Data Commons — The Emerging Infrastructure of AI

In this episode of The Macro AI Podcast, Gary and Scott dive deep into the emerging concept of Data Commons — shared, governed ecosystems that make data interoperable, trusted, and ready for AI. 

They explain what a Data Commons is, how it differs from traditional data lakes, and why it’s essential to the next phase of AI transformation. From Google’s global Data Commons and the NIH’s biomedical repositories to emerging “Private Data Commons” inside enterprises, the hosts show how these ecosystems are reshaping trust, governance, and efficiency. 

Listeners will learn how Data Commons reduce AI hallucination, enable grounding, improve reproducibility, and support ethical AI. Gary and Scott also explore governance models, global equity, and the rise of AI agents that automatically fetch verified data from commons networks. 

If you’re a CIO, CTO, or business leader preparing your organization for AI, this episode offers the strategic framework you’ll need to understand the infrastructure of the future. 

🔗 Links mentioned: 

• Google Data Commons 
• Open Data Policy Lab — AI Data Commons Blueprint 
• Therapeutics Data Commons 
• NIH Data Commons 

Send a Text to the AI Guides on the show!

About your AI Guides

Gary Sloper

https://www.linkedin.com/in/gsloper/

Scott Bryan

https://www.linkedin.com/in/scottjbryan/

Macro AI Website:

https://www.macroaipodcast.com/

Macro AI LinkedIn Page:

https://www.linkedin.com/company/macro-ai-podcast/

Gary's Free AI Readiness Assessment:

https://macronetservices.com/events/the-comprehensive-guide-to-ai-readiness

Scott's Content & Blog

https://www.macronomics.ai/blog