Tripsitter Podcast

Tripsitter

Welcome to the Tripsitter Podcast, where we unravel the science and stigma of drugs, mental health, addiction, and consciousness. Join us as we converse with experts in psychedelics, harm reduction, and the battle against prohibition. There’s no such thing as a good or bad drug — they’re just chemicals. Whether natural or unnatural, it’s our relationship with the that can be either good or bad. Listen on Spotify, Apple Podcasts, or search for us wherever you get your podcasts. Subscribe to tripsitter.substack.com to get more exclusive content as it drops. Episodes every second Thursday.

  1. #20: The Evolution of Psychedelic Mushrooms with Dr. Jason Slot

    2024-05-31

    #20: The Evolution of Psychedelic Mushrooms with Dr. Jason Slot

    Join us as we dive into the hidden world of psychedelic fungi — uncovering the evolution of psilocybin, the science behind its effects, & the surprising discovery of gene sharing among fungi. Topics Discussed: Mushroom cultivation, evolution of psychedelic fungi, horizontal gene transfer, academic mycology programs, stoned ape hypothesis, the ecological role of psychedelic fungi, and more. Justin, Ro, and James sit down with Dr. Jason Slot, Associate Professor of Fungal Evolutionary Genomics at The Ohio State University. Dr. Slot is affiliated with the Center for Psychedelic Drug Research and Education and the Entheome Foundation. He coordinates the mycology minor at Ohio State and has made groundbreaking discoveries in the evolution of psilocybin-producing fungi. In this episode, we explore the origins and ecological roles of psilocybin, the phenomenon of horizontal gene transfer, and the hurdles faced by researchers due to regulatory constraints. Dr. Slot's insights provide a deeper understanding of the mysterious and complex world of psychedelic fungi. Follow Tripsitter on Substack, Twitter, Bluesky, Spotify, or Instagram for more. Follow Jason on Twitter. Articles by Dr. Jason Slot Horizontal gene cluster transfer increased hallucinogenic mushroom diversity (2018) Psychedemia: Charting the future of interdisciplinary Psychedelic Studies (2023) Domestication through clandestine cultivation constrained genetic diversity in magic mushrooms relative to naturalized populations (2023) The evolution and ecology of psilocybin in nature (2023) Genome sequencing progenies of magic mushrooms (Psilocybe subaeruginosa) identifies tetrapolar mating and gene duplications in the psilocybin pathway (2023) Plant-fungal mutualisms (2022) Reconstructing the early evolution of Fungi using a six-gene phylogeny (2006) The Paleozoic Origin of Enzymatic Lignin Decomposition Reconstructed from 31 Fungal Genomes (2012) The Evolution of Fungal Metabolic Pathways (2014) → See More

    1h 35m
  2. #19: Psychedelic Safeguards with Jules Evans

    2024-04-29

    #19: Psychedelic Safeguards with Jules Evans

    Topics Discussed: Challenging psychedelic experiences, derealization/depersonalization, ecstatic experiences, bad trips, acid flashbacks, HPPD, & the value of integrated support after taking psychedelics. Justin and James sit down with Jules Evans to discuss harm reduction and ethics in the field of psychedelics. Jules is the director of The Challenging Psychedelic Experiences Project and editor-in-chief of Ecstatic Integration — a Substack publication dedicated to making psychedelic culture safer by improving the ecstatic literacy of Western cultures. Jules is also the author of several books, including Philosophy for Life and Other Difficult Situations, The Art of Losing Control, Holiday From The Self: An Accidental Ayahuasca Adventure, and Breaking Open: Finding a Way Through Spiritual Emergency (co-authored with Tim Read). Follow Tripsitter on Substack, Twitter, Bluesky, Spotify, or Instagram for more. Follow Jules Evans on Twitter & read his work on Ecstatic Integration, Philosophy For Life, and YouTube. Must-Read Articles & Books By Jules Evans How Philosophy Can Save Your Life (TedX Talk) Philosophy for Life and Other Difficult Situations (📚) The Art of Losing Control (📚) Holiday From The Self: An Accidental Ayahuasca Adventure (📚) Breaking Open: Finding a Way Through Spiritual Emergency (📚) The Psychedelic Industry's Entity Dilemma (Ecstatic Integration) 3 Ways to Build a Psychedelic Safety Net (Ecstatic Integration) Synthesis and the Shadow of Psychedelic Capitalism (Ecstatic Integration) Coming Back Together: A Qualitative Survey Study of Coping and Support Strategies Used by People to Cope With Extended Difficulties After the Use of Psychedelic Drugs (2024) ‘More evolved than you’: Evolutionary spirituality as a cultural frame for psychedelic experiences (2023) Psychedelic integration challenges: Participant experiences after a psilocybin truffle retreat in the Netherlands (2023) Extended Difficulties Following the Use of Psychedelic Drugs: A Mixed Methods Study (2023)

    51 min

About

Welcome to the Tripsitter Podcast, where we unravel the science and stigma of drugs, mental health, addiction, and consciousness. Join us as we converse with experts in psychedelics, harm reduction, and the battle against prohibition. There’s no such thing as a good or bad drug — they’re just chemicals. Whether natural or unnatural, it’s our relationship with the that can be either good or bad. Listen on Spotify, Apple Podcasts, or search for us wherever you get your podcasts. Subscribe to tripsitter.substack.com to get more exclusive content as it drops. Episodes every second Thursday.