Talk Python To Me

Michael Kennedy

Talk Python to Me is a weekly podcast hosted by developer and entrepreneur Michael Kennedy. We dive deep into the popular packages and software developers, data scientists, and incredible hobbyists doing amazing things with Python. If you're new to Python, you'll quickly learn the ins and outs of the community by hearing from the leaders. And if you've been Pythoning for years, you'll learn about your favorite packages and the hot new ones coming out of open source.

  1. 21 UUR GELEDEN

    Celebrating Django's 20th Birthday With Its Creators

    Twenty years after a scrappy newsroom team hacked together a framework to ship stories fast, Django remains the Python web framework that ships real apps, responsibly. In this anniversary roundtable with its creators and long-time stewards: Simon Willison, Adrian Holovaty, Will Vincent, Jeff Triplett, and Thibaud Colas, we trace the path from the Lawrence Journal-World to 1.0, DjangoCon, and the DSF; unpack how a BSD license and a culture of docs, tests, and mentorship grew a global community; and revisit lessons from deployments like Instagram. We talk modern Django too: ASGI and async, HTMX-friendly patterns, building APIs with DRF and Django Ninja, and how Django pairs with React and serverless without losing its batteries-included soul. You’ll hear about Django Girls, Djangonauts, and the Django Fellowship that keep momentum going, plus where Django fits in today’s AI stacks. Finally, we look ahead at the next decade of speed, security, and sustainability. Episode sponsors Talk Python Courses Python in Production Links from the show Guests Simon Willison: simonwillison.net Adrian Holovaty: holovaty.com Will Vincent: wsvincent.com Jeff Triplett: jefftriplett.com Thibaud Colas: thib.me Show Links Django's 20th Birthday Reflections (Simon Willison): simonwillison.net Happy 20th Birthday, Django! (Django Weblog): djangoproject.com Django 2024 Annual Impact Report: djangoproject.com Welcome Our New Fellow: Jacob Tyler Walls: djangoproject.com Soundslice Music Learning Platform: soundslice.com Djangonaut Space Mentorship for Django Contributors: djangonaut.space Wagtail CMS for Django: wagtail.org Django REST Framework: django-rest-framework.org Django Ninja API Framework for Django: django-ninja.dev Lawrence Journal-World: ljworld.com Watch this episode on YouTube: youtube.com Episode #518 deep-dive: talkpython.fm/518 Episode transcripts: talkpython.fm Developer Rap Theme Song: Served in a Flask: talkpython.fm/flasksong --- Stay in touch with us --- Subscribe to Talk Python on YouTube: youtube.com Talk Python on Bluesky: @talkpython.fm at bsky.app Talk Python on Mastodon: talkpython Michael on Bluesky: @mkennedy.codes at bsky.app Michael on Mastodon: mkennedy

    1u 8m
  2. 22 AUG

    Agentic Al Programming with Python

    Agentic AI programming is what happens when coding assistants stop acting like autocomplete and start collaborating on real work. In this episode, we cut through the hype and incentives to define “agentic,” then get hands-on with how tools like Cursor, Claude Code, and LangChain actually behave inside an established codebase. Our guest, Matt Makai, now VP of Developer Relations at DigitalOcean, creator of Full Stack Python and Plushcap, shares hard-won tactics. We unpack what breaks, from brittle “generate a bunch of tests” requests to agents amplifying technical debt and uneven design patterns. Plus, we also discuss a sane git workflow for AI-sized diffs. You’ll hear practical Claude tips, why developers write more bugs when typing less, and where open source agents are headed. Hint: The destination is humans as editors of systems, not just typists of code. Episode sponsors Posit Talk Python Courses Links from the show Matt Makai: linkedin.com Plushcap Developer Content Analytics: plushcap.com DigitalOcean Gradient AI Platform: digitalocean.com DigitalOcean YouTube Channel: youtube.com Why Generative AI Coding Tools and Agents Do Not Work for Me: blog.miguelgrinberg.com AI Changes Everything: lucumr.pocoo.org Claude Code - 47 Pro Tips in 9 Minutes: youtube.com Cursor AI Code Editor: cursor.com JetBrains Junie: jetbrains.com Claude Code by Anthropic: anthropic.com Full Stack Python: fullstackpython.com Watch this episode on YouTube: youtube.com Episode #517 deep-dive: talkpython.fm/517 Episode transcripts: talkpython.fm Developer Rap Theme Song: Served in a Flask: talkpython.fm/flasksong --- Stay in touch with us --- Subscribe to Talk Python on YouTube: youtube.com Talk Python on Bluesky: @talkpython.fm at bsky.app Talk Python on Mastodon: talkpython Michael on Bluesky: @mkennedy.codes at bsky.app Michael on Mastodon: mkennedy

    1u 17m
  3. 19 AUG

    Accelerating Python Data Science at NVIDIA

    Python’s data stack is getting a serious GPU turbo boost. In this episode, Ben Zaitlen from NVIDIA joins us to unpack RAPIDS, the open source toolkit that lets pandas, scikit-learn, Spark, Polars, and even NetworkX execute on GPUs. We trace the project’s origin and why NVIDIA built it in the open, then dig into the pieces that matter in practice: cuDF for DataFrames, cuML for ML, cuGraph for graphs, cuXfilter for dashboards, and friends like cuSpatial and cuSignal. We talk real speedups, how the pandas accelerator works without a rewrite, and what becomes possible when jobs that used to take hours finish in minutes. You’ll hear strategies for datasets bigger than GPU memory, scaling out with Dask or Ray, Spark acceleration, and the growing role of vector search with cuVS for AI workloads. If you know the CPU tools, this is your on-ramp to the same APIs at GPU speed. Episode sponsors Posit Talk Python Courses Links from the show RAPIDS: github.com/rapidsai Example notebooks showing drop-in accelerators: github.com Benjamin Zaitlen - LinkedIn: linkedin.com RAPIDS Deployment Guide (Stable): docs.rapids.ai RAPIDS cuDF API Docs (Stable): docs.rapids.ai Asianometry YouTube Video: youtube.com cuDF pandas Accelerator (Stable): docs.rapids.ai Watch this episode on YouTube: youtube.com Episode #516 deep-dive: talkpython.fm/516 Episode transcripts: talkpython.fm Developer Rap Theme Song: Served in a Flask: talkpython.fm/flasksong --- Stay in touch with us --- Subscribe to Talk Python on YouTube: youtube.com Talk Python on Bluesky: @talkpython.fm at bsky.app Talk Python on Mastodon: talkpython Michael on Bluesky: @mkennedy.codes at bsky.app Michael on Mastodon: mkennedy

    1u 6m
  4. 11 AUG

    Durable Python Execution with Temporal

    What if your code was crash-proof? That's the value prop for a framework called Temporal. Temporal is a durable execution platform that enables developers to build scalable applications without sacrificing productivity or reliability. The Temporal server executes units of application logic called Workflows in a resilient manner that automatically handles intermittent failures, and retries failed operations. We have Mason Egger from Temporal on to dive into durable execution. Episode sponsors Posit PyBay Talk Python Courses Links from the show Just Enough Python for Data Scientists Course: talkpython.fm Temporal Durable Execution Platform: temporal.io Temporal Learn Portal: learn.temporal.io Temporal GitHub Repository: github.com Temporal Python SDK GitHub Repository: github.com What Is Durable Execution, Temporal Blog: temporal.io Mason on Bluesky Profile: bsky.app Mason on Mastodon Profile: fosstodon.org Mason on Twitter Profile: twitter.com Mason on LinkedIn Profile: linkedin.com X Post by @skirano: x.com Temporal Docker Compose GitHub Repository: github.com Building a distributed asyncio event loop (Chad Retz) - PyTexas 2025: youtube.com Watch this episode on YouTube: youtube.com Episode #515 deep-dive: talkpython.fm/515 Episode transcripts: talkpython.fm Developer Rap Theme Song: Served in a Flask: talkpython.fm/flasksong --- Stay in touch with us --- Subscribe to Talk Python on YouTube: youtube.com Talk Python on Bluesky: @talkpython.fm at bsky.app Talk Python on Mastodon: talkpython Michael on Bluesky: @mkennedy.codes at bsky.app Michael on Mastodon: mkennedy

    1u 11m
  5. 18 JUL

    Python Language Summit 2025

    Every year the core developers of Python convene in person to focus on high priority topics for CPython and beyond. This year they met at PyCon US 2025. Those meetings are closed door to keep focused and productive. But we're lucky that Seth Michael Larson was in attendance and wrote up each topic presented and the reactions and feedback to each. We'll be exploring this year's Language Summit with Seth. It's quite insightful to where Python is going and the pressing matters. Episode sponsors Seer: AI Debugging, Code TALKPYTHON Sentry AI Monitoring, Code TALKPYTHON Talk Python Courses Links from the show Seth on Mastodon: @sethmlarson@fosstodon.org Seth on Twitter: @sethmlarson Seth on Github: github.com Python Language Summit 2025: pyfound.blogspot.com WheelNext: wheelnext.dev Free-Threaded Wheels: hugovk.github.io Free-Threaded Python Compatibility Tracking: py-free-threading.github.io PEP 779: Criteria for supported status for free-threaded Python: discuss.python.org PyPI Data: py-code.org Senior Engineer tries Vibe Coding: youtube.com Watch this episode on YouTube: youtube.com Episode #514 deep-dive: talkpython.fm/514 Episode transcripts: talkpython.fm Developer Rap Theme Song: Served in a Flask: talkpython.fm/flasksong --- Stay in touch with us --- Subscribe to Talk Python on YouTube: youtube.com Talk Python on Bluesky: @talkpython.fm at bsky.app Talk Python on Mastodon: talkpython Michael on Bluesky: @mkennedy.codes at bsky.app Michael on Mastodon: mkennedy

    1u 13m
  6. 25 JUN

    From Notebooks to Production Data Science Systems

    If you're doing data science and have mostly spent your time doing exploratory or just local development, this could be the episode for you. We are joined by Catherine Nelson to discuss techniques and tools to move your data science game from local notebooks to full-on production workflows. Episode sponsors Agntcy Sentry Error Monitoring, Code TALKPYTHON Talk Python Courses Links from the show New Course: LLM Building Blocks for Python: training.talkpython.fm Catherine Nelson LinkedIn Profile: linkedin.com Catherine Nelson Bluesky Profile: bsky.app Enter to win the book: forms.google.com Going From Notebooks to Scalable Systems - PyCon US 2025: us.pycon.org Going From Notebooks to Scalable Systems - Catherine Nelson – YouTube: youtube.com From Notebooks to Scalable Systems Code Repository: github.com Building Machine Learning Pipelines Book: oreilly.com Software Engineering for Data Scientists Book: oreilly.com Jupytext - Jupyter Notebooks as Markdown Documents: github.com Jupyter nbconvert - Notebook Conversion Tool: github.com Awesome MLOps - Curated List: github.com Watch this episode on YouTube: youtube.com Episode #511 deep-dive: talkpython.fm/511 Episode transcripts: talkpython.fm Developer Rap Theme Song: Served in a Flask: talkpython.fm/flasksong --- Stay in touch with us --- Subscribe to Talk Python on YouTube: youtube.com Talk Python on Bluesky: @talkpython.fm at bsky.app Talk Python on Mastodon: talkpython Michael on Bluesky: @mkennedy.codes at bsky.app Michael on Mastodon: mkennedy

    54 min

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Info

Talk Python to Me is a weekly podcast hosted by developer and entrepreneur Michael Kennedy. We dive deep into the popular packages and software developers, data scientists, and incredible hobbyists doing amazing things with Python. If you're new to Python, you'll quickly learn the ins and outs of the community by hearing from the leaders. And if you've been Pythoning for years, you'll learn about your favorite packages and the hot new ones coming out of open source.

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