Peptides Explained

John Garrett

Peptides Explained breaks down the most talked-about peptides and GLP-1 medications in health, fitness, and longevity — including semaglutide, tirzepatide, BPC-157, TB-500, and more. Hosted by Registered Nurse John Garrett, this podcast explains how these compounds work, why they’re popular, what the research shows, and the real risks and side effects — all in plain language. No bro science. No hype. Just clear, foundational education. For informational purposes only. Not medical advice.

Épisodes

  1. Episode 4 - Do Growth Hormone Peptides Actually Work? CJC-1295, Ipamorelin & Sermorelin Explained

    -21 H

    Episode 4 - Do Growth Hormone Peptides Actually Work? CJC-1295, Ipamorelin & Sermorelin Explained

    Growth hormone peptides are some of the most talked-about compounds in longevity medicine, metabolic health, and hormone optimization. But how do they actually work inside the body? In this episode of Peptides Explained, we break down the science behind four growth hormone secretagogues: Sermorelin, Tesamorelin, CJC-1295, and Ipamorelin. Instead of injecting growth hormone directly, these peptides stimulate the pituitary gland to release the body’s own growth hormone through different biological pathways. We explore the physiology of the growth hormone axis, the role of GHRH, IGF-1, and ghrelin signaling, and how these peptides may influence metabolism, recovery, and sleep. You’ll also learn the differences between these compounds, why CJC-1295 and Ipamorelin are often stacked, and what the clinical research actually shows. Topics covered in this episode include: • How growth hormone is regulated in the body• The biological role of ghrelin and GH pulses during sleep• The difference between Sermorelin, Tesamorelin, CJC-1295, and Ipamorelin• What DAC (Drug Affinity Complex) means in CJC-1295• Potential effects on IGF-1, metabolism, and recovery• Possible side effects, including effects on prolactin and glucose metabolism• What the clinical evidence actually supports As always, this podcast focuses on biological mechanisms and scientific evidence so you can understand how peptide therapies interact with human physiology. Disclaimer:This episode is for informational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional before considering any therapy. If you'd like, I can also give you a very effective pinned comment for the YouTube video. That small detail often increases engagement and pushes the algorithm to recommend the episode more.

    23 min
  2. 4 MARS

    Episode 3 - BPC-157 and TB-500 "The Wolverine Stack"

    In Episode 3 of Peptides Explained, we take a closer look at two of the most talked-about peptides in injury recovery circles: BPC-157 and TB-500. These compounds are often combined in what’s popularly called the “Wolverine Stack,” a nickname that reflects claims of accelerated healing and recovery. But what are these peptides actually doing in the body, and what does the science really say? In this episode, we break down the biology behind both compounds, how they interact with tissue repair pathways, and why they’ve become so popular in athletic and performance communities. We discuss: • What BPC-157 is and how it may influence angiogenesis, tendon repair, and tissue healing• What TB-500 (a fragment related to thymosin beta-4) does in terms of cell migration and tissue remodeling• The biological rationale behind combining the two peptides• What the available animal research suggests — and where human clinical data is still lacking• Why these peptides remain in a regulatory gray area• The difference between experimental compounds and FDA-approved peptide therapeutics The goal of Peptides Explained is clarity, not hype. In each episode we examine the mechanisms, the available data, and the real limitations of what we know today. Disclaimer:This podcast is for informational purposes only and does not constitute medical advice. Peptides discussed may have different regulatory statuses and should only be used under the guidance of licensed healthcare professionals. If you’re interested in the science behind peptides, injury recovery, metabolism, and emerging therapeutic pathways, this episode will give you a clear, evidence-based overview of one of the most talked-about peptide combinations today.

    26 min

À propos

Peptides Explained breaks down the most talked-about peptides and GLP-1 medications in health, fitness, and longevity — including semaglutide, tirzepatide, BPC-157, TB-500, and more. Hosted by Registered Nurse John Garrett, this podcast explains how these compounds work, why they’re popular, what the research shows, and the real risks and side effects — all in plain language. No bro science. No hype. Just clear, foundational education. For informational purposes only. Not medical advice.

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