The Obesity Doctor Podcast

Dr. Sasha High

Weight, health, and metabolism — without extremes or oversimplification. Hosted by Internal Medicine and Obesity Physician Dr. Sasha High, this podcast explores the biology of weight, the reality of behaviour change, and the nuance often missing from mainstream conversations. From GLP1 medications to emotional eating, from metabolic health to mindset, you'll get practical, evidence-based insights without extremes or oversimplification. This podcast is for those who want to understand their bodies, make sustainable changes, and build health that lasts. FOLLOW Instagram - https://www.instagram.com/sashahighmd/ WORK WITH ME Obesity Medicine Clinic in Ontario, Canada - https://www.highmetabolicclinic.com Best Weight for Women - https://www.sashahighmd.com/bestweight Recover Strong for Binge Eating - https://www.sashahighmd.com/bed

  1. 1d ago

    200.Understanding Your Nutrient Needs: Why Ignoring the Numbers Can Backfire

    In this episode of The Obesity Doctor Podcast, Tedi Glik, Registered Dietitian, breaks down why understanding your nutritional needs can be a powerful tool for supporting your health and weight goals.We'll talk about calories, protein, carbohydrates, and fats, how to estimate your daily energy needs, and why eating too little can sometimes work against you. We'll also explore how to build balanced meals, structure your day, and use food tracking as a tool for awareness rather than restriction.In this episode, we cover:- Understanding your calorie needs (BMR vs. TDEE).- Why eating 1,200 calories isn't necessarily the answer.- How to determine your protein and macronutrient targets.- Building balanced, satisfying meals.- Simple ways to start tracking your food.- Why progress goes beyond the number on the scale.- How to move away from restrictive dieting and build sustainable habits.The takeaway? It's not about eating less or being perfect. It's about understanding what your body needs, nourishing it properly, and finding an approach you can maintain long term.Because knowledge gives you options, and the goal is to build a way of eating that supports your health, muscle mass, energy, and quality of life.RESOURCES:BMR Calculator:https://www.calculator.net/bmr-calculator.htmlWORK WITH US:Dietitian Services:https://www.highmetabolicclinic.com/nutritionO​​ntario-Wide Virtual Obesity Management Clinichttps://www.highmetabolicclinic.comJoin our Weight Loss Coaching Program for women, Best Weight https://www.sashahighmd.com/bestweightRecover Strong for Binge Eatinghttps://www.sashahighmd.com/bedTaking the first step toward weight loss can feel overwhelming — but you don’t have to do it alone. I’ve created a curated list of my podcast episodes to gently guide you as you begin your journey. https://www.sashahighmd.com/podcast-guideFOLLOW SASHAInstagramhttps://www.instagram.com/sashahighmd/

  2. Nov 2

    199. Turning Down the Food Noise: What a New Study Tells us about CagriSema (Part 2 of 2)

    Do you find yourself thinking about food all day, even right after a meal? It’s called food noise, and it is not a character flaw. In part two of my CagriSema series, I walk you through a new study that used appetite testing, questionnaires and brain scans to see how this medication changes appetite, cravings and the brain's response to tempting foods, over a full year.In this episode:- The three systems that control eating, and why food noise happens- How appetite and cravings changed, and why that held at one year- Why eating a bit more at maintenance is a new steady state, not the medication wearing off- The shift away from high-fat, sweet foods- What changed in the brain, from reward to the brain's own "brakes"- Side effects, study limitations, and my clinical pearlsMissed part one? Go back and listen to "Meet CagriSema" first.This episode is for education only and isn't personal medical advice. Please speak with your own healthcare provider.Reference: Abstract presented by Dr. Anthony P. Goldstone at EASD 2026. Effects of CagriSema on appetite, eating behaviour and food cue reactivity using functional MRI in adults with overweight or obesity. (V.F. Uhre et. al.)WORK WITH MEO​​ntario-Wide Virtual Obesity Management Clinichttps://www.highmetabolicclinic.comJoin my Weight Loss Coaching Program for women, Best Weight https://www.sashahighmd.com/bestweightRecover Strong for Binge Eatinghttps://www.sashahighmd.com/bedTaking the first step toward weight loss can feel overwhelming — but you don’t have to do it alone. I’ve created a curated list of my podcast episodes to gently guide you as you begin your journey. https://www.sashahighmd.com/podcast-guideFOLLOW SASHAInstagram - https://www.instagram.com/sashahighmd/

  3. Oct 26

    198. Meet CagriSema: The GLP1-Amylin New Kid on the Block

    The New Kid on the block, coming 2027 (ish?), is CagriSema. Today, I’m giving you a clear, evidence-based introduction.In this episode, I explain what amylin is, why combining it with semaglutide is a new approach, and what the REDEFINE trials actually showed.In this episode:- What amylin is, and how it differs from GLP-1 and GIP- REDEFINE 1: about 20% average weight loss in people without diabetes- REDEFINE 2: results in people living with type 2 diabetes- REDEFINE 4: how CagriSema compared with tirzepatide, and how I interpret it- Side effects, and practical ways to manage them- Where approval stands, and why to avoid unapproved sourcesPart 2, coming next week, goes inside the brain: what CagriSema does to appetite, cravings and food noise.Resources:- Garvey WT et al. Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity (REDEFINE 1). N Engl J Med. 2025.- Davies MJ et al. Cagrilintide–Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes (REDEFINE 2). N Engl J Med. 2025.- Novo Nordisk company announcement on REDEFINE 4, February 23, 2026.This episode is for education only and isn't personal medical advice. Please speak with your own healthcare provider.WORK WITH MEO​​ntario-Wide Virtual Obesity Management Clinichttps://www.highmetabolicclinic.comJoin my Weight Loss Coaching Program for women, Best Weight https://www.sashahighmd.com/bestweightRecover Strong for Binge Eatinghttps://www.sashahighmd.com/bedTaking the first step toward weight loss can feel overwhelming — but you don’t have to do it alone. I’ve created a curated list of my podcast episodes to gently guide you as you begin your journey. https://www.sashahighmd.com/podcast-guideFOLLOW SASHAInstagram - https://www.instagram.com/sashahighmd/

  4. Oct 19

    197. Women’s Mental Health Across Reproductive Transitions: PMDD, Menopause & More with Psychiatrist Dr. Ariel Dalfen

    In this episode, I’m joined by Dr. Ariel Dalfen, a psychiatrist and women’s mental health specialist, to explore the intersection of reproductive hormones, mental health, body image, eating disorders, and metabolic health.We talk about why reproductive transitions—from the menstrual cycle to pregnancy, postpartum, perimenopause and menopause—can be particularly vulnerable times for mental health, and how clinicians can distinguish expected changes from symptoms that warrant treatment.We also discuss:- PMDD: what it is, how it differs from PMS, and why tracking symptoms across the menstrual cycle can be so helpful - Mental health during perimenopause and menopause, including anxiety, depression, sleep disruption and emotional dysregulation - How a history of PMDD, postpartum mental health concerns, or other psychiatric illness may influence risk during the menopause transition - When menopause hormone therapy, psychiatric medication, or a combination may be appropriate - How we should consider weight gain and metabolic health when choosing psychiatric medications -The significant impact of menopause on body image and the risk of eating disorder relapse - The growing pressure around food, exercise, protein, and body composition—and when healthy behaviours can become obsessive - What we know, and what we still don't know, about the relationship between GLP-1 medications and mental health - Why individualized, multidisciplinary care matters so much in women's mental health Most importantly, we talk about the importance of listening to women, taking their symptoms seriously, and looking at the whole person rather than reducing complex experiences to either "just hormones" or a psychiatric diagnosis. Dr. Dalfen is the CEO and co-founder of BRIA, a virtual women's mental health and hormone clinic. She is also an Assistant Professor of Psychiatry at the University of Toronto and previously led the perinatal mental health program at Mount Sinai Hospital in Toronto. Learn more about BRIA at betterbria.com and BRIA Academy at briaacademy.com.Follow BRIA on instagram: @bria.health

  5. Oct 12

    196. The Weekend Trap: Why Your Weekends Are Sabotaging Your Weight Loss

    Why does staying on track with weight loss often feel so much easier during the week, only to become more challenging once Friday afternoon rolls around?In this episode, Tedi Glik, RD will break down what the “weekend effect” is, and how the way we approach food from Friday through Sunday can influence overall weight-loss progress. With more social events, meals out, brunches, alcohol, and time with family and friends, the weekend naturally looks different—but that doesn’t mean it needs to become a completely different eating pattern.We will talk about planning for indulgences rather than thinking in terms of “cheat meals.” The goal isn’t to eliminate the foods you enjoy, but to be more intentional about which foods and experiences are actually worth it to you. Whether that’s a favorite dessert, a croissant, or a glass of wine with friends, there’s a way to incorporate enjoyable foods while still building meals that are satisfying and supportive of your goals.We will also explore some of the thoughts that can drive weekend eating, including “I’ve been good all week, so I deserve to enjoy myself,” “I don’t want to think about food on the weekend,” and “I’ll just start again on Monday.” Sometimes the biggest shift isn’t changing what we eat, but changing the way we think about the weekend. Planning doesn’t have to mean restriction—it can actually create more freedom by reducing the number of food decisions you have to make.Ultimately, you don’t need to choose between losing weight and enjoying your life. The goal is to learn how to do both, and make your weekend part of the plan!MEDICAL PROGRAM FOR OBESITYO​​ntario-Wide Virtual Obesity Management Clinichttps://www.highmetabolicclinic.comJoin my Health & Consistency Coaching Program for women, Best Weight https://www.sashahighmd.com/bestweightRecover Strong for Binge Eatinghttps://www.sashahighmd.com/bedTaking the first step toward weight loss can feel overwhelming — but you don’t have to do it alone. I’ve created a curated list of my podcast episodes to gently guide you as you begin your journey. https://www.sashahighmd.com/podcast-guideFOLLOW SASHAInstagramhttps://www.instagram.com/sashahighmd/

  6. Oct 5

    195. GLP-1 Maintenance: What Do We Actually Know?

    What happens after you’ve lost the weight you wanted to lose?In this episode, I’m looking at what we actually know about maintaining weight loss with GLP-1–based medications. The evidence so far suggests that for most people, continuing treatment at the dose that produced their weight loss provides the best chance of maintaining that weight loss and its associated health benefits.But what if staying on the same dose isn’t possible because of side effects, cost, access, or personal preference?I break down what we’re learning from SURMOUNT-MAINTAIN and ATTAIN-MAINTAIN, including evidence that reducing tirzepatide to a lower dose or switching from injectable semaglutide or tirzepatide to oral orforglipron can preserve substantially more of the weight loss achieved than stopping treatment altogether.We still have important questions about tapering, extending dosing intervals, and whether some people can eventually come off treatment successfully. But for now, the evidence suggests that if we need to reduce treatment intensity, maintaining some active treatment may be a much better strategy than simply stopping and waiting to see what happens.Ultimately, maintenance is about finding the level of treatment that allows an individual to maintain the health benefits they’ve achieved—while recognizing that for many people with chronic obesity, ongoing treatment at their effective dose will be necessary.MEDICAL PROGRAM FOR OBESITYO​​ntario-Wide Virtual Obesity Management Clinichttps://www.highmetabolicclinic.comJoin my Health & Consistency Coaching Program for women, Best Weight https://www.sashahighmd.com/bestweightRecover Strong for Binge Eatinghttps://www.sashahighmd.com/bedTaking the first step toward weight loss can feel overwhelming — but you don’t have to do it alone. I’ve created a curated list of my podcast episodes to gently guide you as you begin your journey.https://www.sashahighmd.com/podcast-guideFOLLOW SASHAInstagram - https://www.instagram.com/sashahighmd/

  7. Sep 21

    193. Understanding Facial Changes After GLP-1 Weight Loss with Dermatologist Dr. Kucy Pon

    Significant weight loss can be life-changing for your health—but it can also lead to changes in facial volume, skin laxity, and the way we see ourselves in the mirror. In this episode, I’m joined by dermatologist Dr. Kucy Pon to unpack what happens to the face after significant weight loss, including weight loss associated with GLP-1 medications. We discuss why these changes are a result of weight loss itself—not a toxicity of the medication—and why age, genetics, skin quality, and the speed and amount of weight loss can all play a role. We also explore what can be done to support skin quality and facial volume, including skincare, nutrition and resistance training, as well as aesthetic options such as hyaluronic acid fillers and biostimulators like Sculptra® and Restylane®. As part of today’s episode, we also discuss Sculpt and Lift by Sculptra® and Restylane®, and how these treatments may be used as complementary approaches to address different aspects of facial volume loss and skin quality. Most importantly, we talk about the importance of individualized assessment, realistic expectations, choosing an experienced, medically trained injector, and remembering that aesthetic treatment is entirely optional. My biggest takeaway: improving your health and wanting to feel good about how you look are not competing priorities. We pursue obesity treatment for health and longevity, but it’s completely okay to want your outward appearance to reflect how vibrant and healthy you feel inside. Please speak with your trusted injector to discuss Sculptra and Restylane’s safety profiles. Learn more at galdermaaesthetics.com/ca or @aestheticsbygalderma.ca Sculptra® Canadian Instructions for Use July 2022. Restylane® LyftTM Canadian Instructions for Use February 2024 Thank you to Galderma for sponsoring this episode.

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About

Weight, health, and metabolism — without extremes or oversimplification. Hosted by Internal Medicine and Obesity Physician Dr. Sasha High, this podcast explores the biology of weight, the reality of behaviour change, and the nuance often missing from mainstream conversations. From GLP1 medications to emotional eating, from metabolic health to mindset, you'll get practical, evidence-based insights without extremes or oversimplification. This podcast is for those who want to understand their bodies, make sustainable changes, and build health that lasts. FOLLOW Instagram - https://www.instagram.com/sashahighmd/ WORK WITH ME Obesity Medicine Clinic in Ontario, Canada - https://www.highmetabolicclinic.com Best Weight for Women - https://www.sashahighmd.com/bestweight Recover Strong for Binge Eating - https://www.sashahighmd.com/bed

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