MEET THE GUEST Dr. Chris Renna, DO is one of the nation's foremost leaders in preventive and longevity medicine and the founder of LifeSpan Medicine, established in 1992, with flagship clinics in Santa Monica, Miami, and Dallas. Board-certified in family medicine and a cum laude graduate of the University of North Texas Health Science Center, he realized early that traditional medical training was designed to treat disease, not create health. He draws from advanced diagnostics, functional medicine, and deep clinical insight to craft personalized protocols for patients who have often tried everything else. He is the author of The End of Pain and Balance Your Brain, Balance Your Life, has presented at the Global Wellness Summit, and has been featured in outlets ranging from goop to The Atlantic. WHAT WE TALK ABOUT Dr. Renna's pivot from disease treatment to preventive medicine after five years in conventional practiceSelf-education in diet, exercise physiology, sleep science, and motivational psychology during the 1980sThe founding of LifeSpan Medicine in 1992 and the shift to seeing patients as clients and equalsLifespan vs. health span and why functional longevity matters more than simply living longerSetting concrete longevity goals, including remaining physically and cognitively active into your 90sThe four cornerstones of health: diet, exercise, sleep, and mental perspectiveHow the immune, hormonal, and neurochemical systems function as one integrated system rather than separatelyCognitive decline prevention through mindset, acceptance, and reducing chronic low-grade inflammationHow the decade between ages 45 and 55 is the most health-critical due to declining reproductive hormonesBioidentical hormone replacement therapy for both men and women and its benefits for strength, cognition, and disease preventionMetabolic health, insulin resistance, and the cascade of problems associated with metabolic syndromeThe importance of nutrient-dense, home-prepared, locally sourced food and quality cooking oilsGenetics as a limit-setter rather than a life sentence, and how lifestyle choices shape epigenetic expressionBiological age testing and how genomic adaptability declines with age and poor lifestyle habitsWhat healthy aging actually looks like through your 50s, 60s, and beyond with consistent habitsCore supplements to consider: omega-3 oils, a quality multivitamin, and vitamin DHow exercise in your 50s, including resistance training and flexibility work, determines your biological age at 70 and beyond EPISODE RESOURCES Integrative Peptides Cellular repair is the foundation of healthy aging. Pure, consistent peptide support to help you get there. Use code TRAILTOHEALTH for 10% off. https://shop.thetrailtohealth.com/IntegrativePeptides StemRegen More circulating stem cells means more raw material for the cellular repair and regeneration that keeps you functioning longer. https://shop.thetrailtohealth.com/StemRegen Heart and Soil Supplements The most nutrient-dense foods your body can get, in supplement form. Use code TRAILTOHEALTH for 10% off. https://shop.thetrailtohealth.com/HeartandSoil Prolon The only nutrition program clinically shown to reverse biological age. Use code TRAILTOHEALTH for 20% off. https://shop.thetrailtohealth.com/prolon Genopalate Metabolic health starts with knowing how your body processes food at a genetic level. Use code TRAILTOHEALTH for 10% off. https://shop.thetrailtohealth.com/genopalate CONNECT WITH THE GUEST Website: https://www.lifespanmedicine.com/ Instagram: https://www.instagram.com/lifespanmedicine Facebook: https://www.facebook.com/lifespanmedicineMD KEYWORDS longevity medicine, health span, biological age, metabolic health, hormone replacement, peptides, stem cells, nutrient density, cognitive decline, epigenetics, insulin resistance, preventive medicine, omega-3, vitamin D, bioidentical hormones, aging well