This Week in Startups

Jason Calacanis

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

  1. From hypercars to cruise missiles: Lukas Czinger on the future of US defense | E2292

    8 TIMER SIDEN

    From hypercars to cruise missiles: Lukas Czinger on the future of US defense | E2292

    This Week In Startups is made possible by: Every.io https://every.io Shopify https://shopify.com/twist Render https://render.com/twist Plaud https://Plaud.ai/twist Today’s show: Startups like Divergent Technologies are producing components and aircraft for the military through new systems that are better, faster, and cheaper than conventional methods. CEO and co-founder Lukas Czinger stops by TWiST to share the company’s vertically integrated, AI-driven manufacturing platform and how he transitioned from hypercar parts to working directly with the Pentagon on autonomous aircraft. Plus, 50 million Americans are on antidepressants, and it’s not necessarily the right treatment for all of them. Outro Health co-founders Brandon Goode and Dr. Mark Horowitz share their hyperbolic tapering method, which helps patients get off drugs like Zoloft and Prozac without suffering through traumatic and potentially dangerous side effects. Guests Lukas Czinger: https://x.com/lukasczinger Divergent Technologies: https://www.divergent3d.com Czinger Vehicles: https://www.czinger.com/ Brandon Goode: https://www.linkedin.com/in/goodebrandon/ Dr. Mark Horowitz: https://x.com/markhoro Outro Health: https://outro.com Timestamps: 0:00 Divergent shifted from hypercar development to 3D printing all kinds of components 1:33 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off! 4:10 How 3D printing has exponentially improved 8:18 Making military components faster, better, and cheaper 9:58 Every.io - For all of your incorporation, banking, payroll, benefits, accounting, taxes or other back-office administration needs, visit https://every.io 11:00 How Divergent caught the Pentagon's attention 19:51 Shopify - Turn those What Ifs into sales with the ecommerce platform powering millions of businesses. Sign up for your $1-per-month trial today at https://shopify.com/twist 25:29 Why Outro Health helps patients taper off SSRIs 30:06 Render - Find out why 5 million developers are already using the all-in-one cloud platform, Render. Go to https://render.com/twist and apply for the Render Startup Program to get $500-$100,000 in free credits, depending on your stage and backers. 36:37 Is depression caused by a "chemical imbalance"? 46:37 Understanding the hyperbolic tapering method 58:32 How Outro makes money 1:10:01 Leaked Meta layoff audio 1:13:41 Cloudflare CEO drops "measurer" roles 1:18:16 CrowdHealth - CrowdHealth lets you ditch the bureaucracy with a peer-to-peer funding platform for your healthcare. Get started for $99 per month for your first three months by using the code TWIST at https://JoinCrowdHealth.com/twist. 1:19:17 Why Trump canceled his AI executive order 1:28:08 Polymarket sharps on Russia vs. Ukraine, SpaceX ticker symbol 1:33:34 Luel vs. Kled update: Is this nepotism at work? 1:37:02 Chris Nolan doesn't have a smartphone 1:43:04 Jason's favorite new espresso machine Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Lon: X: https://x.com/lons Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Check out all our partner offers: https://partners.launch.co/ Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com

    1 t. 47 min.
  2. Avi Patel on the startup that copied Kled and why he called out General Catalyst by name | E2291

    2 DAGE SIDEN

    Avi Patel on the startup that copied Kled and why he called out General Catalyst by name | E2291

    This Week In Startups is made possible by: Grasshopper Bank - https://grasshopper.bank/twist LinkedIn - https://linkedIn.com/twist Northwest Registered Agent - https://northwestregisteredagent.com/twistPlaud - https://Plaud.ai/twist  Why raise $200 million if you are already profitable? That’s the question Jason and Alex put to Mercury’s founder and CEO, Immad Akhund, after the entrepreneur raised another massive round for his upstart, technology-friendly bank. TWiST then welcomed Kled founder Avi Patel to discuss the startup he considers a clear ripoff of his own company. Jason gavels in verdicts on all parties involved, including Y Combinator and venture capital firm General Catalyst. The show closes with a news lightning round, including OpenAI’s decision to offer $2 million in token credits to hundreds of startups. Guest Links: Mercury https://mercury.com Mercury funding announcement https://www.businesswire.com/news/home/20260520511817/en/Mercury-Raises-$200-Million-Series-D-at-$5.2B-Valuation Immad Akhund on X https://x.com/immad Kled https://www.kled.ai/ Avi Patel on X https://x.com/avipat_/ Avi’s complaint https://x.com/avipat_/status/2055384102409253056 General Catalyst https://www.generalcatalyst.com/ Y Combinator https://www.ycombinator.com/ Delve https://techcrunch.com/2026/04/23/another-customer-of-troubled-startup-delve-suffered-a-big-security-incident/ Discussion links: Anthropic’s attack on secondary trading https://techcrunch.com/2026/05/12/anthropic-warns-investors-against-secondary-platforms-offering-access-to-its-shares/ Vanta https://www.vanta.com/twist Timestamps: 0:00 Welcome to This Week in Startups! 2:14 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off! 3:27 Immad Akhund (Mercury) joins to discuss $200M raise 6:33 Mercury's origin story and path to $650M run rate 9:53 Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at https://northwestregisteredagent.com/twist 14:23 Stablecoins: where they work, why Mercury won't launch its own 20:13 LinkedIn - Thanks to our partners at LinkedIn! Post your job for free at https://linkedIn.com/twist then promote it to get access to LinkedIn Jobs' new AI assistant. 22:38 AI agents, and the future of money movement 27:30 Why Mercury raised less this round 30:11 Grasshopper Bank - Time is money. Don't waste either. Go to https://grasshopper.bank/twist and get an exclusive $500 cash bonus just for opening an account. 42:48 Avi Patel (Kled) joins to discuss copycat startups 57:06 Jason's verdict on YC's hacker culture & "appearance of impropriety" 1:17:39 Sam Altman's $2M-in-tokens-for-equity offer to YC founders 1:24:32 NYC hotel housekeepers cross $100K in time under new union contract 1:30:14 Minimum wage, immigration & the case for raising it slowly Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Lon: X: https://x.com/lons Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Check out all our partner offers: https://partners.launch.co/ Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com

    1 t. 34 min.
  3. Why does Gen Z hate AI?

    4 DAGE SIDEN

    Why does Gen Z hate AI?

    This Week In Startups is made possible by: Vanta - Vanta.com/TWIST Sentry - Sentry.io/TWIST Deel - Deel.com/TWIST Today’s show: AI is the villain of the 2026 commencement cycle, with business luminaries — including Eric Schmidt — booed for discussing or praising the technology. As students graduate into a job market forcibly reshaped by AI, increasingly negative public polling on the potential impacts of artificial intelligence on society is clearly not missing the mark. Jason and Alex then discussed The Information’s reporting that Anthropic and OpenAI earn nearly 90% of all startup AI revenue, a Stanford student’s viral essay regarding their time at the university in a post-ChatGPT world, Flock Safety’s impressive (and worrying) web of cameras, and the upcoming Mark II AI bookmark. The episode closes with questions from our live audience! TWIST Links: Bounty website https://www.thisweekinstartups.com/bounty Sidebar bounty challenge https://www.notion.so/launch1/5K-Bounty-Create-Sidebar-App-for-Podcasts-34150ff313d280adbd8ed6204676513c Annotated.com bounty challenge https://annotated.lovable.app/ Timestamps: 0:00 TWiST All-Stars summer lineup announcement 2:43 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off! 5:08 Eric Schmidt booed at University of Arizona commencement 8:57 Why Gen Z feels "double-crossed" by AI leaders 10:10 Deel - Founders scale faster on Deel. Set up payroll for any country in minutes, hire anyone anywhere, get visas handled fast, and get back to building. Visit https://deel.com/twist to learn more. 15:22 Is this AI's Vietnam moment? The anti-war parallel 18:04 Theo Baker's NYT essay on Stanford's AI cheating culture 19:24 Sentry - New users can get $240 in free credits when they go to https://sentry.io/twist and use the code TWIST 22:30 Why Jason says everyone should start a company 28:59 Anthropic + OpenAI capture 89% of AI startup revenue 30:17 Vanta: Get $1000 off your SOC 2 at https://www.vanta.com/twist 31:57 Are token sales a duopoly? Negative gross margins debate 35:17 Risk of building app-layer startups on top of foundation models 38:22 Inside Tracker bounty update: AI sidebar + Annotated.com 41:18 Mark II: the $159 AI bookmark Alex wants 49:31 Flock Safety solves Austin shooting via Manor PD 53:39 DeFlock map and the geography of surveillance in Texas 1:03:42 Noti Gang: AI for filing patents 1:05:45 Noti Gang: Running AI models locally on Mac Studios Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Check out all our partner offers: https://partners.launch.co/ Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com

    1 t. 9 min.
  4. The Self-Driving Startup Nobody Saw Coming | E2289

    15. MAJ

    The Self-Driving Startup Nobody Saw Coming | E2289

    This Week In Startups is made possible by: IM8 Health: IM8health.com/TWIST Squarespace: Squarespace.com/TWIST Render - Render.com/TWIST Self-driving just stopped being a science problem and became an engineering challenge instead. That's the through-line of today’s double-header with the CEOs of two of the most important AV companies in the world — Wayve's Alex Kendall and Waabi's Raquel Urtasun. Between them: ~$2B raised in the last six months, Uber as a partner, Nissan and Volvo as OEMs, and a shared bet that end-to-end AI plus world models beats Waymo's city-by-city map-and-pray approach. If you want to understand the state of the self-driving industry beyond recent Waymo announcements, this is the episode for you. Guest Links: Wayve: wayve.ai/ Waabi: http://waabi.ai/ Alex Kendall https://www.linkedin.com/in/alexgkendall/ Raquel Uratsun: https://www.linkedin.com/in/raquel-urtasun-298400139/ Company Links: Wayve’s GAIA-2 world model: https://wayve.ai/thinking/gaia-2/ Wayve’s 500 city roadshow: https://wayve.ai/thinking/ai-500-roadshow-500-cities/ Wavye’s most recent funding round: https://wayve.ai/press/series-d/ Waybe + Uber: https://wayve.ai/press/wayve-nissan-uber-robotaxi-collaboration/ Waabi closed-loop simulator: https://waabi.ai/insights/waabi-world Waabi + Volvo: https://waabi.ai/insights/waabi-and-volvo-autonomous-solutions-partner-to-jointly-develop-and-deploy-autonomous-transportation-solutions Waabi + Uber: https://www.uberfreight.com/en-US/blog/uber-freight-and-waabi-introduce-industry-first-autonomous-truck-deployment-solution Timestamps: 0:00 Alex Kendall (Wayve) joins the show 1:19 The contrarian bet on end-to-end AI and world models in 2017 3:05 What is a world model? GAIA-2 and GAIA-3 explained 7:34 Sensor agnosticism: camera, radar, LiDAR and minimum bar for safety 9:56 $1.5B raised — have we cracked self-driving? 10:09 Render: Find out why 5 million developers are already using the all-in-one cloud platform, Render. Go to https://render.com/twist and apply for the Render Startup Program to get $500-$100,000 in free credits, depending on your stage and backers. 20:38 Squarespace: Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST 25:03 How consumers will actually pay: bundle, subscription, or free trial 30:15 IM8 Health: Start feeling like your best self every day. Go to https://IM8health.com/twist and use the code TWiST to get a free welcome kit, five free travel sachets, and 10% off your order. 35:59 Raquel Urtasun (Waabi) joins the show 36:25 World models as controllable simulators for physical AI 43:34 One AI brain across trucks, robotaxis, and beyond 47:35 What changed in AI to make 2026 the deployment year 52:28 Why Waabi raised $1B when they're capital-efficient 58:52 Where Waabi is today: Volvo VNL Autonomous, Dallas-Houston, Uber Freight 1:00:50 Per-mile pricing and the Driver-as-a-Service model 1:07:20 Has Uber tried to buy Waabi? "Not for sale" Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Lon: X: https://x.com/lons Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Check out all our partner offers: https://partners.launch.co/ Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com

    1 t. 13 min.
  5. How Many Startups Will Survive OpenAI? | E2288

    13. MAJ

    How Many Startups Will Survive OpenAI? | E2288

    This Week In Startups is made possible by:Pilot -⁠ https://Pilot.com/TWIST⁠Grasshopper Bank -⁠ https://Grasshopper.bank/TWIST⁠Quo -⁠ https://Quo.com/TWiST⁠Plaud - ⁠https://Plaud.ai/twist⁠Anthropic just declared every unauthorized secondary sale of its stock "void" — naming Hiive, Forge, Sydecar, Upmarket, and others in a public hit list. Jason and Alex sit down with Jenny Fielding (Everywhere Ventures), Dave McClure (Practical VC), and Sam Lessin (Slow Ventures) to unpack what the AI lab’s move to limit secondary trades means for SPV operators, brokers, and the founders trying to keep control of their cap tables. Plus: a real story of a founder who returned a $15M Series A six months after closing because Claude was going to eat his startup, SaaS moats, and just what does it mean to be rich?Timestamps:0:00 Guest introductions0:48 Anthropic voids unauthorized SPV trades8:41 Accredited investor reform & the SEC sophisticated investor test8:58 Quo (formerly OpenPhone) - Quo gives you a clean, modern way to handle every customer call, text, and thread all in one place. Try it free at https://quo.com/TWiST11:43 Naval's USVC closed-end fund as a workaround16:41 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!17:48 Pro-rata rights battles: when Series A investors push seed investors out19:36 Grasshopper Bank: Time is money. Don't waste either. Go to https://grasshopper.bank/twist and get an exclusive $500 cash bonus just for opening an account.29:13 Pilot: Focus on your product, let Pilot handle your bookkeeping. Pilot provides the most reliable accounting, CFO, and tax services for startups and small businesses. Head to https://pilot.com/twist and get $1,200 off your first year.30:23 Storing wealth in stories vs. cash flows34:19 Cerebras and Fervo Energy IPOs — meaningful liquidity?37:54 Will SpaceX, Anthropic, OpenAI IPOs redistribute capital or compound it?45:58 The $15M Series A founder who returned the money because of Claude50:01 Should founders pivot or return capital when the world changes?56:43 OpenAI's $6.6B tender and Shruti Gandhi's viral SF cost-of-living tweet1:00:25 Intercom rebrands to Fin: the AI-first late-stage pivotSubscribe to the TWiST500 newsletter:⁠ https://ticker.thisweekinstartups.com⁠Check out the TWIST500:⁠ https://www.twist500.com⁠Subscribe to This Week in Startups on Apple:⁠ https://rb.gy/v19fcp⁠Follow Lon:X:⁠ https://x.com/lons⁠Follow Alex:X:⁠ https://x.com/alex⁠LinkedIn:⁠ ⁠https://www.linkedin.com/in/alexwilhelm⁠Follow Jason:X:⁠ https://twitter.com/Jason⁠LinkedIn:⁠ https://www.linkedin.com/in/jasoncalacanis⁠Check out all our partner offers:⁠ https://partners.launch.co/⁠Great TWIST interviews:⁠ Will Guidara,⁠⁠ Eoghan McCabe⁠,⁠ Steve Huffman⁠,⁠ Brian Chesky⁠,⁠ Bob Moesta,⁠⁠ Aaron Levie⁠,⁠ Sophia Amoruso⁠,⁠ Reid Hoffman⁠,⁠ Frank Slootman⁠,⁠ Billy McFarland⁠Check out Jason’s suite of newsletters:⁠ https://substack.com/@calacanis⁠Follow TWiST:Twitter:⁠ https://twitter.com/TWiStartups⁠YouTube:⁠ https://www.youtube.com/thisweekin⁠Instagram:⁠ https://www.instagram.com/thisweekinstartups⁠TikTok:⁠ https://www.tiktok.com/@thisweekinstartups⁠Substack:⁠ https://twistartups.substack.com⁠

    1 t. 25 min.
  6. How the 1% Will Own Compute (and What It Means for You)

    13. MAJ ·  BONUSINDHOLD

    How the 1% Will Own Compute (and What It Means for You)

    The future of AI isn't a smarter chatbot. It's a model that watches your screen, listens to the room, and acts on what it sees. We dug into Thinking Machines' new interaction model, what it means for compute, and the layoff wave that's already here.This week's roundtable: Anastasios Angelopoulos (CEO of Arena, formerly LMArena), Nick Harris (CEO of Lightmatter, photonic computing chips), and Philip Johnston (CEO of StarCloud, building megawatt data centers in space). Thank you to our exclusive sponsor: PayPal Open, One Platform for All Business: http://paypalopen.com/ Timestamps: 0:00 Cold open 1:21 Welcome to Episode 13 2:51 Is China closing the AI gap? Arena's data 5:16 Lightmatter and the photonic interconnect bottleneck 9:42 StarCloud 2, Nvidia Space Ruben 1, and orbital data centers 17:24 Thinking Machines' interaction model: what's actually new 28:22 Whisper Flow and the 3-pedal desk setup 33:48 Real-time desktop and camera awareness as the real unlock 40:25 Why this 100x's compute demand 42:43 The polarization of compute and $10M personal data centers 49:25 The layoff wave: Cloudflare, PayPal, Coinbase, Upwork 54:48 The 10x gap between AI-first and non-AI-first employees 59:52 Unlimited agency and the abundance future 1:00:46 Anthropic's Project Luna runs a retail store 1:03:45 Decoupling labor from value creation 1:05:03 P(doom) round 🔗 Guests: Anastasios Angelopoulos, Arena: https://arena.ai | @ML_Angelopolous Nick Harris, Lightmatter: https://lightmatter.co Philip Johnston, StarCloud: https://starcloud.com | @philipjohnston 🔗 Referenced in this episode: Thinking Machines, Introducing Interaction Models: https://thinkingmachines.ai/blog/interaction-models/ LMArena leaderboard: https://lmarena.ai Lightmatter: https://lightmatter.co Starcloud: https://www.starcloud.com TechCrunch, Cloudflare says AI made 1,100 jobs obsolete: https://techcrunch.com/2026/05/08/cloudflare-says-ai-made-1100-jobs-obsolete-even-as-revenue-hit-a-record-high/ Fast Company, Tech layoffs this week due to AI (Cloudflare, PayPal, Coinbase, Upwork): https://www.fastcompany.com/91538995/tech-layoffs-due-to-ai-this-week-cloudflare-paypal-coinbase-upwork Bloomberg, South Korea floats citizen dividend from AI profits: https://www.bloomberg.com/news/newsletters/2026-05-12/korea-s-massive-ai-boom-triggers-call-for-tech-tax-roiling-market PYMNTS, Inside a retail store run entirely by AI (Andon Labs / Luna): https://www.pymnts.com/artificial-intelligence-2/2026/inside-a-retail-store-run-entirely-by-ai/ Wispr Flow (voice-to-text tool Jason uses): https://wisprflow.ai Fermi Paradox: https://en.wikipedia.org/wiki/Fermi_paradox 🔗 Subscribe and follow: Newsletter and all platforms: https://thisweekinai.ai #ThisWeekInAI #AI #ThinkingMachines #Lightmatter #StarCloud #Arena #Anthropic #ProjectLuna #AIcompute #AIlayoffs #Superintelligence

    1 t. 8 min.
  7. Cerebras's IPO goes vertical, and the death of OpenClaw? | E2287

    11. MAJ

    Cerebras's IPO goes vertical, and the death of OpenClaw? | E2287

    Today’s show: Cerebras just jacked its IPO range to $150–$160 a share, OpenAI bought a consulting firm to seed its $4 billion private-equity joint venture, and a startup in Oakland is electrolyzing magnesium out of seawater for one-third the going price. Alex Wilhelm and Jason Calacanis go deep with AI21 co-CEO Ori Goshen on why model orchestration, not bigger LLMs, will decide who wins enterprise AI. The crew also covered the decline of OpenClaw, TikTok's new £3.99 ad-free tier, more entries in the live-show sidebar bounty, and had time for a little Off Duty before signing off. Guest Links: Ori Goshen on LinkedIn AI21 Alex Grant on LinkedIn Magrathea Metals Timestamps: 0:00 Ori Goshen, CEO of AI21 joins the show 1:20 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off! 5:14 Why enterprises care about token cost optimization 6:01 Jamba as open-weight; Maestro as proprietary orchestration 10:08 LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at https://LinkedIn.com/twist 12:56 AI21 customer roster: FNAC, US tech giants, Israeli companies 19:01 Alex Grant, CEO of Magrathea Metals joins to discuss pulling magnesium from seawater 20:03 Live video of the Oakland pilot electrolyzer 20:10 Deel - Founders scale faster on Deel. Set up payroll for any country in minutes, hire anyone anywhere, get visas handled fast, and get back to building. Visit https://deel.com/twist to learn more. 22:01 Magnesium as a "gateway metal" for aluminum, defense, aerospace 23:20 TETRA joint venture & the Evergreen Project in Arkansas 23:38 Series A close, JV economics: $3,000/ton vs. $7,000/ton market 29:10 Sidebar bounty update: Glass Sidebar (Oliver Choy) demo 30:47 Netsuite - Get the free business guide Demystifying AI at https://netsuite.com/twist 31:47 Sidebar bounty update: Sidecast (Patrick Hughes) demo 36:09 Reducing scope to "real-time fact checker only" for final round 37:24 Ro.co: Ro's insurance checker will let you know if your coverage includes GLP-1s for FREE. Go to https://Ro.co/Twist for your free insurance check. 39:07 Cerebras IPO: $115–$125 → $150–$160 per share 44:19 Will OpenAI's compute commitments to Cerebras actually get funded? 49:19 Fervo Energy IPO — venture-backed geothermal company going public 49:40 OpenAI Deployment Company + Tomoro acquisition explained 53:51 Anthropic's parallel $1.5B PE joint venture with Blackstone & Goldman 56:05 Why Jason thinks these PE spinouts are convoluted financial engineering 56:40 OpenClaw's decline + competition from Cowork, Perplexity, Grok 1:04:22 TikTok's £3.99 ad-free subscription launches in the UK 1:09:09 Knicks sweep 76ers — Jason's playoff predictions 1:11:24 Off-duty: "There Is No Antimemetics Division" by qntm 1:13:25 Off-duty: Fall of Civilizations podcast by Paul Cooper 1:16:37 States' rights, federalism, housing supply & closing thoughts Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Lon: X: https://x.com/lons Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Check out all our partner offers: https://partners.launch.co/ Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com

    1 t. 23 min.
  8. 5,000+ Tech Workers Laid Off This Week. It's Just The Beginning. | E2286

    9. MAJ

    5,000+ Tech Workers Laid Off This Week. It's Just The Beginning. | E2286

    This Week In Startups is made possible by: IM8 Health - https://IM8health.com/TWIST Every - Every.io Sentry - https://Sentry.io/TWIST Banks don’t want to hand over their data to AI labs. So David Moscatelli built a $250,000 box that runs AI on-prem. He already has 1,600 pre-orders. On today’s episode of TWiST, Jason and Alex sit down with the Go Abacus founder and Yanez's Jose Caldera to unpack how regulated industries are getting AI without the cloud, why Bittensor subnet 54 is incentivizing miners to attack identity systems, and why Cloudflare just laid off 20% of its workforce in the same week it raised guidance. The show closes with Jason explaining what it means to build an AI-first startup, and how workers can derisk their future employment! Guest Links: Go Abacus Go1 direct link David Moscatelli on LinkedIn Yanez Bittensor Subnet 54 on TAOstats Jose Caldera on LinkedIn LAUNCH Links: Founder University Founder University Japan application portal News Links: Cloudflare lays off 20% of its staff Coinbase cuts 14% of its staff Block post on how it is rebuilding its company Block’s earnings, including its raised guidance Anthropic’s massive upcoming funding round WHOOP’s new on-demand clinicians Stripe Atlas’s growth Timestamps: 0:00 Introduction: Jason in Brooklyn, Knicks playoffs 2:30 Go Abacus joins: AI infrastructure for regulated industries 3:25 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off! 4:00 The Go1: 2,000-user on-prem AI appliance 7:04 Pricing the Go1: How far does $250,000 go? 7:24 1,600 orders and the hardware delivery challenge 10:14 Sentry - New users can get $240 in free credits when they go to https://sentry.io/twist and use the code TWIST 20:23 Every.io - For all of your incorporation, banking, payroll, benefits, accounting, taxes or other back-office administration needs, visit https://every.io 27:22 Chicago tech scene and in-office culture 30:09 IM8 Health: Start feeling like your best self every day. Go to https://IM8health.com/twist and use the code TWiST to get a free welcome kit, five free travel sachets, and 10% off your order. 35:11 Yanez joins: How to prove personhood and uniqueness 38:32 How biometric capture and bio-keys work 40:05 Agent delegation: proving humans authorized AI agents 44:19 Bittensor Subnet 54 and incentivizing adversarial miners 47:11 Founder University Japan Cohort 2 applications open 49:15 Tech layoffs: Cloudflare cuts 20%, Coinbase cuts 14%, Block raises guidance 1:02:14 Anthropic's $50B round at $900B pre-money 1:04:22 WHOOP adds on-demand clinicians 1:06:42 Federalism, state-level regulation, and AI policy Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Lon: X: https://x.com/lons Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Check out all our partner offers: https://partners.launch.co/ Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com

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Om

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

Oplysninger

  • Skaber
    Jason Calacanis
  • Aktive år
    2009 - 2026
  • Episoder
    1,4 t
  • Vurdering
    Anstødeligt
  • Copyright
    © Jason Calacanis
  • Websted for serie
    This Week in Startups

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