LONGEVITY with Nathalie Niddam Nathalie Niddam

Have you ever sifted through a mountain of health advice only to feel more lost than when you started? 
 
That's where Dr. Elizabeth Yurth comes in—guiding us through aging research with her knowledgeable insights. In today’s episode, we discuss anti-aging medicine, the pitfalls of research bias, and the gender discrepancies that muddy the waters of scientific studies. 
With a nod to John Ioannidis' work, we talk about the need for validating scientific claims. When theory meets practice, the truth can be surprising. We share firsthand experiences from clinical work, revealing how animal studies fare once they reach the human testing ground. 
 
Overall, we explore the heart of longevity, where social connections and stress-free living are crucial. 
 
Dr. Elizabeth Yurth is the Co-Founder and Chief Medical Officer of Boulder Longevity Institute, where she has been providing Tomorrow’s Medicine Today to her clients since 2006. Dr. Yurth has completed over 500 hours of Continuing Medical Education (CME) training in the areas of Longevity, Epigenetics, Nutrition, Bioidentical Hormone Replacement Therapy, Regenerative Peptide Treatments, and Regenerative Orthopedic Procedures. 



Thank you to our sponsors for making this episode possible:
Quicksilver: Visit quicksilverscientific.com/nat and use code Nat for 10% off your first purchase of PushCatch® Liver Detox.
BiOptimizers: For Sleep Breakthrough use code bionat at checkout to save on your order at bioptimizers.com/bionat
 
Find more from Dr. Elizabeth Yurth: 
Website: https://boulderlongevity.com/ 
Instagram: @boulderlongevityinstitute
Youtube: https://www.youtube.com/@boulderlongevityinstitutel5018 
 
Find more from Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ 
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community 
Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0 
Instagram: https://www.instagram.com/nathalieniddam/ 
Website: www.NatNiddam.com   
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance 



What We Discuss: 
(00:02) Navigating Aging Research and Recommendations
(07:22) Clinical Testing Ground for Longevity Drugs
(20:05) Benefits and Risks of Antioxidants
(31:42) Cycling Supplements and Aging Measurements
(35:47) Reevaluating Biological Aging and Longevity
(45:03) Low-Dose Naltrexone for Repurposed Medication
(54:56) Drug Repurposing for Various Health Conditions
(01:00:33) Weight Loss Drugs and Their Effects
(01:11:24) Cellular Health and Longevity Discussion



Key Takeaways:
Research findings should be critically evaluated, considering factors such as study design, reproducibility, and applicability to humans.
LDN can be effective in reducing cramps and arthritis symptoms by deactivating microglial cells.
Amlexanox is an underutilized drug with anti-allergic and anti-inflammatory properties.
Tessafensin, a triple uptake inhibitor, may aid in weight loss and improve cellular function.
 

When you think of creatine, what comes to mind? If you're like most people, you probably associate it with building muscle and enhancing athletic performance. But did you know that creatine has benefits that go far beyond the gym?
 
In today's podcast episode, I dive into the fascinating world of creatine and discuss its incredible potential for supporting brain health, bone density, and even protecting your DNA from damage. That's right – creatine isn't just for athletes anymore!
 
To get the full scoop on how this simple compound can help you optimize your health and potentially slow down the aging process, I encourage you to tune in. In just 30 minutes, you'll gain a wealth of knowledge about creatine and how to incorporate it into your daily routine for maximum benefits.



Thank you to our sponsors for making this episode possible:
LVLUP: Use code NAT10 to save 10% off at https://lvluphealth.com/
 
Find more from Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community
Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0
Instagram: https://www.instagram.com/nathalieniddam/
Website: NatNiddam.com
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance
 
What I discuss:
2:24 How to supplement with creatine 
4:47 How creatine works in the mitochondria  
7:11 Creatine's benefits for muscle, including satellite cell activation and heat tolerance 
9:34 Creatine's benefits for bone health and remodeling  
11:59 Creatine's neuroprotective effects and cognitive benefits, especially for older adults  
14:25 Creatine's potential benefits for depression, diabetes, and cardiac insufficiency  
16:24 Creatine's role in protecting mitochondrial DNA from damage  
21:00 Concerns about creatine supplementation, including kidney health, hair loss, and cancer 
25:43 Recommendations for creatine supplements and how to incorporate them into your routine  



Key Takeaways:
Creatine has wide-ranging benefits beyond athletic performance, including muscle, bone, brain, DNA protection, diabetes, heart health, and skin.
Supplementation guidelines for creatine include dosing, timing, and potential concerns for kidney health, hair loss, and cancer.
Creatine may have positive effects on various health conditions, but individuals should consult with their healthcare provider before starting supplementation.

Are you tired of yo-yo dieting and struggling to achieve lasting weight loss? Have you heard about the buzz surrounding GLP-1 agonist medications like semaglutide and tirzepatide but aren't sure how to effectively incorporate them into your journey? 
 
In today’s episode, Dr. Gus Vickery and I discuss the effective use of GLP-1 agonist medications like semaglutide and tirzepatide for sustainable weight loss. He emphasizes the need for a mindset shift, viewing these drugs as powerful tools to catalyze positive changes rather than easy fixes or crutches. Dr. Vickery explains that these medications provide leverage to implement foundational healthy habits and that the key to success lies in focusing on nutrient sufficiency, not just calorie restriction.
 
We also discuss concerns surrounding GLP-1 medications, such as the potential for muscle loss and the risk of regaining weight after discontinuing the drugs. He shares strategies to mitigate these issues, including resistance training, adequate protein intake, and gradual dose reduction when nearing one's goal weight.
 
Dr. Gus Vickery is an author, speaker, and the founder and directing physician of Authentic Health in Asheville, North Carolina. He established his practice with a commitment to delivering holistic, compassionate, and evidence-based care.
 
Thank you to our sponsors for making this episode possible:
Quicksilver: Visit quicksilverscientific.com/nat and use code Nat for 10% off your first purchase of PushCatch® Liver Detox.
Neurohacker Collective: Visit neurohacker.com/nathalie and use code NATHALIE
Inside Tracker: Use NIDDAM to save 10% at https://www.insidetracker.com
 
Find more from Dr. Gus Vickery: 
Website: https://drgusvickery.com/ 
Authentic Health Book: https://drgusvickery.com/book/ 
Instagram: @drgusvickerymd 
Youtube: The Family Doctor



Find more from Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ 
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community 
Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0 
Instagram: https://www.instagram.com/nathalieniddam/ 
Website: www.NatNiddam.com   
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance 



What We Discuss: 
04:00 Understanding the Power of Peptides
07:45 The Underlying Benefits of Peptides
12:59 Addressing Concerns about Side Effects
29:06 The Right Way to Use Peptides
30:06 Hormone Therapy and Peptides
34:12 Nutrient Sufficiency and Protein
41:17 The Impact of Fasting and Gut Health
45:33 Addressing Microbiome Balance
58:56 The Pace of Fat Loss and Patience
59:42 Pushing Through Plateaus and Delicate Nervous System
01:07:13 Managing Hormetic Stress and Resting the Nervous System
01:09:00 Choosing Carbs or Fats and Individualization
 
Key Takeaways:
Peptides can be a powerful tool for improving body composition and metabolic health.
It is important to understand the proper use of peptides and not rely on them as a quick fix or easy way out.
Peptides have a range of benefits, including improving insulin sensitivity and reducing fatty liver disease.
Concerns about side effects and risks should be weighed against the potential benefits and individual circumstances
 

Have you ever wondered why some people seem to bounce back from stress more easily than others? The answer may lie in the strength of their vagus nerve.
 
In today’s episode of the Longevity Podcast, I chat with Dr. Navaz Habib about the importance of the vagus nerve and its impact on heart rate variability (HRV). He explains that the vagus nerve is a unique nerve that connects the brain to all organs in the thorax and abdomen, allowing for communication and signaling. Vagal tone, which refers to the strength of the signals sent through the vagus nerve, is crucial for optimal health. 
 
Dr. Habib identifies four types of stressors that can affect vagal tone: emotional, physical, biochemical, and psychological. He emphasizes the importance of proper breathing techniques, such as slow, diaphragmatic breathing, to improve vagal tone. We also discuss the role of nitric oxide in supporting vagus nerve function and how to supplement it for overall health. 
 
Dr. Navaz Habib, is a Doctor of Chiropractic and Functional Medicine Practitioner who empowers his clients to dig deeper and find the answers to what is holding back their health, affecting their energy and productivity. He is also the host of The Health Upgrade Podcast and speaks on various topics related to Vagus Nerve and its impact on optimal health.
 
Thank you to our sponsors for making this episode possible:
Fatty15: Visit http://fatty15.com/NAT  and use promo code NAT to save.
Mitopure: Use code NAT10 for 10% your order at https://www.timelinenutrition.com/shop/nutrition 
Berkeley Life: Consumers may register and place an order using my code NIDDBL for 10% off at berkeleylife.com 
 
Find more from Dr. Navaz Habib:
Website: https://drnavazhabib.kartra.com/page/DrHabibHome 
Instagram: @drnavazhabib
Book: Upgrade Your Vagas Nerve
Podcast: The Health Upgrade Podcast
 
Find more from Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ 
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community 
Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0 
Instagram: https://www.instagram.com/nathalieniddam/ 
Website: www.NatNiddam.com   
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance 



What We Discuss: 
00:00 Introduction and Importance of the Vagus Nerve
15:21 Understanding Vagal Tone and Its Importance
28:42 Heart Rate Variability and Its Significance
31:27 Using HRV as a Future-Focused Tool
36:02 The Connection Between Nitric Oxide and the Vagus Nerve
45:45 Breathwork and Dietary Support for Vagal Tone
51:07 Electrical Vagus Nerve Stimulation for Vagal Function
 
Key Takeaways:
The vagus nerve is a unique nerve that connects the brain to all organs in the thorax and abdomen, allowing for communication and signaling.
To improve vagal tone and support the vagus nerve, practice breathwork techniques such as diaphragmatic breathing and longer exhales.
Consider nitric oxide supplementation and maintain electrolyte balance to enhance vagal tone.
 

Do you want to optimize fat loss, hormone health, and/or bone strength? You should know that muscle is your secret weapon. 
 
In today’s episode of the Longevity Podcast, I talk with Eric Fete, DO about the intricate relationship between muscle and bone health, and how strength training, proper nutrition, and supplements can help maintain and improve both. We also explore the importance of muscle as a powerful energy factory due to its high concentration of mitochondria, and how staying active can help reclaim your energy levels. Dr Eric and I touch on the crucial role of testosterone in women's health, and how lifting heavy can support this hormone, leading to improved insulin sensitivity, muscle mass, blood pressure, mood, and a reduced risk of cancer.
 
Lastly, we address concerns about fat loss peptides potentially causing muscle mass loss. We emphasize that proper nutrition and strength training can help negate these effects, ensuring that weight loss comes primarily from body fat. 
 
Dr. Eric Fete, DO is the founder of PrimeX, a preventive health, age management, and peak performance company that provides nutrition products, educational materials, physician-grade supplements, hormone therapy, and personalized health plans for maximum health, vitality, performance, and wellness. 
 
Thank you to our sponsors for making this episode possible:
Mitopure: Use code NAT10 for 10% your order at https://www.timelinenutrition.com/shop/nutrition
Quicksilver: Visit quicksilverscientific.com/nat and use code Nat for 10% off your first purchase of PushCatch® Liver Detox.
BiOptimizers: For Sleep Breakthrough use code bionat at checkout to save on your order at bioptimizers.com/bionat



Find more from Eric Fete, DO:
Website: www.drericprimex.com, www.primexweightloss.com
Instagram: https://www.instagram.com/drericfete/ 
Youtube: https://www.youtube.com/@dr.eric-primexthefitnessph6601 



Find more from Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ 
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community 
Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0 
Instagram: https://www.instagram.com/nathalieniddam/ 
Website: www.NatNiddam.com   
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance 



What We Discuss: 
1:30 Muscle Medicine vs Sick Medicine with Eric Fete, DO
7:30 The relationship between muscle and bone
12:50 Vibration plates 
25:00 How muscle affects metabolism
31:00 Testosterone for women and estrogen for men
42:50 GLP-1s and building muscle 
54:55 Supplements for people who don’t want GLP-1s
 
Key Takeaways:
Muscles secret myokines which directly build bone and make it stronger. Myokines exert a stimulative effect and prevent bone reabsorption (breaking down and weakening). Proper nutrition, strength training, and supplements can mitigate bone deterioration.
Muscle is one of the most powerful energy factories because it’s full of mitochondria. You can reclaim your energy by being active. 
Fat loss peptides can possibly make you lose muscle mass, but proper nutrition and strength training can negate those effects so you lose mainly body fat. You could also balance it out by using other peptides like growth hormone.
 

How can our mindset, emotions, and life experiences impact our physical health and immune function in ways that are often overlooked by conventional medicine?
 
We’re diving right into this topic for today’s conversation. Dr. Olivia Lesslar joins the podcast to discuss the field of psycho neuro immunology (PNI) and its impact on health and well-being. She explains the complexity of PNI and how everything in the body is interconnected. Dr. Lesslar emphasizes the power of belief and mindset in influencing health outcomes and highlights the importance of addressing emotions and attitudes in patient care. 
 
We also discuss the role of compassion in medicine and the need to treat the whole person. Our conversation explores the subjectivity of pain, the impact of hypochondria and the nocebo effect, and the potential for small changes to make a significant difference in health. 
 
Dr Olivia works with innovative clinics and organizations worldwide. Her coordinating clinic is Cingulum Health - a neuro center founded by renowned neurosurgeon Professor Charles Teo.  
She is an Adjunct Senior Lecturer with The National Centre for Neuroimmunology and Emerging Diseases.
 
Thank you to our sponsors for making this episode possible:
Neurohacker Collective: Visit neurohacker.com/nathalie and use code NATHALIE
Fatty15: Visit http://fatty15.com/NAT and use promo code NAT to save.
Inside Tracker: Use NIDDAM to save 10% at https://www.insidetracker.com
 
Find more from Olivia Lesslar:
Website: https://www.drolivialesslar.com/ 
Instagram: https://www.instagram.com/drolivialesslar/ 
Facebook: https://www.facebook.com/drolivialesslar 



Find more from Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ 
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community 
Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0 
Instagram: https://www.instagram.com/nathalieniddam/ 
Website: www.NatNiddam.com   
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance 



What We Discuss: 
02:13 Psycho Neuro Immunology (PNI)
03:35 The Complexity of PNI
06:16 The Power of Belief and Mindset
10:47 Anxiety and the Importance of Letting Go
17:15 Navigating Hypochondria and Nocebo Effect
20:50 The Power of Small Changes
26:09 The Role of Transient Receptor Potential Ion Channels
39:02 Immunotherapy and Emotions
40:20 The Impact of Stress on Allergies
41:57 The Neglect of Lifestyle Changes in Medicine
50:42 Curiosity and Open-Mindedness in Medicine
53:23 Reframing Threats and Flooding the Body with Safety Signals
01:02:43 The Biology of Belief and Curiosity




Key Takeaways:
Psycho neuro immunology (PNI) is a field that explores the interconnectedness of psychology, the nervous system, the immune system, and hormones.
Belief and mindset have a significant impact on health outcomes and can influence the body's physiological responses.
Emotions and attitudes play a crucial role in overall well-being and should be addressed in patient care.