1分钟轻松播客 为什么有的人喝咖啡能提神，有的人却更困？

Have you ever wondered why some people feel wide awake after a cup of coffee… while others end up even more sluggish？

It all comes down to how our bodies respond to caffeine. Normally, when we feel tired, a chemical called adenosine accumulates in the brain and creates a sense of drowsiness. Caffeine temporarily blocks those receptors, so most people feel more alert.

But not everyone reacts in the same way. Some people carry genetic variations that make them metabolize caffeine rapidly — they enjoy a short but powerful energy boost. Others are slow metabolizers, so caffeine lingers in their system, leaving them jittery, anxious… or paradoxically, even more fatigued.

Timing is crucial as well. If you drink coffee immediately after waking, when your cortisol levels are already elevated, the effect is minimal. And consuming it too late in the day can disrupt your sleep cycle, leaving you more exhausted the next morning.

So next time coffee makes you tired, remember — it might be your genetics, your timing, or simply the fact that what you really need isn’t caffeine, but genuine rest.