Deep Breaths: Updates from CHEST

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Welcome to the  Deep Breaths: Updates from CHEST series, dedicated to championing the prevention, diagnosis, and treatment of lung and chest diseases. Check out CHEST leaders and advocates sharing the latest in chest medicine education, clinical research, and team-based care in the areas of pulmonary diseases, critical care, and sleep medicine. Learn more about the latest diagnostic and treatment advances in pulmonology and critical care below.

  1. 6. MÄRZ

    What Type 2 Inflammation in COPD Means for Treatment Decision Making

    Host: Stephanie Christenson, MD Guest: Diego Maselli, MD, FCCP COPD is increasingly recognized as a heterogeneous disease, and for a subset of patients, type 2 inflammation plays a meaningful role in exacerbation risk and treatment response. Given that, Drs. Stephanie Christenson and Diego Maselli come together to examine how insights into the pathobiology of type 2 inflammation can directly inform clinical decision making in COPD. Specifically, they discuss the practical use of blood eosinophil counts to phenotype patients, assess risk, and guide therapy selection within the context of GOLD 2025 and 2026 guidance. Dr. Christenson is an Associate Professor at the University of California San Francisco in the Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, and Dr. Maselli is a Professor of Medicine at the Long School of Medicine at UT Health in San Antonio. This episode of Deep Breaths: Updates from CHEST was supported by a non-promotional, non-CME educational program brought to you by CHEST in collaboration with and sponsored by GSK.

    15 Min.

  2. 10. FEB.

    Escalating COPD Care: From Flares to Long-Term Control

    Guest: Ravi Kalhan, MD Guest: MeiLan K. Han, MD, MS For patients with chronic obstructive pulmonary disease (COPD), exacerbations are early indicators of disease progression—not just isolated events. In this expert-led discussion, Drs. Ravi Kalhan and Meilan Han break down the latest GOLD updates, explain how to use eosinophil counts to guide treatment, and discuss when to consider adding biologic therapy. Dr. Kalhan is the Louis A. Simpson Professor of Pulmonary Medicine and Director of the Asthma and COPD Program at Northwestern Medicine in Chicago. Dr. Han is a Professor of Medicine and Chief of the Division of Pulmonary and Critical Care at the University of Michigan Health in Ann Arbor. This episode of Deep Breaths: Updates from CHEST was supported by a non-promotional, non-CME educational program brought to you by CHEST in collaboration with and sponsored by GSK.

    17 Min.

  3. 2. JAN.

    Recognizing Methamphetamine-Associated PAH: Strategies for Complex Care

    Faculty: Rodolfo A. Estrada MD, FCCP Faculty: Steven M. Hollenberg, MD Faculty: Dana Kay, DO Subtle symptoms and overlooked risk factors can delay diagnosis of methamphetamine-associated pulmonary arterial hypertension (PAH), especially given regional differences in clinical practice and access to care. Dr. Rodolfo Estrada speaks with Drs. Steven Hollenberg and Dana Kay about improving clinical awareness, navigating treatment challenges, and understanding the value of collaborative, patient-centered care. Dr. Estrada is an Associate Professor of Internal Medicine in the Division of Pulmonary and Critical Care and the Director of the Pulmonary Hypertension Program at the University of Texas in San Antonio. Dr. Hollenberg is a Professor of Medicine at the Emory University School of Medicine and the Director of Cardiac Intensive Care at the Emory Heart and Vascular Institute in Atlanta. Dr. Kay is an Assistant Professor of Clinical Medicine in the Division of Pulmonary and Critical Care at the University of Cincinnati. This program is produced in partnership with the American College of Chest Physicians and is sponsored by Actelion Pharmaceuticals US, Inc. For further expert insight, view the on demand CHEST webinar on Methamphetamine-Associated Pulmonary Arterial Hypertension: VIEW NOW »

    17 Min.

  4. 22.12.2025

    Clinical Updates in Non-Small Cell Lung Cancer: From Surveillance to Treatment

    Guest: Gerard A. Silvestri MD, MS, Master FCCP Guest: Adam H. Fox, MD, MSc Guest: Anurag Singh, MD, PhD From updated surveillance strategies to evolving biopsy techniques and treatment advances, recent findings presented at 2025 conferences are reshaping non-small cell lung cancer management. Dr. Gerard Silvestri speaks with Drs. Adam Fox and Anurag Singh to explore key data influencing diagnostic decisions, patient-centered care, and multidisciplinary treatment planning across stages. Dr. Silvestri is a pulmonologist and the Hillenbrand Professor of Thoracic Oncology at the Medical University of South Carolina. Dr. Fox is a pulmonologist and Assistant Professor of Medicine at the Medical University of South Carolina. Dr. Singh is a Professor of Radiation Oncology and the Director of Radiation Research at the Roswell Park Cancer Center in New York. This program is produced in partnership with the American College of Chest Physicians and is sponsored by AstraZeneca.

    18 Min.

  5. 22.12.2025

    Redefining Non-Small Cell Lung Cancer Care: Updates in Targeted and Perioperative Therapy

    Guest: Gerard A. Silvestri MD, MS, Master FCCP Guest: Mariam Alexander, MD, PhD Guest: Jessica S. Donington, MD, MSCR The 2025 European Society for Medical Oncology Congress and World Conference on Lung Cancer revealed significant updates in non-small cell lung cancer care. Learn more as Drs. Gerard Silvestri, Mariam Alexander, and Jessica Donington review new data on EGFR- and ROS1-targeted therapies, perioperative immunotherapy, and multidisciplinary strategies to expand resectability in stage III non-small cell lung cancer. Dr. Silvestri is a pulmonologist and the Hillenbrand Professor of Thoracic Oncology at the Medical University of South Carolina. Dr. Alexander is an Assistant Professor of Medical Oncology at the Medical University of South Carolina. Dr. Donington is a Professor in Surgery and Chief of the Section of Thoracic Surgery at the University of Chicago. This program is produced in partnership with the American College of Chest Physicians and is sponsored by AstraZeneca.

    17 Min.

  6. 07.10.2025

    Next Steps in COPD Care: Exploring Biologics for Frequent Exacerbators

    Host: Diego Maselli, MD, FCCP Guest: Stephanie Christenson, MD Despite triple inhaled therapy, many patients with chronic obstructive pulmonary disease (COPD) continue to experience frequent and severe exacerbations, leading to hospitalizations, symptom burden, and higher mortality risk. In this expert-led discussion, Drs. Diego Maselli and Stephanie Christenson personalized treatment approaches and the role of biologics in advanced COPD care. Dr. Maselli is a Professor of Medicine at the Long School of Medicine at UT Health San Antonio, and Dr. Christenson is an Associate Professor in the Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine and an attending physician on the Pulmonary Consult Service and in the Pulmonary Clinic at the University of California in San Francisco. This program is produced in partnership with the American College of Chest Physicians and is sponsored by Sanofi and Regeneron Pharmaceuticals, Inc.

    20 Min.

  7. 30.09.2025

    New Frontiers in COPD and Emphysema: Personalized Therapies and Minimally Invasive Options

    Moderator: Amit Bobby Mahajan, MD, FCCP, DAABIP Guest: Jonathan Kurman, MD Guest: Surya Bhatt, MD New strategies like advanced pharmacologic agents and bronchoscopic lung volume reduction are redefining COPD and emphysema management. Dr. Bobby Mahajan sits down with Drs. Surya Bhatt and Jonathan Kurman to highlight emerging strategies for identifying ideal candidates, optimizing patient selection, and combining therapies to reduce dyspnea and improve outcomes. Dr. Mahajan is the Medical Director of Interventional Pulmonology and Complex Airway Disease Programs at the Inova Health System in Virginia, Dr. Bhatt is the Director of the Center for Lung Analytics and Imaging Research as well as the Medical Director of the Pulmonary Function and Exercise Physiology Lab and the Pulmonary Rehabilitation Program at the University of Alabama at Birmingham, and Dr. Kurman is an Associate Professor of Medicine at the Medical College of Wisconsin and the Director of Interventional Pulmonology at Froedtert and Medical College of Wisconsin Health Network. This program is produced in partnership with the American College of Chest Physicians and is sponsored by Pulmonx, the maker of the Zephyr Valve.

    17 Min.

  8. 16.09.2025

    Evolving Strategies in Resectable NSCLC: Insights from ASCO and ASTRO 2025

    Moderator: Gerard A. Silvestri MD, MS, Master FCCP Guest: Jessica S. Donington, MD, MSCR Guest: Mariam Alexander, MD, PhD Guest: Anurag Singh, MD Recent data from ASCO and ASTRO 2025 are redefining standards of care for resectable non-small cell lung cancer (NSCLC). Drs. Gerard Silvestri, Mariam Alexander, Anurag Singh, and Jessica Donington review these updates on the importance of molecular testing, careful surgical selection, and multidisciplinary planning to optimize personalized treatment pathways. Dr. Silvestri is a pulmonologist and the Hillenbrand Professor of Thoracic Oncology at the Medical University of South Carolina; Dr. Alexander is an Assistant Professor of Medical Oncology at the Medical University of South Carolina; Dr. Singh is the Director of Radiation Research, Director of Head and Neck and Lymphoma Radiation Services, and the Associate Dean of Graduate Medical Education in Radiation Medicine at Roswell Park Comprehensive Cancer Center in Buffalo, New York; and Dr. Donington is a Professor of Surgery and Chief of the Section of Thoracic Surgery at the University of Chicago. This program is produced in partnership with the American College of Chest Physicians and is sponsored by AstraZeneca.

    16 Min.
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Welcome to the  Deep Breaths: Updates from CHEST series, dedicated to championing the prevention, diagnosis, and treatment of lung and chest diseases. Check out CHEST leaders and advocates sharing the latest in chest medicine education, clinical research, and team-based care in the areas of pulmonary diseases, critical care, and sleep medicine. Learn more about the latest diagnostic and treatment advances in pulmonology and critical care below.

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    Deep Breaths: Updates from CHEST

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