Rings a Bell

kimberley Kallio

Are you a pharmacist/medical professional? Could you pass the national licensing exam for your profession if you had a pop quiz today? Me either! But I'd like to come close. In this podcast series, I, Kimberley Kallio will embarass myself by taking quizzes from my guests on all the important topics you need to know for your practice. Listen along and relearn your basics with me! Hosted on Acast. See acast.com/privacy for more information.

Episodes

  1. 26 May

    Episode 7 - Hypertension with Dr. Shelita Dattani

    The one, the only, Dr. Shelita Dattani quizzes Kim on the 2025 Hypertension Canada guidelines. Dr. Shelita Dattani is a nationally and internationally recognized pharmacy leader, advocate, and speaker with over 25 years of experience across community practice, hospital settings, academia, industry and national associations. Shelitta is on the board of Hypertension Canada and knows the 2025 Hypertension Canada guidelines inside and out. The full guidelines are available at hypertension.ca If you want to see references from this episode, follow the show on socials, sign up for the email list, donate via "buy me a coffee" or send me an email you can do so using this link: https://ringsabellpod.kit.com/allthethings Shelita can be found on LinkedIn here: https://www.linkedin.com/in/shelita-dattani-pharmd-a117aa1a/ or on instagram @shelsrx. You can also email Shelita at sdatrx@gmail.com. Here are the chapters for this episode: 00:00 - Introduction  04:00 - How big is the hypertension problem in Canada? 10:33 - How does Canada compare to the rest of the globe in terms of hypertension prevalence and management? 15:30 - The case for pharmacist management of uncomplicated hypertension. 19:14 - What is the recommended technique for measuring blood pressure according to the 2025 hypertension Canada guidelines? 22:37 - What proportion of people have white coat hypertension? 23:56 - What is masked hypertension? 24:13 - What is the gold standard for checking blood pressure? 25:52 - Why do we need to keep our feet flat on the floor when checking blood pressure? (and other tips for accurate blood pressure readings). 32:09 - The problem with blood pressure kiosks in pharmacies and the case for a counselling room pharmacist directed blood pressure measurement.  38:11 - What is the target blood pressure for everyone now? 41:54 - What is the number needed to harm for treating hypertension to 130/80 mmHg? 45:23 - What makes a person high cardiovascular risk and how do we treat their hypertension vs. someone with low cardiovascular risk? 48:36 - What are the recommendations for lifestyle interventions according to the 2025 Hypertension Canada Guidelines? 50:42 - Where do we get most of the sodium in our modern diets? 52:37 - What is the impact of alcohol on blood pressure? 56:51 - What is the pharmacotherapy strategy for treating hypertension according to the 2025 Hypertension Canada Guidelines? 1:03:00 - Do Angiotensin Receptor Blockers cause coughs? 1:04:00 - Can you use an ACE and an ARB together? 1:08:00 - Do we use beta blockers to control uncomplicated hypertension? 1:13:36 - Wrap up Hosted on Acast. See acast.com/privacy for more information.

    1hr 17min
  2. 17 Apr

    Episode 6 - Anxiety with Rami Safi

    Are you anxious about what you don’t remember about anxiety therapy? Well have I got a treat for you. Episode 6 of Rings A Bell Podcast! Rami Safi, a pharmacist and psychotherapist (qualifying) brings us the good bad and the ugly of anxiety management. Enjoy a comprehensive overview of pathophysiology, pharmacology and therapeutics with a few helpful tips for managing your own anxiety along the way! Topics Covered 00:00 - Introduction and housekeeping 00:44 - Rami’s journey from pharmacist to pharmacist and psychotherapist 07:22 - Pervasiveness and importance of anxiety 08:45 - Connection between perfectionism and anxiety 11:30 - Neurotransmitters involved in anxiety disorders 13:22 - Neurobiological difference between panic attack and generalized anxiety disorder 19:25 - Role of the amygdala in fear and anxiety 21:50 - First line treatments for generalized anxiety disorder 26:36 - Rapid nervous system regulation techniques 34:07 - St. John’s Wort risks in anxiety disorders 35:38 - Appropriate times to use benzodiazepines in anxiety treatment 36:11 - Managing side effects of selective serotonin reuptake inhibitors 37:45 - Importance of deprescribing benzodiazepines in elderly people 39:29 - Benzodiazepine pharmacokinetics (volume of distribution) (rate of clearance) (implications in obesity and elderly) 42:25 - Preferred benzodiazepines in elderly people 43:02 - Mechanism of action of buspirone 44:25 - Meds used in psychology with narrow therapeutic window 45:52 - Lithium and kidney function 47:49 - Serious drug interactions with SSRIs 48:45 - Intersection of chronic pain, depression and insomnia 50:35 - moral model of substance use vs. biopsychosocial model of substance use 56:34 - wrap up Connect with Rami Safi LinkedIn: https://www.linkedin.com/in/rami-s-98186718/ Wellness Wave Pharmacy in Hamilton: https://wellnesswavepharmacy.ca/  All the Links! Find all the links to all the things (references, resources, buy me a coffee, email list, etc) here: https://ringsabellpod.kit.com/allthethings  #anxiety #pathophysiology #pharmacology #anxietytherapeutics #therapeutics #continuingeducation#continuingeducation #pharmacy #pharmacylife #pharmacylyfe #pharmacistlife #pharmacistlyfe #itsmyanxiety #weallhaveanxiety #anxietymanagement #ssris #snris #serotonin #dopamine #norepinephrine #panicattacks #bzds #benzos #obesitymedicine #geriatricmedicine #benzodiazepines #diazepam #pharmacokinetics #volumeofdistribution #eliminationhalflife #neurology #psychotherapy #cbt #cognitivebehaviouraltherapy #GAD #generalizedanxietydisorder #SJW #stjohnswort #substanceuse Hosted on Acast. See acast.com/privacy for more information.

    59 min
  3. 08/10/2025

    Episode 3 Part 1: Metabolic Health with Dr. Alex Nataros

    Keywords: insulin sensitivity, metformin, blood sugar management, dietary approaches, microbiome, GLP-1 agonists, functional medicine, probiotics, metabolic health, clinical signs Summary: Episode 3 part 1 covers general metabolic health as it relates to pharmaceuticals, the microbiome and nutrition. My guest is Dr. Alex Nataros, a family doctor practicing in Port Hardy, BC. Subscribe to the Rings a Bell email list here: https://ringsabellpod.kit.com/subscribe To become a guest on the show email ringsabellpodcast@gmail.com References: Weight Gain Drugs https://pmc.ncbi.nlm.nih.gov/articles/PMC6109660/ Weight loss drugs https://mobile.fpnotebook.com/Endo/Pharm/MdctnsAsctdWthUntntnlWghtLs.htm Insulin Sensitivity Drugs Giglio RV, Papanas N, Rizvi AA, Ciaccio M, Patti AM, Ilias I, Pantea Stoian A, Sahebkar A, Janez A, Rizzo M. An Update on the Current and Emerging Use of Thiazolidinediones for Type 2 Diabetes. Medicina. 2022; 58(10):1475. https://doi.org/10.3390/medicina58101475 Laurindo LF, Barbalho SM, Guiguer EL, da Silva Soares de Souza M, de Souza GA, Fidalgo TM, Araújo AC, de Souza Gonzaga HF, de Bortoli Teixeira D, de Oliveira Silva Ullmann T, et al. GLP-1a: Going beyond Traditional Use. International Journal of Molecular Sciences. 2022; 23(2):739. https://doi.org/10.3390/ijms23020739 https://doi.org/10.1016/j.redox.2020.101517 (Mechanisms of Action of metformin in type 2 diabetes: effects on mitochondria and leukocyte endothelium interactions. Microbiome and obesity:  https://doi.org/10.1016/j.biopha.2022.112678 Sohail MU, Althani A, Anwar H, Rizzi R, Marei HE. Role of the Gastrointestinal Tract Microbiome in the Pathophysiology of Diabetes Mellitus. J Diabetes Res. 2017;2017:9631435. doi:10.1155/2017/9631435 HMF Metabolic: Michael DR, Jack AA, Masetti G, et al. A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being. Sci Rep. 2020;10(1):4183. Published 2020 Mar 6. doi:10.1038/s41598-020-60991-7 UltraFlora Control: Stenman LK, Lehtinen MJ, Meland N, et al. Probiotic With or Without Fiber Controls Body Fat Mass, Associated With Serum Zonulin, in Overweight and Obese Adults-Randomized Controlled Trial. EBioMedicine. 2016;13:190-200. doi:10.1016/j.ebiom.2016.10.036 Super intense study on personalized nutrition published in cell that I talked too long about :) Zeevi D, Korem T, Zmora N, et al. Personalized Nutrition by Prediction of Glycemic Responses. Cell. 2015;163(5):1079-1094. doi:10.1016/j.cell.2015.11.001                 Hosted on Acast. See acast.com/privacy for more information.

    50 min
  4. 01/08/2025

    Episode 2 - Constipation with Shelley Stepanuik

    References from Shelley:- UpToDate as referenced summer 2025   - RxFiles 2023 edition   - Bristol Stool Chart   - probioticchart.ca   - Why you should be careful with psyllium husk fiber supplement. YouTube:  https://youtu.be/mPHXldh4_H4?si=wtAMhpP2QDCxPlr6   - Cascara Sagrada withdrawal in USA https://www.fda.gov/about-fda/fda-history-exhibits/drug-therapeutics-regulation-us#   - Phenothalein withdrawal from market https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/phenolphthalein#   - Bisacodyl  Neurogastroenterol Motil. 2021 Mar 9;33(10):e14123. doi: 10.1111/nmo.14123   Bisacodyl: A review of pharmacology and clinical evidence to guide use in clinical practice in patients with constipation   Maura Corsetti 1,2,, Sabine Landes 3, Robert Lange 4 PMCID: PMC8596401 PMID: 33751780 https://pmc.ncbi.nlm.nih.gov/articles/PMC8596401/   - Stimulant laxatives    First published online June 16, 2024 Review article: do stimulant laxatives damage the gut? A critical analysis of current knowledge Peter Whorwell https://orcid.org/0000-0002-5220-8474 peter.whorwell@mft.nhs.uk, Robert Lange, and Carmelo Scarpignato    https://doi.org/10.1177/17562848241249664   - Rhubarb  https://pmc.ncbi.nlm.nih.gov/articles/PMC8321582/#   - Demulcents https://www.sciencedirect.com/topics/neuroscience/demulcent#   References from Kim:Lexicomp drug information for: podophyllum, wheat dextrin, phenolpthalein, polyethylene glycol 3350 https://time.com/archive/6617019/medicine-cut-out-the-liver/ Pharmacology, toxicology, clinical efficacy, and adverse effects of calcium polycarbophil, an enteral hydrosorptive agent. PMID: 6765389 Hosted on Acast. See acast.com/privacy for more information.

    1hr 17min

About

Are you a pharmacist/medical professional? Could you pass the national licensing exam for your profession if you had a pop quiz today? Me either! But I'd like to come close. In this podcast series, I, Kimberley Kallio will embarass myself by taking quizzes from my guests on all the important topics you need to know for your practice. Listen along and relearn your basics with me! Hosted on Acast. See acast.com/privacy for more information.

You Might Also Like