The Incubator

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2D AGO

#396 - [Journal Club] - 📌 Surfactant Thresholds: Is 40% FiO2 as Safe as 30%?

Send a text In this episode of Journal Club, Ben and Daphna review a non-inferiority trial from the European Journal of Pediatrics exploring surfactant administration thresholds in preterm neonates. The study, conducted in India, compares a 30% versus 40% FiO2 threshold for babies 26-32 weeks gestational age. The hosts break down the counterintuitive findings regarding respiratory support duration in younger subgroups and discuss the broader implications of using rigid FiO2 heuristics versus individualized patient assessment. They also debate how resource availability influences clinical protocols and the potential benefits of "LISA" (Less Invasive Surfactant Administration) for avoiding intubation. ---- Higher (40%) versus lower (30%) FiO2 threshold for surfactant administration in preterm neonates between 26 and 32 weeks of gestational age: a non-inferiority randomized controlled trial. Haq MI, Datta V, Bandyopadhyay T, Nangia S, Anand P, Murukesan VM.Eur J Pediatr. 2025 Nov 25;184(12):793. doi: 10.1007/s00431-025-06628-1.PMID: 41288797 Clinical Trial. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

2d ago

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16 min
3D AGO

#396 - [Journal Club] - 📌 TORPIDO 30/60: Is Higher Initial Oxygen Safer for Preterm Infants?

Send us a text In this episode of The Incubator, Ben and Daphna return from the Delphi Conference to dive back into Journal Club. They review the highly anticipated TORPIDO 30/60 trial published in JAMA, comparing initial oxygen concentrations of 30% versus 60% for preterm resuscitation. The hosts discuss the primary outcomes of survival and brain injury, while highlighting intriguing secondary findings regarding chest compressions and epinephrine use in the delivery room. They also share exciting updates on the Vermont Oxford Network collaboration and a new family study from the GFCNI. ---- Targeted Oxygen for Initial Resuscitation of Preterm Infants: The TORPIDO 30/60 Randomized Clinical Trial. Oei JL, Kirby A, Travadi J, Davis P, Wright I, Ghadge A, Yeung C, Cruz M, Keech A, Hague W, Lui K, Vento M, Gordon A, De Waal K, Chaudhari T, Hong TSL, Morris S, Kushnir A, Bonney D, Tracy M, Kumar K, Chhnia AS, Baral VR, Muniyappa P, Cheah FC, Sarnadgouda P, Rajadurai VS, Balakrishnan U, Oleti TP, Aldecoa-Bilbao V, Couce ML, Collados CT, Fernández RE, Moliner E, Ruiz Gonzalez MD, Singhal M, Agrawal G, Singh J, Pal S, Nayya S, Arora R, Amboiram P, Simes J, Tarnow-Mordi W; TORPIDO30/60 Collaborative Group.JAMA. 2025 Dec 10:e2523327. doi: 10.1001/jama.2025.23327. Online ahead of print.PMID: 41369162 Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

3d ago

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21 min
JAN 29

#395 - [DELPHI PANEL] - How is Artificial Intelligence Transforming Neonatal Care?

Send us a text This recording captures the AI panel discussion from the 2026 Delphi Neonatal Innovation Conference, held live on Monday afternoon. Dr. Jim Barry (University of Colorado), Dr. Thao Ho (UCSF), Lindsey Knake (University of Iowa), Selva Selvaraj (Nicklaus Children's Health System), and Dr. Ryan McAdams (University of Wisconsin-Madison) discuss where AI stands in the NICU today. The panelists cover predictive models for sepsis and NEC, AI documentation tools, and the gap between research prototypes and clinical implementation. They address challenges with generalizability across different units, ethical considerations, parent-facing AI applications, and what might be standard practice in ten years. If you're trying to figure out what's actually working versus what's still theoretical, this conversation covers the current state of play. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Jan 29

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1h 6m
1D AGO

#396 - [Journal Club] - 📌 The 6-Fold Risk of NEC in Growth Restricted Infants

Send a text In this episode of Journal Club, Ben and Daphna review a prospective cohort study from the Journal of Perinatology that examines the care of neonates following in-utero growth restriction. The hosts unpack the critical distinction between Fetal Growth Restriction (FGR) and Small for Gestational Age (SGA), highlighting how the "decay of information" in the NICU can lead clinicians to overlook early risk factors as babies grow. They discuss the study’s alarming findings regarding the six-fold increased risk of Necrotizing Enterocolitis (NEC) in SGA infants and the importance of maintaining a comprehensive medical history throughout a patient's stay. ---- Care of neonates following in-utero growth restriction: A prospective cohort study exploring neonatal morbidity. Alda MG, Wood AG, MacDonald T, Charlton JK.J Perinatol. 2025 Sep;45(9):1219-1225. doi: 10.1038/s41372-025-02397-9. Epub 2025 Aug 21.PMID: 40841433 Free PMC article. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

1d ago

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18 min
JAN 21 • SUBSCRIBERS ONLY

#130 - 🤰MFM - Questions: 11, 13, 17, 18

To learn more and have access to show notes and articles mentioned in this episode, go to www.the-incubator.org/review Please subscribe to the podcast for access to daily episodes. If you have any questions feel free to email the show at nicupodcast@gmail.com You can also contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd.

Jan 21

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11 min
3D AGO

#055 - 📑 Journal Club - Les derniers articles de recherche en néonatologie (9 février 2026)

Dans cet épisode de Journal Club, Ben et Gabriel discutent de cinq études récentes. Une étude norvégienne démontre qu'un examen physique sériel réduit l'exposition aux antibiotiques de 50% sans compromettre la sécurité. Un essai coréen montre que la bêta-méthasone entre 34-36 semaines réduit la détresse respiratoire chez les jumeaux mais augmente les hypoglycémies. Une étude torontoise identifie le NT-Pro BNP comme biomarqueur d'hypertension pulmonaire chez les grands prématurés. Deux études explorent l'intelligence artificielle : l'une utilise l'imagerie rétinienne pour prédire dysplasie bronchopulmonaire et HTAP, l'autre démontre qu'un score EEG automatisé peut prédire les issues neurodéveloppementales à deux ans chez les nouveau-nés avec encéphalopathie hypoxique-ischémique. ---- Antenatal Corticosteroid in Twin-Pregnant Women at Risk of Late Preterm Delivery: A Randomized Clinical Trial.Lee SM, Park HS, Choi SR, Lee J, Kim HJ, Park JY, Oh KJ, Cho GJ, Oh MJ, Chung JH, Kim SM, Kim BJ, Kim SY, Hong S, Jung YM, Lee SJ, Seong JS, Kim H, Oh S, Lee J, Jin YR, Kim JH, Cho HY, Park CW, Park JS, Jun JK.JAMA Pediatr. 2025 Dec 1;179(12):1275-1282. doi: 10.1001/jamapediatrics.2025.3284.PMID: 40982289 Clinical Trial. Deep Learning-Based Prediction of Cardiopulmonary Disease in Retinal Images of Premature Infants. Singh P, Kumar S, Tyagi R, Young BK, Jordan BK, Scottoline B, Evers PD, Ostmo S, Coyner AS, Lin WC, Gupta A, Erdogmus D, Chan RVP, McCourt EA, Barry JS, McEvoy CT, Chiang MF, Campbell JP, Kalpathy-Cramer J.JAMA Ophthalmol. 2026 Jan 22:e255814. doi: 10.1001/jamaophthalmol.2025.5814. Online ahead of print.PMID: 41569552 Can N-terminal pro-brain natriuretic peptide accurately diagnose chronic pulmonary hypertension among extremely low gestational age neonates: A Retrospective Cohort Study. Garcia-Gozalo M, Jain A, Weisz DE, Jasani B.J Perinatol. 2025 Nov 13. doi: 10.1038/s41372-025-02462-3. Online ahead of print.PMID: 41233504 Serial physical examination to reduce unnecessary antibiotic exposure in newborn infants: a population-based study. Vatne A, Eriksen BHH, Bergqvist F, Fagerli I, Guthe HJT, Iversen KV, Ud Din FS, van der Weijde J, Kvaløy JT, Rettedal S.Arch Dis Child Fetal Neonatal Ed. 2025 Nov 19:fetalneonatal-2025-329639. doi: 10.1136/archdischild-2025-329639. Online ahead of print.PMID: 41260908 Automated EEG Background Analysis and 2-Year Outcomes in Neonatal Hypoxic-Ischemic Encephalopathy. Cornet MC, Numis AL, Wusthoff CJ, Bernardo D, Mietzsch U, Thomas C, Natarajan N, Ahmad KA, Scheffler A, Juul SE, Montazeri Moghadam S, Wu YW, Glass HC.JAMA Netw Open. 2025 Dec 1;8(12):e2548321. doi: 10.1001/jamanetworkopen.2025.48321.PMID: 41400952 Comme d'habitude, n'hésitez pas à nous envoyer vos questions, commentaires ou suggestions à notre courriel : nicupodcast@gmail.com. Vous pouvez également contacter l'émission via Instagram ou Twitter, @nicupodcast Ou contactez Ben et Gabriel directement via leurs profils Twitter : @drnicu et @CardioNeo. Les documents discutés dans l'épisode d'aujourd'hui sont listés et horodatés sur la page web liée ci-dessous. Bonne lecture ! _____________________________________________________________________________________ Les notes de l'émission, les articles et le formulaire de FMC sont disponibles sur notre site Web : www.lincubateur.org

3d ago

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1h 8m
23 HRS AGO

#396 - [Journal Club] - 📌 Cooling Late Preterms: Higher Mortality in 34-35 Weekers?

Send a text In this segment, Ben and Daphna review a retrospective study from the Hospital for Sick Children comparing outcomes of therapeutic hypothermia in late preterm (34-35 weeks) versus early term (36-37 weeks) infants. They discuss the significantly higher rates of mortality, hemodynamic instability, and hypoglycemia found in the younger cohort, known as "Group 1". The hosts explore the implications of using MRI scoring systems like the Weeke score for preterm brains and debate the ethical challenges of conducting future randomized trials as clinical practice shifts away from cooling younger babies based on emerging retrospective data. ---- Whole-body hypothermia in late preterm and early term infants: a retrospective analysis from a neurocritical care unit. Martinez A, Cikman G, Al Kalaf H, Wilson D, Banh B, Abdelmageed W, Beamonte Arango I, Christensen R, Branson HM, Cizmeci MN.Pediatr Res. 2026 Jan 7. doi: 10.1038/s41390-025-04701-x. Online ahead of print.PMID: 41501407 Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

23 hrs ago

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23 min
2025-11-02

#373 - NRP 9th Edition Updates ft Dr. Henry Lee

Send us a text The Incubator Podcast welcomes Dr. Henry Lee, Associate Editor of the Textbook of Neonatal Resuscitation, to discuss the ninth edition of the Neonatal Resuscitation Program (NRP). They review major updates released October 22, 2025, including the extended 60 second delayed cord clamping, new guidance on cord milking, refined oxygen targets, ventilation parameters, and updates to airway management and corrective steps. They also highlight three new educational modules, NRP Cardiac, Resuscitation in the NICU, and Neonatal Education for Prehospital Professionals, emphasizing how these changes support evidence based and effective neonatal care worldwide. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

2025-11-02

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45 min
JAN 16

#393 - [Neo News] - 📌 CDC vs. AAP: What Is the Right Approach to Hep B Vaccination at Birth?

Send us a text This week on Neo News, we tackle the recent and controversial divergence between CDC and AAP guidelines regarding the birth dose of the Hepatitis B vaccine. With the CDC now recommending a deferred schedule for infants of Hepatitis B-negative mothers, we explore the clinical implications, the risks of vertical transmission, and the challenge of navigating discordant public health advice. We discuss how to handle shared decision-making in an era of waning vaccine confidence and why the "birth dose" remains a critical safety net in a community setting. Join us as we break down the data behind the headlines. ---- American Academy of Pediatrics. (2025, December 15). AAP: CDC decision on universal birth dose of hepatitis B vaccine irresponsible and purposely misleading. AAP News. https://publications.aap.org/aapnews/news/33980/AAP-CDC-decision-on-universal-birth-dose-of?searchresult=1?autologincheck=redirected Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Jan 16

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23 min
JAN 21 • SUBSCRIBERS ONLY

#129 - 🤰MFM - Questions: 1, 3, 4, 7

To learn more and have access to show notes and articles mentioned in this episode, go to www.the-incubator.org/review Please subscribe to the podcast for access to daily episodes. If you have any questions feel free to email the show at nicupodcast@gmail.com You can also contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd.

Jan 21

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15 min

Ben and Daphna go through daily neonatal board questions. If you are studying for the upcoming neonatal boards exam or just want to keep your neonatal knowledge sharp, this is the podcast for you. This show is done in collaboration with Neonatology Review (Dr. Dara Brodsky and Dr. Camilia Martin).

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The neonatology focused podcast hosted by Dr. Ben Courchia MD & Dr. Daphna Yasova Barbeau.