The Incubator

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vor 3 Tagen
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Monatlich
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14. Mai
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26. Juni
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Zweiwöchentlich

20.08.2024

#233 - (NEW) What you need to know about the Neonatal Kidney (ft Dr. Askenazi and Dr. Beck)

Send us Fan Mail In this episode of The Incubator podcast, hosts Ben Courchia and Daphna Barbeau welcome Dr. David Askenazi and Dr. Tara Beck to discuss neonatal nephrology. The conversation explores the challenges of defining and diagnosing acute kidney injury (AKI) in newborns, highlighting the variability in nephron numbers at birth and the complexities of interpreting creatinine levels in the first days of life. The guests discuss the long-term effects of neonatal AKI, the importance of follow-up care, and strategies for supporting kidney health in the NICU and beyond. They emphasize the need for a partnership between neonatology and nephrology to improve outcomes. Dr. Askenazi introduces the Neonatal Kidney Collaborative (NKC), explaining its mission to advance research, education, and advocacy in neonatal nephrology. Dr. Beck shares her experience as a trainee involved with the NKC, highlighting the mentorship opportunities available. The episode concludes with a look towards the future of neonatal nephrology research, including potential therapies and the evolving approach to renal replacement therapy in newborns. This informative discussion provides valuable insights for both neonatologists and nephrologists caring for vulnerable newborns. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

20.08.2024

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57 Min.
$#450 - [Journal Club] - 🫀 From The Heart - Does Early Hydrocortisone Actually Move the Needle in Fluid-Refractory Shock?$

vor 3 Tagen

#450 - [Journal Club] - 🫀 From The Heart - Does Early Hydrocortisone Actually Move the Needle in Fluid-Refractory Shock?

Send us Fan Mail In this double-blind randomized controlled trial from northern India, Nim and Adrianne review whether early hydrocortisone reduces 14-day all-cause mortality in preterm infants with fluid-refractory shock. The primary outcome showed no statistically significant difference between groups, though an 11 percent absolute reduction in mortality in the hydrocortisone group raised clinical interest. A major limitation was the high rate of open-label steroid crossover, with over 70 percent of both groups ultimately receiving hydrocortisone. The study highlights the difficulty of achieving equipoise when clinicians already believe strongly in a therapy, and raises important questions about study design in neonatal shock research. ---- Early hydrocortisone verses placebo in neonatal shock- a double blind Randomized controlled trial. Dudeja S, Saini SS, Sundaram V, Dutta S, Sachdeva N, Kumar P.J Perinatol. 2025 Mar;45(3):342-349. doi: 10.1038/s41372-025-02222-3. Epub 2025 Feb 13.PMID: 39948354 Clinical Trial. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

vor 3 Tagen

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17 Min.
04.01.2022 • Nur Abonnent:innen

#002 - Pulmonary - FLF clearance, diaphragmatic paralysis

In this episode we review questions 2 and 3 from the pulmonary section of the Neonatology Review Q&A book (3rd edition). Please subscribe to the podcast for access to daily episodes, and tips/strategies from Dr. Brodsky and Dr. Martin. If you have any questions feel free to email the show at nicupodcast@gmail.com You can also contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd. You can purchase copies of Neonatology books by following this link: https://www.lulu.com/spotlight/neonatologyreview

04.01.2022

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18 Min.
16. Juni

#448 - Are NICU Outcomes Actually Getting Better Over Time? (ft Dr. Joseph Kaempf)

Send us Fan Mail What does it mean to truly improve outcomes for very low birth weight infants, and are we actually doing it? In this episode, Daphna sits down with Dr. Joseph Kaempf, neonatologist and Medical Director of Value Research and Innovation at Providence Health System in Oregon, to examine some uncomfortable truths about neonatal quality improvement. Dr. Kaempf shares findings from a study spanning 16 NICUs over 14 years showing that composite morbidity outcomes have remained flat while length of stay has increased. He explores why traditional QI tools like driver diagrams and PDSA cycles may no longer be sufficient, and why augmented intelligence may be the next frontier. The conversation also touches on culture as a driver of NICU performance and the gap between institutional interests and true shared decision-making with families. A candid episode for anyone invested in the future of neonatology. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

16. Juni

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49 Min.
11. Apr. • Nur Abonnent:innen

#176 - 🍼 Fluid Electrolyte Nutrition & Renal - Questions: 64, 65, 66, 70

To learn more and have access to show notes and articles mentioned in this episode, go to www.the-incubator.org/review Please subscribe to the podcast for access to daily episodes. If you have any questions feel free to email the show at nicupodcast@gmail.com You can also contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd.

11. Apr.

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9 Min.
11. Apr. • Nur Abonnent:innen

#174 - 🍼 Fluid Electrolyte Nutrition & Renal - Questions: 40, 41, 45, 46

To learn more and have access to show notes and articles mentioned in this episode, go to www.the-incubator.org/review Please subscribe to the podcast for access to daily episodes. If you have any questions feel free to email the show at nicupodcast@gmail.com You can also contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd.

11. Apr.

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9 Min.
11. Apr. • Nur Abonnent:innen

#175 - 🍼 Fluid Electrolyte Nutrition & Renal - Questions: 53, 57, 63

To learn more and have access to show notes and articles mentioned in this episode, go to www.the-incubator.org/review Please subscribe to the podcast for access to daily episodes. If you have any questions feel free to email the show at nicupodcast@gmail.com You can also contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd.

11. Apr.

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13 Min.
vor 4 Tagen

#450 - [Journal Club] - 🫀From The Heart - When Nitric Oxide Fails: Is the Left Ventricle the Culprit in Septic Preterm Infants?

Send us Fan Mail In this retrospective single-center study from Toronto, Adrianne and Nim explore the echo findings of preterm infants with septic shock and hypoxemic respiratory failure. Contrary to the common assumption that elevated pulmonary vascular resistance drives hypoxemia in sepsis, the data points to left ventricular dysfunction as a key contributor. Babies with hypoxemic respiratory failure showed lower LV systolic and diastolic performance, while pulmonary pressures were similar between groups. Mortality was significantly higher in the hypoxemic group. This challenges the reflex to reach for nitric oxide first and asks clinicians to look at the whole heart. ---- Cardiopulmonary Physiology of Hypoxemic Respiratory Failure Among Preterm Infants with Septic Shock. Kharrat A, Nissimov S, Zhu F, Deshpande P, Jain A.J Pediatr. 2025 Mar;278:114384. doi: 10.1016/j.jpeds.2024.114384. Epub 2024 Nov 6.PMID: 39510164 Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

vor 4 Tagen

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23 Min.
vor 4 Tagen

#450 - [Journal Club] - 🫀From The Heart - When Nitric Oxide Fails: Is the Left Ventricle the Culprit in Septic Preterm Infants?

In this retrospective single-center study from Toronto, Adrianne and Nim explore the echo findings of preterm infants with septic shock and hypoxemic respiratory failure. Contrary to the common assumption that elevated pulmonary vascular resistance drives hypoxemia in sepsis, the data points to left ventricular dysfunction as a key contributor. Babies with hypoxemic respiratory failure showed lower LV systolic and diastolic performance, while pulmonary pressures were similar between groups. Mortality was significantly higher in the hypoxemic group. This challenges the reflex to reach for nitric oxide first and asks clinicians to look at the whole heart. ---- Cardiopulmonary Physiology of Hypoxemic Respiratory Failure Among Preterm Infants with Septic Shock. Kharrat A, Nissimov S, Zhu F, Deshpande P, Jain A.J Pediatr. 2025 Mar;278:114384. doi: 10.1016/j.jpeds.2024.114384. Epub 2024 Nov 6.PMID: 39510164 Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

vor 4 Tagen

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22 Min.
11.07.2021

#011 - Journal Club - BPD prevention, Cortisol levels, Home NG feeds, MRI and outcomes, Renal insufficiency and more

Send us Fan Mail As always, feel free to send us questions, comments or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd. Papers discussed in today's episode are listed and timestamped below. enjoy! 03:35 - https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2781459 14:35 - https://jpeds.com/retrieve/pii/S0022347620315675 23:35 - https://jpeds.com/retrieve/pii/S0022347621002298 28:40 - https://dx.doi.org/10.1016/j.jpeds.2021.03.046 40:08 - https://www.jpeds.com/article/S0022-3476(21)00219-5/fulltext 47:45 - https://www.jpeds.com/article/S0022-3476(21)00114-1/fulltext 51:48 - https://www.nature.com/articles/s41372-021-01097-4 57:08 - https://www.nature.com/articles/s41372-020-00808-7 63:20 - https://www.nature.com/articles/s41372-021-01082-x 68:04 - https://www.nature.com/articles/s41372-021-00988-w 70:35 - https://www.nature.com/articles/s41372-020-00911-9 74:40 - https://www.nature.com/articles/s41372-020-0746-6 77:14 - https://www.nature.com/articles/s41372-021-01021-w 78:30 - https://www.nature.com/articles/s41372-020-00850-5 81:02 - https://www.nature.com/articles/s41372-021-01081-y 82:38 - https://www.nature.com/articles/s41372-021-01035-4 83:50 - https://www.nature.com/articles/s41372-021-00963-5 Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

11.07.2021

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1 Std. 31 Min.

Ben and Daphna go through daily neonatal board questions. If you are studying for the upcoming neonatal boards exam or just want to keep your neonatal knowledge sharp, this is the podcast for you. This show is done in collaboration with Neonatology Review (Dr. Dara Brodsky and Dr. Camilia Martin).

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The neonatology focused podcast hosted by Dr. Ben Courchia MD & Dr. Daphna Yasova Barbeau.

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