A Shot in the Arm Podcast

Ben Plumley

Welcome to A Shot In The Arm Podcast, where we take a deep dive into the heart of global health. Since our launch in 2019, we've released over 150 episodes that illuminate the intersection of innovation and equity in healthcare. Join me, your host Ben Plumley—a global infectious disease strategist and passionate HIV advocate, along with our expert team of co-hosts, as we engage in compelling, character-driven conversations with a diverse array of guests from around the world. Together, we explore the intricate connections between everyday lives and biomedical research, tackling pressing issues like pandemic preparedness, climate disruption, and the impact of conflict. Tune in as we uncover the stories and insights that shape our collective health narrative, making complex topics both entertaining and accessible. Let's embark on this journey to improve lives, one episode at a time!

  1. Redefining Global Health in the 21st Century, Chapter 1: The End of the Old Order – and What Comes Next

    1d ago

    Redefining Global Health in the 21st Century, Chapter 1: The End of the Old Order – and What Comes Next

    A Shot in the Arm Media in partnership with UCSF Institute for Global Health launched a nine-part series to explore the future of global health built around the book Redefining Global Health in the 21st Century, co-authored by Dr. mike Reid (UCSF Institute for Global Health Sciences) and Ambassador Eric Goosby (former U.S. Global AIDS Coordinator and former PEPFAR Chief Medical Officer). In this episode, what if the greatest threat to global health isn't a new virus — it's us? Our funding fatigue, our outdated playbook, our addiction to replication over adaptation. We've saved millions of lives. But are we sleepwalking inexorably into decline, into the enshittocene. Eric and mike don’t think so. And they’ve written a book, “Redefining Global Health in the 21st Century, that sets out an alternative, optimistic future. In this episode, they reflect on the end of the old order, and the implications for innovation and scale up into a new era in global health. mike and Eric are hosted by Ben Plumley from A Shot In The Arm Media. 00:00 Series Kickoff Recap 01:25 Early Wins Foundations 02:07 Global Fund and PEPFAR Tensions 04:40 What Worked Best 06:29 Malawi Dependency Shock 08:48 Why Systems Collapsed 12:50 Donor Ecosystem Incentives 18:30 Designing Better Partnerships 23:25 New Players Multipolar Era 27:21 Philanthropy Promise and Peril 31:44 Limits of Philanthropy 32:24 Gates Foundation Lessons 33:41 Sustainability Commitments 35:56 Country Led Coordination 37:45 Innovation Beyond Tech Fixes 39:28 Private Sector as Resource Motor 42:02 Equity Risks and Guardrails 44:24 Indigenous Knowledge in Trials 48:08 From Pilots to Scale 52:19 Access and Global Rollout Rules 54:34 Paradigm Shift Takeaways 55:25 Episode Wrap and Next Steps Learn more about the book: https://bit.ly/redefining-global-health More from UCSF Institute for Global Health Sciences: https://globalhealthsciences.ucsf.edu Check Out mike Reid’s Substack: https://substack.com/@reimaginingglobalhealth Check Out Ben’s Substack: https://substack.com/@benplumley1 Join the Conversation! What would it take for global health to avoid decline? Share your thoughts in the comments! Subscribe & Stay Updated: Listen on Spotify, Apple Podcasts, or your favorite podcast platform. Watch on YouTube & subscribe for more in-depth global health — and look out for a dedicated sub channel for Redefining Global Health in the 21st Century under A Shot in the Arm’s YouTube home. Redefining Global Health in the 21st Century: The Podcast (Playlist on Youtube) https://youtube.com/playlist?list=PLW7yagTEtywqvW9_bs6heRikREgwS9sE9&si=Tu-NEdwcA9Z-VKLH A Shot in the Arm Podcast Youtube (Main Channel) https://youtube.com/@shotarmpodcast

    58 min
  2. Redefining Global Health in the 21st Century: A New Series on Why Global Health Is at a Crossroads

    Jun 15

    Redefining Global Health in the 21st Century: A New Series on Why Global Health Is at a Crossroads

    A Shot in the Arm Media launches a new nine-part series produced in partnership with the UCSF Institute for Global Health Sciences, built around the book Redefining Global Health in the 21st Century, co-authored by Dr. mike Reid (UCSF Institute for Global Health Sciences) and Ambassador Eric Goosby (former U.S. Global AIDS Coordinator and former PEPFAR Chief Medical Officer). In this prologue episode, Reid and Goosby explain why they wrote the book, what defined the “golden era” of global health since the early 2000s—the Global Fund, PEPFAR, Gavi—and why that progress now feels at risk under the Trump administration's cuts to USAID and PEPFAR. They introduce the book's central metaphor, borrowed from Cory Doctorow's concept of “enshittification,” to ask whether global health institutions are on the brink of decay, and argue that decline is a choice, not a destiny. The conversation previews the arc of the series—covering the old order, governance, financing, climate, technology and AI, and self-care for health workers—and closes with a call for honesty, bipartisanship and accountability, grounded in the legacies of Nelson Mandela and Steve Biko. 00:00 Introduction: Is the Greatest Threat to Global Health... Us? 00:49 Launching the Series: Redefining Global Health in the 21st Century 02:06 Meet the Authors: Dr. Mike Reid and Ambassador Eric Goosby 02:32 Why They Wrote This Book 03:28 Writing Through the Trump Transition 05:28 The Golden Era of Global Health 08:04 Shared Responsibility and Its Roots 10:21 What's Unraveling Now 11:34 Vancouver 1996 and the Roots of the Reckoning 12:18 Honoring Health Workers and Naming the Moral Injury 14:18 What Would Have to Change, Structurally and Politically 17:50 “Enshittification” and the Risk of Global Health Decline 20:30 Kuhn, Paradigm Shifts, and a New Vision for Global Health 22:17 Goosby's 38,000-Foot View: Aligning Need, Access and Governance 25:16 Reid on Financing, Governance, Science and New Tools 28:06 Mapping the Series and the Book's Chapters 32:11 Reform Agenda or Transformation Agenda? 35:19 Letters to My Daughters: Making Global Health Personal 37:31 Why Global Health Matters at Home 41:12 Does the Field Still Reflect Why We Got Into It? 43:18 Bipartisanship, Nelson Mandela and Steve Biko 46:18 Toward a Reckoning: Truth, Reconciliation and Accountability 51:02 “Not on Our Watch” 53:27 Holding the Administration to Account 56:32 The Book, Its Price, and Where to Find It 58:23 Sign-Off and What's Coming in Episode Two Learn more about the book: https://bit.ly/redefining-global-health More from UCSF Institute for Global Health Sciences: https://globalhealthsciences.ucsf.edu Check Out mike Reid’s Substack: https://substack.com/@reimaginingglobalhealth Check Out Ben’s Substack: https://substack.com/@benplumley1 Join the Conversation! What would it take for global health to avoid decline? Share your thoughts in the comments! Subscribe & Stay Updated: Listen on Spotify, Apple Podcasts, or your favorite podcast platform. Watch on YouTube & subscribe for more in-depth global health — and look out for a dedicated sub channel for Redefining Global Health in the 21st Century under A Shot in the Arm’s YouTube home. Redefining Global Health in the 21st Century (Playlist on Youtube) https://bit.ly/rgh-podcast A Shot in the Arm Podcast Youtube (Main Channel) https://youtube.com/@shotarmpodcast

    1h 1m
  3. Jun 4

    Food fight: The Impact of Cancer and Chemo on my Appetite

    Another candid update from Ben Plumley on life with stage four colorectal cancer, focusing on one of the most under appreciated challenges of treatment: the daily battle to eat. Treatment Update — Ben is continuing maintenance chemotherapy and awaiting a PET scan at the end of June. The goal is non-progression — holding the cancer steady — which counts as a win. --- 01:30 - The Food Fight — Ben breaks down why eating has become such a struggle, covering two main culprits: the cancer itself and the side effects of chemotherapy -which damages the digestive tract lining and causes nausea, taste changes, and mouth and jaw pain. 03:37 - Taste Changes Explained — Ben describes the layered impact on his senses: from persistent metallic taste, a sulfuric reaction to eggs and squash, to complete tastelessness , and to brights including orange juice and alpine milk chocolate. 09:29 - Cannabinoids as a Tool — After a referral through Kaiser’s infectious disease department, Ben has incorporated CBD tinctures into his routine. 13:56 - And on a genuinely uplifting note, Ben’s vegetable garden is thriving with fruit and vegetables - a reminder that the garden remains a vital source of calm and energy throughout his journey. Hosted by Ben Plumley | A Shot in the Arm Media | Produced and directed by Erik Espera. Join the Conversation! If you or someone you know is living with cancer, share your experiences and thoughts in the comments! Check Out Ben’s Substack: https://substack.com/@benplumley1 Useful resources: https://fightcolorectalcancer.org https://colontown.org Subscribe & Stay Updated: Listen on Spotify, Apple Podcasts, or your favorite podcast platform. Watch on YouTube & subscribe for more in-depth global health news.

    16 min
  4. Lessons from the Frontlines: San Francisco

    May 10

    Lessons from the Frontlines: San Francisco

    This is the first episode of AIDS 2060, a special multimedia mini-series of podcasts and Substack articles devoted to understanding what is needed to bring the HIV epidemic under control, how long that will take, and why the world has been unable to do so to date, notwithstanding overly ambitious public commitments that questionably are not rooted in science and hide the real threat HIV poses, even today. We are in San Francisco, one of the first epicenters of the epidemic, and meet the City’s Community Health Center which is on the frontline of providing comprehensive care and prevention services to the hardest to reach populations, people of color, the trans community, people who inject drugs, the homeless and people with mental health issues. Ending the HIV epidemic will not be achieved, let alone by an arbitrary date like 2060, unless human rights and evidence-based programs reach and are used by these people. Does a progressive city like San Francisco have the political will to do what the science tells us works? Host Ben Plumley is joined by Lance Toma (CEO), Dan O’Neill (Chief Medical Officer), and Dr. Tatyana Moaton (Chief Strategy & Workforce Officer). 00:00 Welcome to AIDS 2060 00:38 Why the Response Stalled 02:05 Picking 2060 as the Lens 03:01 San Francisco Frontlines 03:39 Targets and Reality Check 04:16 Meet the Health Center Team 05:35 Will AIDS 2030 Happen 07:46 Local Progress and Setbacks 10:52 Who the Clinic Serves 14:12 Trans Communities as Canary 18:15 Surveillance Data Under Attack 22:15 Leading Through Funding Chaos 26:53 Long Acting Injectables in Practice 28:47 Prep Access Gaps and Equity 30:14 Street Medicine and Viral Suppression 32:50 Worrying About Innovation Stalls 33:16 HIV Pipeline Reality Check 33:54 Long Acting Drug Revolution 35:10 New Classes And Regimen Design 36:02 Once Yearly Prevention Vision 37:09 Equity Over Innovation 37:52 Whole Person Care Infrastructure 40:31 Radical Roots And Community Power 42:58 Hard Reboot In Crisis 46:25 Coalitions Beyond HIV 49:43 Data Visibility And Erasure 53:55 Global Community Connections 55:32 2060 Hopes And Closing Check Out Ben’s Substack: https://substack.com/@benplumley1 Join the Conversation! How do you see the future of global health unfolding? Share your thoughts in the comments! Subscribe & Stay Updated: Listen on Spotify, Apple Podcasts, or your favorite podcast platform. Watch on YouTube & subscribe for more in-depth global health.

    1h 4m
  5. Emily Bass on PEPFAR’s Data Spin, What South Africa’s Oral Histories Reveal & the future w/ AIDS2060

    May 6

    Emily Bass on PEPFAR’s Data Spin, What South Africa’s Oral Histories Reveal & the future w/ AIDS2060

    Investigative journalist and public health expert Emily Bass returns to A Shot In The Arm with the most consequential update on the global HIV response in months. Drawing on a brand-new report from Physicians for Human Rights and South African partners — built from 40 oral histories — Emily walks Ben Plumley through the human cost of the Trump administration’s foreign aid disruptions, the staggering waste of dismantled prevention infrastructure, and the bizarre data spin emerging from the State Department. The episode also covers Dr. mike Reed’s headline-making resignation as PEPFAR’s Chief Scientific Officer, the dangerous quiet around supply chain contracts and bed-net procurement, and what the new “America First Global Health Strategy” is choosing to celebrate — and choosing to obscure. Ben closes with a preview of two new initiatives: AIDS 2060, a long-horizon project from A Shot In The Arm Media, and the rebrand of MTV Staying Alive Foundation to Shuga Global. 00:00 Welcome and Setup 01:18 Global Health Upheaval 03:13 PEPFAR Data Spin 04:07 South Africa Report 05:51 Prevention Platform Collapse 09:27 Clinic Breakdown Story 12:52 Why 18 Percent Matters 16:33 Community Resilience 19:22 Research Partnerships Lost 22:12 Treatment Disruptions 25:26 Trauma to Transition 31:11 Data Blackout Returns 39:07 Prep Data Mirage 42:08 Kids Treatment Declines 44:55 Age Data Removed 47:02 Congress Pushback 52:02 Supply Chain Breakdown 59:38 Last Mile Disaster Story 01:02:16 Orderly Transition Demands 01:06:23 AIDS 2060 Vision 01:10:35 Sugar Global Storytelling 01:15:20 Africa Led Future 01:20:42 Closing Thanks Read Emily Bass’ Substack: https://substack.com/@emilysbass Check Out Ben’s Substack: https://substack.com/@benplumley1 Join the Conversation! How do you see the future of global health unfolding? Share your thoughts in the comments! Subscribe & Stay Updated: Listen on Spotify, Apple Podcasts, or your favorite podcast platform. Watch on YouTube & subscribe for more in-depth global health.

    1h 26m
  6. Apr 25

    PEPFAR’s Dr. mike Reid Resigns on Substack: Equity, Authoritarianism, & the Future of Global Health

    Ben Plumley is joined by Ambassador Eric Goosby, and by Dr. mike Reid to react to Reid’s recently announced resignation from PEPFAR on Substack. Reid describes his growing moral dissonance with an administration he characterizes as authoritarian, citing concerns that lifesaving HIV services could be conditioned on geopolitical or commercial interests, a deprioritization of equity, reduced emphasis on evidence-based programming, and rapid changes made without deliberation or stakeholder engagement. The conversation contrasts partnership-based global health diplomacy with short-term coercive quid pro quo dynamics, the push toward country ownership and government-to-government funding, as well as ensuring marginalized populations are still able to access comprehensive HIV services. Is there a need for PEPFAR to course-correct, and if so, how? Perhaps the future will depend on what kind of new administration comes into office in 2029… 00:00 Special Episode Introduction 00:33 Resignation Goes Public 02:53 Why Reid Resigned Now 07:50 Authoritarianism And Ethics 10:39 Quid Pro Quo In MOUs 12:28 Partnership Versus Coercion 15:30 Making Global Health Matter 18:13 Domestic Policy Dissonance 20:22 PEPFAR Not Fit For Purpose 23:56 Country Ownership Fast Track 26:21 Public Health Versus Politics 28:23 Who Gets Left Behind 31:32 Science And Sustainable Transition 33:36 Can PEPFAR Recover 35:54 Shared Blame and Dependency 38:14 MOU Enforcement and Penalties 40:56 Minerals Deals and Ethics 43:37 Lessons From Past Bilaterals 44:47 Building Sustainable Systems 47:45 Doing More With Less 50:50 Efficiency Integration and Tech 52:41 New Tools and Market Shaping 54:08 Personal Next Steps 56:41 Moral Ambition and Hope 01:00:51 Final Thanks and Signoff Read mike’s resignation on Substack: https://reimaginingglobalhealth.substack.com/p/stepping-away Check Out Ben’s Substack: https://substack.com/@benplumley1 Join the Conversation! How do you see the future of global health unfolding? Share your thoughts in the comments! Subscribe & Stay Updated: Listen on Spotify, Apple Podcasts, or your favorite podcast platform. Watch on YouTube & subscribe for more in-depth global health.

    1h 5m

About

Welcome to A Shot In The Arm Podcast, where we take a deep dive into the heart of global health. Since our launch in 2019, we've released over 150 episodes that illuminate the intersection of innovation and equity in healthcare. Join me, your host Ben Plumley—a global infectious disease strategist and passionate HIV advocate, along with our expert team of co-hosts, as we engage in compelling, character-driven conversations with a diverse array of guests from around the world. Together, we explore the intricate connections between everyday lives and biomedical research, tackling pressing issues like pandemic preparedness, climate disruption, and the impact of conflict. Tune in as we uncover the stories and insights that shape our collective health narrative, making complex topics both entertaining and accessible. Let's embark on this journey to improve lives, one episode at a time!

You Might Also Like