discussed: (00:00) From Neurosurgery to the Future of Brain Health (10:42) How Stress and Trauma Rewire the Nervous System (19:58) Neurofeedback, Brain States, and Consciousness (31:25) Advanced Imaging and Early Alzheimer's Prevention (40:16) Plasmapheresis and the Science of Brain Renewal (50:27) Breathwork, Sleep, and the Brain-Body Connection   Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about : Instagram: @drvokshoor Website:  NEUROSURGERY & SPINE GROUP

    1h 15m

  3. 6 NOV

    110. Dr. Josh Axe: The Hidden Connection Between Faith, Emotion, and Aging

    What if the key to living longer and feeling younger has been hidden in ancient medicine all along? Long before supplements, peptides, or wearables, healing was about restoring balance through food, movement, belief, and nature. Today, those same principles are being shown by modern science to protect your cells, extend your healthspan, and reverse root causes of disease. In this episode of EXTEND, I'm joined by Dr. Josh Axe and we explore how ancient healing systems like Ayurveda and Traditional Chinese Medicine intersect with today's most advanced longevity research. We dive into the biology of faith and mindset, how chronic stress and emotion impact gene expression, and the connection between gut health, inflammation, and aging. We also discuss how to bridge natural and modern medicine, the surprising role of peptides and stem cells in regeneration, and why true longevity begins with the everyday habits you practice, not just the protocols you chase. Dr. Josh Axe, DC, DNM, CNS, is a doctor of chiropractic and natural medicine, a clinical nutritionist, and the co-founder of Ancient Nutrition. He is also the host of the podcast The Dr. Josh Axe Show and the bestselling author of Ancient Remedies and The Biblical Diet. We Also Discuss: (00:04) Traditional vs. Western medicine and where real healing happens (08:51) Ancient nutrition and the science of longevity (14:31) The emotional biology of healing in Eastern medicine (25:55) Biblical health codes and the roots of longevity (38:06) Mold toxicity, early signs, triggers, and recovery (52:26) Illness, purpose, and the path to healing (01:12:38) Regenerative therapies using peptides and stem cells (01:27:59) The future of wellness through ancient wisdom and modern science Thank You to Our Sponsors: Timeline: Go to timeline.com/drshah to get 20% off your order. Function Health: Learn more and join using functionhealth.com/drshah. The first 1000 get a $100 credit toward their membership. Visit www.functionhealth.com/drshah or use gift code DRSHAH100 at sign-up to own your health.  Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Dr. Josh Axe: Website: www.draxe.com Instagram:@drjoshaxe YouTube: www.youtube.com/@DrJoshAxe

    1h 31m

  4. 4 NOV

    109. Dr. Gladys McGarey: What 103 Years of Life Can Teach Us About Longevity

    What if the real secret to longevity isn't found in science alone, but in how we choose to live, love, and connect every day? In this special posthumous episode of EXTEND, I revisit one of the most meaningful conversations I've ever had — with Dr. Gladys McGarey, the 103-year-old physician known as the Mother of Holistic Medicine and author of The Well-Lived Life. Before her passing, Dr. McGarey shared a century's worth of wisdom on what truly heals us, from the inside out. We talk about how she helped create the holistic medicine movement, the deeper meaning behind her "Five L's" — love, life, laughter, labor, and listening — and how energy, purpose, and community shape both health and happiness. She also shares powerful stories from her early life in India, her encounter with Gandhi, and how compassion became the foundation of her medical practice. Dr. Gladys McGarey reminds us that medicine isn't just about curing disease — it's about nurturing the human spirit, and remembering that love itself is one of the most powerful healing forces we have.   We Also Discuss: (00:00) A Century of Healing: The Life and Legacy of Dr. Gladys McGarey (09:45) Growing Up in India and Meeting Gandhi (20:23) How Holistic Medicine Was Born, and Why It Still Matters (25:32) The Physician Within: What True Healing Really Means (27:20) Energy, Purpose, and the Secret to Staying "Alive" at Any Age (33:55) Turning Setbacks into Teachers: Finding Growth in Pain (37:46) Why Community Is the Medicine We're Missing (43:54) The Vision for a Healing Village, Where Love and Life Lead Medicine Thank You to Our Sponsor: IM8: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah:  Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Dr. Gladys McGarey: Website:https://gladysmcgarey.com/ Instagram: @livingmedicinedr

    40 min

  5. 30 OCT

    108. Dr. Vonda Wright: Why Women Need a New Approach to Aging, and How to Start Now

    What if the real turning point for women's health isn't menopause itself, but the decade before it?  Long before the symptoms hit, your brain, bones, and heart are already changing, silently. You can train hard, eat clean, and still lose strength, bone density, and cognitive sharpness if you're not addressing the biology underneath it all. In this episode of EXTEND, I'm joined by Dr. Vonda Wright, orthopedic surgeon, researcher, and author of Unbreakable, to talk about how women can take control of midlife long before the "change." We get into what actually happens when estradiol starts to fall, why bone is an active endocrine organ (not just structure), and how to measure what really predicts longevity: VO₂ max, grip strength, sit-to-stand, and bone quality. We also discuss her FACE framework, flexibility, aerobic base, carrying load, and equilibrium, a smarter way to train for longevity that protects your brain, bones, and hormones.  Dr. Vonda Wright is a double board-certified orthopedic surgeon, researcher, and author of Unbreakable. She's a leading expert in active aging and musculoskeletal longevity, known for helping midlife women build strength, preserve bone health, and optimize performance through data-driven prevention.  What's Discussed: (00:00) Why Women Need to Rethink Midlife Health (05:54) The Longevity Equation: Strength, Hormones, and Prevention (17:39) The Forgotten Organ Driving Women's Aging: Bone\ (28:44) How to Build Bone Quality (Not Just Density) (34:55) Training Smarter in Midlife: The FACE Protocol for Strength and Power (44:45) How to Find Real Fitness Inspiration Online, and Filter Out the Noise Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Dr. Vonda Wright:  Website: https://www.drvondawright.com/ Instagram: https://www.instagram.com/drvondawright

    45 min

  6. 28 OCT

    107. Dr. Will Cole: Gut Issues and Anxiety? Functional Medicine Is Finally Connecting the Dots

    You can eat clean, track your labs, take supplements, and still feel anxious, inflamed, tired, or flat. Why? Because the gut, brain, immune system, and hormones are in constant conversation, and most of us are only treating one side of that story. In this episode of Extend, I sit down with Dr. Will Cole to uncover the science behind the gut-brain axis, and why nervous system dysregulation might be the reason your biomarkers won't budge. We unpack how microbiome imbalances, silent inflammation, low vagal tone, and stored trauma show up as anxiety, constipation, brain fog, and burnout… even when you're "doing everything right." We also get practical: testing beyond standard blood work, HRV as a window into resilience, breathwork vs. meditation, EMDR, "ugly journaling," and when devices like Apollo Neuro and Sensate actually help. Dr. Will Cole is a leading functional medicine expert, a pioneer in gut-brain health, neuroimmune disorders, and autoimmune healing. He is also the host of the top-ranked podcast The Art of Being Well and the New York Times bestselling author of books including Gut Feelings, The Inflammation Spectrum, and Ketotarian. What's Discussed: (00:00) From Functional Medicine to the Gut-Brain Revolution (13:14) How Trauma, Serotonin, and the Vagus Nerve Shape the Mind-Gut Connection (21:13) Healing the Nervous System: Journaling, EMDR, and Wearable Vagus Nerve Tech (30:15) Why Real Health Change Starts with Individuals, Not Institutions (35:07) Food Deserts, Misinformation, and Taking Your Health Back (43:04) Regenerative Supplements, Soil Health & The Future of Functional Medicine   Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Dr. Will Cole: Instagram: @drwillcole Instagram: @theartofbeingwell_  Youtube: @DrWillCole

    45 min

  7. 23 OCT

    106. Siggi Clavien: Why Your Liver is Slowly Killing You (And You Don't Even Know It)

    You have brain fog. You're gaining weight faster and losing it slower. You think it's stress, aging, or just life… But what if it's your liver screaming for help? In this episode of Extend, I'm joined by Siggi Clavien, liver health expert and founder of The Liver Clinic, to uncover the silent epidemic destroying our health from the inside out. We explore why 70% of liver disease today has nothing to do with alcohol, the actual damage done by Tylenol, and why your "normal" blood work might be hiding liver damage. We also dive into technology that can detect damage years before blood tests, and what might be your key to reversing chronic disease. Siggi Clavien is a liver health specialist with 28 years in phytomedicine development and founder of The Liver Clinic. He combines ancient Eastern medicine wisdom with modern technology to help people detect and reverse liver damage. We Also Discuss: (00:00) Health and Liver Function Discussion (07:12) Toxins, Diet, and Fatty Liver Impact (17:13) Liver Damage Detection and Management (28:27) Toxic Exposure and Health Protection (37:28) Liver Health and Protection Strategies (45:17) Understanding Liver Scan Technology and Risks (56:20) Diet, Exercise, and Liver Health (01:00:56) Detoxification, Liver Health, and Deliverance (01:10:39) Liver Health Tracking and Advancements (01:16:36) Health Care Access and Support Thank you to our Sponsors: Timeline: Go to timeline.com/drshah to get 20% off your order.   Learn more about Dr. Shah: Website: https://www.drshah.com/  Clinic: https://www.next-health.com/ Instagram: @darshanshahmd   Learn more about Siggi Clavien: Website: https://us.loveyourliver.com/ https://theliverclinic.com/  Instagram: @deliverance.elixir @siggiclavien

    1h 15m

  8. 21 OCT

    105. Gabby Bernstein: Why Safety Is the Most Powerful Longevity Protocol

    We track our sleep, count our macros, optimize every supplement, yet most people's bodies are still stuck in survival mode. What if true longevity starts not with another biohack, but with safety? When your nervous system feels safe, inflammation drops, digestion normalizes, and recovery accelerates.  In this episode of Extend, I sit down with Gabby Bernstein, #1 New York Times bestselling author and host of the Dear Gabby podcast, to explore how emotional regulation, breathwork, and Internal Family Systems (IFS) therapy rewire the nervous system for resilience. Together, we break down how HRV reflects longevity, why "soft" tools like breath and meditation have hard science behind them, and how pairing spiritual practice with functional medicine creates lasting health transformation. Gabby Bernstein is a #1 New York Times bestselling author, host of the Dear Gabby podcast, and a leading teacher in self-help and spiritual development. For 20 years she's democratized tools like meditation, trauma-informed healing, and IFS for everyday life. In this episode, she shows us how to make emotional safety a daily practice, and why that might be the most powerful longevity intervention we have. What's Discussed: (00:00) From Burnout to Breakthrough: A Spiritual Path to Sobriety (03:39) What Safety Really Feels Like, and How to Create It (12:14) Turning Pain Into Peace: Healing Trauma Through Spiritual Practice (18:20) Meeting Your Protector Parts Instead of Fighting Them (30:42) Radical Self-Compassion as the Fastest Way to Heal (33:59) How to Reprogram Your Inner Protectors for Real Wellness (46:30) When Doctors Need Healing Too: Trauma Inside Medicine (51:22) Where Science Meets Spirit: The Biology of Belief (57:55) Faith, Energy, and the New Language of Healing (01:08:44) Manifestation as Medicine: How Your Mind Shapes Biology (01:14:49) The App That's Redefining Daily Spiritual Practice Thank You to Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Function Health: Learn more and join using functionhealth.com/drshah . The first 1000 get a $100 credit toward their membership. Visit www.functionhealth.com/drshah or use gift code DRSHAH100 at sign-up to own your health.   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Gabby Bernstein: Instagram: @gabbybernstein Website: https://gabbybernstein.com/ Book: 7 Habits of a Super Attractor: Effortlessly Attract Your Desires

    1h 18m
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About

Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan. Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results. That's why this podcast is all about cutting through the noise on how to turn back the aging clock. I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health. Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.

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