“What we now consider modern diagnosis, and the literary genre of detective fiction, arose around the same time and mutually influenced each other. We cannot understand the way we do diagnosis today without tracing this prehistory.” — Dr. Lakshmi Krishnan Today, on “The Things Not Named,” I speak with Dr. Lakshmi Krishnan, physician, scholar, and director of medical humanities at Georgetown University, on why diagnosis and detective fiction grew up together, and what doctors and patients lose when humanities is stripped from medical education. Below is an edited transcript of our conversation on Substack Live. Transcript: Joshua Doležal: Welcome back to The Things Not Named. I’m Joshua Doležal, and my series this year is based on a famous phrase from Willa Cather, who said that it’s the presence of the thing not named that gives high quality to literature. So this year I’m asking that question of medicine. How might we all be more attentive to what goes unsaid in the clinic, in popular culture, and in the experience of illness from the patient’s side? My guest today is Dr. Lakshmi Krishnan, and she’s the first in the series to talk about teaching, so that’s going to be a real treat. Lakshmi is an assistant professor of medicine and director of medical humanities at Georgetown University. Her work spans history of medicine, literary studies, and clinical research. She writes about how doctors know, how they think they know, and what impact those stories have on patients’ diagnosis and research. Her scholarship appears in journals such as JAMA, The Lancet, and BMJ Medical Humanities. She’s also been featured in STAT News, The History Channel, and Voice of America. She publishes The Workup with Dr. Lakshmi Krishnan, a Substack on medicine and culture, and is writing a book for Johns Hopkins University Press, which we’ll definitely talk about, titled The Doctor and the Detective: A Cultural History of Diagnosis. Lakshmi was born in Bombay, India, and is a proud immigrant. Her childhood was spent in England and most of her young adulthood in the southern United States, quite a few different regions there, and she adores all things theater, swimming, curating playlists, and weekly trips to the DC Public Library. So welcome, Lakshmi. Lakshmi Krishnan: Thanks so much for having me. This is great. Joshua Doležal: I can’t wait to dig into all of this. I’m fascinated by all of your personal interests, but I wanted to start with your origin story. So fascinating. I grew up in Montana, went to college in Tennessee in the South, did my graduate work in the Midwest, in Nebraska. I spent some time in South America. I’ve also been to Prague a few times. So I don’t know that I’ve been shaped by all those places quite the same way as you, because these were formative years for you. But I’d like to know more about your story. You’re from Mumbai originally, but you grew up in the UK and the southern US. So how have each of those places contributed to who you are now and how you think today? Lakshmi Krishnan: I think it’s interesting, because at first glance, these are places that don’t necessarily have much in common. So yes, I was born in Bombay, now Mumbai, but I still have the pre-90s, very colonial name in my head. But that was really formative. I was born there and was raised for a good chunk of my young childhood, and then actually went back to part of elementary school there in a joint family. So there’s a lot of storytelling. There’s a lot of trading health stories. That’s very much in our culture. I think the things that you observe when you’re a small child and are embedded in are at work often subconsciously. But I still have very strong memories of our family doctor who paid house calls and would come over with this beaten-up leather bag, and lived down the way in this particular neighborhood in Bombay. He was very much a local character, very much a pillar of that neighborhood. He’d come over and do all the checkups, like the young kids — it was a joint family, so cousins, aunts and uncles, parents, then the grandparents. The grandparent visits usually took longer because they had more things going on in terms of health conditions, and he would get plied with cups of tea. I just remember the storytelling that was such a big part of that. And then we moved to the UK and lived in four or five different places in the span of about four years. So even within the UK, broad regional variation, like London to Salford, which is just outside of Manchester, in the north, and then back down to Nottingham, which is in the south of the country, or kind of the Midlands, I suppose. And when you’re the kid who’s always new in school, who’s always finding their footing, I think that part of my experience was very lonely in a lot of ways. I was an only child at the time. My sister was born later, so I’m no longer an only child. But books were a huge — they were a constant and an anchor. And so I think that kind of reading habit, and reading as a source of solace and comfort, and knowing that I wasn’t the only person who had been an outsider in different places, was really big. And then we moved to the US, and we moved to East Tennessee, actually, which was new again. So I guess, as such retrospective narratives go, if I have to assign some coherence to this — my interest was always in connecting across these experiences, even if on a surface level they seemed, southern England to the southern United States to a huge, densely populated city in India. Finding points of connection and commonality was, I think, very important for my internal coherence as a person. And I guess that translated in some way to the work that I do, or to the paths that I followed. Things that seem on the surface disconnected might not be, and you might actually find really surprising connections. So yeah. I could go on, but I’ll stop there. Joshua Doležal: I went to college in Tennessee, in East Tennessee actually. So I’m curious — I was in Bristol, the birthplace of country music. In fact, not Nashville, but Bristol. And so I had a crash course in barbecue and NASCAR and all kinds of things there. But where were you? Lakshmi Krishnan: Johnson City. Joshua Doležal: Johnson City. Wow. Pretty close. What years? Lakshmi Krishnan: We were there from 1995 to — my folks moved to North Carolina in 2021, so a significant — I mean, I went to middle school and high school in Johnson City. Then I left. I went to North Carolina for college. But that was, and is still, home in a lot of ways. Joshua Doležal: How interesting. I’m sure much older than you. I was in college there at that time. I started college in ‘94 and graduated in ‘97, so we overlapped, very close proximity, for two years without knowing. So interesting. I don’t know if you believe in coincidences, or plans, but that’s pretty remarkable. Lakshmi Krishnan: So interesting. The Tri-Cities. Joshua Doležal: Yeah. I played baseball there, and in those days funding for athletics was a different thing, especially at a small school. So we did fundraisers like go clean the NASCAR raceway after the Bristol 500. Lots of character-building experiences like that. So, Lakshmi, you have an MD and a PhD in English, which is kind of an unusual combination. So I want to talk about those two degrees. I’m sure you had lots of people telling you not to get the PhD in English. Maybe I’m wrong about that. But one of them is the degree that everyone pushes for down the STEM path, right? Go be a doctor. The PhD in English is the one that everybody’s like, well, what can you do with that? It’s not practical. So when did you know you wanted both? And what was the through line that connected them for you? And am I right or wrong that people questioned the second one? Lakshmi Krishnan: You’re absolutely right that people questioned the second one. I’ll answer the first question first. So it was kind of an odd and winding road. In undergrad, I was an English major and I was pre-med. I went to Wake Forest for college, and it was a very liberal-arts-heavy curriculum, which was wonderful. We had divisional requirements — you had to take philosophy, some kind of theology, you had to take a couple of lit classes. That kind of didn’t matter to me, because I was interested in those courses anyway and would have taken them anyway, but it was nice to have it as part of the structure. But at that time, majoring in a humanities field and being pre-med was very atypical. I think then, as now, there have been critical mentors or teachers or professors who’ve been supportive and who’ve believed in this nontraditional curriculum, this nontraditional path for me. And that was the case at Wake. I had a few English professors who either were very interested in STEM or were medical humanists, and I didn’t even have the language to articulate that at the time. They were sort of like, you can do both of these things. If you’re interested in them, you might have to take extra — you might be on an overload a couple of semesters because of organic chemistry lab or things like that. But generally, I felt like I was well supported. It was really post-undergraduate that I got more pushback. So the plan had been to go to medical school. I didn’t really know how to make sense of a PhD in English plus medical school. But really, it came down to funding, which is the frank and blunt answer. I got a scholarship to go to England to get a master’s. And at that time I was like, I could get a master’s in a STEM field, but I’m going to be doing that in medical school. I’m going to be doing the science thing. I love literature. When will I again have this opportunity? So for me it was — maybe my scarcity mindset was helpful, because I was like, I’ll never again get the chance to be funded to do this work. So I did the master’s, and