Joint Action

David Hunter, PhD, FRACP (Rheum)

Joint Action is a podcast hosted by David Hunter. As a consequence of isolation, those living with osteoarthritis related disability may become less fit, more depressed and anxious, more socially isolated and gain weight. It is critical at times like this that people with osteoarthritis have their burden and disability minimised and their knowledge of how to manage the disease enhanced. Join David as he interviews the world's leading experts in osteoarthritis. Professor David Hunter is a rheumatology clinician researcher whose main research focus has been clinical and translational research in osteoarthritis. He is the Florance and Cope Chair of Rheumatology and Professor of Medicine at University of Sydney and the Royal North Shore Hospital, Sydney, Australia. He is ranked as the worlds leading expert in osteoarthritis on Expertscape.com since 2014. ​ You can send in your questions to hello@jointaction.info and follow David on Instagram at @ProfDavidHunter. To learn more about our research, visit our website at https://www.osteoarthritisresearch.com.au/ Hosted on Acast. See acast.com/privacy for more information.

  1. 26 OCT

    Cycling and hip osteoarthritis: Evidence and insights with Professor Tom Wainwright

    Can two wheels really help ease joint pain? On this week's episode we are joined by Professor Tom Wainwright to discuss the benefits of cycling for hip osteoarthritis. He also discusses the findings of his recently completed randomised controlled trial comparing a cycling and educational intervention to usual physiotherapy care. Professor Tom Wainwright is a physiotherapist specialising in orthopaedic physiotherapy, researcher and educator. He has authored over 150 peer-reviewed publications is recognised as an international expert in Enhanced Recovery After Surgery (ERAS) protocols in Orthopaedics and was the lead author of the first ERAS Society guidelines for hip and knee replacement.   Tom is passionate about improving the quality of healthcare systems and works to help other healthcare providers improve the quality of their services through teaching and consultancy. RESOURCES ORI Education App - ORI Education shares online learning courses to those with an interest in osteoarthritis and orthopaedic surgery. These courses are informed by the latest research and professional thinking from our institute, along with research evidence from across the globe.CHAIN (Cycling against Hip pAIN)Journal Articles Clinical and cost-effectiveness of a cycling and education intervention versus usual physiotherapy care for the treatment of hip osteoarthritis in the UK (CLEAT): a pragmatic, randomised, controlled trialCONNECT WITH US Join one of our trials https://www.osteoarthritisresearch.com.au/current-trialsInstagram: @ProfDavidHunterTwitter: @ProfDavidHunter @jointactionorgEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcast If you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.

    33 min
  2. 28 SEPT

    Can knee realignment slow down osteoarthritis? A discussion with Dr Trevor Birmingham and Dr David Parker

    High tibial osteotomy (HTO) is a limb realignment surgery which is intended for people who have medial compartment osteoarthritis (OA), but are not suitable candidates for total knee replacement due to younger age, less severe disease and greater physical demands. The aim of HTO is to correct alignment, thereby shifting load away from the more involved knee compartment and limit progression of knee OA. On this week's episode of Joint Action, we are joined by Dr Trevor Birmingham and Dr David Parker to discuss high tibial osteotomy surgery, who it is suitable for and the risks involved. Professor Trevor Birmingham is a physiotherapist and Canada Research Chair in Musculoskeletal Rehabilitation at the University of Western Ontario in London, Canada. He leads research on musculoskeletal health, often combining clinical outcomes with biomechanical, imaging and biological measures in cohort studies and randomized trials. He co-directs the Wolf Orthopaedic Biomechanics Lab at the Fowler Kennedy Sport Medicine Clinic and is a founding member of the Bone and Joint Institute and the Collaborative Graduate Training Program in Musculoskeletal Health Research at Western University.   Dr David Parker is an experienced orthopaedic knee specialist and co-founder of the Sydney Orthopaedic Research Institute (SORI). He is passionate about sport and is actively involved with international orthopaedic and sports medicine organisations and has extensive experience with athletes of all levels from recreational to elite. Dr Parker has authored over 100 peer-reviewed publications and many textbook chapters and has been awarded the Australian Orthopaedic Association Prize for Research.  RESOURCES Journal articles Total knee replacement after high tibial osteotomy: time-to-event analysis and predictors CONNECT WITH US Join one of our trials https://www.osteoarthritisresearch.com.au/current-trialsTwitter: @ProfDavidHunter @jointactionorgEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcast If you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.

    28 min
  3. 14 SEPT

    In Memoriam: Prof Frank Beier - new insights into osteoarthritis onset (2021)

    This week's episode is in honour of Frank Beier, who recently passed away on July 18, 2025. Frank leaves behind a remarkable legacy through the impact he made in the field of osteoarthritis. In this previous episode (2021), he discussed the recent advances in osteoarthritis understanding with a particular emphasis on novel targets and epigenetics. Despite the large prevalence of osteoarthritis, there is no clinically approved drug which provides a cure. Currently, drugs focus on relieving symptoms such as pain. Experiments done in the laboratory have provided insight on osteoarthritis onset and progression and will likely guide therapeutic development.   We know that osteoarthritis is a disease of the whole organ meaning that any of the tissues involved in the synovial joint can be affected. The interplay between the various cell types involved is complex and understanding the interactions between cartilage, bone and synovium may be critical to therapeutic development.   Skeletal development likely plays a very important role in predisposition to disease. Through the identification of serious pathologies such as various forms of dwarfism (what in medical terms are called chondrodysplasias) the role of transcription factors and epigenetics is increasing our understanding of disease genesis.The study of the epigenetics of OA - the mechanism by which the human genome alters it’s gene expression (without changing the primary DNA sequence) has provided valuable information on novel risk factors for the disease and are potential therapeutic targets for OA. RESOURCES Journal articles Nuclear receptors as potential drug targets in osteoarthritisInterplay between genetics and epigenetics in osteoarthritisRecent developments in emerging therapeutic targets of osteoarthritis CONNECT WITH US Twitter: @ProfDavidHunter @jointactionorgEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcast If you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.

    29 min

About

Joint Action is a podcast hosted by David Hunter. As a consequence of isolation, those living with osteoarthritis related disability may become less fit, more depressed and anxious, more socially isolated and gain weight. It is critical at times like this that people with osteoarthritis have their burden and disability minimised and their knowledge of how to manage the disease enhanced. Join David as he interviews the world's leading experts in osteoarthritis. Professor David Hunter is a rheumatology clinician researcher whose main research focus has been clinical and translational research in osteoarthritis. He is the Florance and Cope Chair of Rheumatology and Professor of Medicine at University of Sydney and the Royal North Shore Hospital, Sydney, Australia. He is ranked as the worlds leading expert in osteoarthritis on Expertscape.com since 2014. ​ You can send in your questions to hello@jointaction.info and follow David on Instagram at @ProfDavidHunter. To learn more about our research, visit our website at https://www.osteoarthritisresearch.com.au/ Hosted on Acast. See acast.com/privacy for more information.

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